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      • SCIESCOPUSKCI등재

        Effect of Feeding Time on Laying and Reproductive Performance of Pharaoh Quail (Coturnix coturnix Pharaoh) Housed in Different Cage Systems

        Petek, Metin Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.1

        A total of 120 male and 240 female quail (Coturnix coturnix Pharaoh) were used to determine the effect of feeding time on laying and reproductive performance of Pharaoh quail. They were fed ad libitum between 09:00 to 17:00 or full day, daily. Each female-male pair was housed in multiple-bird cages and colony cages. Initial and final body weight, quail-day egg production, feed consumption per egg and mortality were measured to determine laying performance of breeders. A total of 960 eggs were used to determine reproductive performance of quail in each treatment group. Eggs were incubated in a commercial setter and hatcher in standard conditions. Embryonic mortality, apparent fertility, hatchability of total and fertile eggs were calculated to determine the reproductive performance. Results indicated that feeding between 09:00 to 17:00 h reduced final body weight and egg production (p<0.001, p<0.001). Whereas, limited time of feeding improved hatchability of total (p<0.001) and fertile eggs (p<0.001) and reduced embryonic mortality (p<0.001) when compared with the effects of feeding full day. It was found that there were no significant differences for the egg production of quail housed in different cage systems. Quail caged in multiple-bird cages consumed less feed (p<0.01) compared to quail housed in colony cages. There were significant differences for the mortality (p<0.05), hatchability of total (p<0.001) and fertile eggs (p<0.001), and embryonic mortality (p<0.001) during the incubation due to main effect of cage systems. There were significant cage $systems{\times}feeding$ time interactions for hatchability of total and fertile eggs and embryonic mortality (p<0.001). As a conclusion; feeding from 09:00 to 17:00 reduced laying performance of quail and improved the reproductive traits compared to full day feeding of quail breeders. But, further investigations are needed to determine the optimum length of feeding time and egg production of breeders in quail fed limited time must be evaluated in comparison with its beneficial or detrimental effects.

      • KCI등재

        Performance and duration differences between online and paper-pencil tests

        Alper Bayazit,Petek As¸kar 서울대학교 교육연구소 2012 Asia Pacific Education Review Vol.13 No.2

        Digital technologies have been used for measurement purposes and whether the test medium influences the user is an important issue. The aim of this study is to investigate students' performances and duration differences between online and paper-pencil tests. An online testing tool was developed and administered in order to determine the differences between the traditional paper-pencil tests and online tests concerning students' performances and the duration on tests. This tool enables to add questions that utilize an online database and which are in the form of multiple choice (with 5 or 4 options), true-false, matching, filling in the blanks, with multiple answers, with short answers, with long answers, and it also enables to prepare tests and to turn them into paper-pencil test mode. Performance test was applied with both online and paper-pencil modes on junior students at one of the universities in Turkey. Besides, the online testing tool developed within the context of the study was evaluated by instructors with respect to usability, relevance to the purpose and design. Instructor and student questionnaires are developed to determine the opinions on the online testing tool and online tests. Results showed that there was no significant differences between the performances on online and paper-pencil tests. On the other hand, the time they spent on the online test has been longer than the time they spent on paper-pencil test. Students found the online testing tool easy to use and stated that online test medium is more comfortable than paper-pencil tests. However, they complained about external noises, tiredness, and focusing problems regarding the online examination mediums. Generally, instructors have also appreciated the online testing tool's design and they agree on the fact that it serves for its purposes.

      • KCI등재

        Evaluation and follow-up of pain, fatigue, and quality of life in COVID-19 patients

        Sevda Adar,Petek Şarlak Konya,Ali İzzet Akçin,Ümit Dündar,Neşe Demirtürk 질병관리본부 2023 Osong Public Health and Research Persptectives Vol.14 No.1

        Objectives: We evaluated pain, fatigue, anxiety, depression, and quality of life in patients hospitalized for coronavirus disease 2019 (COVID-19) and observed them over a period of 3 months. We also investigated the relationship of these symptoms to age, sex, disease severity, and levels of anxiety and depression. Methods: The study included 100 confirmed COVID-19 patients (i.e., positive on a polymerase chain reaction test) between the ages of 18 and 75 years. Pain (visual analog scale [VAS]), fatigue (fatigue severity scale), anxiety, and depression (hospital anxiety and depression scales) were evaluated on the first day of hospitalization and at 1-month and 3-month follow-ups. The short form-12 questionnaire was used to measure quality of life at the 1-month and 3-month follow-ups. Results: No differences were found in pain, fatigue, anxiety levels, depression levels, and quality of life according to disease severity. High VAS scores at hospital admission were related to continued pain at the 3-month follow-up (odds ratio [OR], 1.067; p<0.001). High VAS (OR, 1.072; p=0.003) and anxiety levels (OR, 1.360; p=0.007) were related to severe fatigue at the 3-month evaluation. Conclusion: Pain, fatigue, anxiety, and depression appear to be long-term sequelae of COVID-19 and can affect quality of life. High VAS and anxiety levels were found to be associated with long-term fatigue.

