Impairing Effects of Acute Glucose Overload on Calcium Homeostasis in Vascular Endothelial Cells

Masahiro Oike,Chiwaka Kimura 대한생리학회-대한약리학회 1998 The Korean Journal of Physiology & Pharmacology Vol.2 No.6

헤어짐의 인사말 ‘さようなら(sayonara)’에 대한 일본어모어화자 교육자의 사용의식-한국에 거주하는 일본어교육자에 대한 조사를 중심으로-

오이케신 ( Shin Oike ),이토타카오 ( Takao Ito ),곤유미 ( Yumi Kon ),미네자키도모코 ( Tomoko Minezaki ) 한국일어교육학회 2014 일본어교육연구 Vol.0 No.30

본 연구는 ‘헤어짐의 장면’에서 사용되는 일본어 인사말 지도와 관련하여, 현재 한국 내 일본어 교육 일선에서 활동하고 있는 일본어 교사의 사용 의식 경향을 파악하기 위한 목적으로 실시되었다. 구체적으로 본 연구에서는 일본어 모어화자 중 한국에 거주하는 일본어 교사 117명을 대상으로 헤어짐의 인사말 ‘さようなら(sayonara)’의 사용 의식에 대한 설문조사를 실시하였다. 이를 토대로 도출된 일본어 모어화자 교사의 ‘さようなら(sayonara)’ 사용 의식 결과는 다음과 같다. 첫째, ‘학생’과의 관계의 경우 ‘짧은 대화를 한 후에 헤어질 때’, ‘수업 종료 후 전원에게’, ‘교실을 나가는 개인에게’에 대한 응답 비율이 높게 나타났다. 둘째, ‘스스로 관계를 정리하고자 하는 상대방’과의 관계에서는 ‘전화로 대화할 때’ 및 ‘직접 대화할 때’에 대한 응답 비율이 높았다. 마지막으로 ‘고인(故人)’과의 관계의경우, ‘장례식에서 명복을 빌 때’의 상황에 대한 응답자의 비율이 높은 것으로 나타났다. 다음으로 분석 결과 ‘さようなら(sayonara)’ 사용 장면에 관한 자유 응답의 범주는 ‘영원한 이별 계열’과 ‘의례적인 이별 계열’로 분류되었다. 본 조사에서 설정한 ‘さようなら(sayonara)’ 사용 의식을 ‘관계-범주’로 분류한 결과는 다음과 같다. 첫째, ‘학생’과의 관계의 경우 ‘의례적인 이별 계열’에 해당되는 응답이 높았다. 둘째, ‘스스로 관계를 정리하고자 하는 상대방’ 및 ‘고인’과의 관계에서는 ‘영원한 이별 계열’에 해당되는 응답이 높게 나타났다. 아울러 본 연구에서는 ‘의례적인 이별 계열’ 중 ‘학생’과의 관계에서 나타나는 ‘さようなら(sayonara)’ 사용 의식의 경우 한국 거주 일본어 모어화자 교사가 받았던 자신의 과거 교육 환경이 영향을 미치고 있을 가능성이 있다는 함의를 도출할 수 있었다. 本硏究では、別れの場面でのあいさつ言葉を指導する上で、韓國での日本語敎育現場において實際に指導を行なっている日本語敎師自身の使用意識の傾向を知るため、日本語母語話者のうち韓國在住の日本語敎師117名を對象に、別れのあいさつ言葉「さようなら」の使用意識に對するアンケ一ト調査を實施した。その結果、「學生」との關係では「短い立ち話の後に別れる」「授業終了後全員に」「敎室を出る個人に」の場面、また「自分から關係を終わらせようとする人」との關係では、「電話で話す」「直接話す」場面において、「故人」との關係では「葬儀で冥福を祈る」場面において、「さようなら」を使用する意識を持つ回答者の割合が高かった。また自由回答の結果からは「永遠の別れ系」と「儀禮的な別れ系」の二つに分類された。さらに本調査で設定した「さようなら」を使用する意識を持つ回答者の割合が高い關係の中で、「學生」との關係では「儀禮的な別れ系」に該當し、「自分から關係を終わらせようとする人」との關係および「故人」との關係では「永遠の別れ系」に該當する回答が見られた。「永遠の別れ系」については從來の先行硏究でも言及されてきたが、特に「學生」との關係における「儀禮的な別れ系」については、日本語母語話者である韓國在住の日本語敎師自身の受けた過去の敎育環境が、その後の使用意識に影響している可能性があるという觀点が導き出された。

Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development.

Kubota, Yoshiaki,Oike, Yuichi,Satoh, Shinya,Tabata, Yoko,Niikura, Yuichi,Morisada, Tohru,Akao, Masaki,Urano, Takashi,Ito, Yasuhiro,Miyamoto, Takeshi,Nagai, Norihiro,Koh, Gou Young,Watanabe, Sumiko,Sud National Academy of Sciences 2005 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.102 No.38

<P>Angiopoietin-like protein (Angptl) 1 and Angptl2, which are considered orphan ligands, are highly homologous, particularly in the fibrinogen-like domain containing the putative receptor binding site. This similarity suggests potentially cooperative functions between the two proteins. In this report, the function of Angptl1 and Angptl2 is analyzed by using morpholino antisense technology in zebrafish. Knockdown of both Angptl1 and Angptl2 produced severe vascular defects due to increased apoptosis of endothelial cells at the sprouting stage. In vitro studies showed that Angptl1 and Angptl2 have antiapoptotic activities through the phosphatidylinositol 3-kinase/Akt pathway, and coinjection of constitutively active Akt/protein kinase B mRNA rescued impaired vascular development seen in double knockdown embryos. These results provide a physiological demonstration of the cooperative interaction of Angptl1 and Angptl2 in endothelial cells through phosphatidylinositol 3-kinase/Akt mediated antiapoptotic activities.</P>

現代高校生の語彙表現と心象風景の一斷面 -「高校生川柳」における語彙と主題を中心に-

( Ito Takao ),( Oike Shin ) 고려대학교 일본학연구센터 2015 일본연구 Vol.23 No.-

本稿は「高校生川柳」を對象として、「語彙」と「主題」という觀点から、今を生きる日本の高校生の言語表現の特徵を分析し、彼らの胸の內に映じた心象風景の一端を描き出そうとした。その結果、まず語彙という觀点では「母」が最も多く用いられており、そのほか、家族と自分に觀する語彙、季節.天候に關する語彙、家族以外の身近な人ケに關する語彙、情意的語彙、言語表現に關する語彙など、多樣な語彙に樣ケな意味や心情を託し、巧みな比喩や諷刺, ユ-モアなどを用いて、自らの心の懊にある世界觀を見事に表現していた。また、主題という觀点では、勉强.受驗に關する內容が最も多くを占めたが、そのほかにも學校生活や家族との關係、日常生活から社會問題におよぶまで、多岐にわたる分野の事柄を題材としており、彼らの關心の幅廣さが表れていた。そして、作品全般を通して、樣ケな現實の課題に腦みながらも、夢を持って一步一布、懸命に生きる日本の高校生の樣子が、生き生きと描かれていた。 The aim of this study was to analyze the characteristics of the vocabulary used by Japanese high school students in modern society, centering on “High School Students’ senryu,” and imagined scenery. With respect to vocabulary, the results of the analysis showed that the most commonly used word was “mother,” and other frequently used vocabulary included words that were related to one’s family and oneself, weather and seasons, people around oneself other than one’s family, as well as sentimental words and words related to linguistic expressions. Students used diverse vocabulary to convey various meanings and sentiments and even used figure of speech, satire, and humor to express their worldviews. The most common theme, on the other hand, was related to studying and college entrance. Other common themes were school life, family relationships, and social issues. A wide range of themes were touched upon, showing that the students had broad interests. In all of the works, it was revealed that the students were striving toward their dreams despite the various real challenges and issues they were dealing with.

