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Influence of scent on car driver stress: Taste in scents, difference o f reaction by sex
Kazuaki Onoue,Takahiro Wada,Shun’ichi Doi,Eiji Kobayashi,Masayuki Karaki,Nozomu Mori 대한인간공학회 2010 대한인간공학회 학술대회논문집 Vol.2010 No.5
Long term monotonous driving has often been found to decrease the driver’s arousal level and effect perception, cognition and judgment. In this study, seven kinds of scent were used as olfactory stimulation. The influence of scent on the driver’s psychosomatic state was examined using a fixed-based driving simulator by through biological measurements including electrocardiogram. Taste in scents is so individual that blood flow of brain activity is measured in order to estimate the reaction of scent on the subject. As for brain activity of olfactory cortex, the multi-channel near-infrared spectroscopy (MNIRS) has been shown to enable the evaluation of changes in hemodynamic. The MNIRS was also used to monitor the activity of the frontal cortex as mirrored by hemodynamic responses subjected to olfactory stimulation. The experiments were executed for several female and male subjects. The difference of reaction by sex is also observed.
Seunghee Hong,Seiya Harada,Kazuaki Onoue,Byungchan Min,Keisuke Suzuki,Shun'ichi Doi 대한인간공학회 2012 대한인간공학회 학술대회논문집 Vol.2012 No.5
A major cause of traffic accidents has been found in the human factors involved in driver's awareness during driving, and the effect of alarm was reported as the increase of awareness and the improving effect for property of perception, cognition and judgment of the driver. The arousal stimulus for driver by auditory-visual alert also affects to the physiological condition and the autonomic nervous system (ANS). Recent developments in multi near-infrared spectroscopy (MNIRS) have enabled the arousal level apparent with brain activity by measurement of hemoglobin concentrations as cerebral blood volume, as well as the ordinary biological signals like heart beats, finger plethysmogram and pulsation waves. In this study, the three kinds of auditory alert as pre-information, sound alert and voice guidance were used for adaptive assisting systems for the elderly driver and the influence of these alerts on the driver's psychosomatic state was examined using driving simulator for 30 minutes driving. Experiment was conducted with the subjects in a driving position as they were partially awakened by auditory-visual alert, repeatedly and measured their biological properties. As the results, after taking the effects of the adaptive assisting alert systems, the effect of arousal and awareness improvement was recognized in the subjects and the activation of cerebral blood volume was observed according to the amount of the stimulus and combination of awareness modal as auditory alert system.
Dietary L-Cysteine Inhibits D-Galactosamine-induced Acute Liver Injury in Rats
이슬기,한규호,Erina Yabuki,Yumi Nakamura,Sakura Kawakami,Ken-ichiro Shimada,Hirotake Onoue,Michihiro Fukushima 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.3
The effects of L-cysteine (1 and 2%) on the antioxidative system were examined in rats with Dgalactosamine (D-GalN)-induced injury. These rats showed increases in serum antioxidative enzyme and hepatic thiobarbituric acid reactive substances (TBARS) activities, with decreased hepatic/serum glutathione (GSH) levels and GSH-related enzyme activities. However, L-cysteine supplementation resulted in a decrease of hepatic TBARS levels, and increased catalase and serum GSH levels. The activities of serum enzymes in rats receiving 2% L-cysteine were significantly (p<0.05) lower than in D-GalN-injected group rats, and similar to levels in control group rats without acute liver injury. In addition, 2% L-cysteine increased the glutathione reductase activity and decreased the serum TBARS level in liver injury group rats. Dietary L-cysteine, especially at a 2% level, exerts a hepatoprotective effect by alteration of the GSH level and antioxidative enzyme activities.