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Active Speed Control of Belt Conveyor with Variable Speed Interval Based on Fuzzy Algorithm
Zhou Qixun,Gong Hao,Sun Wenhao,Yan Qi,Shi Keke,Du Guanghui 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.3
Aiming at the problems of too fast adjustment frequency, unstable material flling rate and fuctuation of material fow at the boundary of speed interval caused by unreasonable setting of speed interval in traditional active speed control strategy based on hierarchical speed regulation. An active speed control strategy based on fuzzy algorithm is proposed for belt conveyor. The material flling rate of the belt is taken as input, and the double-layer fuzzy boundary is set according to the expected value of the material flling rate to adjust the speed of the belt conveyor. The adjustment time of diferent speed intervals is given according to the estimation-calculation-optimization method. The simulation results of the double belt conveyor system show that compared with the active speed control strategy based on hierarchical speed regulation, the active speed control strategy can not only stabilize the material flling rate of the downstream belt conveyor near the expected value and improve the stability of transportation, but also reduce the energy by about 20.69% per hour on average. The subsequent experimental results also verify the efectiveness of the proposed active speed control strategy, which can achieve more sustainable operation of the belt conveyor.
Effect of plant secondary metabolites on common cutworm, Spodoptera litura (Lepidoptera: Noctuidae)
Qi Su,Zhixiong ZHOU,Jianmin ZHANG,Caihua SHI,Guohui ZHANG,Zhenyu JIN,Wenkai WANG,Chuanren LI 한국곤충학회 2018 Entomological Research Vol.48 No.1
The effect of various flavonoids, lectins and phenyl β‐D‐glucoside on larval survival, weights and the activities of digestive (total serine protease and trypsin) and detoxifying (esterase and glutathione‐S‐transferase) enzymes of Spodoptera litura larvae at 7 days after treatment was studied through diet incorporation assay. Flavonoids (rutin, chlorogenic acid, quinic acid, caffeic acid, naringenin, quercitin, kaempferol, myricetin, catechin, and ferulic acid) were incorporated in artificial diet at 100, 500 and 1000 ppm, lectins: groundnut leaf lectin (GLL), concavalin A (ConA) and phenyl β‐D‐glucoside at 1, 2 and 5 μg/mL. Flavonoids such as rutin, quercitin and kaempferol at 1000 ppm were more toxic to S. litura larvae than quinic acid, caffeic acid, naringenin, myricetin, catechin, and ferulic acid. Larval growth and development were significantly reduced in S. litura larvae fed on a diet with GLL and ConA at 5 μg/mL compared to the larvae fed at 2 and 1 μg/mL concentrations. The larvae fed on flavonoid‐treated diets showed significant reduction in serine protease, trypsin and esterase activities. The flavonoids such as rutin, chlorogenic acid, quinic acid, naringenin, quercitin, kaempferol and myricetin, and lectins, GLL and ConA can be utilized in insect control programs.
Lei Shi,Xiaolong Wang,Jinjia Wang,Ping Zhang,Fei Qi,Menghao Cai,Yuanxing Zhang,Xiangshan Zhou 한국유전학회 2018 Genes & Genomics Vol.40 No.4
Two catabolite repressor genes (MIG1 and MIG2) were previously identified in Pichia pastoris, and the derepression of alcohol oxidase (AOX) expression was realized in Δmig1 or Δmig1Δmig2 mutants grown in glycerol, but not in glucose. In this study, genome-wide RNA-seq analysis of Δmig1Δmig2 and the wild-type strain grown in glycerol revealed that the expression of numerous genes was greatly altered. Nearly 7% (357 genes) of approximately 5276 genes annotated in P. pastoris were significantly upregulated, with at least a two-fold differential expression in Δmig1Δmig2; the genes were mainly related to cell metabolism. Approximately 23% (1197 genes) were significantly downregulated; these were mainly correlated with the physiological characteristics of the cell. The methanol catabolism and peroxisome biogenesis pathways were remarkably enhanced, and the genes AOX1 and AOX2 were upregulated higher than 30-fold, which was consistent with the experimental results of AOX expression. The Mig proteins had a slight effect on autophagy when cells were grown in glycerol. The expression analysis of transcription factors showed that deletion of MIG1 and MIG2 significantly upregulated the binding of an essential transcription activator, Mit1p, with the AOX1 promoter, which suggested that Mig proteins might regulate the AOX1 promoter through the regulation of Mit1p. This work provides a reference for the further exploration of the methanol induction and catabolite repression mechanisms of AOX expression in methylotrophic yeasts.