동아시아 지진활동의 시간적 특성과 起震응력장과의 관계

경재복,Kazuo Oike 대한지질학회 1995 대한지질학회 학술대회 Vol.1995 No.

Nurses’ Work-family Conflict and Sex Role Orientation

Yoshiko Yamaguchi,Hiroko Harada,Miyako Oike 한국간호과학회 2015 한국간호과학회 학술대회 Vol.2015 No.10

日本人觀光客が「謝罪がない」と感じた接客場面における不滿の種類と韓國人接客者の對應 -韓國旅行情報サイトの投稿をもとに-

이취조야향 ( Sayaka Ibuki ),대지삼 ( Shin Oike ),근유미 ( Yuumi Kon ),중촌유리 ( Yuri Nakamura ) 한국일어교육학회 2015 일본어교육연구 Vol.0 No.33

本稿では、韓國旅行情報サイトの投稿から、日本人觀光客が不滿を抱いたにもかかわらず「謝罪がない」と感じた事例を抽出し、「日本人觀光客の不滿の種類」「韓國人接客者の對應の仕方」「これら2の關連性」の3點を考察した。その結果、「不滿の種類」は10種類、「對應の仕方」は9種類に分類できた。不滿の種類の中で最も多かったのは「間違い系」、對應の仕方の中で最も多かったのは「對處せず無反應」であった。また、すべての不滿の種類において、對處の有無にかかわらず「無反應」という反應が最も多く見られた。そこから、「無反應」という槪念で壹括りにされている對應には、①日本人觀光客が不滿を抱いていることに氣づいていないため反應がない、②不滿には氣づいているが責任回避のために反應を示さずにいる、③韓國人接客者自身は表情や身ぶりで何らかの反應を示しているつもりであるが日本人關光客にはそれが傳わっていない、などの複數の原因が混在している可能性が考えられた。さらに、「間違い系」「危ない系」「食品衛生系」「施設の不備系」という不滿の種類では「對處有り」という對應の仕方の割合が比較的多く、「汚れる系」「放置系」「無禮系」「自分勝手系」では「對處無し」の割合が比較的多いことが確認できた。そこから、韓國人接客者は「目的達成指向性」が强く、そのため「取り返しがつく」場合は對處はするものの謝罪はせず、「取り返しがつかない」場合には對處も謝罪もしない傾向があるのではないかということが考えられた。 This research studied three points, e.g. ``dissatisfaction types of Japanese tourists``, ``the way of Korean receptionists`` response`, and ``correlation between the two``, by selecting the cases in the comments in the Korean Travel Information Site regarding Japanese tourists felt ``No apology``, nevertheless they had dissatisfaction. As the result, ``types of dissatisfaction`` was classified into 10, and ``the way of response`` was classified into 9. The majority of dissatisfaction types appeared ‘error group’, and the majority of the way of response appeared ‘no response without handling’. Also, in all types of dissatisfaction, response of ``no response`` appeared the most, regardless of handling. Here, several possibilities were considered to occur in respect of the response combined by ``no response``, e.g. ①No response since they did not recognize the Japanese tourists had dissatisfaction, ②The recognized dissatisfaction, however they did not respond in order to evade responsibility, ③Korean receptionists thought they showed any response through their look or gesture, however that was not perceived by the Japanese tourists, etc. Also, while the way of response, ``responded`` appeared relatively high, among the four types of dissatisfaction in ``error group``, ``risk group``, ``food hygiene group``, ``incomplete facility group`` in four dissatisfaction types, on the contrary, ``no response`` ratio appeared relatively high in ``dirtiness group``, ``negligence group``, ``rudeness group``, ``abandonment group``. Here, the researcher considered that Korean receptionists probably respond to the case when they ``could undo``, since they had strong ``tendency of goal achieving(目的達成指向性)’, however they do not apologize, while they do not respond nor apologize in case when they ``could not undo``.

