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상용차 운전자의 행동특성을 고려한 내장 설계 요구사항 도출
Youngjae Lim,Sungjoon Park,Dohoon Kim,Eui S. Jung,Jaekyu Park,Kwangjin Oh 대한인간공학회 2011 대한인간공학회 학술대회논문집 Vol.2011 No.5
Recently, the cabin of the commercial vehicle can be defined in a variety of ways from a driving space to an essential living area or even mobile office space. Thus, the research scope of commercial vehicle should be expanded to reflect a variety of customer activities and enhance usability in package design. The objective of this paper is to investigate the behavioral characteristics while commercial vehicle driving. The main user activities, a total of 59 relevant to commercial vehicle drivers, are selected and classified into three groups; critical, significant and moderate. The behavioral observation is also conducted to capture the important scene by recording the activities in cabin. By taking advantage of observations, the user requirements needed to improve high are derived. The results show that the driver's waist was bent too much when using the navigation system. In addition, the center-console causes a significant interference for movement between driver seat and rear-bed. The attractive package items and recommendations from the user-centric perspective can be made based on ergonomic evaluation.
( Youngjae Park ),( Jennifer Lee ),( Jung Hee Koh ),( Jung Yoon Choe ),( Yoon-kyoung Sung ),( Shin-seok Lee ),( Ji-min Kim ),( Sung-hwan Park ),( Seung-ki Kwok ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.6
Background/Aims: This study was performed to clarify influences of anticentromere antibody (ACA) on clinical phenotypes of primary Sjögren’s syndrome (pSS) patients in Korea. Methods: We assessed 318 patients who met the 2016 American College of Rheumatology/European League Against Rheumatism classification criteria for pSS. All patients were selected from the Korean Initiative of primary Sjögren’s Syndrome (KISS), a prospective cohort. Among them, 53 patients were positive for ACA, while another 265 patients were not. We compared various clinical data including demographic features, extra-glandular manifestations (EGMs), clinical indices, and laboratory values available from the KISS database between the two groups. Results: Patients in the ACA-positive pSS group were older (p = 0.042), and had higher xerostomia inventory scores (p = 0.040), whereas glandular dysfunction represented with Schirmer I test was more severe in the ACA-negative group. More frequent Raynaud’s phenomenon and liver involvement (both p < 0.001) and less articular involvement (p = 0.037) were observed among the EGMs in the ACA-positive group. Less frequency of leukopenia (p = 0.021), rheumatoid factor (p < 0.001), anti-Ro/SSA antibody positivity (p < 0.001), and hypergammaglobulinemia (p = 0.006), as well as higher positivity rates of anti-nuclear antibody and anti-topoisomerase antibody (p < 0.001 and p = 0.006, respectively) were found in the laboratory data in the ACA-positive pSS group. Conclusions: Considering distinct phenotypes in hematological and serological features and EGMs, we should monitor the occurrence of these clinical features among pSS patients with ACA in caution.
Park Min-Jung,Park Youngjae,Choi Jeong Won,Baek Jin-Ah,Jeong Ha Yeon,Na Hyun Sik,Moon Young-Mee,Cho Mi-La,Park Sung-Hwan 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation, microangiopathy, and progressive fibrosis in the skin and internal organs. To evaluate the pathophysiologic mechanisms and efficacies of potential therapeutics for SSc, a preclinical model recapitulating the disease phenotypes is needed. Here, we introduce a novel animal model for SSc using immunodeficient mice injected with peripheral blood mononuclear cells (PBMCs) from SSc patients. Human PBMCs acquired from SSc patients and healthy controls were transferred into NOD.Cg-PrkdcscidIl2rgtm1Wjl (NSG) mice with concurrent bleomycin injection. Blood, skin, and lung tissues were acquired and analyzed after PBMC engraftment. In addition, we investigated whether the humanized murine model could be used to assess the efficacy of potential therapeutics for SSc. Human PBMCs from SSc patients and healthy controls were engrafted into the blood, skin, and lung tissues of NSG mice. Histological analysis of affected tissues from mice treated with SSc PBMCs (SSc hu-mice) demonstrated substantial inflammation, fibrosis and vasculopathy with human immune cell infiltration and increased expression of IL-17, TGF-β, CCL2, CCL3, and CXCL9. The proportions of circulating and tissue-infiltrating T helper 17 (Th17) cells were elevated in SSc hu-mice. These cells showed increased expression of CXCR3 and phosphorylated STAT3. SSc hu-mice treated with rebamipide and other potential Th17-cell-modulating drugs presented significantly reduced tissue fibrosis. Mice injected with patient-derived PBMCs show promise as an animal model of SSc.
Game theory-based bi-level pricing scheme for smart grid scheduling control algorithm
Park, Youngjae,Kim, Sungwook Editorial Department of Journal of Communications 2016 Journal of communications and networks Vol.18 No.3
<P>Smart grid (SG) technology is now elevating the conventional power grid system to one that functions more cooperatively, responsively, and economically. When applied in an SG the demand side management (DSM) technique can improve its reliability by dynamically changing electricity consumption or rescheduling it. In this paper, we propose a new SG scheduling scheme that uses the DSM technique. To achieve effective SG management, we adopt a mixed pricing strategy based on the Rubinstein-Stahl bargaining game and a repeated game model. The proposed game-based pricing strategy provides energy routing for effective energy sharing and allows consumers to make informed decisions regarding their power consumption. Our approach can encourage consumers to schedule their power consumption profiles independently while minimizing their payment and the peak-to-average ratio (PAR). Through a simulation study, it is demonstrated that the proposed scheme can obtain a better performance than other existing schemes in terms of power consumption, price, average payment, etc.</P>
AVOIDING PERMUTATIONS AND THE NARAYANA NUMBERS
Park, Youngja,Park, Seungkyung Korean Mathematical Society 2013 대한수학회지 Vol.50 No.3
We study 132 avoiding permutations that also avoid $(2r+1)(2r+2){\cdots}12$ but contain $(2r-1)(2r){\cdots}12$ pattern. We find an identity between the number of these permutations and the Narayana number. We also present relations between 132 avoiding permutations and polygon dissections. Finally, a generalization of these permutations is obtained.