Two Unrecorded Species of the Snapper (Perciformes: Lutjanidae) Collected from Jeju Island, Korea

Maeng Jin Kim,Byung Yeob Kim,Joon Sang Kim,Choon Bok Song 한국수산과학회 2012 Fisheries and Aquatic Sciences Vol.15 No.4

Two unrecorded species of the snapper, Lutjanus malabaricus (296.0 mm standard length [SL]) and L. stellatus (350.0 mm SL) belonging to the family Lutjanidae, were first collected from the western coastal waters of Jeju Island, Korea. L. malabaricus is characterized by having a dark marking on the upper half of the caudal peduncle, a band of vomerine teeth that does not protrude posteriorly at the middle, and nine anal soft rays. Compared to its Korean relative, L. malabaricus is distinguishable by having rows of scales that run obliquely in the dorsal-posterior direction above the lateral line (vs. parallel to the lateral line in L. argentimaculatus). L. stellatus can be identified by the absence of wavy blue lines on the head (vs. many blue lines in L. rivulatus) and presence of a white spot above the lateral line (vs. a black blotch on the lateral line in L. rivulatus). We propose new Korean names, Jin-hong-tung-dom” and “Huin-jeom-tung-dom,” for L. malabaricus and L. stellatus, respectively.

The Korean Society of Gastroenterology& SLDDS 2042 : Slide Session ; K-BP-32 : Pancreatobiliary ; Predictable Factors for Anomalous Union of Pancreaticobiliary Duct Related Pancreaticobiliary Malignancy

( Jin Seok Park ),( Tae Jun Song ),( Do Hyun Park ),( Sang Soo Lee ),( Dong Wan Seo ),( Sung Koo Lee ),( Myung Hwan Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: To determine appropriate treatment of anomalous union of pancreaticobiliary duct (AUPBD), evaluation of AUPBD-related pancreaticobiliary malignancies is essential. The aim of this study is to determine the incidence of AUPBD-related pancreaticobiliary malignancies and to propose their predictable factors. Methods: We retrospectively reviewed data from 229 patients with AUPBD between January 1999 and December 2013. The incidence of AUPBD-related pancreaticobiliary diseases according to the presence of bile duct dilatation and the predictable factors for pancreaticobiliary malignancies were evaluated. Results: Among 229 patients, 152 patients had AUPBD with bile duct dilatation (=10mm) (dilated group) and 77 patients had AUPBD without bile duct dilatation (<10mm) (non-dilated group). In non-dilated group, intrahepatic cholangiocarcinoma (non-dilated group vs. dilated group; 3.9%vs.0%, P value=0.014) and pancreatitis (10.4%vs.1.3%, P value=0.003) occurred more frequently than in dilated group. On the other hand, although extrahepatic cholangiocarcinoma tended to be more occurred in dilated group (1.3%vs.3.9%, P value=0.271), there were no signifi cant differences in most of pancreaticobiliary diseases between two groups, In univariate analysis to determine predictable factors for AUPBD-related pancreaticobiliary malignancies, age, type of AUPBD, and refi uxed pancreatic enzyme showed signifi cant differences. In multivariate analysis, the old age (Odd ratio, 1.042; 95% CI, 1.011-1.073; P value= 0.007), B-P type (Odd ratio, 3.327; 95% CI, 1.031-10.740; P value=0.044), and the high level of biliary lipase level (Odds ratio=4.132, CI=1.420-12.021, P value=0.009) showed a signifi cant association with AUPBD-related pancreaticobiliary malignancies. Conclusion: Age, type of AUPBD, and biliary lipase level are signifi cantly related to AUPBD-related pancreaticobiliary malignancies. As a result, bile duct resection with cholecystectomy might be considered as a primary treatment of AUPBD patients without bile duct dilatation, especially in patients with old age (=45 year), high level of biliary lipase (=45,000 IU/L), and/or B-P type of AUPBD.

