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N. Pugazhenthiran,S. Murugesan,H. Valdés,M. Selvaraj,P. Sathishkumar,P.G. Smirniotis,S. Anandan,R.V. Mangalaraja 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.105 No.-
In this study, 250 nm sized porous anatase TiO2 nanospheres (TiO2 NSPs) composed of 10 nm sized anataseTiO2 nanoparticles are obtained through a green synthetic route and their surfaces have been decoratedwith 3–4 nm sized plasmonic silver nanoparticles (AgNPs). Photoluminescence studies confirm thatthe AgNPs presence on TiO2 NSPs surface effectively inhibits the radiative charge recombination and thusfacilitates charge separation process at the Ag-TiO2 NSPs interface, causing an enhanced photocatalyticactivity. About 92% of the ceftiofur sodium (CFS) antibiotic taken initially is oxidized by Ag-TiO2 NSPsupon 90 min white light irradiation, while Ag loaded Degussa P25 TiO2 nanoparticles effects only 71%CFS oxidation. The synergistic effect given by plasmonic AgNPs and the continuous framework of anataseTiO2 NPs contributes to inhibit the electron-hole recombination in the Ag-TiO2 NSPs. Oxidation productsof CFS in different water sources and their eco-toxicity effects identified through LC-MS and microtoxbioassays,respectively, indicate that the obtained oxidation products are non-toxic compared to pureCFS. Therefore, porous Ag-TiO2 NSPs could be successfully applied in photocatalytic oxidation technologies,exploiting sunlight for the effective removal of pharmaceutical pollutants from wastewater.
Reducing the seat vibration of vehicle by semi active force control technique
Sathishkumar. P.,Jancirani. J.,Dennie John 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.2
This article focusses on reducing the axis acceleration and minimizing the vertical displacement by using an air spring actuator and activeforce control as a main control element. In active force control loop track the developed force of an air spring actuator is fed as afeedback to the actuator. Mamdani and sugeno type fuzzy interference system are used to develop a desired force and to estimate mass ofthe system respectively. The performance of the system is analyzed for both time and frequency domains and contrasted with passivesuspension due to the irregular road disturbances. While developing the simulation model, quarter car suspension with seat as three degreeof freedom and an air spring actuator acting as a force generator are modeled as non-linear system. The simulation result shows theeffectiveness of the proposed control scheme in suppressing the undesirable effects of the suspension system.
S. Sreeram,R. Sathishkumar,P. S. Amritha 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.2
Human Immunodeficiency Virus (HIV) infects human by destroying the immune system. The types of HIV strains HIV-1 and HIV-2, among HIV-1 being more prevalent and considered deadly. Eventually either of the strains leads to disease Acquired Immunodeficiency Syndrome (AIDS). Traditional medicinal plants have a pivotal role in the modern pharmacological process due to their rich composition of secondary metabolites with significant biological activity. Computational tools are gaining momentum as they predict with higher accuracy, robust and provide insight in the interaction of small molecule with the disease target protein. This study was conducted for understanding the interaction mode of Phyto compounds with Env spike proteins of HIV. The compounds are studied for ADME properties and molecular docking using Schrödinger software was performed. From the results, Ethyl gallate was observed with least docking score and higher binding affinity for HIV-ENV protein (4CC8) and Cinnamyl acetate (cis/trans) with HIV-1-ENV protein (6ULC).