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Toxic effect of titanium dioxide nanoparticles on human mesenchymal stem cells
Peralta‑Vega Adriana‑Berenice,Parra‑Barrera Alberto,Ramos‑Godínez María del Pilar,López‑Marure Rebeca,Arellano‑Galindo José,Gisela Gutiérrez‑Iglesias 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.3
Background Titanium dioxide ( TiO2) is employed in the production of cosmetics, sunscreen, food, and drugs; however, TiO2 is toxic at the nanometric scale. Objective To analyze the in vitro toxic effect of TiO2 NPs on mesenchymal stem cells (hMSCs). Methods The hMSCs from Wharton`s jelly were exposed to 4, 62.5 and 500 μg/mL of TiO2 NPs. Viability and cell proliferation tests were carried out at 2, 5 and 7 days of exposure. Additionally, the osteogenic and adipogenic differentiation capacity was evaluated. Results TiO2 NPs had a perinuclear arrangement and internalized in vesicles into cytosol, diminished significantly the viability (40% and 30% and 30%) and the proliferation cellular (35%, 50% and 55%), differentiation to osteoblast (38%) and adipoblasts (20%). Conclusion TiO2 NPs affect viability, proliferation, and differentiation of hMSCs. Our result suggests more regulation of the use of TiO2.
Electrochemical Study of Three Stainless Steel Alloys and Titanium Metal in Cola Soft Drinks
Peralta-Lopez, D.,Sotelo-Mazon, O.,Henao, J.,Porcayo-Calderon, J.,Valdez, S.,Salinas-Solano, G.,Martinez-Gomez, L. The Korean Electrochemical Society 2017 Journal of electrochemical science and technology Vol.8 No.4
Stainless steels and titanium alloys are widely used in the medical industry as replacement materials. These materials may be affected by the conditions and type of environment. In the same manner, soft drinks are widely consumed products. It is of interest for dental industry to know the behavior of medical-grade alloys when these are in contact with soft drinks, since any excessive ion release can suppose a risk for human health. In the present study, the electrochemical behavior of three stainless steel alloys and pure titanium was analyzed using three types of cola soft drinks as electrolyte. The objective of this study was to evaluate the response of these metallic materials in each type of solution (cola standard, light and zero). Different electrochemical techniques were used for the evaluation of the alloys, namely potentiodynamic polarization, linear polarization, and open-circuit potential measurements. The corrosion resistance of the stainless-steel alloys and titanium in the cola soft drinks was provided by the formation of a stable passive film formed by metal oxides. Scanning electron microscopy was used as a complementary technique to reveal corrosion phenomena at the surface of the materials evaluated.
Maria Victoria Peralta 육아정책연구소 2011 International Journal of Child Care and Education Vol.5 No.1
Comparative studies in public policy is, in general, an important area, suitable for deep analysis, since it indicates how the State creates a hierarchy of different development sectors that have an impact nationwide, as well as telling us exactly what the end policy product is. With this in mind, the analysis of these policies in emerging countries becomes a particularly interesting field, since it implies that some prioritizations in economical and social contexts are not relatively complex. In this sense, as part of Latin America, Chile is an interesting case to analyze, since in its earliest years as a republic it was concerned about early childhood education. This means that since the first experiences in the 19th Century, an institutional legal basis has been created in the ECEC field. This has made it possible to establish increasingly challenging public policies as seen in the recently created social protection program, “Chile Crece contigo” (Chile Grows with You). This article aims at providing a historical account of the development of public policies in this field, by analyzing their origins and most particularly, their present status. This current situation allows Chile to assist 50% of the population of those aged 0 to 6 in various institutions and in different ways, mainly with public funding (83%).
Prevalence of Functional Gastrointestinal Disorders in School Children and Adolescents
Juan Javier Peralta-Palmezano,Rafael Guerrero-Lozano 대한소화기학회 2019 대한소화기학회지 Vol.73 No.4
Background/Aims: The epidemiology of functional gastrointestinal disorders (FGIDs) in developed and developing countries involves a high prevalence of constipation and irritable bowel syndrome. This study examined the prevalence of functional gastrointestinal disorders in schoolchildren and adolescents in Colombia using the Rome III criteria. Methods: A cross-sectional study was performed on Colombian children between 8 and 17 years old. The Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version self-report form was answered by students from two schools. The prevalence of FGID was calculated and correlation tests were conducted among the variables analyzed. Results: A total of 864 children with a mean age of 12.5±2.5 years were analyzed; 50.7% were female. Two hundred and fifty-nine children (30%) had at least one FGID, and of these, 163 were female (62.9%). Sixty-nine children had two or more FGIDs (8%). Functional constipation was the most prevalent disorder (13.2%), followed in order by abdominal migraine (8.3%), irritable bowel syndrome (6.9%), and aerophagia (3.1%). A significantly higher prevalence of FGID was observed in females (p=0.000). No significant difference was observed between the age groups or type of school they attended. Conclusions: The overall prevalence of FGID in the sample was 30%, with functional constipation being the most common. These results are similar to those of other prevalence studies reported elsewhere.
Torres-Gómez Mariano,Gómez-Peralta Marlene,Vázquez-Marrufo Gerardo 한국식품연구원 2023 Journal of Ethnic Foods Vol.10 No.4
Among Mesoamerican cultures, P’urhépecha settlers inhabiting Michoacán State in Central Mexico preserve ancestral tradition on mushrooms eating. Most mycological knowledge available for this ethnical group has been addressed in the Pátzcuaro’s Lake zone, whereas P’urhépecha communities in other cultural and ecological relevant geographic areas remain unstudied. Thus, this work describes the ethnomycological knowledge of a scarcely analyzed Arantepacua P’urhépecha community at Michoacán Plateau region. Through structured interviews and field collections, data on the use, knowledge, biomass extraction and nomenclature of wild mushrooms were obtained. A list of P’urhépecha names to design 16 wild mushrooms species and 11 fruitbody components is documented and studied community used Spanish popular names to describe 21 wild mushrooms species and 11 fruitbody structures. Most valuable consumed mushroom species for Arantepacua settlers belong to the Amanita, Boletus, Hypomyces and Ramaria genera. Gender roles on mushrooms collect and cooking, new terms in P’urhépecha dialect to refer the parts of a fruitbody and vegetative mycelium, as well as local recipes and nutritional relevance of the mushroom species consumed by studied community are addressed and discussed. The ethnomycological knowledge documented contributes new terms in P’urhépecha to name the parts of an agarical fruitbody, the mycelium and empirical knowledge about mycorrhizal associations. This was the first P’urhépecha ethnomycological study made outside the Lake Pátzcuaro basin.
Electrochemical oxidation of methyl orange azo dye at pilot flow plant using BDD technology
Cecilia Ramırez,Juan M. Peralta-Hernandez,Adriana Saldana,Berenice Hernandez,Roberto Acero,Ricardo Guerra,Sergi Garcia-Segura,Enric Brillas 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.2
Solutions of methyl orange azo dye were degraded by electrochemical oxidation using a 3 L flow plant with a boron-doped diamond (BDD)/stainless steel cell operating at constant current density, ambient temperature and liquid flow rate of 12 L min-1. A 23 factorial design considering the applied current density, azo dye concentration and electrolysis time as variable independents was used to analyze the process by response surface methodology. LC–MS analysis revealed the formation of seven oxidation products from the cleavage of the –N55N– group of the dye, followed by deamination, formation of a nitro group and/or desulfonation of the resulting aromatics.