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      • KCI등재

        A D-Band Integrated Signal Source Based on SiGe 0.18 μm BiCMOS Technology

        Seungyoon Jung,Jongwon Yun,Jae-Sung Rieh 한국전자파학회JEES 2015 Journal of Electromagnetic Engineering and Science Vol.15 No.4

        This work describes the development of a D-band (110?170 GHz) signal source based on a SiGe BiCMOS technology. This D-band signal source consists of a V-band (50?75 GHz) oscillator, a V-band amplifier, and a D-band frequency doubler. The V-band signal from the oscillator is amplified for power boost, and then the frequency is doubled for D-band signal generation. The V-band oscillator showed an output power of 2.7 dBm at 67.3 GHz. Including a buffer stage, it had a DC power consumption of 145 mW. The peak gain of the V-band amplifier was 10.9 dB, which was achieved at 64.0 GHz and consumed 110 mW of DC power. The active frequency doubler consumed 60 mW for D-band signal generation. The integrated D-band source exhibited a measured output oscillation frequency of 133.2 GHz with an output power of 3.1 dBm and a phase noise of -107.2 dBc/Hz at 10 MHz offset. The chip size is 900 × 1,890 μm², including RF and DC pads.

      • KCI등재

        Recognition of Respiratory Instability using a Photoplethysmography of Wrist-watch type Wearable Device

        Seungyoon Nam,John Lorenzo Bautista,Chanyoung Hahm,Hyunsoon Shin 대한전자공학회 2022 IEIE Transactions on Smart Processing & Computing Vol.11 No.2

        The photoplethysmography signal is composed of a cardiac-synchronous pulsatile waveform and different parts, which is modulated in amplitude by respiration. This paper presents a new indexing method similar to the apnea-hypopnea index and respiratory disturbance index for the self-diagnosis of sleep apnea symptoms (central and obstructed apnea) by using only a photoplethysmogram (PPG) signal. Sleep apnea is a sleeping disorder from several chronic conditions in which partial or complete cessation of breathing occurs many times throughout sleep at night. A respiratory rate signal (respiration-induced intensity variation) is modulated by synchronizing with the breathing rhythm extracted from PPG using a reflected light on the top of the wrist. This paper presents a new automated recognition and estimation method for daytime apnea and sleep-induced apnea using a wristwatch-type wearable device that can recognize irregular breathing using respiratory rate frequency-based features. The new respiratory effort strength index is proposed to quantify sleep apnea by determining how much a patient is suffering.

      • SCIESCOPUSKCI등재

        Databases and tools for constructing signal transduction networks in cancer

        ( Seungyoon Nam ) 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.1

        Traditionally, biologists have devoted their careers to studying individual biological entities of their own interest, partly due to lack of available data regarding that entity. Large, high-throughput data, too complex for conventional processing methods (i.e., “big data”), has accumulated in cancer biology, which is freely available in public data repositories. Such challenges urge biologists to inspect their biological entities of interest using novel approaches, firstly including repository data retrieval. Essentially, these revolutionary changes demand new interpretations of huge datasets at a systems-level, by so called “systems biology”. One of the representative applications of systems biology is to generate a biological network from high-throughput big data, providing a global map of molecular events associated with specific phenotype changes. In this review, we introduce the repositories of cancer big data and cutting-edge systems biology tools for network generation, and improved identification of therapeutic targets. [BMB Reports 2017; 50(1): 12-19]

      • KCI등재후보

        BACKGROUND OF ENTHUSIASM FOR EDUCATION IN TANZANIA

        Seungyoon Choi,Dong Ju Choi 한국외국어대학교 아프리카연구소 2019 Asian Journal of African Studies Vol.- No.45

