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Numerical Analysis of Interfacial Failure Mechanism in Bonded Steel–Concrete Composite Connections
Pankaj Kumar,Arnav Anuj Kasar,Sandeep Chaudhary 한국강구조학회 2023 International Journal of Steel Structures Vol.23 No.5
The formation of steel–concrete composites using individual steel and concrete elements is commonly ensured by two different connection techniques at connected interface level: mechanical connectors and structural adhesives. Among these two connection techniques, the use of structural adhesive for bonding steel and concrete elements is rapidly increasing; primarily owing to uniform transfer of stresses over the entire bonded area. The behaviour of bonded connection with change in adhesive bond layer thickness at the level of composite interface are analysed using finite element analysis under static loading to examine the ultimate strength and shear stresses. The failure governing parameters of bonded connections, such as engendered stresses in terms of von-mises and hydrostatic stresses at bearing ends of the composite interface along with changes in failure patterns (from adhesive to cohesive) are discussed. Also, the maximum engendered stresses along the failure plane for different bond layer thicknesses are examined. In case of one mm bond layer thickness the variation in shear stresses is very high along (39.28 MPa to 23.15 MPa) and perpendicular (34.62 MPa to 16.97 MPa) to the loading direction. While, the specimen with three mm thickness exhibits maximum load bearing capacity, it also has relatively smaller variation in shear stresses along (34.91 MPa to 21.72 MPa) and perpendicular (32.72 MPa to 17.20 MPa), which shows uniformity of stresses with increase in thickness. However, a further increase in the thickness of the bond layer results in reduction in the shear capacity of the specimen.
Lithotomy versus prone position for perianal surgery: a randomized controlled trial
Pankaj Kumar,Tushar S Ghosh,Siddhant Sarthak,Prakash Kumar Sasmal 대한대장항문학회 2022 Annals of Coloproctolgy Vol.38 No.2
Purpose: Studies objectively comparing lithotomy and prone positions regarding surgeon comfort, ergonomics, patient comfort, and position related complications are scarce. Methods: The patients posted for surgery of either fistula in ano, hemorrhoids, or were included in this study. Subjective Mental Effort Questionnaire (SMEQ) and Local Experienced Discomfort (LED) scale were used to score the level of mental and physical stress among the operating surgeon, assistants, and the scrub nurse. Other parameters studied were the exposure of the operative site, patient comfort level, and position-related complications. Results: Thirty patients were operated in each position. Mean±standard deviation of jackknife prone vs. lithotomy surgeon SMEQ score (15.6±10.4 vs. 107.0±11.5, P<0.05) and LED score (1.8±1.5 vs. 6.7±0.5, P<0.05) were found to be statistically significant. Prone vs. lithotomy assistant SMEQ score (29.1±13.1 vs. 100.6±8.7, P<0.05) and LED score (4.6±1.1 vs. 7.4±0.8, P<0.05) were also found to be statistically significant. SMEQ (10.0±0.0 vs. 20.6±2.5, P<0.05) and LED scores (1.1±0.3 vs. 3.3±0.5, P<0.05) of scrub nurses and LED scores (2.5±0.5 vs. 6.3±0.7, P<0.05) of patients were also statistically significant. Exposure of the operative site was significantly better in the prone position (5.0 vs. 2.1, P<0.05). Conclusion: Significantly better SMEQ, LED, and exposure score suggests the superiority of jackknife prone position over the lithotomy in terms of significantly less mental and physical stress to the operating surgeon, assistant, and scrub nurse; better ergonomics, and excellent exposure.
Static and dynamic analysis of cable-suspended concrete beams
Pankaj Kumar,Abhijit Ganguli,Gurmail Benipal 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.64 No.5
A new theory of weightless sagging planer elasto-flexible cables under point loads is developed earlier by the authors and used for predicting the nonlinear dynamic response of cable-suspended linear elastic beams. However, this theory is not valid for nonlinear elastic cracked concrete beams possessing different positive and negative flexural rigidity. In the present paper, the flexural response of simply supported cracked concrete beams suspended from cables by two hangers is presented. Following a procedure established earlier, rate-type constitutive equations and third order nonlinear differential equations of motion for the structures undergoing small elastic displacements are derived. Upon general quasi-static loading, negative nodal forces, moments and support reactions may be introduced in the cable-suspended concrete beams and linear modal frequencies may abruptly change. Subharmonic resonances are predicted under harmonic loading. Uncoupling of the nodal response is proposed as a more general criterion of crossover phenomenon. Significance of the bilinearity ratio of the concrete beam and elasto-configurational displacements of the cable for the structural response is brought out. The relevance of the proposed theory for the analysis and the design of the cable-suspended bridges is critically evaluated.
