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      • Symmetric supercapacitor: Sulphurized graphene and ionic liquid

        Shaikh, Jasmin S.,Shaikh, Navajsharif S.,Kharade, Rohini,Beknalkar, Sonali A.,Patil, Jyoti V.,Suryawanshi, Mahesh P.,Kanjanaboos, Pongsakorn,Hong, Chang Kook,Kim, Jin Hyeok,Patil, Pramod S. Elsevier 2018 JOURNAL OF COLLOID AND INTERFACE SCIENCE - Vol.527 No.-

        <P><B>Abstract</B></P> <P>Symmetric supercapacitor is advanced over simple supercapacitor device due to their stability over a large potential window and high energy density. Graphene is a desired candidate for supercapacitor application since it has a high surface area, good electronic conductivity and high electro chemical stability. There is a pragmatic use of ionic liquid electrolyte for supercapacitor due to its stability over a large potential window, good ionic conductivity and eco-friendly nature. For high performance supercapacitor, the interaction between ionic liquid electrolyte and graphene are crucial for better charge transportation. In respect of this, a three-dimensional (3D) nanoporous honeycomb shaped sulfur embedded graphene (S-graphene) has been synthesized by simple chemical method. Here, the fabrication of high performance symmetric supercapacitor is done by using S-graphene as an electrode and [BMIM-PF<SUB>6</SUB>] as an electrolyte. The particular architecture of S-graphene benefited to reduce the ion diffusion resistance, providing the large surface area for charge transportation and efficient charge storage. The S-graphene and ionic liquid-based symmetric supercapacitor device showed the large potential window of 3.2 V with high energy density 124 Wh kg<SUP>−1</SUP> at 0.2 A g<SUP>−1</SUP> constant applied current density. Furthermore, this device shows good cycling performance (stability) with a capacitive retention of 95% over 20,000 cycles at a higher current density of 2 A g<SUP>−1</SUP>.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • SCISCIESCOPUS

        Non-vacuum mechanochemical route to the synthesis of Cu<sub>2</sub>SnS<sub>3</sub> nano-ink for solar cell applications

        Vanalakar, S.A.,Agawane, G.L.,Shin, S.W.,Yang, H.S.,Patil, P.S.,Kim, J.Y.,Kim, J.H. Elsevier 2015 Acta materialia Vol.85 No.-

        <P><B>Abstract</B></P> <P>Cu-based ternary chalcogenides such as Cu<SUB>2</SUB>SnS<SUB>3</SUB> (CTS) are attracting increasing interest due to their outstanding opto-electronic properties. Herein, a simple, cost-effective non-vacuum mechanochemical synthetic route for preparing CTS nanocrystals with controlled size and composition is presented. CTS nanocrystalline powders were synthesized by ball milling and subsequent annealing in an H<SUB>2</SUB>S atmosphere. These nanocrystal samples were characterized using powder X-ray diffraction (P-XRD), Raman spectroscopy, ultraviolet–visible optical spectroscopy, energy-dispersive X-ray spectroscopy (EDS), field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) techniques. Texture structures with cubic crystallinity were observed from the P-XRD of (112), (200) planes of CTS nanopowders. The EDS results confirmed that the synthesized powders had an appropriate chemical purity. According to TEM/FE-SEM observations, a nanostructure CTS was obtained after 36h of mechanochemical processing followed by annealing. The average particle size of single phase CTS after 48h of milling was ∼45nm. Based on obtained data using characterization methods, reaction mechanism steps were proposed to clarify the reactions that occurred during the mechanochemical process. In order to prepare nanocrystal ink, ethanol was used as a solvent, and polyvinylpyrrolidone, which acts as an organic stabilizing agent, was added to the CTS powder to prepare a printable paste.</P>

      • KCI등재

        Formulation and comparative pharmacokinetic evaluation of orodispersible tablets and films of nebivolol hydrochloride

        P. Vijayanand,J. S. Patil,M. Venkata Reddy 한국약제학회 2015 Journal of Pharmaceutical Investigation Vol.45 No.2

        Objective of the present research work was toprepare orodispersible tablets and orodispersible films ofnebivolol hydrochloride for dysphagic patients. Nebivololhydrochloride, an anti-hypertensive agent, was chosen as amodel drug in this study. Oral bioavailability of Nebivololhydrochloride is only 12 % in humans due to extensive firstpass hepatic metabolism by Cytochrome P450 2D6enzyme. Orodispersible tablets of Nebivolol hydrochloridewere prepared using different sublimating agents likecamphor, menthol and thymol. The orodispersible tabletformulation containing 10 % w/w of menthol showed adisintegration time of 11 s with more than 98 % drugrelease within 14 min. The orodispersible films of Nebivololhydrochloride were prepared using xanthan gum, guargum and sodium alginate as polymers by solvent castingmethod. Formulation containing 1.5 % w/v of sodiumalginate had disintegration time of 14 s with 99 % drugrelease within 10 min. In-vivo studies of both orodispersibletablets and orodispersible films in rabbits showedsignificantly better pharmacokinetic profile (AUC, Tmax,Cmax) compared to marketed conventional tablets of Nebivololhydrochloride. From this study, it was concludedthat both orodispersible tablets and films of Nebivololhydrochloride may prove to be more efficacious in thetreatment of hypertension in dysphagic patients.

