http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Roh, Sang-Gun,Lee, Hong-Gu,Phung, Long Thang,Hidari, Hisashi Asian Australasian Association of Animal Productio 2002 Animal Bioscience Vol.15 No.5
Growth hormone-releasing peptide-2 (GHRP-2, also named KP102) is a new hexapeptide of a series of synthetic growth hormone-releasing peptides (GHRPs) which stimulates the secretion of growth hormone (GH) in vitro and in vivo in several species including calf, sheep and pig. The GH-releasing activity of GHRP-2 is two to three times more effective than that of the original GHRP-6, and GHRP-1 in the rats and humans. To date, GHRP-2 seems to be the most potent member of the family of GHRPs. Since the GHRPs are short peptides (5-7 amino acid residues), they are synthesized easily and are not as readily degraded in plasma as GHreleasing hormone (GHRH). These features ameliorate their potential on domestic animals because of their chemical nature the GHRPs are efficacious when administered i.v. orally or orally. However, studies in cow, pig and sheep do not indicate such a close relationship between GHRH, somatostatin (SS) and GH, calling into question the general applicability of the human and rat models. Perhaps there is an important role for an endogenous GHRP in the regulation of GH secretion in domestic animals. This review provides an overview on the current knowledge of physiological role of GHRP-2 in domestic animals.
Physiological Roles of Adipokines, Hepatokines, and Myokines in Ruminants
Roh, Sang-Gun,Suzuki, Yutaka,Gotoh, Takafumi,Tatsumi, Ryuichi,Katoh, Kazuo Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.1
Since the discovery of leptin secreted from adipocytes, specialized tissues and cells have been found that secrete the several peptides (or cytokines) that are characterized to negatively and positively regulate the metabolic process. Different types of adipokines, hepatokines, and myokines, which act as cytokines, are secreted from adipose, liver, and muscle tissue, respectively, and have been identified and examined for their physiological roles in humans and disease in animal models. Recently, various studies of these cytokines have been conducted in ruminants, including dairy cattle, beef cattle, sheep, and goat. Interestingly, a few cytokines from these tissues in ruminants play an important role in the post-parturition, lactation, and fattening (marbling) periods. Thus, understanding these hormones is important for improving nutritional management in dairy cows and beef cattle. However, to our knowledge, there have been no reviews of the characteristics of these cytokines in beef and dairy products in ruminants. In particular, lipid and glucose metabolism in adipose tissue, liver tissue, and muscle tissue are very important for energy storage, production, and synthesis, which are regulated by these cytokines in ruminant production. In this review, we summarize the physiological roles of adipokines, hepatokines, and myokines in ruminants. This discussion provides a foundation for understanding the role of cytokines in animal production of ruminants.
Roh, Dong Kyu,Ahn, Sung Hoon,Seo, Jin Ah,Shul, Yong Gun,Kim, Jong Hak Wiley Subscription Services, Inc., A Wiley Company 2010 Journal of polymer science. Part B, Polymer physic Vol.48 No.10
<P>A novel graft copolymer consisting of a poly(vinylidene fluoride-co-chlorotrifluoroethylene) backbone and poly(glycidyl methacrylate) side chains, that is, P(VDF-co-CTFE)-g-PGMA, was synthesized through atom transfer radical polymerization (ATRP) using CTFE units as a macroinitiator. Successful synthesis and microphase-separated structure of the polymer were confirmed by <SUP>1</SUP>H NMR, FTIR spectroscopy, and TEM. As-synthesized P(VDF-co-CTFE)-g-PGMA copolymer was sulfonated by sodium bisulfite, followed by thermal crosslinking with sulfosuccinic acid (SA) via the esterification to produce grafted/crosslinked polymer electrolyte membranes. The IEC values continuously increased with increasing SA content but water uptake increased with SA content up to 10 wt %, above which it decreased again as a result of competitive effect between crosslinking and hydrophilicity of membranes. At 20 wt % of SA content, the proton conductivity reached 0.057 and 0.11 S/cm at 20 and 80 °C, respectively. The grafted/crosslinked P(VDF-co-CTFE)-g-PGMA/SA membranes exhibited good mechanical properties (>400 MPa of Young's modulus) and high thermal stability (up to 300 °C), as determined by a universal testing machine (UTM) and TGA, respectively. © 2010 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 48: 1110–1117, 2010</P>
( Dongyoung Roh ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Hyunju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-b 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Melanoacanthoma (MA) is considered to be heavily pigmented variant of seborrheic keratosis. Owing to their pigmentation, MA may mimic the clinical appearance of malignant melanoma (MM). However, the dermoscopic patterns of MAs and MA-like MMs have rarely been compared yet. Objectives: To find the clinical and dermoscopic difference between MA and MA-like MM Methods: This study included 77 MA and 33 MA-like MM patients. We reviewed medical records, clinical and dermoscopic findings of the two groups retrospectively. Results: Crypt and comedo-like opening (70.4%) in MAs and blue-white veil (60.6%) in MMs were the most common dermoscopic findings respectively. Crypt, comedo-like opening, milia-like cyst, fissure, and hairpin vessel appeared more frequently in MA (p<0.05). On the other hand, atypical pigment network, blue-white veil, pseudopod and streak, atypical vessel, and base pigmentation presented more in MM (p<0.05). MAs quite often showed melanoma specific dermoscopic findings, especially blue-white veil (22.1%). Also, fissure (42.4%), crypt (21.2%), and comedo-like opening (15.2%) were observed in MMs, although they were typically benign pattern. Conclusion: Different dermoscopic patterns between two groups might be important clues of differential diagnosis in clinically MA-like lesions. However, we should be aware that melanoma specific dermoscopic patterns could be observed quite often in MA.
