Study on Active Defense Technology and Detection Algorithm of Virus Based on Computer Network

Gao Rui 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.7

Computer network virus has been manufactured in bulk, which can affect the normal work and study of people, and therefore the defense and detection of computer network virus should be concerned, advanced defense ability of computer network virus under the environment of computer internet can be improved. Firstly, the basic characteristics of computer network virus are analyzed. Secondly, main computer network virus propagation models are studied. Thirdly, active defense technology and detection model of computer network virus are established based on supported vector machine, and corresponding algorithm procedure is constructed. Finally, the simulation experiments are carried out, and results show that the detection model can obtain better detection effect of the computer network virus.

Diabetes Mellitus Is Associated with Inferior Prognosis in Patients with Chronic Lymphocytic Leukemia: A Propensity Score-Matched Analysis

Rui Gao,Tian-Shuo Man,Jin-Hua Liang,Li Wang,Hua-Yuan Zhu,Wei Wu,Lei Fan,Jian-Yong Li,Tao Yang,Wei Xu 대한암학회 2020 Cancer Research and Treatment Vol.52 No.1

Purpose Diabetes mellitus (DM) is associated with elevated cancer risk and poor survival outcome in malignancies. The objective of this study was to evaluate the prognostic value of preexisting DM in chronic lymphocytic leukemia (CLL). Materials and Methods Six hundred and thirty-three subjects with newly-diagnosed CLL between 2007 and 2016 were recruited. Propensity score-matched method was performed to balance baseline characteristics and eliminate possible bias. Univariate and multivariate Cox regression analyses screened the independent risk indicators for time-to-first-treatment (TTFT) and cancer-specific survival (CSS) of CLL. Receiver operator characteristic curves and the corresponding areas under the curve assessed the predictive accuracy of CLL–International Prognostic Index (IPI) together with DM. Results The results showed that 111 patients had pre-existing DM. In the propensity-matched cohort, DM was correlated with inferior TTFT and CSS in CLL patients, and it was an independent prognostic factor for both CSS and TTFT. Pre-diabetics also shared undesirable prognostic outcome compared with patients with no diabetic tendency, and a positive association between longer diabetic duration and poorer prognosis of CLL was identified. DM as one additional point to CLL-IPI had larger area under the curve compared with CLLIPI alone in CSS prediction and could improve the prognostic capacity of CLL-IPI. Conclusion Pre-existing DM was found to be a valuable prognostic predictor and could help predict life expectancy and build refined prognostication models for CLL.

Performance and Spatial Succession of a Full-Scale Anaerobic Plant Treating High-Concentration Cassava Bioethanol Wastewater

( Gao Rui Fang ),( Xu Feng Yuan ),( Jia Jia Li ),( Xiao Fen Wang ),( Xu Cheng ),( Wan Bin Zhu ),( Zong Jun Cui ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.8

A novel two-phase anaerobic treatment technology was developed to treat high-concentration organic cassava bioethanol wastewater. The start-up process and contribution of organics (COD, total nitrogen, and NH4+-N) removal in spatial succession of the whole process and spatial microbial diversity changing when sampling were analyzed. The results of the start-up phase showed that the organic loading rate could reach up to 10 kg COD/m3d, with the COD removal rate remaining over 90% after 25 days. The sample results indicated that the contribution of COD removal in the pre-anaerobic and anaerobic phases was 40% and 60%, respectively, with the highest efficiency of 98.5%; TN and NH4+-N had decreased to 0.05 g/l and 0.90 g/l, respectively, and the mineralization rate of total nitrogen was 94.8%, 76.56% of which was attributed to the anaerobic part. The microbial diversity changed remarkably among different sample points depending on the physiological characteristics of identified strains. Moraxellaceae, Planococcaceae, and Prevotellaceae were dominant in the pre-anaerobic phase and Bacteroidetes, Campylobacterales, Acinetobacter, Lactobacillus, Clostridium, and Bacillus for the anaerobic phase. Methanosarcinaceae and Methanosaeta were the two main phylotypes in the anaerobic reactor.

