Performance Enhancements in LiCl-H2O and LiBr-H2O Absorption Cooling Systems through an Advanced Exergetic Analysis

Parth Mody,Jatin Patel,Nishant Modi,Bhargav Pandya 대한설비공학회 2021 International Journal of Air-Conditioning and Refr Vol.29 No.1

This research study compares the thermodynamic performance of 10 kW lithium chloride–water (LiCl–H2O) and lithium bromide–water (LiBr–H2O) absorption cooling systems through first and second law of thermodynamics. Further, the exergy degradations happening in each component have been split into unavoidable and avoidable exergy degradations as well as endogenous and exogenous exergy degradations through advanced exergy analysis. Pressure–temperature–concentration (P–T –X) diagrams are drafted to clarify the real, ideal, and unavoidable cycles for LiCl–H2O and LiBr–H2O absorption cycles. Moreover, this paper exhibits the sensitivity of various system components towards the generator, condenser, and absorber temperature for both pairs. Energetic observation proves that LiCl–H2O pair is 10% more efficient as compared to LiBr–H2O pair. Exergetically, LiBr–H2O cycle struggles with additional (nearly 13.45%) exergy destruction than LiCl–H2O cycle. The major contribution (around 70% to 80%) of irreversibility comes from the generator and absorber. Comprehensively, the parametric partitions of irreversibility rate in each component provide broad indications to prioritize the system components for enhancements.

Hong Kong`s Interest - Rate Cartel

Parth J . Shah 한양대학교 경제연구소 1997 JOURNAL OF ECONOMIC RESEARCH Vol.2 No.2

Ultrasonic Bone Scalpel versus Conventional Methods for Osteotomy in Posterior Surgery for Cervical Spondylotic Myelopathy: A Review and Meta-Analysis

Bansal Parth,Kumar Vishal,Vatkar Arvind Janardhan,Gaurav Ankit,Dhatt Sarvdeep Singh 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.5

Posterior methods for cervical myelopathy include laminoplasty and laminectomy with/without fusion. A more recent innovation in these treatments is the use of an ultrasonic bone shaver for osteotomy. In this study, we examined the perioperative results after laminectomy/laminoplasty between conventional methods (rongeur/high-speed drill) vs. piezosurgery-based instruments. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed and the search was performed on four databases (PubMed, Scopus, EMBASE, and Google Scholar). Seven comparative studies were chosen after thorough screening by the authors and a meta-analysis was performed between piezosurgery and conventional technique to ascertain intraoperative and postoperative results after laminectomy/laminoplasty. The analysis includes four retrospective cohort studies and three randomized controlled trials published between 2015 and 2022. The mean age ranged from 55.5 to 64.2 years. Blood loss was significantly reduced in the piezosurgery group, other findings were not significant. On subgroup analysis, laminoplasty dramatically reduced blood loss and the rate of iatrogenic dural rips in the piezosurgery group. The use of ultrasonic bone shaver for osteotomy in cervical spondylotic myelopathy is related to significantly decreased blood loss and no significant increase in postoperative drainage, operative time, complication rate, and functional outcomes as compared to traditional techniques. We noticed significantly reduced blood and rate of dural tears in the laminoplasty subgroup with the use of ultrasonic bone shaver, which was not mirrored in the laminectomy subgroup. Careful intraoperative handling of the instrument can help prevent iatrogenic dural tears and nerve damage.

Synthesis and Properties of Novel Biomaterials based on Cyclic Acetal

Sachiko Kaihara,Parth Modi,Kazunobu Toshima,John P. Fisher,Shuichi Matsumura 한국고분자학회 2006 한국고분자학회 학술대회 연구논문 초록집 Vol.2006 No.10

Sandwiched osmotic tablet for controlled release of metoprolol succinate

Aliasgar Kundawala,Parth Sheth,Deepak Maheshwari 한국약제학회 2016 Journal of Pharmaceutical Investigation Vol.46 No.1

