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      • KCI등재후보

        Mental-Health and A.I. -A Paradigm of Human Mechanisation

        ( Aditya Nayak ) 중앙대학교 인문콘텐츠연구소 2020 인공지능인문학연구 Vol.6 No.-

        This paper analyses the reconfiguration of the relationship between technological apparatus and our mental lifeworld. Technological network apparatus, particularly algorithmic networks are absorbing large domains of our life into themselves. In the process, our sense of self-identity has become fragile. We keep feeling disoriented by the overload of technological acceleration in our life in form of messages, notifications, and new methods of algorithmic monitoring of our life. Our sensory perception of reality has been hegemonised by intelligent machines. In response, the mental-health discourse identifies new mental-illnesses and their treatment procedures. However, the mental-health discourse functions on certain underlying philosophical assumptions which limit its ability to understand the contemporary real mental-problems faced by human beings. It gets trapped in its own logic. While claiming to bring the patient back into normality, it only traps humans further in the processes of human mechanisation. This paper highlights some of these issues and introspects new ways of understanding the current problem by going beyond the mental-health discourse.

      • KCI등재

        A Critical Aspect of Bioreactor Designing and Its Application for the Generation of Tissue Engineered Construct: Emphasis on Clinical Translation of Bioreactor

        Aditya Anand,Sarada Prasanna Mallick,Bhisham Narayan Singh,Shikha Kumari,Dheerendra Kumar Suman,Satyavrat Tripathi,Divakar Singh,Pradeep Srivastava 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.4

        Usage of bioreactors in the field of tissue engineering has played a significant role in enabling a controlled and reproducible change in the formation of damaged tissue on being provided with specific factors. Owing to the scarcity seen in providing sufficient donor organs for transplantation there is a huge requirement for large-scale production of artificial organs. This cannot be achieved by static culturing since it does not provide an invivo three-dimensional (3D) microenvironment therefore tissue engineering plays a vital role in the development of artificial tissues and organs as per the clinical demands whereas bioreactors have served a major role in providing the artificial microenvironment required by the cells to grow further into a tissue and then into an organ. By providing the specific biochemical cues and mechanoresponsive stimuli the bioreactors turn to be very effective in generating transplantable organs. Apart from performing studies in a controlled manner aimed at understanding biological and physicochemical effects, bioreactors also ensure the safe and reproducible production of tissueengineered constructs to achieve cost-effective large-scale production. The design criteria for bioreactors to be used in tissue engineering include optimal aspect ratio, proper aeration for the cells to proliferate, and agitation with reduced shear stress. The current review summarizes important aspects like Height/Diameter ratio or aspect ratio, shear stress, mechanical stress, aeration, agitation, oxygenation, etc. related to the design of tissue bioreactors, different types of bioreactors that are in use to date, and the reported pieces of literature to yield an overview on the existing concepts. It mainly focuses on the generation of 3D tissue constructs in various reactor systems specially designed for their culture and development along with their applications.

      • KCI등재

        Endoscopic Management of Post-Polypectomy Bleeding

        Aditya Gutta,Mark A. Gromski 대한소화기내시경학회 2020 Clinical Endoscopy Vol.53 No.3

        Post-polypectomy bleeding (PPB) is one of the most common complications of endoscopic polypectomy. There are multiple riskfactors related to patient and polyp characteristics that should be considered. In most cases, immediate PPB can be effectively managedendoscopically when recognized and managed promptly. Delayed PPB can manifest in a myriad of ways. In severe delayed PPB,resuscitation for hemodynamic stabilization should be prioritized, followed by endoscopic evaluation and therapy once the patientis stabilized. Future areas of research in PPB include the risks of direct oral anticoagulants and of specific electrosurgical settings forhot-snare polypectomy vs. cold-snare polypectomy, benefits of closure of post-polypectomy mucosal defects using through-the-scopeclips, and prospective comparative evaluation of newer hemostasis agents such as hemostatic spray powder and over-the-scope clips.

      • KCI등재

        Cellular Bucket Brigades with Worker Collaboration on U-Lines with Discrete Workstations

        Aditya Tirta Pratama,Katsuhiko Takahashi,Katsumi Morikawa,Keisuke Nagasawa,Daisuke Hirotani 대한산업공학회 2018 Industrial Engineeering & Management Systems Vol.17 No.3

        Cellular bucket brigades (CBB) are a new design of bucket brigade that can reduce unproductive travel by workers on U-shaped production lines. With CBB, each worker works on one side of an aisle when proceeding in one direction, and on the other side when proceeding in the reverse direction; workers then exchange their work when they meet each other. The throughput of CBB may be reduced due to blocking and/or halting at discrete workstations. A method for countering these blocking/halting conditions is proposed here; it utilizes worker collaboration such that a maximum of two workers can collaborate on the same task. The collaboration velocity is proportional to the sum of individual worker velocities, and is influenced by the worker collaboration coefficient. The existing model and its assumptions are utilized here to compare the performance of CBB against worker collaboration on a three-station, twoworker U-line for which the difference collaboration coefficient and work content of the product at each station are deterministic. The results show that worker collaboration almost always outperforms CBB, except for certain cases in which each worker has a different velocity at different stations.

