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      • KCI등재

        Role of Intra-seasonal Oscillations on Monsoon Floods and Droughts over India

        O. S. R. U. Bhanu Kumar,S. Ramalingeswara Rao,S. S. Raju,S. Ranganathan 한국기상학회 2010 Asia-Pacific Journal of Atmospheric Sciences Vol.46 No.1

        Aim of this diagnostic study is to investigate the impact of intra-seasonal oscillations in terms of number, duration and intensity on rainfall during June through September, 1979-2006. Analysis of wavelet spectra for winds at 850 hPa field for monsoon period reveals number and duration of oscillations, which exercise profound influence on monsoon rainfall. Results indicate that four to six oscillations appear in normal rainfall or flood cases, while two or three oscillations are identified in the years of drought episodes. Though total duration of above oscillations is varied from 25 to 85 days, the duration is short (20 to 35 days) obviously in the years of less number of oscillations and also the number of oscillations are directly related to the monsoon rainfall. The coefficient of correlation between them is 0.56, which is significant at 1% level. To examine the strength of intra-seasonal oscillations in terms of different indices on seasonal rainfall is investigated. The Madden and Julian Oscillation Index shows an inverse relationship with rainfall, where as a direct relationship is noticed between Monsoon Shear Index and rainfall for the study period. Both results are significant at 5% level. To consolidate the above statistical relationships, seasonal circulation changes in the contrasting years of monsoon rainfall have been examined; present study reveals that anomaly negative outgoing longwave radiation is noticed over most of Arabian Sea, Indian sub-continent and the Bay of Bengal during June through September in flood year (1988). But opposite convective activity is true in drought year (2002). Similarly the spatial U-850 hPa field distribution showed much stronger monsoon winds in 1988, while zonal circulation was very weak in 2002. Such differences are observed in the anomaly zonal wind field at 200 hPa also. Over the monsoon region U-850 hPa field is almost a mirror image of U-200 hPa distribution of wind field. Finally annual cycles of U-850 and U-200 hPa fields reflect striking difference at 200 hPa level during the summer monsoon period in flood and drought years.

      • Quest for Missing Proteins: Update 2015 on Chromosome-Centric Human Proteome Project

        Horvatovich, Pé,ter,Lundberg, Emma K.,Chen, Yu-Ju,Sung, Ting-Yi,He, Fuchu,Nice, Edouard C.,Goode, Robert J.,Yu, Simon,Ranganathan, Shoba,Baker, Mark S.,Domont, Gilberto B.,Velasquez, Erika,Li, D American Chemical Society 2015 Journal of Proteome Research Vol.14 No.9

        <P>This paper summarizes the recent activities of the Chromosome-Centric Human Proteome Project (C-HPP) consortium, which develops new technologies to identify yet-to-be annotated proteins (termed “missing proteins”) in biological samples that lack sufficient experimental evidence at the protein level for confident protein identification. The C-HPP also aims to identify new protein forms that may be caused by genetic variability, post-translational modifications, and alternative splicing. Proteogenomic data integration forms the basis of the C-HPP’s activities; therefore, we have summarized some of the key approaches and their roles in the project. We present new analytical technologies that improve the chemical space and lower detection limits coupled to bioinformatics tools and some publicly available resources that can be used to improve data analysis or support the development of analytical assays. Most of this paper’s content has been compiled from posters, slides, and discussions presented in the series of C-HPP workshops held during 2014. All data (posters, presentations) used are available at the C-HPP Wiki (<uri xlink:href='http://c-hpp.webhosting.rug.nl/' xlink:type='simple'>http://c-hpp.webhosting.rug.nl/</uri>) and in the Supporting Information.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jprobs/2015/jprobs.2015.14.issue-9/pr5013009/production/images/medium/pr-2014-013009_0005.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/pr5013009'>ACS Electronic Supporting Info</A></P>

      • Pre-sodiated nickel cobaltite for high-performance sodium-ion capacitors

        Yang, D.,Sun, X.,Lim, K.,Ranganathan Gaddam, R.,Ashok Kumar, N.,Kang, K.,Zhao, X.S. Elsevier Sequoia 2017 Journal of Power Sources Vol.362 No.-

