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Tran, T. H.,Nguyen, T. D.,Nguyen, H.,Nguyen, H. T.,Kim, J. O.,Yong, C. S.,Nguyen, C. N. Springer Science + Business Media 2016 Archives of Pharmacal Research Vol.39 No.5
<P>Poly(d,l-lactic-co-glycolic acid) (PLGA) nanoparticles with negative surface charge were reversed to positive by cationic surfactant-DDAB before being coated with an anionic polymer, hyaluronic acid, to improve their site-specific intracellular delivery against CD44 receptor overexpressing cancer cells. Incorporating artesunate (ART)-a promising anticancer drug into PLGA/HA nanoparticles, is expected not only to overcome its poor aqueous solubility and stability but also enhance the activities. The obtained particles were characterized by dynamic light scattering, zeta potential measurements, and transmission electron microscopy (TEM). Cancer cell internalization of the NPs was evaluated by flow cytometry and cytotoxicity of the NPs was tested by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay. PLGA/HA nanoparticles showed greater extent of cellular uptake to SCC-7 and MCF-7 cells, indicating their affinity with CD44 receptor-mediated endocytosis. Almost 60 % of ART was released into the outer media after 48 h. In vitro fluorescence sorting demonstrated that PLGA/HA had highly efficient targeting and accumulation into CD44 receptor overexpression cells. The significant reduction in cell viability as well as greater induction of apoptosis suggested a potential in anticancer therapy of ART loaded PLGA/HA.</P>
Nguyen, D.H.,Tran, H.N.,Yun, H.M.,Kim, I.H.,Plaizier, J. Canadian Science Publishing 2018 Canadian journal of animal science Vol.98 No.2
<P> A total of 480 one-day-old male Ross 308 broilers with an average initial body weight (BW) of 42 ± 1 g was randomly divided into four treatments (8 replicates/treatment, 15 birds/replicate) by their BW to evaluate the influence of a cocktail of protease and xylanase in different energy density of corn- and soybean-meal-based diet on broilers. This experiment lasted for 35 d and there were two phases; starter (1-18 d) and finisher (19-35 d). The experiment was a 2 × 2 factorial arrangement with two levels of metabolizable energy and the cocktail enzyme with 200 mg of protease kg<SUP>−1</SUP> diet and 100 FXU xylanase kg<SUP>−1</SUP> diet. Both high-nutrient density and cocktail enzyme supplementation increased (P @@<@@ 0.05) the body weight gain (BWG) during day 1-18 and day 1-35 as well as dry matter retention on day 35. Broilers fed the high-nutrient-density diets had higher (P @@<@@ 0.05) energy retention on day 35 and relative breast muscle weight. Broilers fed the cocktail enzyme diets significantly increased nitrogen (N) retention and decreased the levels of ammonia (NH3) and hydrogen sulphide (H2S) emission. In conclusion, dietary supplementation of the cocktail enzyme component improved BWG, N retention, and reduced excreta noxious gas emission in broilers. </P>
Distributed Scheduling Scheme for Optimal Performance in Wireless Networks
Nguyen H. Tran,Choong Seon Hong 한국정보과학회 2011 한국정보과학회 학술발표논문집 Vol.38 No.1D
We propose a randomized distributed scheduling algorithm which can achieve the optimal throughput under the general interference model. The proposed algorithm is analyzed to show an attractive performance in that it can return a maximal schedule with high probability and has a low time-complexity. We also provide the simulation results to validate performance analysis of our algorithm.
Fair Scheduling for Throughput Improvement in Wireless Mesh Networks
( Nguyen H. Tran ),( Choong Seon Hong ) 한국정보처리학회 2007 한국정보처리학회 학술대회논문집 Vol.14 No.1
Throughput improvement problem in wireless mesh network can be alleviated by equipped mesh router with multiple radios tuned into orthogonal channels. However, some links on the same channel also can be activated concurrently if the Signal-to-Noise and Interference Ratio (SNIR) at their receiver endpoints is not lower than the threshold. We propose a greedy algorithm to investigate the problem of how to schedule a set of feasible transmission under physical interference model by using the spatial time-division multiple-access (STDMA) scheme. We also consider the fairness in scheduling to prevent some border nodes from starvation. We evaluate our algorithms through extensive simulation and the results show that our algorithms can achieve better aggregate throughput and fairness performance than 802.11 standard.
