위에 생긴 이소성 췌장의 진단에 있어 경구 조영제로 물을 사용한 후 조영증강 역동적 CT의 가치

조준식,신경숙 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

To describe the usual and unusual CT findings of heterotopic pancreatic of the stomach and to evaluate the usefulness of dynamic contrast-enhanced CT with water as an oral contrast agent in diagnosing heterotopic pancreas We retrospectively reviewed CT findings in 10 patients with pathologically proved gastric heterotopic pancreas by operation (n=9) or endoscopic resection (n=1). In three patients, conventional CT with diluted Gastrografin solution as an oral contrast agent was performed. In seven patients, two-phase dynamic CT scans after ingestion of 600-800 ml of water were obtained in the early phase and equilibrium phase. Dynamic CT findings of heterotopic pancreas were correlated with histopathologic findings. All 10 heterotopic pancreatic rests were detected with conventional CT or dynamic CT. In seven cases who underwent dynamic CT after ingestion of water, highly enhanced mucosal layers overlying the lesions were identified and all lesions were well delineated in the submucosal layer In four of these seven cases, heterotopic pancreas showed high enhancement similar to that of adjacent normal pancreatic enhancement in the early phase of dynamic CT. The usual CT findings of gastric heterotopic pancreas were oval-shaped submucosal masses (<3cm) in the gastric antrum. The unusual CT findings were infiltrating heterotopic pancreas into the muscle layer in one, cystic dilatation of heterotopic pancreatic ducts in two, and malignant change with mucin secreting cystadencoarcinoma in one. Gastric heterotopic pancreas usually showed oval-shaped submucosal masses (<3cm) in the gastric antrum with high enhancement similar the that of pancreatic enhancment in the early phase of dynamic CT. Our results suggest that contrast-enhanced dynamic CT after ingestion of water may be helpful in diagnosing gastric heterotopic pancreas.

종합병원 입원환자의 알코올중독 유병율과 주치의의 인지도 조사

조석군,김경빈,장환일 大韓神經精神醫學會 1993 신경정신의학 Vol.32 No.6

The authors studied prevalence and physician's detection rate of alcoholism in 478 adult patients admitted at Kyung-Hee Medical Center from June to July in 1992. In this study, the authors used self-report questionnaire consisting of Korean version of DSM-Ⅲ-R, MAST, NAST(I)(Alcoholism Screening Test of Seoul National Mental Hospital(I)), and additional demographic questions. The results were as following : 1) Among 478 patients, prevalence of alcoholism was 26.8%(76 patients) in male and 1.6%(e patients) in female. 2) Among the patients who are identified as alcoholism by the authors, detection rates of alcoholism by the charge physicians were 24.2% in internal medicine and none in other departments. 3) Compared to the alcoholic patients who are not detected by the charge physicians, the alcoholic patients who are detected are more aged patients showing high scored MAST significantly and having liver diseases.

청가시덩굴(Smilax sieboldii Miq.)의 잎 및 지하부의 성분과 항고지혈작용에 관한 연구

조경열,우미희,오인숙 대구효성가톨릭대학교 응용과학연구소 1991 응용과학연구논문집 Vol.1 No.-

Nutritional value of the leaf and antihyperlipidemic effect of the subterranean part of Smilax siebolidd Miq.(Liliaceae) were investigated in this experiment. 8 minerals, 17 amino acids and 5 fatty acids were quantitatively analyzed in the leaf. In comparison with other vegetables, the content of amino acids was about twice as much as those and a lot of essential amino acids were found. The content of fatty acids was similar with that of other vegetables. In addition, various trace elements such as Mg, Zn and Mn were contained. The chloroform extract of the subterranean part of this plant was effective to decrease total cholesterol and triglyceride level and decrease HDL-cholesterol level in plasma of mouse.