        This research aims to analyze the motivating factors on high levels of enthusiasm for education in Tanzania. Specifically, the study categorized motivating factors by social, economic, and cultural & historical contexts. For social factors, international influence and domestic atmosphere such as media and parent’s education level can be motivating factors for educational enthusiasm in Tanzania. In economic factors, economic benefits and parent’s income level were selected. Lastly, for cultural & historical factors, the nature of ethnic groups and the influence of colonization were chosen as motivating factors for people in Tanzania to have high educational enthusiasm. The study findings from the quantitative analysis indicate that three motivating factors have significant correlations with educational enthusiasm in Tanzania. At the same time, through regression analysis, all motivating factors have positive impact on the enthusiasm for education in Tanzania by representing the highest impact on social factors followed by economic, cultural and historical factors. From the in-depth interview, the research finds out that people in Tanzania have very high level of educational enthusiasm. Specifically, interviewees emphasized economic factors as a leading motivating factor for educational enthusiasm in Tanzania. Moreover, education specialists emphasized the importance of cultural & historical factors as a motivating factors for educational enthusiasm in Tanzania.

      • KCI등재후보

        Prediction of Mammalian MicroRNA Targets - Comparative Genomics Approach with Longer 3' UTR Databases

        Nam, Seungyoon,Kim, Young-Kook,Kim, Pora,Kim, V. Narry,Shin, Seokmin,Lee, Sanghyuk Korea Genome Organization 2005 Genomics & informatics Vol.3 No.3

        MicroRNAs play an important role in regulating gene expression, but their target identification is a difficult task due to their short length and imperfect complementarity. Burge and coworkers developed a program called TargetScan that allowed imperfect complementarity and established a procedure favoring targets with multiple binding sites conserved in multiple organisms. We improved their algorithm in two major aspects - (i) using well-defined UTR (untranslated region) database, (ii) examining the extent of conservation inside the 3' UTR specifically. Average length in our UTR database, based on the ECgene annotation, is more than twice longer than the Ensembl. Then, TargetScan was used to identify putative binding sites. The extent of conservation varies significantly inside the 3' UTR. We used the 'tight' tracks in the UCSC genome browser to select the conserved binding sites in multiple species. By combining the longer 3' UTR data, TargetScan, and tightly conserved blocks of genomic DNA, we identified 107 putative target genes with multiple binding sites conserved in multiple species, of which 85 putative targets are novel.

      • SCISCIESCOPUS

        WNT5A Correlates with Clinicopathological Characteristics in Gastric Cancer: a Meta-Analysis

        Nam, Seungyoon,Chung, Jun-Won,Yang, Jun-Young S. KARGER AG 2017 CELLULAR PHYSIOLOGY AND BIOCHEMISTRY Vol.41 No.1

        <P><B><I>Background/Aims:</I></B> Gastric cancer (GC), the third-leading cause of cancer death in the world, is typically diagnosed only in its advanced stages. WNT signaling has been associated with clinicopathological characteristics in diverse cancer types. But the systematic analysis of WNT5A, a member in the signaling, has not been inspected. Thus, our study used a meta-analysis to statistically associate WNT5A expression with GC clinicopathological characteristics. <B><I>Methods:</I></B> For a systematic literature review of GC in combination with the WNT signaling molecule WNT5A, we searched for PubMed, Cochrane Library, and Web of Science. It led to the five cohorts, in four eligible studies, consisting of 1,034 patients (617 WNT5A-positive and 417 WNT5A-negative patients). These patients were inspected by the library “meta” in R software for our meta-analysis. <B><I>Results:</I></B> Our meta-analysis, revealed a statistically significant associations of WNT5A-positivity with lymph node metastasis (p=0.0047), some types of Lauren diffuse subtype GCs (p<0.0001), advanced tumor depth (p<0.0001), and advanced UICC stages (p=0.0461) with no observation of bias or confounding factors. <B><I>Conclusions:</I></B> These results support the feasibility of targeting this embryonic signaling pathway, both for therapy, and as a biomarker to “guide” various individual interventions (i.e., “personalized medicine”).</P>

