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Yoon, Seokho,An, Young-Sil,Lee, Su Jin,So, Eu Young,Kim, Jang-Hee,Chung, Yoon-Sok,Yoon, Joon-Kee Wolters Kluwer Health 2015 Medicine Vol.94 No.48
<P><B>Abstract</B></P><P><I>BRAFV</I>600E mutation and F-18 fluorodeoxyglucose (FDG) uptake are potential prognostic factors of papillary thyroid cancer (PTC). This study was performed to investigate the relationship between the <I>BRAFV</I>600E mutation and F-18 FDG uptake in PTC.</P><P>We retrospectively included 169 PTC patients who underwent F-18 FDG positron emission tomography/computed tomography (PET/CT) before thyroidectomy from May 2009 to August 2012. Subjects were classified into overt PTC (>1 cm, n = 76) and papillary thyroid microcarcinoma (PTMC, n = 93) groups. Univariate and multivariate analyses were performed to assess the relationship between maximum standardized uptake value (SUV<SUB>max</SUB>) of the primary tumors and clinicopathologic variables.</P><P>The <I>BRAFV</I>600E mutation was detected in 82.2% (139/169). In all subjects, the <I>BRAFV</I>600E mutation and tumor size were independently related to SUV<SUB>max</SUB> by multivariate analysis (<I>P</I> = 0.048 and <I>P</I> < 0.001, respectively). SUV<SUB>max</SUB> was significantly higher in tumors with the <I>BRAFV</I>600E mutation than in those with wild-type <I>BRAF</I> (9.4 ± 10.9 vs 5.0 ± 4.1, <I>P</I> < 0.001). Similarly, in overt PTC group, the <I>BRAFV</I>600E mutation and tumor size were independently correlated with SUV<SUB>max</SUB> (<I>P</I> = 0.032 and <I>P</I> = 0.001, respectively). By contrast, in PTMC group, only tumor size was significantly associated with SUV<SUB>max</SUB> (<I>P</I> = 0.010).</P><P>The presence of the <I>BRAFV</I>600E mutation is independently associated with high F-18 FDG uptake on preoperative PET/CT in patients with overt PTC, but this relationship was not evident in PTMC. This study provides a better understanding of the relationship between F-18 FDG uptake and <I>BRAFV</I>600E mutation in patients with PTC.</P>
Analysis of Intersymbol Interference due to Overlap in DM-BPSK
YOON, Taeung,LEE, Youngpo,PARK, So Ryoung,KIM, Suk Chan,SONG, Iickho,YOON, Seokho The Institute of Electronics, Information and Comm 2010 IEICE TRANSACTIONS ON COMMUNICATIONS - Vol.93 No.5
<P>The relationship between the degree of overlap in direct modulation chirp spread spectrum systems with binary phase shift keying and intersymbol interference (ISI) is analyzed. It is observed that the ISI due to overlap fluctuates or monotonically increases as the number of overlaps changes and that, in some cases, the overlap does not incur ISI at all.</P>
Seokho Yoon,Suk Chan Kim,Jun Heo,Iickho Song,Sun Yong Kim IEEE 2009 IEEE Transactions on Vehicular Technology VT Vol.58 No.4
<P>As a novel code-acquisition scheme, the twin-cell detection (TCD) is proposed for the acquisition in time of spread-spectrum codes in the presence of fractional Doppler frequency offset (FDFO). When the FDFO exists, the correlation peak that is used for detection during the acquisition process is split into two neighboring peaks with smaller magnitudes, which results in a considerable degradation in the overall acquisition performance of conventional schemes. In the TCD, the decision variable for detection is formed by combining two consecutive correlator outputs so that the influence of the reduction in the correlation peak due to the FDFO can be alleviated. The numerical results show that the TCD can offer a better mean-time-to-synchronization performance than the conventional scheme based on the cell-by-cell detection.</P>
A Closed Form BER expression for an Overlap-based CSS System
Taeung Yoon,Seung Hwan Yoo,Sun Yong Kim,Seokho Yoon 대한전자공학회 2008 ITC-CSCC :International Technical Conference on Ci Vol.2008 No.7
Overlap is one of the techniques for increasing bit rate in CSS. More overlaps can offer higher data throughput; however, they may cause more intersymbol interference (ISI) at the same time, resulting in serious bit error rate (BER) performance degradation. This implies that the number of overlaps should be decided according to the required system performance. In this paper, we derive a closed form expression for BER of the overlap-based CSS system, which would be very helpful in setting the number of overlaps. The numerical results demonstrate that the BER derived in a closed form closely agrees with the simulated BER.