Poster Session : PS 0848 ; Upper GI Tract : Synchronous Second Primary Cancers in Patients with Squamous Esophageal Cancer: Clinical Features and Survival Outcome

( Jin Seo Lee ),( Ji Yong Ahn ),( Jeong Hoon Lee ),( Do Hoon Kim ),( Kee Don Choi ),( Ho June Song ),( Yong Hee Kim ),( Gin Hyug Lee ),( Hwoon Yong Jung ),( Jin Sook Ryu ),( Sung Bae Kim ),( Jong Hoon 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: To evaluate clinical features and treatment outcome of patients with synchronous second primary cancers (SPC) detected at the initial staging of squamous esophageal cancer (EC). Methods: We identifi ed a total of 317 consecutive patients diagnosed with squamous EC. Relevant clinical and cancer-specifi c information were reviewed retrospectively. Results: EC patients with synchronous SPC were identified in 21 patients (6.6%). There were signifi cant differences in median age (70 vs. 63 years; p=0.01) and body mass index (20.4 vs. 22.8 kg/m²; p=0.01) between EC patients with and without SPC. Head and neck, lung and gastric cancers accounted for 18.2%, 22.7% and 18.2% of SPC, respectively. Positron emission tomography-computed tomography (PET-CT) detected 4 cases (18.2%) of SPC that were missed on CT. Management plans were altered in 13 of 21 patients (61.9%) with detected SPC. Curative esophagectomy was attempted in 28.6% of EC patients with SPC (vs. 59.1% of patients without SPC; p=0.006). EC patients with SPC demonstrated signifi cantly lower 5-year survival than patients without SPC (10.6% vs. 36.7%; p=0.008). Conclusions: Synchronous second primary cancers (SPC) were found in 6.6% of squamous EC patients and gastric cancer was one of the most common SPC. EC patients with SPC were older with a signifi cantly lower body mass index than patients without SPC. PET-CT contributed substantially to the detection of synchronous SPC. EC patients with SPC demonstrated dismal survival because of the diffi culties of stage-appropriate treatment.

Poster Session : PS 0773 ; Upper GI Tract : Endoscopic Resection for Gastric Subepithelial Tumors; Safety, Effi cacy and Limitations

( Jin Sung Lee ),( Gwang Ha Kim ),( Geun Am Song ),( Jeong Heo ),( Dong Uk Kim ),( Hyun Young Woo ),( Bong Eun Lee ),( Yae Su Jang ),( Byoung Gil Ha ),( Jong Hun Seo ),( Tae Wook Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Some gastric subepithelial tumors (SETs) have malignant potential. But, pathologic diagnosis is challenging. Recently, there are increasing reports about endoscopic resection applied to resect gastrointestinal SETs. We aimed to determine the effi cacy and safety of endoscopic resection for the removal of gastric SETs. Methods: From January 2006 to December 2013, 51 patients were included in this study. They underwent routine upper gastrointestinal endoscopy and endoscopic ultrasonography (EUS). endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) was used to remove gastric SETs. The results of complete resection rates and complications were analyzed. Results: The ratio of male to female was 18:33 (35.3%:64.7%), and the mean age was 55.6 ± 11.1 years. The median tumor size measured by EUS was 14.2 mm (range 4-80 mm), and the median procedure time was 25 minutes (range 6-140 minutes). En bloc resection was achieved in 44 cases (86.3%) and histologic complete resection (CR) was done in 42 (82.4%). Complete resection was considerably low when tumor originate from proper muscle layer (4/8, 50.0%) than submucosal layer (38/43, 88.4%, p=0.019). Histologic diagnosis was obtained in all cases, including 16 carcinoid tumors, 12 infl ammatory fi brinoid polyps, 6 gastrointestinal stromal tumors and 17 others. Signifi cant bleeding during procedure was occurred in three cases and delayed bleeding was occurred in one case. Perforation was detected in 2 cases. The mean follow-up period was 22 months and any recurrence was not identifi ed. Conclusions: Endoscopic resection is safe and effective method to resect and acquire a histologic diagnosis of gastric SETs. However, to achieve en bloc excision for completely curative aim, novel endoscopic procedure including endoscopic full-thickness resection or conventional surgical wedge resection would also be considered, when tumor originate from proper muscle layer.

Behavior of Currents and Suspended Sediments around a Silt Screen

Jin, Jae-Youll,Chae, Jang-Won,Song, Won-Oh,Park, Jin-Soon,Kim, Sung-Eun,Jeong, Weon-Mu,Yum, Ki-Dai,Oh, Jae-Kyung Korea Institute of Ocean ScienceTechnology 2003 Ocean and Polar Research Vol.25 No.suppl3

The behavior of Suspended Sediment Concentrations (SSC) around a silt screen in a microtidal coastal area was hydrodynamically measured. The current speed at the mid-layer about 30m downstream of the screen reduces to about half that at the same distance upstream. It was caused by the contraction of the vertical section due to the screen. Even during a relatively weak storm period the SSC increases to that of the value caused by dredging. Section-averaged SSC at the downstream of the screen is higher by about 60% than that at the upstream, suggesting that the silt screen plays an adverse effect rather than a constructive role in the reduction of SSC generated by dredging.

