한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

茵蔯淸肝湯이 肝保護 및 纖維化 抑制에 미치는 影響

승현석,김영철,이장훈,우홍정 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Objective : The aim of this study is to investigate the inhibitory effect of Injinchunggantang on hepatic sclerosis induced by CCl₄. Methods : Weight, liver function test and complete blood cell count, gross findings, and findings on liver tissue of the past(Hematoxylin & Eosin stain, Masson-Trichrome stain) were studied. Results : When it comes to the change of rats body weight, The CCI₄-Injinchunggantang group lost far less weight than The CCl₄ only group. In the liver function test, which is focused on various area such as total cholesterol, alkaline phosphotase albumin, aspartate transaminase, alanine transaminase, The CCl₄ Injinchunggantang group was much more closer to normal limit than the CCl₄ only group. In the complete blood cell count, including while blood cell, red blood cell, hemoglobin, hematocrite, platelet, The CCl₄ Injinchunggantang group significantly closer to normal limit than CCl₄ only group. In the gross findings of hepatic fibrosis models, Injinchunggantang showed inhibitory effect on hepatic fibrosis in the order. In the past findings of hepatic fibrosis models in Hematoxylin & Eosin, Masson-Trichrome staining, the liver in CCl₄ only group showed atrophy and necrotic change with white nodules, whereas that of CCl₄ Injuchuinggantang group showed lesser significant change with the well preserved tone of the tissue. In the extent of the inhibition of the hepatic fibrosis, the Injinchunggantang group showed statistically significant inhibitory effect(p<0.05) in the sclerosis model. Conclusions : These results show that Injinchunggantang have inhibitory effect on hepatic sclerosis induced by CCl₄ and further ultimately prevent liver cirrhosis. To obtain more credible results in the experiment, the invention of a new experimental model more similar to human hepatic sclerosis is still needed.

MATLAB을 이용한 자동차 엔진모델 설계 및 시뮬레이션

장종승,설재훈,김승철,임영도 東亞大學校 附設 情報通信硏究所 1997 情報通信硏究所論文誌 Vol.5 No.1

Detailed model of longitudinal dynamics of a typical automobile is developed. A nonlinear controller is designed for speed control of the automobile. This paper discribes the first step of a vehicle model design which designs a engine model. The design of a vehicle engine designs Matlab Simulink, and control which is compared describes characteristics be using Fuzzy and PID.

Flavobacterium meningosepticum에 의한 균혈증 1예

장성원,유진홍,진승원,김선우,김연식,박순민,이대훈,최민호,최주연,신완식,강문원,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.1

1996년 6월 카톨릭대학교 부천성가병원에 뇌경색으로 입원했던 61세 남자 환자의 혈액에서 Flavobacterium meningosepticum을 분리하였다. 환자는 폐렴을 동반한 패혈증의 예로 ceftriaxone과 metronidazole을 투여하였으나 입원 48시간만에 사망하였다. Flabovacterium meningosepticum is a rae cause of nosocomial infection which shows multi-drug resistance. It mainly invades patients with impaired immunity. Recently, we experienced a case of F. meningosepticum bacteremia in a patient with chronic debilitated state owing to stroke. The clinical progress was so rapid that he died within 48 hours. Blood culture revealed F. meningosepticum which showed characteristic yellow colony in blood agar plate.

FA/MA 방법에 의한 부산시 부유분진의 오염원 할당

정장표, 이승훈, 윤항묵 경성대학교 환경문제연구소 2000 環境硏報 Vol.10 No.1

The object of this study was to identify source categories of Busan area through FA/MA methodology which contribute to the concentration of suspended particles at receptor. According to the purpose of this study, twenty-seven chemical species such as elements, anions, and total carbon of chirty-six PM10 and TSP data sets sampled at Bumchun receptor site for a 24hr period from May to Aug. 1992, were analyzed and applied to FA/MA model. From this study, the following conclusions were obtained. From the factor analysis for measured data, steel, mill-related, transportation, soil dust resuspension, marine, fuel oil, secondary aerosol source, and etc., of which total variance explained by the identified factors was calculated as 84 ∼ 91%, were identified. And the trend was shown that the more the number of input trace materials was, the more difficult the identifications of factors were, relatively. Selecting the representive tracers for identified factors based on the factor loadings, the following equations were obtained by use of stepwise method in multiple linear regression for the cases. TSP(㎍/㎥) = 27.996+0.033Mg +0.016Cl-+0.O05SO42 Case 1 TSP(㎍/㎥) = 11.779 + 2.013Ti + 0.034Na + 0.026Mg + 0.006ca Case 2 PM10(㎍/㎥) = 3.130+0.O04 SO42 +0.010 Cl- + 1.812Ti Case 1 PM10(㎍/㎥) = -14.028+1.515Ti +0.D38Na + 0.O09 Cl- + 0.003 SO42- Case 2 In comparison with the results of FA/MR model with the change of the newly added input tracers, the case with TSP showed relatively unstable results of factor analysis for the case studies because of insufficient number of data available to complete a factor analysis for the tracers used.