뿜칠시공에 의한 단면복구재의 시공성 및 공학적 특성에 관한 실험적 연구

조봉석,김영선,장재봉,김용로,김경덕,김무한 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

These days, serious concerns of reinforced concrete have been raised recently over steel-bar corrosion, cracking, the deterioration of durability and structural stress resistance and so on, all due to the effects of exterior factors. Such being the case, in domestic, various repair materials and method systems to keep up with these reinforced concrete deteriorated due to salt damage, carbonation, chemical decay et. developed and applied. However, on-site quality control of various repair materials and method systems isn't achieved desirably because it is depend completely on a men of experience' opinions above all else regardless of various on - site environments. In this background, mock up test with due regard to real on-site environments was performed to secure fundamental data for establishment of desirable on-site quality control. Mock up test using repair mortar analyzed from angles of construction methods, mechanical spraying pressures, W 1M. Construction methods were designed manpower method and spraying method, spraying pressures were designed 32, 42, 52 psi, W/M were designed 14.4, 15.4, 16.4 %. And compressive strength, Chloride ion diffusion coefficient, bond strength, SEM of mock up test specimens were evaluated. In conclusion, we confirmed excellency of mechanical spraying pressures, fined extremely excellency of condition of spraying pressure 42 ps, W/M 14.4% within this study. therefore the results of this study will be useful to provide fundamental data for establishment of desirable on-site quality control.

돈사폐수를 이용한 Polyhydroxyalkanoates의 생산

조경숙,박창호,류희욱 이화여자대학교 환경문제연구소 1997 이화환경연구 Vol.1 No.-

돈사폐수를 발효기질로 이용한 생분해성 고분자, polyhydroxyalkanoates(PHA) 의 생산이 가능하였다. 균주로는 질소 혹은 인 등의 비탄소 영양원의 제한 없이도 PHA 의 생산이 가능한 Azotobacter vinelandii UWD 를 이용하였고 돈사폐수배지에서의 PHA 생산특성을 glucose 합성배지에서의 특성과 비교하였다. A. vinelandii UWD 균주는 탄소원으로 glucose와 alkanoates 가 함유된 배지에서 alkanoates를 우선적으로 소비하여 주로 생장을 하고, glucose소비단계에서는 생장보다는 PHA를 생산하는 diauxic growth 를 하였다. 돈사폐수 원액을 배지로 사용할 경우 UWD 균주의 건조균체량과 PHA 함량이 낮았는데(0.91g/L, 37wt%), 이는 돈사폐수 중에 함유되어 있는 acetate, propionate, butyrate 및 valerate등과 같은 높은 농도의 alkanoates가 세포생장을 저해하기 때문이었다. 증류수로 50% 희석한 배지(총 생산 균체 건중량 2.02g/L)를 사용하는 것이 바람직한 것으로 밝혀졌다. 50% 희석돈사폐수 배지에 glucose를 3% 첨가하면 건조균체량은 9.40g/L로 현저하게 증가하였으며, 균체내 PHA 함량은 58.3%, PHA 생산속도는 0.11g/(L·h)이었다. Glucose 합성배지에서 합성된 PHA는 poly-β-hydroxybutyrate(PHB)의 형태이었고, 돈사폐수 배지로부터는 copolymer인 poly-β-hydroxybutyrate-co-β-hydroxyvalerate, P(HB-co-HV)를 2-8mol%합성할 수 있었다. 돈사폐수배지를 이용하여 PHA를 생산하는 동안 배지의 염도를 대략 50% 정도 제거가 가능하였다. Biodegradable polymer, polyhydroxyalkanoates(PHA), could be produced using swine wastewater (SW) as a fermentation substance. Azotobacter vinelandii UWD was able to produce PHA without limiting non-carbon nutrients such as nitrogen and phosphorous. Production characteristics of strain UWD in SW medium were compared with those in glucose synthetic medium. In the synthetic medium containing glucose and alkanoates as carbon sources. A. vinelandii UWD grew diauxically, first by using alkanoates and then by using glucose to produce biomass PHA. Using raw SW medium, cell mass production was small (0.91g/ L) and PHA content was 37wt% because cell growth was inhibited by alkanoates such as acetate, propionate, butyrate, and valerate contained in SW. Use of two-fold diluted SW as fermentation medium was desirable for PHA production. When 3% of glucose was added to the two-fold diluted SW, dry cell mass increased to 9.40g/L, and the PHA content and PHA production rate were 58.3wt% and 0.11g(L·h), respectively, When grown in SW media A. vinelandii UWD formed PHA copolymers containing β-hydroxybutyrate and β-hydroxyvalerate (HV), and HV content in the copolymer was 2-8mol% whereas homopolymer of poly-β-hydroxybutyrate was produced in the glucose synthetic medium. Approximately, 50% of salinity in the medium was reduced after PHA production using SW medium.