Jun Zhou,Anyuan Fan,Cha Hyungki,Dong Liu,Dukhyeon Kim,Fudi Qi,Guangyu Shi,Guming Yue 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.1
A Mie lidar has been used to make observations of Asian dust over Hefei (31.90 N, 117.16 E) in the every spring month since the year of 1998. This paper presents the main features of the vertical distribution and the temporal variation of the Asian dust extinction coefficient at a 532-nm wavelength during seven years. There were two kinds of vertical distributions of Asian dust extinction coefficients. One kind of distribution indicated that the Asian dust particles intruded into the local boundary layer, causing a very thick dust layer with depth of about 3 4 km. The other one showed that the Asian dust passed over Hefei area above the boundary layer. The aerosol extinction coefficients in the elevated dust layer within the middle troposphere from 3 to 6 km were unusually large. Seasonally averaged aerosol extinction coefficient profiles showed that larger aerosol extinction coefficients were observed in the altitude range from 1 km to 10 km in the springtime than in any other season.쯢
The Mechanism of Rockbolt in the Jointed Rock Under Uniaxial Tension
Shen Zhou,Xiaoyu Ji,Li-Ping Li,Hong-liang Liu,Chun Zhu,Hongyun Fan,Qi Zhang,Caihua Shi,Xutong Zhang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.11
In this research, the rockbolt mechanism of a jointed rock mass under uniaxial tension was systematically revealed with a laboratory test and a numerical simulation. It was found that the rockbolt rock mass experienced five stages under uniaxial tension, the densification stage, elastic stage, plastic deformation stage, progressive debonding stage, and complete debonding stage. The stress-strain curve and ultimate tensile strength of a rockbolt rock mass were analyzed by taking the rockbolt spacing and rockbolt angle as variables. It was found that the improvement effect of the reduction of the rockbolt spacing on the ultimate tensile strength was limited. When the rockbolt spacing was reduced to a certain limit, the stress concentration area between adjacent rockbolts was connected and destroyed, resulting in the increase of the rockbolt rock strength becoming smaller, and even having a downward trend. The increase of the rockbolt angle led to the change of the stress mode and failure mode of the whole structure, and the ultimate tensile strength first increased and then decreased. The optimal rockbolt angle was between 60° and 70°. It is worth noting that there was an obvious mechanical occlusion between the thread on the rockbolt surface and the rock mass, resulting in the multi-stage step-down characteristic of the stress-strain curve in the complete debonding stage. The results of this study can provide a reference for the design and construction of similar projects.
Genetic Variation in PDCD6 and Susceptibility to Lung Cancer
He, Yan-Qi,Zhou, Bin,Shi, Shao-Qing,Zhang, Lin,Li, Wei-Min Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
Lung cancer is the most common type of cancer and one of the leading causes of death in the world. Genetic factors play an important role in its development. PDCD6, the encoding gene for programmed cell death protein 6, may function as a tumor suppressor gene. Non-small cell lung cancer (NSCLC) contributes about 80% to newly histologically diagnosed lung cancer patients. To explore the relationship between PDCD6 and NSCLC, we examined two single nucleotide polymorphisms(rs3756712 G/T andrs4957014 G/T, both in the intron region) of the PDCD6gene.A hospital-based case-control study was carried out including 302 unrelated NSCLC patients and 306 healthy unrelated subjects. Significantly increased NSCLC risk was found to be associated with the T allele of rs4957014 (P=0.027, OR=0.760, 95%CI=0.596-0.970). The genotype and allele frequencies of rs3756712 did not shown any significant difference between NSCLC group and controls (P=0.327, OR=0.879, 95%CI=0.679-1.137). In conclusion, we firstly demonstrated the association between the PDCD6 gene and risk of NSCLC in a Chinese Han population.
