개에서 발생한 다중심성 T 세포 림프종 증례

이기호,박형진,송근호,서경원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 5-year-old Jindo dog (13.7 kg, intact female) with history of cervical mass was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Complete blood cell count showed mild anemia thrombocytopenia. And serum biochemistry showed increased ALP. On radiologic evaluation, multicentric lymph nodes' enlargement. Based on the findings, the dog was diagnosed as multicentric T-cell lymphoma. The dog was treated with LCOAP-short protocol, but survived 7 months since first finding.

매쉬-심 용접 판재의 성형 한계

김형목,허영무,양대호,서대교 기계기술연구소 1999 성균관대학교 논문집 기계기술편 Vol.1 No.1

This paper describes experimental investigation on the forming limit for mash-seam welded sheets. The uniaxial tensile test was conducted to evaluate the mechanical properties of weld bead. Experimental forming limit diagrams were investigated for the different thicknesses and properties of welded sheets.

금속복합재료를 이용한 가솔린 엔진 피스톤의 제조

서영호,이형국 동의공업대학 2001 論文集 Vol.27 No.1

Aluminum matrix composite automotive parts, such as diesel engine pistons or engine blocks are produced using squeeze casting apparatus or pressure die-casting apparatus. But the solidification process gets complicated with manufacturing parameters and the factors for porosity formation have not fully understood yet. The formation of porosity during squeeze infiltration has been studied experimentally to achieve an improved understanding of the squeeze infiltration process for manufacture of short-fiber-reinforced components, particularly the mechanism of porosity formation. The development of a product with metal matrix composites was focused on a gasoline engine piston on the basis of fundamental experiments. Environmental concern is one of major issues in many advanced countries and the new technology utilizing new materials is considerable industrial importance. The wearing of ring land area of pistons can cause not only serious problem in air pollution but reducing engine efficiency. However, the process of making pistons is poorly understood in Korea. The objective of this study improve the competitive of automobile companies through the establishment of optimum condition on automotive component fabrication by squeeze infiltration process.

어린 개에서 발생한 선천성 특발성 거대도식증 1례

서동규,박형진,송근호,서경원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

Three-month-old, intact male, weighting 2.6 kg. Dachshund dog visited to the Veterinary Medical Teaching Hospotal of Chungnam National University with history of regurgitation. Result of blood analysis was in the normal range. On the radiographic examination, diffuse esophageal dilatation was observed. On the esophagram, esophageal dysmotility was observed. Acetylcholine receptor antibody titer was in the normal range. On the endoscopy, esophagitis was observed. Diagnosis was congenital idiopathic megaesophagus. This is the case report of congenital idiopathic megaesophagus.

개에서 발생한 파열된 전이성 비장 혈관육종 1례

서동규,박형진,송근호,서경원 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

Twelve-year-old, catrated male, weighting 8 kg, Miniature Schnauzer dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with history of depression. Result of blood analysis revealed anemia, thrombocytopenia, azotemia, elevated ALP, ALT and CK. On the radiographic examination, splenomegaly and loss of abdominal serosal detail were observed. Abdominal ultrasonography showed rounded mass of spleen and liver, ascites were observed. Splenectomy was performed and found that splentic tail had been ruptured and two samples from nodules on liver were obtained for histopathology. The result of biopsy revealed that hemangiosarcoma of spleen metastasized to the liver. Carboplatin was chosen as the patient had congestive heart failture. During chemotherapy hemangiosarcoma was metastasized into peritoneum and abdominal cavity. Intraperitoneal chemotherapy was preceded at this moment. After 99 days of initial visit, patient was euthanized due to severe anemia and thrombocytopenia.

Dictyostelium discoideum의 세포융합

최호형,이기현,서정열 公州大學校 基礎科學硏究所 1996 自然科學硏究 Vol.5 No.-

Dictyostelium discoideum에서 세포 융합율을 높이기 위한 최적조건들을 찾기 위해서 세포 융합율이 빛, 온도, pH 그리고 ?? 의해 어떻게 영향을 받는지를 조사하였다. 빛이 있는 조건 하에서 배양시킨 HN₁과 NC₄를 혼합하였을 때 융합율은 10% 낮아졌다. 빛이 있는 조건하에서 배양된 HN₁과 빛이 없는 조건하에서 배양된 NC₄를 혼합하였을 때 융합율은 위와 같다. 그러나 빛이 없는 조건하에서 배양된 HN₁과 NC₄를 혼합하였을 때 융합율은 60% 높아졌다. 10℃ ~ 25℃ 사이에서 모든 세포들은 융합할수 있지만 시간적인 차이를 보였다. pH 5.5-6.5에서 융합율이 가장 높으며 ?? 농도는 500μM 일때 가장 효과적이고 200μM의 농도는 영향을 미치지 못했다. 그러므로 D. discoideum에서 세포융합을 증진시키는 최적조건들은 : 빛이 없는 조건하에서 HN₁과 NC₄를 배양시키고, pH 5.5, 20℃ 또는 25℃의 온도 그리고 500μM의 ?? 농도이다. In order to find the optimum conditions to raise the rate of cell fusion in Dictyostelium discoideum, we investigated how the rate of cell fusion was affected by light, temperature, pH and ??. When HM₁ and NC₄ cultured in light were mixed, the fusion rate of these was lower by 10%. When HM1 cultured in light and NC4 cultured in dark were mixed, the fusion rate was the same as above. But when HM₁and NC₄both cultured in dark were mixed, the fusion rate was 60% higher. In the range of 10℃∼25℃, all cells can fuse but there was a difference of time. The fusion rate was the highest in pH 5.5∼6.5, and the concentration of ?? was the maximum effective at 500μM and had no effect at 200μM. Therefore, the optimum conditions to elevate the cell fusion rate in D. discoideum were : HM₁and NC₄, that both cultured in dark, pH 5.5, temperature of 20℃ or 25℃ and 500μM ??.