黃菊과 黑薔薇를 이용한 기능성 花茶 개발 Ⅱ.花茶의 품질특성

조경숙,서정근,정형석 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.2

본 연구는 화차의 비율별 제조공정에 따른 화차의 관능적 품질을 평가하기 위해서 수행되었다. 녹차와 꽃의 시료에 대한 색도중 L, a, b값은 녹차가 29.93, -8.24, 9.27로 녹색을, 황국은 47.20, -1.69, 29.12로 밝은 황색을, 흑장미는 37.18, 4.47, 4.12로 흑적색을 띠웠다. 색상과 채도는 황국이 -17.23과 29.17로 가장 높아 색상이 가장 밝고 선명하였으며, 흑장미는 0.92와 6.08로 색상이 어둡고 둔탁한 적색을 띠워 녹차에 꽃을 혼합할 경우 시각적으로 황국은 쉽게 구별이 되었으며 흑장미는 쉽게 구별되지 않았다. 황국 화차는 꽃의 비율이 증가할수록 국화향, 상쾌하고 개운한 단맛의 증가와 더불어 떫은 맛이 감소하였으나, 혼합비율이 9:2 이상일 경우에는 쑥냄새와 같은 강한 국화향이 증가하여 녹차 고유의 향은 거의 상쇄되는 경향이었다. 장미 화차는 장미꽃이 증가할수록 시큼한 장미향이 강하게 증가하였고, 탄닌성분이 많아 떫고 텁텁한 맛과 시큼한 맛이 강한 것으로 평가되었다. 녹차에 알맞은 꽃의 혼합율은 9:1이하의 비율로 혼합했을 때 황국과 흑장미의 꽃잎색이 녹차와 어울려 전체적인 조화성과 풍미, 시각적 아름다움을 증가시켰다. 녹차에 꽃을 혼합한 화차는 녹차 단일의 차보다는 시각적 즐거움과 독특한 방향성이 부가되어 맛과 향이 풍부한 기능성 꽃차 개발에 좋은 재료로 평가되었다. This experiment was carried out to investigate the effect of mixed ratio on the sensory evaluation in manufacture of functional flower tea. Among the chromaticity about green-tea and material flower, the amount of L, a, b of green tea was 29.93, -8.24, 9.27 with green, the amount of a yellow chrysanthemum(C.indicum) was 47.20, -1.69, 29.12 with bright yellow, the amount of a black rose(Rosa hybrida)is 37.18, 4.47, 4.12 with dark red. The yellow chrysanthemum has brightest and most distinct color with -17.23 hue and 29.17 chrome value, but the black rose has dark dead red color with 0.29 hue 6.08 chrome value. When the yellow chrysanthemum mixed with green tea, it was easily distinguished with naked eye. But the black rose was not distinguishable easily. As the retio increase, the yellow chrysanthemum tea has more chrysanthemum scent, increase of refreshing and relieved sweetness, and less astringent taste. If the mixed rate was over 9:2, original scent of green tea was almost offset with strong chrysanthemum scent like mugwort's. As the ratio increase, the rose tea has strongly increased sourish, and because of the tannin it was appraised strong astringent, unpleasant, sourish taste. The best-mixed ratio of green tea and flower is 9:1. When it mixed at this ratio, the yellow chrysanthemum and petal color of black rose was well matched with green tea, and the tea has general harmony and flavor and it is visually beautiful. Flower tea, green tea from flower, has added visually joy and unique fragrance, it was valued as fine material for rich taste and scent technical tea development.