Experimental investigation of influence of scratch features on GaAs cleavage plane during cleavage processing using a scratching capability index

Rui Gao,Chen Jiang,XiaoHu Lang,KangJia Dong,FuRong Li 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.3

High-power semiconductor laser cavities are formed via the cleavage plane, and critically influence the reliability and performance of the laser. This paper investigates both the scratching operation and the cleavage operation to improve the quality of the cleavage plane during the entire cleavage process. The scratching capability index (SCI) variable was proposed to evaluate the scratch quality of GaAs. A series of scratching and cleavage experiments were carried out to investigate the effect of the scratch features on the GaAs cleavage plane. Experimental results of the scratching operation showed that a smaller scratching load and higher scratching speed were beneficial for reducing the kerf width and damage area width of GaAs. The cleavage operation on GaAs {100} cleavage planes exhibited crack propagation in the [1̄01̄] and [1̄00] directions and a slip direction in the <110> crystal direction. The calculated SCI variable correlated well with the scratch and cleavage qualities of GaAs, where a higher scratching SCI correlated with a smoother GaAs cleavage plane during cleavage processing. Thus, the SCI has the potential to relate the scratching parameters with the resulting cleavage plane quality of GaAs, which will help improve the manufacturing of semiconductor laser chips in the future.

Low-Rank Representation-Based Image Super-Resolution Reconstruction with Edge-Preserving

( Rui Gao ),( Deqiang Cheng ),( Jie Yao ),( Liangliang Chen ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.9

Low-rank representation methods already achieve many applications in the image reconstruction. However, for high-gradient image patches with rich texture details and strong edge information, it is difficult to find sufficient similar patches. Existing low-rank representation methods usually destroy image critical details and fail to preserve edge structure. In order to promote the performance, a new representation-based image super-resolution reconstruction method is proposed, which combines gradient domain guided image filter with the structure-constrained low-rank representation so as to enhance image details as well as reveal the intrinsic structure of an input image. Firstly, we extract the gradient domain guided filter of each atom in high resolution dictionary in order to acquire high-frequency prior information. Secondly, this prior information is taken as a structure constraint and introduced into the low-rank representation framework to develop a new model so as to maintain the edges of reconstructed image. Thirdly, the approximate optimal solution of the model is solved through alternating direction method of multipliers. After that, experiments are performed and results show that the proposed algorithm has higher performances than conventional state-of-the-art algorithms in both quantitative and qualitative aspects.

Antibiotic resistance fate in the full-scale drinking water and municipal wastewater treatment processes: A review

Rui Gao,Minghao Sui 대한환경공학회 2021 Environmental Engineering Research Vol.26 No.4

Antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) have been widely identified as emerging pollutants in various aquatic compartments. Concerns have been raised that the antibiotic resistance determinants may occur in treated drinking water and wastewater, weakening the therapeutic efficacy of antibiotics and so posing threat to public health. Most often, laboratory trials are conducted to assess the removal efficiency of ARB and ARGs in individual treatment processes (e.g., disinfection). However, the random variations of microbial distribution and chemical compositions in real-world environments cannot be entirely simulated, presumably leading to false-positive results as a consequence. It is therefore useful to provide a summary of recent advancements regarding the antibiotic resistance attenuation during full-scale water/wastewater treatments, which has not been adequately evaluated so far. In this review, the prevalence, proliferation and transmission of ARB and ARGs in urban water cycle, coupled with corresponding detection methods are presented as a short overview. The fate of ARB and ARGs in the sequential drinking water and wastewater processing units is critically summarized, the aim of which is to provide guidance for improving the current water treatment facilities to further reduce the antibiotic resistance in finished water.

hARIP2 is a Putative Growth-promoting Factor Involved in Human Colon Tumorigenesis

Gao, Rui-Feng,Li, Zhan-Dong,Jiang, Jing,Yang, Li-Hua,Zhu, Ke-Tong,Lin, Rui-Xin,Li, Hao,Zhao, Quan,Zhang, Nai-Sheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Activin is a multifunctional growth and differentiation factor of the growth factor-beta (TGF-${\beta}$) superfamily, which inhibits the proliferation of colon cancer cells. It induces phosphorylation of intracellular signaling molecules (Smads) by interacting with its type I and type II receptors. Previous studies showed that human activin receptor-interacting protein 2 (hARIP2) can reduce activin signaling by interacting with activin type II receptors; however, the activity of hARIP2 in colon cancer has yet to be detailed. In vitro, overexpression of hARIP2 reduced activin-induced transcriptional activity and enhanced cell proliferation and colony formation in human colon cancer HCT8 cells and SW620 cells. Also, hARIP2 promoted colon cancer cell apoptosis, suggesting that a vital role in the initial stage of colon carcinogenesis. In vivo, immunohistochemistry revealed that hARIP2 was expressed more frequently and much more intensely in malignant colon tissues than in controls. These results indicate that hARIP2 is involved in human colon tumorigenesis and could be a predictive maker for colon carcinoma aggressiveness.