Assessment of cervical cancer screening policy in women aged older than 65 years in Korea

( Sang Hoon Lee ),( Ye Won Chung ),( Jin Hwa Hong ),( Jae Kwan Lee ),( Nak Woo Lee ),( Jae Yun Song ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

Updated US guidelines recommend that women aged older than 65 years with evidence of adequate negative prior screening do not require cervical cancer screening. There is no guideline about the appropriate timing and conditions to stop cervical cancer screening in Korea. The purpose of this study was to evaluate the value of cervical cancer screening test in women >65 and to assess the potential age of stopping screening in old women The data of 999 women who underwent cervical cancer screening test followed by coloposcopy at the University hospital from January 2007 to May 2012 were evaluated retrospectively. The mean age was 45.5±13.7 (range: 14-80). Age groups were classified as <21 (n=11), 21-29 (n=128), 30-65 (n=768), and >65 (n=92) and there was no difference in the pathologic results of 65. There was significant higher incidence of cancer compared with ≤CIN3 in women >65 (13.0%) vs. ≤65 (6.6%) (p=0.037). Subjects were further categorized into five age groups (≤55 vs >55, ≤60 vs >60, ≤65 vs >65, ≤70 vs >70, and ≤75 vs >75) to create a cutoff age in terms of the ≤CIN3 vs. cancer, which identified that the cancer incidence was different until the age of 65 but not age over 70. Cervical cancer screening is necessary in women > 65 due to the higher incidence of cervical cancer compared with ≤CIN3. The ratio of higher incidence of cancer was disappeared at the age of 70. New guideline with the appropriate timing and conditions to stop screening should be considered in Korea.

Value of Early Referral for Sperm Cryopreservation in Young Men with Cancer

( Sang Hoon Lee ),( Yong Jin Kim ),( Kyong Wook Yi ),( Hyun Tae Park ),( Jae Yun Song ),( Sun Haeng Kim ),( Tak Kim ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

The purpose of this study was to determine the quality of sperm and to evaluate the value of early referral to reproductive specialists for sperm banking in young men with cancer. Data was included in cancer patients who underwent sperm cryopreservation for fertility preservation at the university hospital from April 1998 to October 2011. Secondary analysis of prospective database was performed to evaluate the sperm quality in cancer patients. Of the 51 patients with 92 freezing cycles, data was available in 45 patients with 85 cycles (mean age 27.1±7.3). Thirty three patients were referred before chemotherapy (PreCTX) and 12 were after chemotherapy (PostCTX). Of the 85 cycles, 95.3% (volume), 77.6% (motility), and 44.7% (count) were lower than the normal values for semen analysis. In the PreCTX, 14 had single sperm collection (SSC) and 14 had multiple collections (MSC). There was significant difference in the mean-time of referral in the SSC vs MSC (3.2±3.6 vs 21.2±26.0, p=0.02), Five out of 33 in the PreCTX had additional sperm collection after chemotherapy due to the lack of sperm quality and quantity. Three out of those were referred on the first day of chemotherapy. Patients who were referred 5 days before chemotherapy enable multiple collections. Early referral for sperm banking before chemotherapy should be considered as an essential factor for fertility preservation since the quality of sperm in cancer patients tends to be lower than normal patients, when appropriate, enables multiple fertility preservation cycles. This is the first study demonstrating the benefit of early referral for sperm banking in cancer patients.

Poster Session : PS 0750 ; Rheumatology ; Application of the 2013 ACR/EULAR Classifi cation Criteria for Systemic Sclerosis to Patients with Raynaud`s Phenomenon