In this study novel concept of osmotically controlled drug delivery system in the form of three layered sandwiched tablet (SOT) was introduced. The tablets were prepared and optimized by design of experiment method. Metoprolol succinate, an antihypertensive agent, was selected model drug. Modified Ishikawa diagram was used to understand critical parameters that might affect the final product. Sandwiched osmotic tablets were prepared by direct compression and coated with cellulose acetate film. The process and formulation parameters were initially screened by Plackett–Burman design and later optimized by Box Behnken design. From the tablets we evaluated hardness, friability, weight variation, weight gain, coating uniformity and in vitro drug release as critical quality attributes. The amount of sodium chloride, polyethylene oxide and hydroxypropyl methylcellulose were found to influence the drug release rate from SOT as evident from Plackett–Burman design. Further these factors were optimized to get extended drug release of 80 % or more in 20 h. Optimized formulation batches (BBD8 and BBD5) showed drug release of 79.62 ± 1.19 and 82.46 ± 0.45 % respectively in 20 h with diffusion controlled zero order drug release. The check point batch prepared showed drug release of 80.86 % in 20 h. The prepared osmotically controlled sandwiched tablet showed potential to control the drug release with zero order kinetics.

Polymeric nanoparticles as dual-imaging probes for cancer management

Menon, Jyothi U.,Jadeja, Parth,Tambe, Pranjali,Thakore, Dheeraj,Zhang, Shanrong,Takahashi, Masaya,Xie, Zhiwei,Yang, Jian,Nguyen, Kytai T. Techno-Press 2016 Biomaterials and Biomechanics in Bioengineering Vol.3 No.3

This article reports the development of biodegradable photoluminescent polymer (BPLP)-based nanoparticles (NPs) incorporating either magnetic nanoparticles (BPLP-MNPs) or gadopentate dimeglumine (BPLP-Gd NPs), for cancer diagnosis and treatment. The aim of the study is to compare these nanoparticles in terms of their surface properties, fluorescence intensities, MR imaging capabilities, and in vitro characteristics to choose the most promising dual-imaging nanoprobe. Results indicate that BPLP-MNPs and BPLP-Gd NPs had a size of $195{\pm}43nm$ and $161{\pm}55nm$, respectively and showed good stability in DI water and 10% serum for 5 days. BPLP-Gd NPs showed similar fluorescence as the original BPLP materials under UV light, whereas BPLP-MNPs showed comparatively less fluorescence. VSM and MRI confirmed that the NPs retained their magnetic properties following encapsulation within BPLP. Further, in vitro studies using HPV-7 immortalized prostate epithelial cells and human dermal fibroblasts (HDFs) showed > 70% cell viability up to $100{\mu}g/ml$ NP concentration. Dose-dependent uptake of both types of NPs by PC3 and LNCaP prostate cancer cells was also observed. Thus, our results indicate that BPLP-Gd NPs would be more appropriate for use as a dual-imaging probe as the contrast agent does not mask the fluorescence of the polymer. Future studies would involve in vivo imaging following administration of BPLP-Gd NPs for biomedical applications including cancer detection.

Effect of Drain Duration and Output on Perioperative Outcomes and Readmissions after Lumbar Spine Surgery

Karamian Brian,Kothari Parth,Toci Gregory,Lambrechts Mark James,Canseco Jose,Mao Jennifer,Narayan Raj,Alfonsi Samuel,Sirch Francis,Kheir Nadim,Semenza Nicholas,Woods Barrett,Rihn Jeffrey,Kurd Mark,Rad 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.2