欧美学生习得 “了” “着”“过”的两种特殊偏误现象

高?(Gao Rui) 계명대학교 국제학연구소 2015 국제학논총 Vol.23 No.-

The paper performs statistical analysis of bias phenomena of le, zhe and guo acquisition by European and American students based on The Chinese Interlanguage Corpus and found that there was bias phenomena of misusing aspect markers of le, zhe and guo by European and American students. Specifically, le can be mixed with both guo and zhe, while there is no misuse between zhe and guo. The bias errors can be accounted for by both grammatical and pragmatic factors, while pragmatic factors play a major role in errors of misusing le and zhe.

A sigma class glutathione S-transferase gene regulated by the CncC pathway is required for phytochemical tolerance in the red flour beetle, Tribolium castaneum

Gao Shan-shan,Li Dong-yu,Huo Zhuang-kun,Zhang Yong-lei,Cao Yi-zhuo,Tan Yue-yao,Guo Xin-long,Zhang Jia-hao,Zhang Kun-peng,Li Rui-min 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.4

Insect glutathione S-transferases (GSTs) play a crucial role in the detoxification of exogenous compounds, especially insecticides and plant allelochemicals. A sigma class GST gene, TcGSTS7, mediates the response to eugenol in Tribolium castaneum. However, the mechanism underlying this effect remains largely unknown. In this study, TcGSTS7, which exhibits a structural motif and domain organization characteristic of GSTs, was cloned from the T. castaneum genome. Spatiotemporal expression analysis revealed that TcGSTS7 was most highly expressed at the late larva stage and was mainly expressed in the fat body and epidermis of larvae and adults, suggesting that TcGSTS7 may play a potential role in the protection against toxic xenobiotics in T. castaneum. Furthermore, the expression of TcGSTS7 was significantly induced after exposure to eugenol, while RNA inter ference (RNAi) targeting TcGSTS7 enhanced the sensitivity of the beetle to eugenol, indicating that TcGSTS7 is involved in the tolerance of T. castaneum to this insecticide. Interestingly, the depletion of TcCncC, which encodes a transcription factor of the CncC pathway that has been associated with the regulation of detoxification-related genes in insects, led to a reduction in the TcGSTS7 transcript level following exposure to eugenol, which suggests that TcGSTS7 acts downstream of the CncC pathway. Combined, these results indicated that TcGSTS7 partici pates in the tolerance of T. castaneum to phytochemicals in a CncC pathway-dependent manner. These findings have implications for the development of novel drugs for use in pest control.

Minus-C odorant binding protein TcasOBP7G contributes to reproduction and defense against phytochemical in the red flour beetle, Tribolium castaneum

Gao Shanshan,Zhang Xinyi,Zhou Can,Zhang Guangyan,Zhang Yong-lei,Li Rui-min,Zhang Kun-peng 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.4

Insect odorant binding proteins (OBPs) paly an important role in the recognition and transmission signals. One odorant binding protein gene, TcasOBP7G, was significantly up-regulated after exposure to eucalyptol. Never theless, the causal role of TcasOBP7G in Tribolium castaneum is still unclear. Here, TcasOBP7G was cloned and characterized from T. castaneum, aligning with the typical characteristic of Minus-C OBPs. The analysis of gene expression profile showed that TcasOBP7G is highly expressed at late larval and adult stage, with particularly high expression levels in ovary and testis of adults, suggesting that TcasOBP7G might be associated with reproduction of T. castaneum. Furthermore, RNAi of TcasOBP7G led to a decrease in spawning, while the development of gonads was normal, suggesting that TcasOBP7G may medicate the reproduction of T. castaneum. Additionally, the mRNA level of TcasOBP7G was significantly increased after exposure to eucalyptol, and knockdown of TcasOBP7G resulted in an increased susceptibility of T. castaneum to eucalyptol, indicating that TcasOBP7G is associated with the tolerance of T. castaneum to eucalyptol. Altogether, these results indicate that TcasOBP7G is required for both reproduction and defense against phytochemical in T. castaneum. This study will provide a theoretical basis for the development of novel control strategies based on the olfaction of insects.