      • KCI등재

        Hepatoprotective and antioxidant activities of crude fractions of endophytic fungi of Ocimum sanctum Linn. in rats

        Shukla, S.T.,Kulkarni, V.H.,Habbu, P.V.,Jagadeesh, K.S.,Patil, B.S.,Smita, D.M. 경희한의학연구센터 2012 Oriental Pharmacy and Experimental Medicine Vol.12 No.2

        Endophytic fungi are a rich source of novel organic compounds with interesting biological activities and a high level of biodiversity. In the present investigation, an attempt has been made to isolate, characterize and screen the Tulsi (Ocimum sanctum Linn.) root fungal endophytic fractions (TRF) for hepatoprotective and antioxidant activities. Endophytic fungi from Ocimum sanctum Linn. roots were isolated and cultured aseptically in PDA media. The full fledged grown fungus cultures were fermented in potato dextrose broth and fractionated using ethyl acetate. TRF-1 and TRF-2 were subjected free radical scavenging activities against 2,2-diphenyl-1-picrylhydrazyl, hydroxyl free radicals and reducing power assay. TRF-1 was found to be potential free radical scavenger with $IC_{50}$ values of $71.83{\mu}g/ml$ for DPPH and $110.85{\mu}g/ml$ for hydroxyl radical respectively. TRF-1 and TRF-2 were further assessed for hepatoprotective activity in $CCl_4$ induced hepatotoxicity in-vivo. Results showed that TRF-1 (200 mg/kg p.o.) and TRF-2 (200 mg/kg p.o.) significantly reversed the actions of carbon tetrachloride induced hepatotoxicity, as evident by restoration of serum AST, ALT, ALP, bilirubin, triglycerides and protein level to normal values as compared to $CCl_4$ treated group. Restoration of altered LPO (p<0.001), GSH (p<0.01) and catalase (p<0.01) by TRF-1 suggests that the hepatoprotective activity may be attributed to its antioxidant action. This was further supported by histopathological studies. TRF-1 was subjected to rDNA sequencing studies by PCR technique. Based on the morphological and molecular characterization, the fungus was identified as Paecilomyces variotti Bain. Therefore, endophytes from medicinal plants represent great potential for the discovery of new pharmacologically active metabolites.

      • KCI등재

        Band gap tunable and improved microstructure characteristics of Cu2ZnSn(S1-x,Sex)4 thin films by annealing under atmosphere containing S and Se

        신승욱,In-YoungKim,GURAV KISHOR VISHWANATH,Chae Hwan Jeong,Jae Ho Yun,P.S. Patil,이정용,Jin Hyeok Kim 한국물리학회 2013 Current Applied Physics Vol.13 No.8

        Cu2ZnSn(SxS1-x)4 (CZTSSe) thin films were prepared by annealing a stacked precursor prepared on Mo coated glass substrates by the sputtering technique. The stacked precursor thin films were prepared from Cu, SnS2, and ZnS targets at room temperature with stacking orders of Cu/SnS2/ZnS. The stacked precursor thin films were annealed using a tubular two zone furnace system under a mixed N2 (95%) þ H2S (5%) þ Se vaporization atmosphere at 580 ℃ for 2 h. The effects of different Se vaporization temperature from 250 C to 500 ℃ on the structural, morphological, chemical, and optical properties of the CZTSSe thin films were investigated. X-ray diffraction patterns, Raman spectroscopy, and X-ray photoelectron spectroscopy results showed that the annealed thin films had a single kesterite crystal structure without a secondary phase. The 2q angle position for the peaks from the (112) plane in the annealed thin films decreased with increasing Se vaporization temperature. Energy dispersive X-ray results showed that the presence of Se in annealed thin films increased from 0 at% to 42.7 at% with increasing Se vaporization temperatures. UVeVIS spectroscopy results showed that the absorption coefficient of all the annealed thin films was over 104 cm-1 and that the optical band gap energy decreased from 1.5 eV to 1.05 eV with increasing Se vaporization temperature.

