Sarcomatoid Carcinoma Arising from Mature Cystic Teratoma

Ho-Chang Lee1, Seung-Myoung Son, Yong-Moon Lee, Ji Hae Koo, Song-Yi Choi, Ok-Jun Lee, Eun-Hwan Jeong 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.2

Malignant transformation of mature cystic teratoma (MCT) is rare. Sarcomatoid carcinoma is a neoplasm comprising malignant mesenchymal cells and a conventional carcinomatous area. Here, we report on a case of sarcomatoid carcinoma arising from an MCT in the left ovary of a 45-year-old female. A unilocular cyst consistent with MCT was observed; however, a nodule within the cyst was confirmed from the resected ovary. Microscopically, the nodule showed both squamous cell carcinoma and pleomorphic sarcomatous components admixing with each other. Lining epithelial cells at the periphery of the main tumor showed squamous metaplasia. When a sarcomatous component is observed in the ovary tumor, it is important to find a squamous cell component, either benign or malignant.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

달리기 질주속도 체감 및 질주동작 변용에 영향을 미치는 체력적 요인분석 : on the Upper Limbs

이승훈,신범철,이일구 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

The purpose of this story was to clarify the physical fitness factors influencing the decrease in speed and the change of motion during running with reference to the role of upper limbs. The subjects were twelve track and field athletes(decathletes). Running speed and kinematics parameters were obtained at the first phase and the final phase during the running with maximal effort. The subjects were examined Wingate anaerobic test(pedaling and arm cranking) and isokinetic muscular endurance test on three joints (shoulder, Knee and hip). The results were summarized as follows; 1) The higher anaerobic endurance capacity in arm cranking was, the smaller the reduction of running speed between the first phase and the final phase of running was. 2) There was significant correlation between the amount of difference about minimum hip angle and the muscular endurance rate of shoulder flexion(p<0.05). These results suggest that the anaerobic endurance capacity of upper limbs influences the decrease in running speed and the change of running motion during running. In addition, it is necessary to build up the anaerobic endurance capacity of not only lower limbs but also upper limbs in running.

글루코오스의 분해반응에 미치는 금속이온의 영향

이민규,이송우,허목,송승구 濟州大學校 工科大學 産業技術硏究所 1991 産業技術硏究報告 Vol.2 No.-

The objective of this research was to study the chemical kinetics of the decompo-sition of glucose in the presence of acid catalyst and metal ion. In this experiment. the range of variables investigated was covered temperature from 160℃ to 180℃ and concentration of 4% to 11% (W/V) sulfuric acid and metal sulfate concentrations, 1.0×10^(-3) to 2.5×10^(-2) gmol/l. It is shown that glucose disappearance follows a first-order reaction mechanism and the glucose decomposition reaction is dependent on both the reaction temperature and the catalyst concentration. And the presence of chromic ion accelerates the decompo-sition reaction of glucose, but presence of ferric and nickel ion rarely influence the reaction.

복합재료 적층판의 고유진동수에 대한 하중크기의 영향

이승식,한봉구 서울산업대학교 2005 논문집 Vol.54 No.1

The Special orthotropic plate theory is used for analysis of panels made of steel girders and cross-beams, and made of reinforced concrete. The cross-sections of girders and cross-beams are WF types. The result is compared with that of the beam theory. According to the numerical examination given in this paper, the result by the plate theory is 2.43 times stiffer than that of beam theory. The result for the concrete slab in given for the practicing engineers.

양안 근점거리의 분포형

구정완,오민화,이승한 가톨릭대학산업의학센타 산업의학연구소 1991 韓國의 産業醫學 Vol.30 No.2

Near point distance for both eyes of 71 healthy subjects. who no special eye conditions, were measured in order to clarify their distribution form and to select a measure that is suited to continuous observation of visual fatigue of VDT workers. The results were as follows: 1. Near point distance for both eyes(appear. disappear) followed normal distribution only after natural log-transformation(Shapiro-Wilk test). 2. The variance and the coefficient of variation of near point distance(appear) were 0.04 and 4.13, respectively, while they were 0.08 and 6.30 in near point distance(disappear). The findings suggested that near point distance(appear) could be a preferable measure to near point distance(disappear)in the sequential monitoring of visual fatigue. 3. The mean near point distance(appear, disappear)for both eyes of study subjects were 138,82 mm in the age4 group of 20-29 years and were 156,97 mm in the age group of 30-39 years. respectively.