      • Linking Cultural Capital With Subjective Well-Being and Social Support : The Role of Communication Networks

        Lee, Seungyoon,Chung, Jae Eun,Park, Namkee SAGE Publications 2016 Social science computer review Vol.34 No.2

        <P>This study examines the ways in which different forms of cultural capital are associated with college students' subjective well-being and social support. Results show that when social capital is accounted for, cultural capital derived from sports participation was positively associated with subjective well-being and social support. Further, the size and density of discussion networks about culture were positively associated with well-being and social support in general, while the heterogeneity of networks was negatively related. Findings from this study extend previous research on cultural capital by (1) drawing attention to the inclusive aspect of cultural capital, (2) examining online cultural participation as well as multiple forms of cultural activities including popular and sporting events, (3) applying the literature on interpersonal discussion networks to the context of culture and demonstrating the value of communicative action about cultural experiences, and (4) understanding the implications of cultural capital in a college setting.</P>

      • KCI등재

        연령별 온라인시민참여에 관한 연구 - 인터넷이용능력의 영향을 중심으로 -

        신승윤 ( Seungyoon Shin ),안선민 ( Sunmin Ahn ),김동욱 ( Dongwook Kim ) 한국정책학회 2017 韓國政策學會報 Vol.26 No.1

        대의민주주의의 대안으로 최근 그 중요성이 부각되고 있는 온라인시민참여는 비교적 젊은 연령층을 중심으로 참여가 활성화되어 있어 모든 연령층을 아우르지 못한다는 비판이 존재한다. 본 연구는 새로운 시민참여의 수단으로 자리 잡고 있는 온라인시민참여의 한정적 참여 문제에 대해 문제의식을 가지고 실제로 온라인시민참여에 있어 특정한 연령 효과가 존재하는지 실증적으로 검증해보고자 하였다. 또한 연령과 온라인시민참여의 관계 속에 연령과 음(-)의 상관관계를 보이는 인터넷이용능력이 온라인시민참여에 오히려 강력한 영향을 주는 요인일 수 있음을 가정하여, 온라인시민참여에 대한 인터넷이용능력의 영향도 검증해보고자 하였으며, 해당 분석은 다중회귀분석을 통해 실시하였다. 연구결과, 연령이 높을수록 온라인시민참여 수준이 저조한 것으로 확인되었지만, 이러한 효과는 또다른 독립변수인 인터넷이용능력 변수를 모형에 추가하였을 때, 해당 연령변수들의 온라인시민참여 수준에 갖는 통계적 유의성이 모두 사라지는 것을 확인할 수 있었다. 이를 통해, 온라인시민참여 수준에 대한 연령효과는 존재하지만, 이는 연령과 음(-)의 상관관계를 보이는 인터넷이용능력의 요인의 영향이 오히려 더욱 강력한 것으로 판단되며, 인터넷 이용능력의 일종의 매개효과를 확인할 수 있었다. 이에 따라, 상대적으로 고연령층의 인터넷이용능력을 증진시킨다면 온라인시민참여에 있어 모든 연령층의 참여를 제고시킬 수 있을 것이라는 정책적 시사점을 얻을 수 있었다. Recently, Online civic participation has become more important and has been considered as an alternative of representative democracy. However it is mostly activated by relatively young age group, so it is often criticized that it could not encompass all ages` participation. In this regard, this study tries to empirically analyze the age effect on online civic participation. Furthermore in the relation between age and level of online civic participation, internet literacy which has negative correlation on age could be the powerful factor on level of online civic participation, so it also analyze the effect of internet literacy with multiple regression model. Analysis results that people who have higher ages tend to participate less in online. However, the statistical significances of age variables disappear when internet literacy variable is added to each model. From the result, it can be concluded that the age effect exists in online participation, rather internet literacy is more powerful factor on level of online civic participation. Therefore this study give policy implication that if it is possible to enhance internet literacy level in higher age groups, the level of online civic participation in all ages might be improved.

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