물표면채집기를 이용한 부산지역의 대기건성침적특성

정장표,이승훈 慶星大學校 環境問題硏究所 1998 環境硏報 Vol.8 No.1

Atmospheric dry deposition involves the transport and removal of aerosols and gases from atmosphere onto surfaces in the absence of precipitation, which is an important mechanism in controlling the fate of airborne toxic pollutants and their movements from the atmosphere to natural surfaces. In spite of increasing awareness of the importance of dry deposition in the fate of airborne pollutants, many uncertainties exist on the methods for calculation and measurements of dry deposition. One of the most pervasive problems in studies of air toxics is our inability to adequately measure or model dry deposition. The establishment of monitoring methodology and the evaluation of dry deposition characteristics that can accurately measure and estimate the dry deposition of airborne toxics to water bodies is imperative to prevent water bodies from being contanimated and to establish the management policies of water quality conservation. In this study, the flux of sulfate(SO??), nitrate(NO??) and chloride Cl?? measured in Pusan were (28.77. 21.86), (8.85, 5.18), (4.53, 2.69) ㎎/㎡/day, respectively. In addition the ratios of daytime fluxes to nighttime fluxes were 1.32, 1.71 and 1.68. From the above results, the fluxes of daytime showed higer than those of nighttime for all three acidic aerosols. 2. By the results of the differences in fluxes of SO?? and NO?? by the sample sites, the total average fluxes of SO?? in Chicago, Seoul and Pusan were 24.15, 21.50, 25.32 ㎎/㎡/day respectively, which showed similar flux levels. And the flux of NO?? in Pusan was 6.39 ㎎/㎡/day which was higher than 5.08 ㎎/㎡/day in Seoul. 3. The particle size distribution analysis for the samples of water surface showed that the particle size ranged from 30 ㎛ to 400 ㎛ and the particle distribution curve showed typically bell type of one peak. But the particle distribution curve was irregular type of multi-peaks and the particle size ranged from sub-micron to 400 ㎛ for the samples of dry deposition plate.

뇌하수체 선종내 출혈의 임상분석

이봉훈,김오룡,김성호,배장호,최병연,조수호 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.5

Weibull분포함수를 이용한 CPRI의 성능평가

정장표,이승훈 慶星大學校 環境問題硏究所 1999 環境硏報 Vol.9 No.1

Atmospheric dry deposition involves the transport and removal of aerosols and gases from atmosphere onto surface which is an important mechanism in controlling the fate of airborne toxic pollutants and their movement. In spite of increasing awareness of the importance of dry deposition in the fate of airborne pollutants, many uncertainties exist on the methods for calculation and measurements of dry deposition. The establishment of monitoring methodology that can accurately measure thedry edposition of airborne toxics to water bodies is imperative to prevent water bodies from being contaminated and to establish the policies managing water quality effectively. In this study, the performance evaluation of CPRI which was newly developed sampler for the coarse particle range deposition was carried out through the statistical comparison between the measured value and calculated value by the Weibull probability distribution function. The Weibull probability distribution function was well fitted for all the sample data obtained by CPRI which showed various concentration levels. We concluded that the performance of CPRI is relatively high from the result obtained by the staistical t-test that there was no difference between measured data and calculated data.

부산시 자동측정망자료의 Weibull 확률분포함수 적용 및 기준치 적합성평가

정장표,이승훈 경성대학교 공학기술연구소 1998 공학기술연구지 Vol.5 No.-

The urban air quality in Korea has been deteriorated due to the rapid urbanization, industrialization and sudden increase of traffic volume. To scope with the air pollution problems, we need to establish the effective air quality management strategies based on evaluating the status of pollution and characteristics of concentration through the continuous monitoring. Also, We need to not only assess the degree of air pollution accurately based on the ambient air quality standards, but also check out whether the ambient air quality standards were properly established. From this study, it was obtained that concentration distribution for the criteria-pollutants measured at eight-air monitoring networks in Pusan area in 1997, was well fitted to Weibull probability distribution function. And the degree of differences from air quality standards and the expected values obtained from Weibull concentration distribution function were in order of CO(0.83∼0.90)〉SO₂(0.45∼0.80)〉TSP(0.24∼0.53)〉NO₂(0.23∼0.45)〉O₃(0.11∼0.30) in Pusan Area.

PCA와 ANN을 이용한 VOC 측정기기 개발

이장훈,권혁구,박승호,김동진,홍철호 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.2

Air quality monitoring is a primary activity for industrial and social environment. The government identifies the pollutants that each industry must monitor. Especially, the VOCs(Volatile Organic Compounds), which are very harmful to human body and environment atmosphere, should be controlled under the government policy. However, the VOCs, which have not been confirmed in emission sources are very difficult to monitor. It is needed to develop the monitoring system that allow the continuous and in situ measurement of VOCs mixture in different environmental matrices. Gas chromatography and mass spectrometry are the most prevalent current techniques among those available for the analysis of VOCs. But, they need a large size analytical instrument, which costs a great deal for purchase and operation. In addition, it has some limitations for real time environmental monitoring such as location problems and slow processing time. Recently, several companies have commercialized a portable VOCs measurement systems, which cannot classify various kinds of VOCs but total quantities. We have developed a VOCs measurement system, which recognizes various kinds and quantities of VOCs, such as benzene, toluene, and xylene(BTX). Also, it can be used as a stand-alone type and/or fixed type in the vehicle with rack for real-time environmental monitoring.