      • SCOPUSKCI등재

        Potential of fascaplysin and palauolide from Fascaplysinopsis cf reticulata to reduce the risk of bacterial infection in fish farming

        Mai, Tepoerau,Toullec, Jordan,Wynsberge, Simon Van,Besson, Marc,Soulet, Stephanie,Petek, Sylvain,Aliotti, Emmanuelle,Ekins, Merrick,Hall, Kathryn,Erpenbeck, Dirk,Lecchini, David,Beniddir, Mehdi A.,Sau The Korean Society of Fisheries and Aquatic Scienc 2019 Fisheries and Aquatic Sciences Vol.22 No.12

        Marine natural products isolated from the sponge Fascaplysinopsis cf reticulata, in French Polynesia, were investigated as an alternative to antibiotics to control pathogens in aquaculture. The overuse of antibiotics in aquaculture is largely considered to be an environmental pollution, because it supports the transfer of antibiotic resistance genes within the aquatic environment. One environmentally friendly alternative to antibiotics is the use of quorum sensing inhibitors (QSIs). Quorum sensing (QS) is a regulatory mechanism in bacteria which control virulence factors through the secretion of autoinducers (AIs), such as acyl-homoserine lactone (AHL) in gram-negative bacteria. Vibrio harveyi QS is controlled through three parallel pathways: HAI-1, AI-2, and CAI-1. Bioassay-guided purification of F. cf reticulata extract was conducted on two bacterial species, i.e., Tenacibaculum maritimum and V. harveyi for antibiotic and QS inhibition bioactivities. Toxicity bioassay of fractions was also evaluated on the freshwater fish Poecilia reticulata and the marine fish Acanthurus triostegus. Cyclohexanic and dichloromethane fractions of F. cf reticulata exhibited QS inhibition on V. harveyi and antibiotic bioactivities on V. harveyi and T. maritimum, respectively. Palauolide (1) and fascaplysin (2) were purified as major molecules from the cyclohexanic and dichloromethane fractions, respectively. Palauolide inhibited QS of V. harveyi through HAI-1 QS pathway at 50 ㎍ ml<sup>-1</sup> (26 μM), while fascaplysin affected the bacterial growth of V. harveyi (50 ㎍ ml<sup>-1</sup>) and T. maritimum (0.25 ㎍). The toxicity of fascaplysin-enriched fraction (FEF) was evaluated and exhibited a toxic effect against fish at 50 ㎍ ml<sup>-1</sup>. This study demonstrated for the first time the QSI potential of palauolide (1). Future research may assess the toxicity of both the cyclohexanic fraction of the sponge and palauolide (1) on fish, to confirm their potential as alternative to antibiotics in fish farming.

      • KCI등재

        Potential of fascaplysin and palauolide from Fascaplysinopsis cf reticulata to reduce the risk of bacterial infection in fish farming

        Tepoerau Mai,Jordan Toullec,Simon Van Wynsberge,Marc Besson,Stephanie Soulet,Sylvain Petek,Emmanuelle Aliotti,Merrick Ekins,Kathryn Hall,Dirk Erpenbeck,David Lecchini,Mehdi A. Beniddir,Denis Saulnier 한국수산과학회 2019 Fisheries and Aquatic Sciences Vol.22 No.4

        Marine natural products isolated from the sponge Fascaplysinopsis cf reticulata, in French Polynesia, were investigated as an alternative to antibiotics to control pathogens in aquaculture. The overuse of antibiotics in aquaculture is largely considered to be an environmental pollution, because it supports the transfer of antibiotic resistance genes within the aquatic environment. One environmentally friendly alternative to antibiotics is the use of quorum sensing inhibitors (QSIs). Quorum sensing (QS) is a regulatory mechanism in bacteria which control virulence factors through the secretion of autoinducers (AIs), such as acyl-homoserine lactone (AHL) in gramnegative bacteria. Vibrio harveyi QS is controlled through three parallel pathways: HAI-1, AI-2, and CAI-1. Bioassayguided purification of F. cf reticulata extract was conducted on two bacterial species, i.e., Tenacibaculum maritimum and V. harveyi for antibiotic and QS inhibition bioactivities. Toxicity bioassay of fractions was also evaluated on the freshwater fish Poecilia reticulata and the marine fish Acanthurus triostegus. Cyclohexanic and dichloromethane fractions of F. cf reticulata exhibited QS inhibition on V. harveyi and antibiotic bioactivities on V. harveyi and T. maritimum, respectively. Palauolide (1) and fascaplysin (2) were purified as major molecules from the cyclohexanic and dichloromethane fractions, respectively. Palauolide inhibited QS of V. harveyi through HAI-1 QS pathway at 50 μg ml–1 (26 μM), while fascaplysin affected the bacterial growth of V. harveyi (50 μg ml–1) and T. maritimum (0.25 μg). The toxicity of fascaplysin-enriched fraction (FEF) was evaluated and exhibited a toxic effect against fish at 50 μg ml–1. This study demonstrated for the first time the QSI potential of palauolide (1). Future research may assess the toxicity of both the cyclohexanic fraction of the sponge and palauolide (1) on fish, to confirm their potential as alternative to antibiotics in fish farming.

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