HYDROXYAPATITE를 이용한 전두부 성형술

백롱민,박재현,김진환,백세민,오갑성,정연철 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.5

The shape and contour of the upper third of the face is provided basically by the frontal bone. A relatively thin soft tissue coverage, which consists of the skin and frontalis muscle, readily shows subtle changes on the underlying frontal bone. The forehead represents the fortune of one's youth from the viewpoint of physignomy, and a broad forehead with minimal supraorbital bossing and round curvature is preferrd in the Orient. The forehead with a deficient, flat contour or asymmetry could be indicated for augmentation. The exact site and amount of augmentation are dicided preoperatively using clinical assessment, medical photographs, and cephalometric analysis. Hydroxyapatite(Pyrost), because of its nonresorbability, seems to have advantages over other alloplastic materials for forehead augmentation. From March 1989 to February 1992 forehead augmentation has been performed in 60 patients. Through a coronal incision, the dissection was carried over the periosteum to the supraorbital ridge and the lateral orbital rim. The subperiosteal pocket was made through a small incision, and was packed with Pyrost. When indicated, facial rhytidectomy, or reduction malar plasty was performed simultaneously. The result had been satisfactory and long lasting. There had been no implant shifting, infection, or bony erosion when examed from 1 year to 4 years after surgery.

사안면열의 임상 치험례(5례 보고)

함정욱,김진오,백롱민,오갑성,백세민 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.5

The oblique facial clefts, which include Tessier No. 3, 4, and 5 clefts, are a catastrophic facial anomaly. The direction they take may be (oro)naso-ocular or oro-ocular. Although oblique facial clefts had beep reported before, in 1823 Laroche was the first to differentiate between ordinary cleft lip or harelip and clefts of the cheek. All these clefts are rare, their incidence ranging from 0.75 to 5.4 per 1,000 common clefts and only one case was reported in the Korean literature. In general multiple operations are required for the reconstruction of these anomalies and the results in most cases are far from ideal. We have experienced 5 cases of oblique facial cleft with acceptable results.

Performance Analysis of a Toroid-Type HTS SMES Adopted for Frequency Stabilization

A-Rong Kim,Sang-Yong Kim,Kwang-Min Kim,Jin-Geun Kim,Seokho Kim,Minwon Park,In-Keun Yu,Sangjin Lee,Myung-Hwan Sohn,Hae-Jong Kim,Joon-Han Bae,Ki-Chul Seong IEEE 2011 IEEE transactions on applied superconductivity Vol.21 No.3

<P>Superconducting magnetic energy storage (SMES) can overcome fluctuations in frequency because of its fast response time in charging and discharging energy. To stabilize the fluctuations in frequency of wind power generation systems (WPGSs), HTS SMES systems should be connected to the terminal of the WPGSs. Ulleung Island's power network in Korea was modeled with a real-time digital simulator (RTDS) to demonstrate the effectiveness of SMES at stabilizing frequency. A toroid-type HTS SMES cooled by conduction cooling and a DC/DC chopper to charge and discharge current were fabricated for the experiment. The simulation results show the frequency stabilization effected by the HTS SMES system with its operational characteristics such as real time variation in current and temperature.</P>

Connection algorithm of Real Time Digital Simulator with HTS SMES for power quality improvement

A-Rong Kim(김아롱),Dae-Won Kim(김대원),Gyeong-Hun Kim(김경훈),Jin-Geun Kim(김진근),Minwon Park(박민원),In-Keun Yu(유인근),Kideok Sim(심기덕),SeockHo Kim(김석호),Ki-Chul Seong(성기철) 대한전기학회 2009 대한전기학회 학술대회 논문집 Vol.2009 No.7

Superconducting Magnetic Energy Storage (SMES) system is one of the key technologies to overcome the voltage sag, swell, interruption and frequency fluctuation by fast response speed of current charge and discharge. In order to evaluate the characteristics of over mega joule class grid connected High Temperature Superconducting (HTS) SMES system, the authors proposed an algorithm by which the SMES coil could be connected to the Real Time Digital Simulator (RTDS). Using the proposed algorithm, users can perform the simulation of voltage sag and frequency stabilization with a real SMES coil in real time and easily change the capacity of SMES system as much as they need. To demonstrate the algorithm, real charge and discharge circuit and active load were manufactured and experimented. The results show that the current from real system was well amplified and applied to the current source of simulation circuit in real time.