      • KCI등재

        Herbal anti-inflammatory immunomodulators as host modulators in chronic periodontitis patients: a randomised, double-blind, placebo-controlled, clinical trial

        Girish D. Deore,Abhijit N. Gurav,Rahul Patil,Abhijeet R. Shete,Ritam S. Naiktari,Saurabh P. Inamdar 대한치주과학회 2014 Journal of Periodontal & Implant Science Vol.44 No.2

        Purpose: Host modulatory therapy has been proposed as a treatment for periodontal diseases. A class of herbal medicines, known to be immunomodulators, alters the activity ofimmune function through the regulation of informational molecules such as cytokines. Inthe current study, we tested the hypothesis that herbal immunomodulator drugs act as anadjuvant to scaling and root planing (SRP) in alleviating periodontal inflammation by improvingclinical and biochemical parameters. Methods: Sixty healthy subjects (30 in each group) with moderate and severe chronic periodontitiswere enrolled in a double-blind, placebo-controlled, double-masked randomisedcontrolled trial. The control group was treated with SRP and a placebo, whereas the testgroup was treated with SRP followed by dietary supplementation of Septilin for 3 weeks. Periodontal clinical parameters and serum C-reactive protein (CRP) levels were evaluatedfor all patients at the baseline, 3 weeks, and 6 weeks. Results: Improved gingival index scores found in the test group as compared to the controlgroup were found to be statistically significant only after 3 weeks (P<0.001). In contrast,the decrease in the sulcus bleeding index and pocket depth scores was statistically highlysignificant in the test group as compared to the control group after 3 weeks and 6 weeks(P<0.001). However, reduced clinical attachment level and CRP scores, as reflected in thetest group as compared to the control group, were not found to be statistically significantafter both 3 weeks (P>0.05) and 6 weeks (P>0.05). Conclusions: The results of this clinical-biochemical study suggest that dietary supplementationwith herbal immunomodulatory agents may be a promising adjunct to SRP and mayaid in improving periodontal treatment outcomes.

      • SCIESCOPUSKCI등재

        Herbal anti-inflammatory immunomodulators as host modulators in chronic periodontitis patients: a randomised, double-blind, placebo-controlled, clinical trial

        Deore, Girish D.,Gurav, Abhijit N.,Patil, Rahul,Shete, Abhijeet R.,Naiktari, Ritam S.,Inamdar, Saurabh P. Korean Academy of Periodontology 2014 Journal of Periodontal & Implant Science Vol.44 No.2

        Purpose: Host modulatory therapy has been proposed as a treatment for periodontal diseases. A class of herbal medicines, known to be immunomodulators, alters the activity of immune function through the regulation of informational molecules such as cytokines. In the current study, we tested the hypothesis that herbal immunomodulator drugs act as an adjuvant to scaling and root planing (SRP) in alleviating periodontal inflammation by improving clinical and biochemical parameters. Methods: Sixty healthy subjects (30 in each group) with moderate and severe chronic periodontitis were enrolled in a double-blind, placebo-controlled, double-masked randomised controlled trial. The control group was treated with SRP and a placebo, whereas the test group was treated with SRP followed by dietary supplementation of Septilin for 3 weeks. Periodontal clinical parameters and serum C-reactive protein (CRP) levels were evaluated for all patients at the baseline, 3 weeks, and 6 weeks. Results: Improved gingival index scores found in the test group as compared to the control group were found to be statistically significant only after 3 weeks (P<0.001). In contrast, the decrease in the sulcus bleeding index and pocket depth scores was statistically highly significant in the test group as compared to the control group after 3 weeks and 6 weeks (P<0.001). However, reduced clinical attachment level and CRP scores, as reflected in the test group as compared to the control group, were not found to be statistically significant after both 3 weeks (P>0.05) and 6 weeks (P>0.05). Conclusions: The results of this clinical-biochemical study suggest that dietary supplementation with herbal immunomodulatory agents may be a promising adjunct to SRP and may aid in improving periodontal treatment outcomes.

      • SCISCIESCOPUS

        NO<sub>2</sub> sensing properties of porous fibrous reticulated WO<sub>3</sub> thin films

        Shendage, S.S.,Patil, V.L.,Patil, S.P.,Vanalakar, S.A.,Bhosale, J.L.,Kim, J.H.,Patil, P.S. ELSEVIER 2017 JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS Vol.125 No.-