( Jin Su Park ),( Min Chan Park ),( Jung Sik Song ),( Yong Beom Park ),( Soo Kon Lee ),( Sang Won Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: We investigated how many patients with Raynaud`s phenomenon (RP), but not systemic sclerosis (SSc) would be reclassifi ed as SSc, and we analyzed the predictive values for the reclassifi cation as SSc using the 2013 ACR/EULAR classifi cation criteria Methods: We consecutively enrolled 64 patients with RP and 60 patients with SSc. We applied the new classifi cation criteria to patients with RP, reclassifi ed them, and compared variables between those who were newly reclassifi ed as SSc and those who were not or previously diagnosed as SSc. The predictive values for the reclassifi cation as SSc were also assessed. Results: Seventeen of 64 patients (26. 5%) with RP were newly classifi ed as SSc according to the 2013 ACR/EULAR classifi cation criteria. Patients newly classifi ed as SSc had sclerodactyly, digital tip ulcer, telangiectasia, abnormal nailfold capillaries and the presence of anti-centromere antibody more frequently than those not. The independent predictive values for the reclassifi cation as SSc were sclerodactyly (OR 60. 025),telangiectasia (OR 13. 353) and the presence of anti-centromere antibody (OR 11. 168). Telangiectasia and anti-centromere antibody in newly classifi ed patients were more frequently than those in previously diagnosed SSc patients. Conclusions: 26. 5% of patients with RP were newly classifi ed as SSc by the 2013 ACR/EULAR classifi cation criteria, and sclerodactyly, telangiectasia, and the presence of anti-centromere antibody were the independent predictive values for the reclassifi - cation as SSc.

Changes in serum uric acid levels after allogeneic hematologic stem cell transplantation: A retrospective cohort study

Sang Hyun Joo,Jin Kyun Park,Eunyoung Emily Lee,Yeong Wook Song,Sung-Soo Yoon 대한혈액학회 2016 Blood Research Vol.51 No.3

BackgroundSince cell turnover in the hematopoietic system constitutes a major source of uric acid (UA) production, we investigated whether hematopoietic stem cell transplantation (HSCT) is associated with significant changes in serum UA levels in patients with hemato-logical disorders. MethodsPatients who underwent HSCT at our institution between 2001 and 2012 were retro-spectively enrolled. Serum UA levels at 3 months before, 1 week before, and 3 months and 1 year after HSCT were examined. ResultsComplete clinical and laboratory information including data regarding UA levels was avail-able for 93 patients. At baseline, the mean UA level was 4.9±2.1 mg/dL, with an overall prevalence of hyperuricemia of 15% (defined as serum UA>6.8 mg/dL). Mean UA levels tended to be higher in patients with acute myeloid leukemia (4.8±2.0 mg/dL) and non-Hodgkin lymphoma (5.1±2.3 mg/dL) and lower in patients with aplastic anemia (mean, 4.2±1.8 mg/dL). UA levels dropped during myeloablative conditioning, reaching a nadir on the day of HSCT (3.27±1.4 mg/dL). Over the 3 months following HSCT, UA levels rose sharply (5.0±2.1 mg/dL) and remained stable up to 1 year after HSCT (5.5±1.6mg/dL). UA levels in HSCT recipients at 12 months correlated with those of their respective graft donors (Pearson r=0.406, P=0.001).ConclusionHSCT is associated with significant changes in uric acid levels in patients with hematologic disorders.

Slide Session : OS-NEP-10 ; Nephrology : The Association Between the Bacterial Colonization in Tunneled Cuffed Dialysis Catheter and Residual Renal Function

( Jin Suk Kang ),( Byeong Yun Young ),( Dong Won Lee ),( Sang Heon Song ),( Eun Young Seong ),( Soo Bong Lee ),( Ihm Soo Kwak ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Hemodialysis (HD) patients have compromised immunity that permits bacterial colonization and chronic low grade infection. There are few reports about the bacterial colonization of dialysis access which is one of the main passages of infection. We studied the association between bacterial colonization in tunneled cuffed dialysis catheter (TCC) and clinical factors, especially residual renal function and mortality. Methods: In this Retrospective study, we found the clinical data of 155 patients who received TCC removal from Jan. 2005 to Dec. 2012. Baseline data were collected from medical records. The follow-up data including urine output (UO), time of anuria and death were acquired from the patients or their family members by telephone. Results: In the analysis of biochemical parameters, there was no signifi cant difference between colonization group (26 patients, 16.8%) and non-colonization group (129 patients, 83.2%). Eighty six patients were followed up by telephone questionnaire and 21 (24%) of them belonged to the colonization group. The monthly rate of decrease in UO was signifi cantly more rapid in the colonization group (68.1 ± 75.2 vs. 32.9 ± 42.6 mL/min/month, p=0.012) and the time to anuria was also shorter in the colonization group (19.3 ± 18.9 vs. 48.6 ± 46.1 months, p=0.011). The survival analysis showed that the colonization group had significantly worse estimated anuria-free survival than non-colonization group (log rank p=0.001). The all-cause mortality, however, did not signifi cantly differ between the groups (log rank p=0.185). Conclusions: Bacterial colonization in TCC was associated with rapid loss of residual renal function.