Does physiotherapy after rotator cuff repair require supervision by a physical therapist?: a meta-analysis

Masaki Karasuyama,Masafumi Gotoh,Takuya Oike,Kenichi Nishie,Manaka Shibuya,Hidehiro Nakamura,Hiroki Ohzono,Junichi Kawakami 대한견주관절의학회 2023 대한견주관절의학회지 Vol.26 No.3

Background: A supervised physiotherapy program (SPP) is a standard regimen after surgical rotator cuff repair (RCR); however, the effect of a home-based exercise program (HEP), as an alternative, on postoperative functional recovery remains unclear. Therefore, the purpose of this meta-analysis was to compare the functional effects of SPP and HEP after RCR. Methods: We searched electronic databases including Central, Medline, and Embase in April 2022. The primary outcomes included the Constant score, American Shoulder and Elbow Surgeons score, University of California Los Angeles shoulder score, and pain score. Secondary outcomes included range of motion, muscle strength, retear rate, and patient satisfaction rate. A meta-analysis using random-effects models was performed on the pooled results to determine the significance. Results: The initial database search yielded 848 records, five of which met our criteria. Variables at 3 months after surgery were successfully analyzed, including the Constant score (mean difference, −8.51 points; 95% confidence interval [CI], −32.72 to 15.69; P=0.49) and pain score (mean difference, 0.02 cm; 95% CI, −2.29 to 2.33; P=0.99). There were no significant differences between the SPP and HEP. Other variables were not analyzed owing to the lack of data. Conclusions: Our data showed no significant differences between SSP and HEP with regard to the Constant and pain scores at 3 months after RCR. These results suggest that HEP may be an alternative regimen after RCR.

울산단층 중앙부의 단층 노두와 대지진 발생의 지형적 증거

경재복,김성균,조화룡,Okada A,Watanabe M,Suzuki Y.,Oike K. 대한지질학회 1995 대한지질학회 학술대회 Vol.1995 No.

HFA-PEFF scores: prognostic value in heart failure with preserved left ventricular ejection fraction

( Koichi Egashira ),( Daisuke Sueta ),( Takashi Komorita ),( Eiichiro Yamamoto ),( Hiroki Usuku ),( Takanori Tokitsu ),( Koichiro Fujisue ),( Taiki Nishihara ),( Fumi Oike ),( Masafumi Takae ),( Shins 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.1

Background/Aims: The Heart Failure Association (HFA)-PEFF score is recognized as a simple method to diagnose heart failure (HF) with preserved ejection fraction (HFpEF). This study aimed to evaluate the relationship between HFA-PEFF scores and cardiovascular outcomes in HFpEF patients. Methods: A total of 502 consecutive HFpEF patients were prospectively observed for up to 1,500 days. Cardiovascular outcomes were compared between two groups of patients, defined by their HFA-PEFF scores: those who scored 2-4 (the intermediate-score group) and those who scored 5-6 group (the high-score group). Overall, 236 cardiovascular events were observed during the follow-up period (median, 1,159 days). Results: Kaplan-Meier analysis showed that there were significant differences in composite cardiovascular events and HF-related events between the intermediate-score group and the high-score group (p = 0.003 and p < 0.001, respectively). Multivariate Cox proportional hazards analysis showed that the HFA-PEFF scores significantly predicted future HF-related events (hazard ratio, 1.66; 95% confidence interval [CI], 1.11 to 2.50; p = 0.014); receiver operating characteristic analysis confirmed this relationship (area under the curve, 0.633; 95% CI, 0.574 to 0.692; p < 0.001). The cutoff HFA-PEFF score for the identification of HF-related events was 4.5. Decision curve analysis revealed that combining the HFA-PEFF score with conventional prognostic factors improved the prediction of HF-related events. Conclusions: HFA-PEFF scores may be useful for predicting HF-related events in HFpEF patients.