Study Design: Single-center retrospective cohort.Purpose: To compare surgical outcomes of patients based on lumbar drain variables relating to output and duration. Overview of Literature: The use of drains following lumbar spine surgery, specifically with respect to hospital readmission, postoperative hematoma, postoperative anemia, and surgical site infections, has been controversial.Methods: Patients aged ≥18 years who underwent lumbar fusion with a postoperative drain between 2017 and 2020 were included and grouped based on hospital readmission status, last 8-hour drain output (<40 mL cutoff), or drain duration (2 days cutoff). Total output of all drains, total output of the primary drain, drain duration in days, drain output per day, last 8-hour output, penultimate 8-hour output, and last 8-hour delta (last 8-hour output subtracted by penultimate 8-hour output) were collected. Continuous and categorical data were compared between groups. Multivariate logistic regression analysis and receiver operating characteristic (ROC) analysis were performed to determine whether drain variables can predict hospital readmission, postoperative blood transfusions, and postoperative anemia. Alpha was 0.05.Results: Our cohort consisted of 1,166 patients with 111 (9.5%) hospital readmissions. Results of regression analysis did not identify any of the drain variables as independent predictors of hospital readmission, postoperative blood transfusion, or postoperative anemia. ROC analysis demonstrated the drain variables to be poor predictors of hospital readmission, with the highest area under curve of 0.524 (drain duration), corresponding to a sensitivity of 61.3% and specificity of 49.9%.Conclusions: Drain output or duration did not affect readmission rates following lumbar spine surgery.

Analysis and structural design of various turbine blades under variable conditions: A review

Saif, Mohd,Mullick, Parth,Imam, Ashhad Techno-Press 2019 Advances in materials research Vol.8 No.1

This paper presents a review study for energy-efficient gas turbines (GTs) with cycles which contributes significantly towards sustainable usage. Nonetheless, these progressive engines, operative at turbine inlet temperatures as high as $1600^{\circ}C$, require the employment of highly creep resistant materials for use in hotter section components of gas turbines like combustion chamber and blades. However, the gas turbine obtain its driving power by utilizing the energy of treated gases and air which is at piercing temperature and pushing by expanding through the several rings of steady and vibratory blades. Since the turbine blades works at very high temperature and pressure, high stress concentration are observed on the blades. With the increasing demand of service, to provide adequate efficiency and power within the optimized level, turbine blades are to be made of those materials which can withstand high thermal and working load condition for longer cycle time. This paper depicts the recent developments in the field of implementing the best suited materials for the GTs, selection of proper Thermal Barrier Coating (TBC), fracture analysis and experiments on failed or used turbine blades and several other designing and operating factors which are effecting the blade life and efficiency. It is revealed that Nickel based Superalloys were promising, Cast Iron with Zirconium and Pt-Al coatings are used as best TBC material, material defects are the foremost and prominent reason for blade failure.

Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery in Adulthood: Challenges and Outcomes

Jignesh Kothari,Ketav Lakhia,Parth Solanki,Divyakant Parmar,Hiren Boraniya,Sanjay Patel 대한흉부외과학회 2016 Journal of Chest Surgery (J Chest Surg) Vol.49 No.5

Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is an extremely rare, potentially fatal, congenital anomaly with a high mortality rate in the first year of life. It occurs rarely in ad ulthood and may a ppear with m alignant v entricular a rrhythmia or s ud d e n d eath. W e report a c ase of a 49-year-old woman with ALCAPA who presented with dyspnea on exertion. Management was coronary artery bypass grafting to the left anterior descending artery and obtuse marginal arteries, closure of the left main coronary artery ostium, and reestablishment of the dual coronary artery system.

Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis

Kaveri Purandhar,Prasant Kumar Jena,Bhumika Prajapati,Parth Rajput,Sriram Seshadri 대한남성과학회 2014 The World Journal of Men's Health Vol.32 No.3

Heat shock proteins (HSPs) play a role in the homeostasis, apoptosis regulation and the maintenance of the various other physiological processes. Aging is accompanied by a decrease in the resistance to environmental stress, while mitochondria are primary targets in the process of aging, their expression decreasing with age. Mitochondrion also plays a significant role in the process of spermatogenesis. HSPs have been shown to be involved in apoptosis with some of acting as apoptotic inhibitors and are involved in cytoprotection. In this review we discuss the roles of Hsp 27, 60, 70, and 90 in aging and male infertility and have concluded that these particular HSPs can be used as a molecular markers for mitochondrially- mediated apoptosis, aging and male infertility.