        Sodium-ion capacitors (NICs) are a hybrid energy storage system that store energy via both charge adsorption at the cathode/electrolyte interface and charge intercalation in the bulk of the anode, thereby possessing a higher energy density than supercapacitors and a higher power density than batteries. In this work, nickel cobaltite (NiCo<SUB>2</SUB>O<SUB>4</SUB>) hollow spheres with a chestnut shell morphology have been solvothermally synthesized and tested in a sodium half-cell. The NiCo<SUB>2</SUB>O<SUB>4</SUB> material exhibits a reversible capacity of 313 mAh g<SUP>-1</SUP> at 1 A g<SUP>-1</SUP>. Pre-sodiation of NiCo<SUB>2</SUB>O<SUB>4</SUB> is found to significantly improve its energy density. A NIC fabricated with pre-sodiated NiCo<SUB>2</SUB>O<SUB>4</SUB> as the anode and an activated carbon (AC) as the cathode delivers an energy density of 60 Wh kg<SUP>-1</SUP> at the power density of 10,000 W kg<SUP>-1</SUP>. Ex-situ X-ray diffraction (XRD) and transmission electron microscopy (TEM) results reveal that NiCo<SUB>2</SUB>O<SUB>4</SUB> is converted to metallic nickel and cobalt and Na<SUB>2</SUB>O phases during the pre-sodiation. The metallic nickel and cobalt phases are kinetically favourable for the electrolyte diffusion and electrochemical reactions, thus significantly improving the performance of the pre-sodiated NiCo<SUB>2</SUB>O<SUB>4</SUB> electrode.

      • KCI등재

        Inhibition of Microbial Quorum Sensing Mediated Virulence Factors by Pestalotiopsis sydowiana

        Paramanantham Parasuraman,B Devadatha,V. Venkateswara Sarma,Sampathkumar Ranganathan,Dinakara Rao Ampasala,Dhanasekhar Reddy,Ranjith Kumavath,김인원,Sanjay K. S. Patel,Vipin Chandra Kalia,이정걸,Busi Siddha 한국미생물·생명공학회 2020 Journal of microbiology and biotechnology Vol.30 No.4

        Quorum sensing (QS)-mediated infections cause severe diseases in human beings. The control of infectious diseases by inhibiting QS using antipathogenic drugs is a promising approach as antibiotics are proving inefficient in treating these diseases. Marine fungal (Pestalotiopsis sydowiana PPR) extract was found to possess effective antipathogenic characteristics. The minimum inhibitory concentration (MIC) of the fungal extract against test pathogen Pseudomonas aeruginosa PAO1 was 1,000 μg/ml. Sub-MIC concentrations (250 and 500 μg/ml) of fungal extract reduced QSregulated virulence phenotypes such as the production of pyocyanin, chitinase, protease, elastase, and staphylolytic activity in P. aeruginosa PAO1 by 84.15%, 73.15%, 67.37%, 62.37%, and 33.65%, respectively. Moreover, it also reduced the production of exopolysaccharides (74.99%), rhamnolipids (68.01%), and alginate (54.98%), and inhibited the biofilm formation of the bacteria by 90.54%. In silico analysis revealed that the metabolite of P. sydowiana PPR binds to the bacterial QS receptor proteins (LasR and RhlR) similar to their respective natural signaling molecules. Cyclo(- Leu-Pro) (CLP) and 4-Hydroxyphenylacetamide (4-HPA) were identified as potent bioactive compounds among the metabolites of P. sydowiana PPR using in silico approaches. The MIC values of CLP and 4-HPA against P. aeruginosa PAO1 were determined as 250 and 125 μg/ml, respectively. All the antivirulence assays were conducted at sub-MIC concentrations of CLP (125 μg/ml) and 4-HPA (62.5 μg/ml), which resulted in marked reduction in all the investigated virulence factors. This was further supported by gene expression studies. The findings suggest that the metabolites of P. sydowiana PPR can be employed as promising QS inhibitors that target pathogenic bacteria.

      • SCIESCOPUSKCI등재

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