齒周靭帶細胞의 生化學的 特異性에 對한 硏究

趙誠旭,車敬石 대한치과교정학회 1992 대한치과교정학회지 Vol.22 No.1

To find out the differences between periodontal ligament cells (PDL cells) and gingival fibroblast cells (GFB cells), alkaline phosphatase, a marker enzyme for osteoblast, was used to measure the activities and 45CaCl₂isotope was used to find out cellular and release of 45Ca, a requisite for bone formation, PDL cells and GFB cells from 1 to 5 passages were also measured in alkaline phosphatase activity assay. By the use of above methods, followings were concluded that the PDL cells and the GFB cells have characteristics that are different from each other. In that PDL cells showed large amount of calcium uptake ad large amount of calcium release in initial stage, they seem to possess characteristics which are similar to osteoblast-like cells. 1. The PDL cells, in contrast to the gingival fibroblast, showed exceedingly high alkaline phosphatase activity which was highest at the second passage, decreasing thereon. But gingival fibroblasts cells showed no distinct differences in alkaline phosphatase activity as the passage were elapsed. 2. For both PDL cells and GF cells, the 45Ca uptake was greatest at 2 hours period. The PDL cells showed higher measuring than GFB cells through out the whole time period. 3. Whereas the GFB cells showed slow increase of 45Ca release as time relapsed, the PDL cells showed rapid increase of 45Ca release.

식이 조건에 따른 햄스터의 생장과 조직의 비교

조규태,서동석,안경준 西原大學校 基礎科學硏究所 1999 基礎科學硏究論叢 Vol.13 No.-

식이 조건(pellet, mixed pellet, egg yolk)을 달리하였을 때, 햄스터의 체중 증가량, 먹이 소비량 및 식이 효율 그리고 각 장기의 차이점을 비교하였다. 햄스터의 체중 증가량과 먹이 소비량의 비교는 ANOVA 검정과 Duncan이 다중비교검정에 기초를 두었고 식이 효율은 상관관계를 통하여 알아보았다. 혼합된 사료를 먹었을 때가 가장 많은 체중 증가량을 보였고 다음은 사료, 난황 순서로 증가하였다. 그리고 햄스터는 난황보다는 사료와 혼합 사료를 더 좋아하였으며, 난황만 먹인 경우 간조직에서 병적인 변화를 볼 수 있었다. The increase of weight, consumption rate of food, and histological structure of golden hamster were compared under different condition of feed(pellet, mixed pellet, and egg yolk). The comparison of increasing rate of weight and consumption rate of food was based on ANOVA test and Duncan's multiple range test. The golden hamsters fed on mixed pellet showed prominent growth but in the case of egg yolk showed poor growth. The golden hamsters preferred mixed pellet and pellet to egg yolk, and showed abnormal histological change on the liver and kidney tissue when only the egg yolk was fed.