압출성형에 의한 국산 무연탄 활성탄의 세공구조 변화

이송우,문장천,김도한,이창한,최동훈,류동춘,송승구 부산대학교 환경문제연구소 2000 環境硏究報 Vol.18 No.-

The purpose of this study is to investigate the variation of pore size distribution of the coal-based extruded activated carbon. The extruded activated carbon was prepared by extruding the mixture of coal powder and coal tar. Pore size distribution of the extruded activated carbon was compared with that of the extruded coal and the extruded char. Also it was compared with that of the crushed activated carbon, raw coal and char. The extruded coal had coarser surface than that of raw coal. Macropores of the extruded coal were funned near 10,000Å in diameter during carbonization process and steam penetrated easily between particles and were growing between 3,000Å and 20,000Å in diameter during activation process.

글루코오스의 분해반응에 미치는 금속이온의 영향

이민규,허목,이송우,송승구 濟州大學校工科大學附屬産業技術硏究所 1991 尖端技術硏究所論文集 Vol.2 No.-

The objective of this research was to study the chemical kinetics of the decomposition of glucose in the presence of acid catalyst and metal ion. In this experiment, the range of variables investigated was covered temperature from 160℃ to 180℃ and concentration of 4% to 11%(W/V) sulfuric acid and metal sulfate concentrations, ?? to ??g㏖/l. It is shown that glucose disappearance follows a first-order reaction. mechanism and the glucose decomposition reaction is dependent on both the reaction temperature and the catalyst concentration. And the presence of chromic ion accelerates the decomposition reaction of glucose, but presence of ferric and nickel ion rarely influence the reaction.

인삼투여가 체력 및 체중감량에 미치는 영향

이명복,김창규,박성순,김귀봉,이상구,김현덕 국민대학교 스포츠과학연구소 1985 스포츠科學硏究所論叢 Vol.4 No.-

The purpose of the study was to investigate and find the metabolic and strength response to the effects of Gin Seng intake on weight reduction in Wrestlers. Ten subjects experienced five to eight years fro were used for the study. They are attending at university and engaging in wrestling program. The subjects were divided into experimental and control groups. Five exeprimental group was supplemented Korean Gin Seng with the amounts of 600g for eight weeks. The pre-post test methods was conducted. The metabolic test using the Ergo-Oxyscreen (Jager co. German) were obtained during the ergometer bicycle tests. The subjects were seated on the bicycle for two minutes after two minutes resting period, and pedalled with 60rpm at the beginning with free loading for two minutes, and increased the 0.5KP load every one minute. The exercise on the bicycle was continued until the subjects were exhausted. The metabolic data such as weight, MV(minute ventilation)., BF(breathing frequency), Heart rate, Vo_2ml kg/min., and Time. were calculated automatically and printed out the data every minute. The grip and back strength tests were obtained using the dynamometer (T.KK. Japan), and leg strength(180/sec, 30/sec.), power, isometric maximal strength, and endurance were measured through Cybex-Ⅱ system. After pre-test, exprimental group was begin to intake Gin-Seng for eight weeks, and control was start to reduce their body weight. As the results of the study, conclusion to be drawn as follows; 1. There were no significant difference between before weight reduction and after weight

한국인에게 적절한 기관삽관 위치

이승한,최옥경,정구영,정성필 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

Endotracheal intubation is one of the important procedures in ED and various fields. Endobronchial intubation can lead to hypoxemia secondary to tension pneumothorax of intubated side and atelectasis of contralateral side. The placement of tube beyond the vocal cords may results in inadvertent extubation, larygeal spasm and aspiration pneumonia. The conformation methods of endotracheal intubation are auscultation of the chest, observation of a vapor trail, oximetry and capnography, and radiologic evaluation. Owen and associates recommended that oral intubation tubes at the upper incisor teeth at the 23cm in men and the 21cm in women of average adult size would have led to proper placement. We studied that whether the proper depth of endotracheal tube in American is appropriate to Korean. We studied adult patients admitted to ED (of both hospitals during March in 1995. Endotracheal tubes in men were positioned at the 23cm and women had positioned at the 21cm at the upper incisor teeth. The distance of the tip of the endotracheal tube to the tracheal carina on the postintubation chest X-ray then determined. Correct placement of intubation was defined with the tip of the tube≥3cm above the carina and below the level of the larynx. Fifty adult patients were enrolled in the study ; 29 men (58%) and 31 women (42%). Mean height and weight were 170±5.2cm, 68±9kg in men and 158±6.5cm, 56±10kg in women. Reasons for intubation were ; respiratory failure(38%), trauma(16%), increased intracramial pressare(16%), drug intoxication(12%), shock(8%), cardiac arrest(7%)and others(3%). The mean distance from the tip to carina on chest X-ray was 4.13±1.5cm in men and 3.45±2.1cm in women. Proper position was 27/29(93%) in men, 14/21(67%) in women or 41/50(82%). this means the placement of endotracheal tube of our patients was positioned deeper than prion study group(97.6%).(p<.05) We recommend that the 22cm tube mark for men and 20cm tube mard for women at upper incisor teeth would have led to proper placement in Korean adult patient.