        <P><B>Abstract</B></P> <P>In this work, the WO<SUB>3</SUB> thin films were synthesized onto glass substrates at 673K by simple and cost-effective spray pyrolysis technique for the NO<SUB>2</SUB> gas sensing. Moreover, the WO<SUB>3</SUB> thin film was synthesized as a function of different spray solution concentration. The structural and morphological results reveal the polycrystalline nature of WO<SUB>3</SUB> thin films with pure monoclinic phase having porous fibrous reticulate morphology. The optical band gaps of WO3 thin films were observed ∼2.73eV. Moreover, the activation energy in our WO<SUB>3</SUB> sample (0.368eV) is maximum than the theoretical value of activation energy (0.031eV). Due to the outstanding morphology and grater activation energy, the WO<SUB>3</SUB> thin films were used for NO<SUB>2</SUB> gas sensing. The gas sensing properties of the thin film sensor based on WO<SUB>3</SUB> thin films were studied in the range of 1–100ppm of the NO<SUB>2</SUB> at an operating temperature of 423K (or 150°C). The sensor exhibits better gas response around 5.75 for 5ppm of NO<SUB>2</SUB> gas as well as 84.75 for 100ppm NO<SUB>2</SUB> gas with better selectivity.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Porous reticulated fibrous morphology of WO<SUB>3</SUB> were synthesized via the simplistic chemical route. </LI> <LI> The nano-fibrous of WO<SUB>3</SUB> exhibited excellent and highly selective gas response ∼5.75 for 5ppm of NO<SUB>2</SUB> gas. </LI> <LI> The synthesis route and sensing behavior of as synthesized WO<SUB>3</SUB> revealed a promising candidate for fabricating low-consumption gas sensors. </LI> </UL> </P>

      • SCISCIESCOPUS

        Investigations on silver/polyaniline electrodes for electrochemical supercapacitors

        Patil, Dipali S.,Shaikh, J. S.,Pawar, S. A.,Devan, R. S.,Ma, Y. R.,Moholkar, A. V.,Kim, J. H.,Kalubarme, R. S.,Park, C. J.,Patil, P. S. The Royal Society of Chemistry 2012 Physical chemistry chemical physics Vol.14 No.34

        <P>Polyaniline (PANI) and silver doped polyaniline (Ag/PANI) thin films were deposited on stainless steel substrates by a dip coating technique. To study the effect of doping concentration of Ag on the specific capacitance of PANI the concentration of Ag was varied from 0.3 to 1.2 weight percent. Fourier transform-infrared and Fourier transform-Raman spectroscopy, and energy dispersion X-ray techniques were used for the phase identification and determination of the doping content in the PANI films, respectively. The surface morphology of the films was examined by Field Emission Scanning Electron Microscopy, which revealed a nanofiber like structure for PANI and nanofibers with bright spots of Ag particles for the Ag/PANI films. There was decrease in the room temperature electrical resistivity of the Ag/PANI films of the order of 10<SUP>2</SUP> with increasing Ag concentration. The supercapacitive behavior of the electrodes was tested in a three electrode system using 1.0 M H<SUB>2</SUB>SO<SUB>4</SUB> electrolyte. The specific capacitance increased from 285 F g<SUP>−1</SUP> (for PANI) to 512 F g<SUP>−1</SUP> for Ag/PANI at 0.9 weight percent doping of Ag, owing to the synergic effect of PANI and silver nanoparticles. This work demonstrates a simple strategy of improving the specific capacitance of polymer electrodes and may also be easily adopted for other dopants.</P> <P>Graphic Abstract</P><P>The presence of Ag nanoparticles on PANI nanofibers provides a least resistance path to electron transportation. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cp41757j'> </P>

      • SCISCIESCOPUS

        Compact nanoarchitectures of lead selenide via successive ionic layer adsorption and reaction towards optoelectronic devices

        Bhat, T. S.,Vanalakar, S. A.,Devan, R. S.,Mali, S. S.,Pawar, S. A.,Ma, Y. R.,Hong, C. K.,Kim, J. H.,Patil, P. S. Springer Science + Business Media 2016 Journal of materials science Materials in electron Vol.27 No.5

        <P>Thin films of Lead Selenide (PbSe) having compact nanoarchitectures were synthesized by a facile and cost-efficient successive ionic layer adsorption and reaction (SILAR) technique. The structural, morphological, optical and compositional properties were studied using X-ray diffraction (XRD), Field emission scanning electron microscopy (FESEM), Transmission electron microscopy (TEM), UV-vis spectrophotometer, and X-ray photoelectron spectroscopy (XPS) techniques. Moreover, the effect of SILAR cycles on the morphology of PbSe thin films was investigated. XRD patterns revealed the formation of crystalline PbSe with the cubic crystal structure. FESEM images show shape evolution from nanoparticulate to merged pyramidal-like structure with variation in size from similar to 200 to 430 nm. The optical direct band gap energy of PbSe were varies from 1.32 to 1.20 eV with the increase in deposition cycles. The HRTEM and SAED results show the crystalline nature of the sample which is in good agreement with the XRD. The electrical characterizations were performed in order to obtain the ohmic behavior in the metal-semiconductor interface. The deposited thin films show a good ohmic behavior.</P>

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