Design and Manufacturing of a SMES Model Coil for Real Time Digital Simulator Based Power Quality Enhancement Simulation

A-Rong Kim,Gyeong-Hun Kim,Kwang-Min Kim,Jin-Geun Kim,Dae-Won Kim,Minwon Park,In-Keun Yu,Seok-Ho Kim,Kideok Sim,Ki-Chul Seong IEEE 2010 IEEE transactions on applied superconductivity Vol.20 No.3

<P>The Superconducting Magnetic Energy Storage (SMES) system is a key technology for overcoming the voltage sag, swell, interruption, and frequency fluctuation with the fast response speed of current charge and discharge. A toroidal-type SMES is designed using a 3D CAD program, and the inductance and AC loss characteristic during operation are analysed using Finite Element Method (FEM) program. The toroidal-type magnet consists of 30 double pancake coils (DPC). The single pancake coils (SPC), constituting the double pancake coils, are arranged at an angle of 6° from each other, based on the central axis of the toroidal-type magnet. The conduction cooling method is used for the toroidal-type SMES cooling. To evaluate the characteristics of the over-mega-joule class grid-connected HTS SMES system, the authors implemented a simulation by which the SMES coil could be connected to the Real Time Digital Simulator (RTDS). Using the simulation, users can perform voltage sag and frequency stabilization simulations with a real SMES coil in real time and easily change the capacity of the SMES system as much as they need. The effectiveness of the toroidal-type HTS SMES system is demonstrated through the RTDS-based simulation and the results are briefly discussed.</P>

Responsive Surface Methodology Optimizes Extraction Conditions of Industrial by-products, <i>Camellia japonica</i> Seed Cake

Kim, Jae Kyeom,Lim, Ho-Jeong,Kim, Mi-So,Choi, Soo Jung,Kim, Mi-Jeong,Kim, Cho Rong,Shin, Dong-Hoon,Shin, Eui-Cheol Medknow PublicationsMedia Pvt Ltd 2016 Pharmacognosy magazine Vol.12 No.47

<P><B>Background:</B></P><P>The central nervous system is easily damaged by oxidative stress due to high oxygen consumption and poor defensive capacity. Hence, multiple studies have demonstrated that inhibiting oxidative stress-induced damage, through an antioxidant-rich diet, might be a reasonable approach to prevent neurodegenerative disease.</P><P><B>Objective:</B></P><P>In the present study, response surface methodology was utilized to optimize the extraction for neuro-protective constituents of <I>Camellia japonica</I> byproducts.</P><P><B>Materials and Methods:</B></P><P>Rat pheochromocytoma cells were used to evaluate protective potential of <I>Camellia japonica</I> byproducts.</P><P><B>Results:</B></P><P>Optimum conditions were 33.84 min, 75.24%, and 75.82°C for time, ethanol concentration and temperature. Further, we demonstrated that major organic acid contents were significantly impacted by the extraction conditions, which may explain varying magnitude of protective potential between fractions.</P><P><B>Conclusions:</B></P><P>Given the paucity of information in regards to defatted <I>C. japonica</I> seed cake and their health promoting potential, our results herein provide interesting preliminary data for utilization of this byproduct from oil processing in both academic and industrial applications.</P><P><B>SUMMARY</B></P><P><P>Neuro-protective potential of <I>C. japonica</I> seed cake on cell viability was affected by extraction conditions</P><P>Extraction conditions effectively influenced on active constituents of <I>C. japonica</I> seed cake</P><P>Biological activity of <I>C. japonica</I> seed cake was optimized by the responsive surface methodology.</P></P> >[FIG OMISSION]</BR><P><B>Abbreviations used:</B> GC-MS: Gas chromatography-mass spectrometer, MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, PC12 cells: Pheochromocytoma, RSM: Response surface methodology.</P>

Analyzed Model of The Active Filter combined with SMES

Kim A-Rong,Kim Jae-Ho,Kim Hae-Jong,Kim Seok-Ho,Seong Ki-Chul,Park Min-Won,Yu In-Keun The Korean Society of Superconductivity and Cryoge 2006 한국초전도저온공학회논문지 Vol.8 No.2

Recently, utility network is becoming more and more complicated and huge due to IT and OA devices. In addition to, demands of power conversion devices which have non-linear switching devices are getting more and more increased. Consequently, because of the non-linear power semiconductor devices, current harmonics are unavoidable. Sometimes those current harmonics flow back to utility network and become one of the main reasons which can make the voltage distortion. Also, it makes noise and heat loss. On the other hands, voltage sag from sudden increasing loads is also one of the terrible problems inside of utility network. In order to compensate the current harmonics and voltage sag problem, AF(active filter) systems could be a good solution method. SMES is a very good promising source due to it's high response time of charge and discharge. Therefore, the combined AF and SMES system can be a wonderful device to compensate both harmonics current and voltage sag. However, SMES needs a superconducting magnetic coil. Because of using this superconducting magnetic coil, quench problem caused by unexpected reasons have always been unavoidable. Therefore, to solve out mentioned above, this paper presents a decisive method using shunt and series active filter system combined with SMES. Especially, authors analyzed the change of original energy capacity of SMES regarding to the size of resistance caused by quench of superconducting magnetic coil.