돈사폐수를 이용한 Polyhydroxyalkanoates의 생산

조경숙,류희욱,박창호 이화여자대학교 생명과학연구소 1996 생명과학연구논문집 Vol.7 No.-

돈사페수를 발효기질로 이용한 생분해성 고분자, polyhydroxyalkanoates(PHA)의 생산이 가능하였다. 균주로는 질소 혹은 인 등의 비탄소 영양원의 제한 없이도 PHA의 생산이 가능한 Azotobacter vinelandii UWD를 이용하였고 돈사폐수배지에서의 PHA 생산특성을 glucose 합성배지에서의 특성과 비교하였다. A. vinelandii uwd균주는 탄소원으로 glucose와 alkanoates가 함유된 배지에서 alkanoates를 우선적으로 소비하여 주로 생장을 하고, glucose 소비단계에서는 생장보다는 PHA를 생산하는 diauxic growth를 하였다. 돈사폐수 원액을 배지로 사용할 경우 UWD 균주의 건조균체량과 PHA함량이 낮았는데(0.91 g/L,37 wt%). 이는 돈사폐수 중에 함유되어 있는 acetate, propionate, butyrate 및 valerate 등과 같은 높은 농도의 alkanoates가 세포생장을 저해하기 때문이었다. 증류수로 50% 희석한 배지(총 생산 균체 건중량 2.02g/L)를 사용하는 것이 바람직한 것으로 밝혀졌다. 50% 희석 돈사폐수 배지에 glucose를 3% 첨가하면 건조균체량은 9.40g/L로 현저하게 증가하였으며, 균체내 PHA 함량은 58.3%, PHA 생산속도는 0.11g/(L·h)이었다. Glucose 합성배지에서 합성된 PHA는 poly-β-hydroxybutyrate(PHB)의 형태이었고, 돈사폐수 배지로부터는 copolymer인 poly-β-hydroxybutyrate-co-β-hydroxyvalerate, P(HB-co-HV)를 2-8mol% 합성할 수 있었다. 돈사폐수배지를 이용하여 PHA를 생산하는 동안 배지의 염도를 대략 50% 정도 제거가 가능하였다. Biodegradable polymer, polyhydroxyalkanoates(PHA), could be produced using swine wastewater (SW)as a fermentation substance. Azotobacter vinelandii UWD was able to produce PHA without limiting non-carbon nutrients such as nitrogen and phosphorous. Production characteristics of strain UWD in SW medium were compared with those in glucose sythetic medium In the synthetic medium containing glucose and alkanoates as carbon sources. A vinelandii UWD grew diauxically, first by using alkanoates and then by using glucose to produce biomass and PHA. Using raw SW medium, cell mass production was small(0.91 g/L)and PHA content was 37 wt% because cell growth was inhibited by alkanoates such as acetate, propionate, butyrate, and valerate contained in SW. Use of two-fold diluted SW as fermentation medium was desirable for PHA production. When 3% of glucose was added to the two-fold diluted SW, dry cell mass increased to 9.40 g/L, and the PHA content and PHA production rate were 58.3 wt% and 0.11g/(L·h), respectively. When grown in SW media A. vinelandii UWD formed PHA copolymers containing β-hydroxybutyrate and β-hydroxyvalerate(HV), and HV content in the copolymer was 2-8mol% whereas homopolymer of poly-β-hydroxybutyrate was produced in the glucose synthetic medium. Approximately 50% of salinity in the medium was reduced after PHA production using SW medium.

진행위암의 수술전 병기결정에서 문맥기 나선식 CT의 유용성 : Usefulness of Helical CT during the Portal Venous Phase

조준식,신경숙 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

The purpose of this study was to evaluate the effect of helical CT during the portal venous phase after oral ingestion of water in the preoperative staging of advanced gastric carcinomas. Of the patients underwent helical CT scanning for preoperative staging of gastric carcinoma, 70 patients with pathologically proved advanced gastric carcinomas were selected in this study. The patients ingested 600-800m1 of water as a oral contrast agent before CT scanning. A total 130150ml of nonionic contrast material was administered at the rate of 4ml/s. We obtained portal venous phase images at 60 s and equilibrium phase images at 3 min after the start of bolus administration of intravenous contrast material. Two-phase CT findings were prospectively evaluated and correlated with histopathologic findings according to TNM classification. The primary tumors were detected on CT scans in 69 (98.5%) of 70 cases. The accuracy of CT for T staging was 74.3% (52 of 70 cases). T staging was understaged in 13 cases (18.6%) and overstaged in five (7.1%). The accuracy for N staging was 67.1% (47 of 70 cases). N staging was understaged in 16 cases (22.9%) and overstaged in seven (10%). Our results suggest that helical CT during the portal venous phase can improve the accuracy of CT in the preoperative staging of advanced gastric carcinomas.