잔존 봉합사에 의해 발생한 점액종

이제호,최병재,서원건,최형준 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.4

점액종이란 소타액선 분비관의 폐쇄 또는 파열로 인한 타액의 저류로 나타나는 종창에 대한 임상적인 용어이다. 점액종은 조직학적으로 삼출형과 잔류낭종형으로 분류되어, 삼출형은 외상등으로 소타액선 분비관이 파열된 후 점액이 조직내로 유출되어 조직간격에 고여있는 상태이기 때문에 상피 피복을 볼 수 없고 낭종벽은 육아조직으로 둘러싸여있다. 그리고 잔류낭종형은 소타액선 분비관이 작은 타석에의해 폐쇄되거나 분비관 주위 반흔조직의 협착으로 발생하며 낭종강은 원주상피 또는 위중층 편평상피로 피개되어있다. 본 증례는 3년전 하순의 열창 치료를 위해 봉합된 후 발사되지 않은 silk 봉합사에 의해 발생한 점액종의 치험례로, 발사되지 않은 봉합사가 하순 소타액선의 분비관을 관통하여 파열시켜서 점액이 결체조직으로 유출되어 점액종이 발생하였다. Mucocele is clinical term used to describe swelling caused by the pooling of saliva at the site of a severed or obstructed minor salivary gland duct. Mucoceles are categorized into two subgroups, extravasation type and retention cyst type. The etiology of extravasation type mucocele is related to mechanical trauma to the minor salivary gland excretory duct, resulting in extravasation of mucus into the fibrous connective tissue so that a cystlike cavity is produced, but the epithelial lining is absent. Retention cyst type mucocele results from obstruction of minor salivary gland excretory duct, and cystic cavity is lined by epithelial cells. This case report presents a mucocele occurred on the lower lip, and caused by suture silk unremoved for 3 years. Suture silk penetrated and tore the minor salivary gland duct on the lower lip with subsequent extravasation of mucus into the fibrous connective tissue.

폐모세포종 : 1례보고 A Case Report

최영호,서홍주,임영혁,김정중,박성강,이석기,임진수,김은규 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Pulmonary blastoma is a very rare primary neoplasm of the lung. We experienced a case of pulmonary blastoma in a 40 years old man. The mediobasal segmentectomy of the right lower lobe was performed. The patient was discharge on the postoperative days 6. There is no evidence of recurrence or metastasis on followup study during 7 months period after operation.

개심술(開心術)의 임상적 고찰 : 치험 200예 200 Cases

최형호,서홍주,임영혁,김정중,배대양,이석기,임진수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

Background and Objectives: Two hundred cases of the open heart surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 2001. Material and Methods: The number of congenital heart disease was 132 cases. 68 cases were acquired heart disease. 'The age of the congenital heart disease was from 22 days to 45 years. In the acquired heart disease, the age was from 14 to 72 years. Result: Congenital heart disease consisted of 113 congenital acyanotic heart disease, 19 congenital cyanotic heart disease. Corrective operation was done for congenital heart disease with 4. 5 % operative mortality. Of 68 cases acquired heart disease, 44 patients were valvular heart disease, 3 cardiac tumors, 9 ischemic heart diseases, 12 aortic dissections and etc. The operative mortality was 13%. Conclusion: The postoperative complications were appeared in 68 cases and the complications were wound infection, occipital alopecia, low cardiac output syndrome, arrhythmia, septicemia etc. The mortality after open heart surgery was 15 cases and the causes of death were low cardiac output syndrome, septicemia, respiratory failure and left ventricle rupture.

족삼리의 전기침 자극에 대한 개구반사 크기의 변화

이상호,나창수,송형근,서영아 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.4

The purpose of this study was to investigate the effect of various electroacupuncture duration induced by acupuncture point-Zusanli(S36) electrical stimulation on inhibition of amplitude of digastric electromyogram (dEMG)evoked by noxious electrical stimuli around the mental foramen. <Experiments were conducted on adult rats (SD) were anesthetizde with> intraperitoneal sodium pentobarbital in an initial dose of 50mg/kg and maintenance doses of 4.5mg/kg/h were given through a cannula in the femoral vein using a constant infusion pump. A pair of stimulating electrodes were inserted for noxious stimuli around the mental foramen. An irritant electronic stimuli pulse (0.2 Hz,0.1 ms duration) was produced with an intensity of about 1.5-2 times threshold for evoking the dEMG. The anterior belly of the digastric muscle was exposed and a pair of 0.1mm wire electrodes were inserted for dEMG recording. Acupuncture point stimulation on Zusanli (2 Hz, 250㎲, biphasic pulse. 2 V) was delivered by Dental Electronic Anesthesia (3M,U.S.A). For periods of electronic stimulation of 10, 20, and 30min, the amplitudes of dEMG were measured on the oscilloscope and on the monitor connected to the amplifier. The following results were obtained: The dEMG was decreased to 73.4% of that in the control set after 10 min electroacupunture stimulation (Group Ⅰ): The dEMG was decreased to 77.1%(10min), 54.0% (20min)of that in the control set after 20minutes of electroacurunture stimulation (Group Ⅱ). The dEMG was decreased to 73.7% (10min), 61.9%(20min), 76.2%(30min) of that in the control set after 30 min of electroacupunture stimulation (Group Ⅲ). From these results, it may be that in the electroacupuncture stimulation on the Zusnali resulted in a reduction of amplitude of daEMG and that the most effective electroacupuncutre stimulation period was 20min.