Characterization of Nutritional Composition, Antioxidative Capacity, and Sensory Attributes of <i>Seomae</i> Mugwort, a Native Korean Variety of <i>Artemisia argyi</i> H. Lév. & Vaniot

Kim, Jae Kyeom,Shin, Eui-Cheol,Lim, Ho-Jeong,Choi, Soo Jung,Kim, Cho Rong,Suh, Soo Hwan,Kim, Chang-Ju,Park, Gwi Gun,Park, Cheung-Seog,Kim, Hye Kyung,Choi, Jong Hun,Song, Sang-Wook,Shin, Dong-Hoon Hindawi Publishing Corporation 2015 Journal of analytical methods in chemistry Vol.2015 No.-

<P>Few studies have investigated <I>Seomae</I> mugwort (a Korean native mugwort variety of <I>Artemisia argyi</I> H. Lév. & Vaniot), exclusively cultivated in the southern Korean peninsula, and the possibility of its use as a food resource. In the present study, we compared the nutritional and chemical properties as well as sensory attributes of <I>Seomae</I> mugwort and the commonly consumed species <I>Artemisia princeps</I> Pamp. In comparison with <I>A. princeps, Seomae</I> mugwort had higher contents of polyunsaturated fatty acids, total phenolic compounds, vitamin C, and essential amino acids. In addition, <I>Seomae</I> mugwort had better radical scavenging activity and more diverse volatile compounds than <I>A. princeps</I> as well as favorable sensory attributes when consumed as tea. Given that scant information is available regarding the <I>Seomae</I> mugwort and its biological, chemical, and sensory characteristics, the results herein may provide important characterization data for further industrial and research applications of this mugwort variety.</P>

Effects of Methoxsalen from <i>Poncirus trifoliata</i> on Acetylcholinesterase and Trimethyltin-Induced Learning and Memory Impairment

KIM, Jae Kyeom,CHOI, Soo Jung,BAE, Hyeri,KIM, Cho Rong,CHO, Hong-Yon,KIM, Young Jun,LIM, Seung Taik,KIM, Chang-Ju,KIM, Hye Kyung,PETERSON, Sabrina,SHIN, Dong Hoon Japan Society for Bioscience, Biotechnology, and A 2011 Bioscience, Biotechnology, and Biochemistry Vol.75 No.10

<P>Previously, we identified methoxsalen (8-methoxy-2′,3′,6,7-furocoumarin) as the bioactive compound probably responsible for acetylcholinesterase (AchE) inhibition achieved by feeding crude extract of <I>Poncirus trifoliate.</I> To confirm the activity of methoxsalen, Institute of Cancer Research (ICR) mice were fed a control or a methoxsalen-supplemented diet for 4 weeks, and then learning and memory enhancing effects with respect to trimethyltin (TMT)-induced neurotoxicity were evaluated. The brain tissues of ICR mice were dissected after completion of the behavioral tests for biochemical analysis. Methoxsalen effectively reversed TMT-induced memory impairment on both Y-maze and passive avoidance tests. Brain AchE activity was inhibited by the oral consumption of all concentrations of methoxsalen. Moreover, the level of oxidative stress was significantly ameliorated in the groups on methodsalen containing diets. This is the first <I>in vivo</I> study conducted with methoxsalen in the field of AD research, and it indicates that further investigation of methoxsalen is warranted.</P>

<i>Pyropia yezoensis</i> peptide promotes collagen synthesis by activating the TGF-β/Smad signaling pathway in the human dermal fibroblast cell line Hs27

Kim, Cho-Rong,Kim, Young-Min,Lee, Min-Kyeong,Kim, In-Hye,Choi, Youn-Hee,Nam, Taek-Jeong UNKNOWN 2017 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.39 No.1

<P><I>Pyropia yezoensis</I> (<I>P. yezoensis</I>) is a marine algae that exhibits antioxidant, anti-inflammatory, antitumor and anti-aging activities. In this study, we investigated the effects of the <I>P. yezoensis</I> peptide, PYP1-5, on collagen synthesis in the human dermal fibroblast cell line Hs27. Skin aging is related to reduced collagen production and the activities of multiple enzymes, including matrix metalloproteinases (MMPs), which degrade collagen structure in the dermis, and tissue inhibitor of tissue inhibitor of metalloproteinases (TIMPs), which inhibit the action of MMPs. While collagen synthesis is associated with a number of signaling pathways, we examined the increased collagen synthesis via the upregulation of the transforming growth factor-β (TGF-β)/Smad signaling pathway. Using MTS assay, we found that PYP1-5 did not affect cell viability. Moreover, we confirmed that PYP1-5 increased type 1 collagen expression using enzyme-linked immunosorbent assay (ELISA), western blot analysis and quantitative PCR. In addition, we identified changes in various enzymes, as well as the mechanisms behind the PYP1-5-induced collagen synthesis. PYP1-5 decreased the MMP-1 protein and mRNA levels, and increased the TIMP-1 and TIMP-2 protein and mRNA levels. In addition, PYP1-5 activated the TGF-β/Smad signaling pathway, which increased TGF-β1, p-Smad2 and p-Smad3 expression, while inhibiting Smad7, an inhibitor of the TGF-β/Smad pathway. Furthermore, PYP1-5 upregulated transcription factor specificity protein 1 (Sp1) expression, which is reportedly involved in type 1 collagen expression. These findings indicate that PYP1-5 activates the TGF-β/Smad signaling pathway, which subsequently induces collagen synthesis in Hs27 cells.</P>