      • Number of Levels, Arm Inductance and Modulation Trade-offs for High Power Medium Voltage Grid-Connected Modular Multilevel Converters

        Aditya Shekhar,Lucia Beloqui Larumbe,Thiago Batista Soeiro,Yang Wu,Pavol Bauer 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        There is an increasing focus on integrating flexible dc links for bulk power routing in medium voltage distribu-tion grids. In such applications, the ac-dc Modular Multilevel Converter (MMC) devised for medium voltage and high-power ratings can be an interesting choice. This paper highlights some less explored design trade-offs arising due to the limitation on N in relation to modulation frequency and arm inductance. Specifically, the study intends to describe the interdependent influence of each degree of freedom on several aspects such as capacitor voltage balancing, circulating currents and harmonic performance. Finally, the importance of considering interhar-monics in the performance assessment of the MMC instead of the conventional interpretation of distortion calculation is highlighted.

      • KCI등재

        Investigation of Corner Cracks in Continuous Casting Billet Using Thermomechanical Model and Plant Measurements

        Aditya Narayan Shiv Shankar Swain,Suvankar Ganguly,Arunava Sengupta,Elanjickal Zachariah Chacko,Swapnil Dhakate,Pankaj Kumar Pandey 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.10

        A coupled thermofluidic-mechanical model has been developed to analyse the thermomechanical state of the solidifying shellin a continuously cast steel billet. The computational fluid dynamics (CFD) based solver simulates the three-dimensionalflow field and solidification of molten steel as it flows inside the mould. Finite element method based thermomechanicalmodel is coupled with the CFD model to determine the resultant temperature distribution and stress–strain evolution in thesolidifying strand. The heat transfer at the mould-billet interface is taken into account by the calculation of heat flux using anovel inverse heat transfer algorithm. Temperature measurements made in the industrial billet mould have been used for thepurpose. Plant experiments and observations are correlated with the numerical results to provide quantitative understandingof the complex thermomechanical process during billet casting. Various parametric studies are also undertaken to examinethe effects of casting speed, superheat and heat flux changes on resultant strain and temperature distribution. It is observedthat the accumulated plastic strains exceed the critical strain at the off-corner region thereby indicating the possibility ofcrack formation in this region. Reduction of heat flux can lead to lowering of the strain rate at the corners and offer a viablesolution for reducing corner cracks.

      • KCI등재

        Development of acute kidney injury following pediatric cardiac surgery

        Aditya Sharma,Ronith Chakraborty,Katyayini Sharma,Sidharth K. Sethi,Rupesh Raina 대한신장학회 2020 Kidney Research and Clinical Practice Vol.39 No.3

        Acute kidney injury (AKI) in the pediatric population is a relatively common phenomenon. Specifically, AKI has been found in increasing numbers within the pediatric population following cardiac surgery, with up to 43% of pediatric patients developing AKI post-cardiac surgery. However, recent advances have allowed for the identification of risk factors. These can be divided into preoperative, intraoperative, and postoperative factors. Although the majority of pediatric patients developing AKI after cardiac surgery completely recover, this condition is associated with worse outcomes. These include fluid overload and increased mortality and result in longer hospital and intensive care unit stays. Detecting the presence of AKI has advanced; use of relatively novel biomarkers, including neutrophil gelatinase associated lipocalin, has shown promise in detecting more subtle changes in kidney function when compared to conventional methods. While a single, superior treatment has not been elucidated yet, novel functions of medications, including fenoldopam, theophylline and aminophylline, have been shown to have better outcomes for these patients. With the recent advances in identification of risk factors, outcomes, diagnosis, and management, the medical community can further explain the complexities of AKI in the pediatric population post-cardiac surgery

      • KCI등재

        The Use of Antibiotics in Hospice and Palliative Care Settings

        Aditya C. Shekhar 한국호스피스완화의료학회 2022 한국호스피스.완화의료학회지 Vol.25 No.1

        Antibiotics are commonly prescribed medications in the hospice and palliative care setting, as well as in many other healthcare settings. The overuse or negligent use of antibiotics is associated with the harmful consequence of fostering the development of antibioticresistant pathogens. Thus, there is an urgent need to critically examine and audit antibiotic use in all aspects of healthcare. In the status quo, there is a lack of consistent standards and guidelines surrounding the use of antibiotics in hospice and palliative care settings, leading to significant variations in how antibiotics are prescribed and administered in end-oflife care. It is apparent that greater thought needs to go into antibiotic decisions for patients receiving hospice or palliative care, especially considering the harmful consequences of the overprescription of antibiotics. The literature suggests that many clinicians prescribe antibiotics inappropriately for patients who would not benefit from their use or prescribe them without adequate documentation. Clinicians should be deliberate about when they prescribe antibiotics and adhere to the appropriate documentation standards and procedures within their institution or community. Future research should seek to generate generalizable knowledge about which patients will benefit most from antibiotic therapy during end-oflife care.

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