Chu, Jia-Qi,Jing, Kai-Peng,Gao, Xiang,Li, Peng,Huang, Rui,Niu, Yan-Ru,Yan, Shou-Quan,Kong, Jun-Chao,Yu, Cai-Yuan,Shi, Ge,Fan, Yi-Ming,Lee, Young-Ha,Zhou, Yu,Quan, Juan-Hua Landes Bioscience 2017 Cell Cycle Vol.16 No.5
<P>Autophagy and apoptosis are critical for controlling Toxoplasma gondii (T. gondii) infection. T. gondii infection during pregnancy can damage the fetus and cause birth defects; however, the molecular mechanisms of this process are poorly understood. This study aims to determine the activities of autophagy and apoptosis as well as their regulatory mechanisms during T. gondii infection by using human umbilical cord mesenchymal stem cells (hUC-MSCs) as a model of congenital diseases. LC3B, a hallmark protein of autophagy was incrementally upregulated with the infection duration, whereas p62 was downregulated in T. gondii-infected hUC-MSCs. Concurrent to this result, the invasion of T. gondii into hUC-MSCs increased in a time-dependent manner. The expression levels of Bcl-2 family proteins including Bcl-2, Bcl-xL, Bim, Bax, Bid and Bak were not altered; however, Mcl-1 levels in hUC-MSCs were dramatically decreased upon T. gondii infection. In addition, at 24h post-infection, cleaved PARP and cleaved caspase-3 protein levels were elevated in hUC-MSCs. Importantly, Mcl-1 overexpression reduced the levels of autophagy- and apoptosis-related proteins in T. gondii-infected hUC-MSCs. Mcl-1 proteins were primarily expressed in the fraction containing mitochondria and strongly interacted with Beclin-1 under normal conditions; however, these interactions were remarkably attenuated by T. gondii infection. These results suggest that mitochondrial Mcl-1 is an essential signaling mediator regulating the activation of autophagy and apoptosis during T. gondii infection.</P>
Risk Factors for Cervical Cancer in Rural Areas of Wuhan China: a Matched Case-control Study
Zhang, Bin,Zhou, Ai-Fen,Zhu, Chang-Cai,Zhang, Ling,Xiang, Bing,Chen, Zhong,Hu, Rong-Hua,Zhang, Ya-Qi,Qiu, Lin,Zhang, Yi-Ming,Xiong, Chao-Du,Du, Yu-Kai,Shi, Yu-Qin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12
Cervical cancer is a serious public health problem in developing countries. We investigated possible risk factors for cervical cancer in rural areas of Wuhan China using a matched case-control study with 33 women diagnosed with cervical cancer and 132 healthy women selected from the same area as matched controls. A questionnaire, which included questions about general demography conditions, environmental and genetic factors, the first sexual intercourse, first marriage age, age at first pregnancy, pregnancy first child's age, female personal health history, social psychological factors, dietary habits, smoking and alcohol status and other living habits was presented to all participants. At the same time, HPV infection of every participant was examined in laboratory testing. Results showed HPV infection (P<0.000, OR=23.4) and pregnancy first child's age (P<0.000, OR=13.1) to be risk factors for cervical cancer. Menopause (P=0.003, OR=0.073) was a protective factor against cervical cancer. However, there was no indication of associations of environmental (drinking water, insecticide, disinfectant) genetic (cancer family history), or life-style factors (smoking status, alcohol status, physical training, sleep quality), including dietary habits (intake of fruit and vegetable, meat, fried food, bean products and pickled food) or social psychological factors with cervical cancer. The results suggest that the risk of cervical cancer in Chinese rural women may be associated with HPV infection, menopause and the pregnancy first child's age.