Morphological and electro-optical responses of dichroic polymer dispersed liquid crystal films
Pankaj Kumar,K.K. Raina 한국물리학회 2007 Current Applied Physics Vol.7 No.6
polymerization induced phase separation technique using nematic liquid crystal material in UV curable polymer NOA 65 and anthra-quinone dichroic dye. The eects of applied voltage and temperature on the LC droplet morphology and its optical characteristics werestudied in detail. Liquid crystal droplets containing low concentration of dye (6 0.25%) in polymer matrix exhibit bipolar conguration atlower applied voltage (6 10 V) whereas at relatively higher voltage (Plow concentration DPDLC lm shows better optical transmission and higher contrast ratio.
( Pankajkumar Ramdas Waghmare ),( Pratima Pankajkumar Waghmare ),( Liwei Gao ),( Wan Sun ),( Yuqi Qin ),( Guodong Liu ),( Yinbo Qu ) 한국미생물생명공학회(구 한국산업미생물학회) 2021 Journal of microbiology and biotechnology Vol.31 No.5
Efficient cellulolytic enzyme production is important for the development of lignocellulose-degrading enzyme mixtures. However, purification of cellulases from their native hosts is time- and labor-consuming. In this study, a constitutive expression system was developed in Penicillium oxalicum for the secreted production of proteins. Using a constitutive polyubiquitin gene promoter and cultivating with glucose as the sole carbon source, nine cellulolytic enzymes of different origins with relatively high purity were produced within 48 h. When supplemented to a commercial cellulase preparation, cellobiohydrolase I from P. funiculosum and cellobiohydrolase II from Talaromyces verruculosus showed remarkable enhancing effects on the hydrolysis of steam-exploded corn stover. Additionally, a synergistic effect was observed for these two cellobiohydrolases during the hydrolysis. Taken together, the constitutive expression system provides a convenient tool for the production of cellulolytic enzymes, which is expected to be useful in the development of highly efficient lignocellulose-degrading enzyme mixtures.
Pankajkumar Yadav,Ekta Yadav,Amita Verma,Saima Amin 한국약제학회 2014 Journal of Pharmaceutical Investigation Vol.44 No.6
Poor water solubility is one of the reasons forerratic absorption after oral administration of furosemide(FSM), an antihypertensive loop diuretic. Self nano emulsifyingdrug delivery system (SNEDDS) is a novel drugdelivery system utilized to improve the water solubility,permeability and ultimately bioavailability. FSM solubilitywas determined in various vehicles oils, surfactants and cosurfactants. Self emulsification region for the rationaldesign of SNEDDS formulations were identified bypseudoternary diagrams. Developed formulations werecharacterized by zeta potential determination, droplet sizeanalysis, dilution test, viscosity determination, in vitrodissolution studies and in vivo pharmacodynamic evaluation. A remarkable increase in dissolution was observed forthe optimized SNEDDS when compared with the plainFSM and marketed formulation by in vitro dissolutionstudies. The pharmacological effect of FSM was improvedby SNEDDS formulation as compared to plain FSM. Thestudy confirmed that the SNEDDS formulation can be usedas a possible alternative to traditional oral formulations ofFSM to improve its bioavailability.
Novel self nano emulsifying formulation of furosemide: a drug used in pulmonary edema
( Pankajkumar Yadav ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Purpose: Poor water solubility is one of the reasons for erratic absorption after oral administration of furosemide (FSM), an antihypertensive loop diuretic indicated for pulmonary edema. Aim of this study was to utilize Self nano emulsifying drug delivery system (SNEDDS), a novel drug delivery system, for improvement of water solubility, permeability and ultimately bioavailability of FSM. Methods: FSM solubility was determined in various vehicles oils, surfactants and co surfactants. Self emulsification region for the rational design of SNEDDS formulations was identified by pseudoternary diagrams. Developed formulations were characterized by zeta potential determination, droplet size analysis, dilution test, viscosity determination, in vitro dissolution studies and in vivo pharmacodynamic evaluation. Results:A remarkable increase in dissolution was observed for the optimized SNEDDS when compared with the plain FSM and marketed formulation by in vitro dissolution studies. The pharmacological effect of FSM was improved by SNEDDS formulation as compared to plain FSM. Conclusion: The study confirmed that SNEDDS formulation can be used as a possible alternative to traditional oral formulations of FSM to improve its bioavailability.