( Dongyoung Roh ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Hyunju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-b 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Dermoscopic patterns of acral melanocytic nevi (AMNs) are crucial in differentiation from acral melanoma. Despite several studies regarding dermoscopic patterns of acquired acral melanocytic nevi (AAMNs), those of congenital acral melanocytic nevi (CAMNs) have rarely been reported. Objectives: This study is purposed to compare the clinical and dermoscopic features between CAMNs and AAMNs. Methods: This study included 44 CAMN and 40 AAMN patients. We reviewed medical records, clinical and dermoscopic findings of the two groups retrospectively. Results: CAMNs were more asymmetric than AAMNs (P=0.002) and presented more frequently as a comma shape (P=0.005). Regarding dermoscopic findings, globular pattern (56.8%) was the most common feature in CAMNs, followed by parallel furrow (47.7%), and crista dotted (31.8%) pattern. In AAMNs, parallel furrow (47.5%) was the most common finding, followed by fibrillar (35%), and lattice-like (30%) pattern. Parallel ridge, fibrillar, globular, crista dotted and blue-white veil were statistically different between the both groups (p<0.05). Also, CAMNs showed melanoma specific dermoscopic patterns such as parallel ridge (20.5%) and blue- white veil (25%). Conclusion: In this study, dermoscopic patterns of CAMNs and AAMNs were quite different from each other. The result of this study could be helpful when encountering CAMNs. To our knowledge, dermoscopic patterns of CAMNs have not been studied in Korea.
Demographics and clinical features of trachyonychia: Korean bi-center study
( Dongyoung Roh ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: Although the trachyonychia is widely known nail disorder, demographics and clinical features were rarely been studied in Korean literature. Objectives: To investigate demographics and clinical features of trachyonychia patients Methods: We included 216 trachyonychia patients who visited Pusan National University Hospital (Busan and Yangsan) over a 16-year period (2003-2018). We reviewed medical records and clinical photographs retrospectively. Results: Sex ratio was 1 : 1.88 (M : F). Onset age showed double peak on 0~10 year-old group (17.6%) and 41~50 year-old group (26.9%). Housewife was the most common occupation (27%), followed by restaurant, bakery, and bar workers (19.5%), nursing or caregiver (8.2%), chemical or metal processor (7.5%) and clothing makers (6.3%). Associated nail diseases were observed in 7.4% of total patients (onychomycosis 4.6%, paronychia 2.3%). Concomitant dermatologic diseases were observed in 25.5% of total patients (hand/foot eczema 9.7%, alopecial areata 7.9%, psoriasis 3.2%). 34.3% felt itching sensation and 9.3% felt pain. Clinically, 37% showed opaque trachyonychia, 72.7% showed ragged cuticle and 30.6% showed periungual erythema. Conclusion: To our knowledge, dermographics and clinical features of trachyonychia have rarely been studied worldwidely including Korea. The result of this study could be helpful when encountering trachyonychia.
Clinical findings of onychophagia in Korean patients: a single centre experience
( Dongyoung Roh ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Hyunju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-b 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Onychophagia, defined as habitual nail biting, is a common disorder affecting 20~30% of the population. It can cause various changes of nail units. However, there have been no studies analyzing nail changes due to onychophagia. Objectives: To identify clinical characteristics of nail changes due to onychophagia in Korea Methods: This study included 36 onychophagia patients who visited Pusan National University Hospital (Busan and Yangsan) over a 15-year period (2002-2017). We reviewed medical records and clinical photographs retrospectively. Results: All ten finger nails were affected in 38.9% of patients. Left thumbnail was the most predominantly affected site (80.6%), followed by right thumbnail (75%). In clinical findings, nail bed shortening was the most common presentation (66.7%), followed by rough nail plate (47.2%), transverse groove (33.3%), brittle and splitting nail (25%), splinter hemorrhage (22.2%), longitudinal melanoychia (22.2%), wash-board nail (16.7%), and pterygium (5.6%). 83.3% of patients had periungual complication such as periungual exfoliation (69.4%), absent of ragged cuticle (58.3%), and paronychia (19.4%). Conclusion: To our knowledge, this study is the first study investigating clinical characteristics of onychophagia. The result of this study could be helpful when encountering onychophagia.