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de Oliveira Letícia da S.,Fonseca Lucas P.,de Souza Renato D.,Bueno Cristina de F.,Martins Lucas M.,Scalvi Luis V.A. 한국물리학회 2022 Current Applied Physics Vol.41 No.-
Reduced graphene oxide (rGO) is deposited on glass substrate by dripping and sol-gel-coating methods giving rise to nanostructures. When in combination with thin films of SnO2, they form a heterostructure SnO2:2 at% Eu/ rGO, which alters the surface electrical conductivity. SnO2 and rGO were also combined as a composite, with conductivity strongly affected by ultraviolet excitation, and shows persistent photoconductivity (PPC) phenomenon even very close to room temperature. Both sort o hybrid structures can be applied in electronic devices. The SnO2 films are deposited via chemical route by sol-gel or by a mixed technique that combines powders generated by drying the sol-gel solution with resistive evaporation of this powder. Resistivity measured as a function of temperature show that the SnO2:2 at%Eu sample behaves very similarly to the SnO2:2 at%Eu/rGO heterostructure sample, with the same energy level for the dominant defect, 172 meV, coincident with ionization of oxygen vacancies. Despite not changing the position of this level, the presence of rGO on the surface of the SnO2 film induces a decrease in conductivity in vacuum, demonstrating the surface interaction.
Antinociceptive Activity of Aqueous Extract of Bowdichia virgilioides in Mice
Juliane P. Silva,Renato S. Rodarte,Andrea S. Calheiros,Cristiane Z. Souza,Fabio C. Amendoeira,Marco A. Martins,Patrı´cia Machado R. Silva,Valber S. Frutuoso,Emiliano Barreto 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.2
Bowdichia virgilioides Kunth (Family Fabaceae) is a plant that is distributed widely in the tropical and subtropical regions of the world. In the northeast region of Brazil, where B. virgilioides is called “sucupira-preta,” the stem bark is used in folk medicine to treatment of inflammatory and painful diseases. This study aimed to evaluate the antinociceptive activity of the aqueous extract of the dried stem bark of B. virgilioides. The aqueous extract of B. virgilioides in doses of 50, 100, 200, and 400mg/kg was administered orally 1 hour prior to pain induction. Only the doses of 200 and 400mg/kg produced an inhibition by 61% and 74%, respectively, in the number of abdominal writhings induced by acetic acid. This antinociceptive effect was not reversed by pretreatment with naloxone, indicating that the effect is not associated with the activation of opioid receptors. In the formalin test, using the two highest doses, the extract had no effect in the first phase but produced an analgesic effect on the second phase with the inhibition of licking time (P<.001). In the hot plate test, no effect was seen at the dose of 400mg/㎏ p.o. Our findings show that B. virgilioides contains pharmacologically active constituents that possess antinociceptive activity justifying its popular therapeutic use in treating conditions associated with the painful conditions.