Optimal Pricing Effect on Equilibrium Behaviors of Delay-Sensitive Users in Cognitive Radio Networks
Tran, Nguyen H.,Choong Seon Hong,Zhu Han,Sungwon Lee IEEE 2013 IEEE journal on selected areas in communications Vol.31 No.11
<P>This paper studies price-based spectrum access control in cognitive radio networks, which characterizes network operators' service provisions to delay-sensitive secondary users (SUs) via pricing strategies. Based on the two paradigms of shared-use and exclusive-use dynamic spectrum access (DSA), we examine three network scenarios corresponding to three types of secondary markets. In the first monopoly market with one operator using opportunistic shared-use DSA, we study the operator's pricing effect on the equilibrium behaviors of self-optimizing SUs in a queueing system. We provide a queueing delay analysis with the general distributions of the SU service time and PU traffic using the renewal theory. In terms of SUs, we show that there exists a unique Nash equilibrium in a non-cooperative game where SUs are players employing individual optimal strategies. We also provide a sufficient condition and iteraIntive algorithms for equilibrium convergence. In terms of operators, two pricing mechanisms are proposed with different goals: revenue maximization and social welfare maximization. In the second monopoly market, an operator exploiting exclusive-use DSA has many channels that will be allocated separately to each entering SU. We also analyze the pricing effect on the equilibrium behaviors of the SUs and the revenue-optimal and socially-optimal pricing strategies of the operator in this market. In the third duopoly market, we study a price competition between two operators employing shared-use and exclusive-use DSA, respectively, as a two-stage Stackelberg game. Using a backward induction method, we show that there exists a unique equilibrium for this game and investigate the equilibrium convergence.</P>
Nguyen, V.H.,Tran, T.H.,Shim, J.J. Elsevier 2014 Materials Science and Engineering C Vol.44 No.-
Conducting poly(o-phenylenediamine) (POPD)/graphene oxide (GO) composites were prepared using a facile and efficient method involving the in-situ polymerization of OPD in the presence of GO in an aqueous medium. Copper sulfate was used as an oxidative initiator for the polymerization of OPD. Scanning electron microscopy and transmission electron microscopy images showed that POPD microfibrils were formed and distributed relatively uniformly with GO sheets in the obtained composites. X-ray diffraction results revealed the highly crystal structure of POPD. This composite exhibited good catalytic activity and stability. These results highlight the potential applications of POPD/GO composites as excellent electrochemical sensors. The composites were used to modify glass carbon electrodes for the chemical detection of hydrogen peroxide in aqueous media.
Joint Pricing and Load Balancing for Cognitive Spectrum Access: Non-Cooperation Versus Cooperation
Tran, Nguyen H.,Long Bao Le,Shaolei Ren,Zhu Han,Choong Seon Hong IEEE 2015 IEEE journal on selected areas in communications Vol.33 No.5
<P>In the dynamic spectrum access (DSA), pricing is an efficient approach providing economic incentives for operators, whereas load balancing yields congestion-avoidance incentives for secondary users (SUs). Despite complexities of 1) the couplings among pricing, load balancing, and SUs' spectrum access decision, and 2) the heterogeneity of primary users' traffic and SUs classes/types, we tackle the joint load balancing and pricing problem to maximize operators' revenue in two cognitive radio markets: monopoly and duopoly. For the monopoly market, we first show there exists a unique SUs' equilibrium arrival rate to the monopolist's channels. We then show that the joint problem can be solved efficiently by exploiting its convex structure. For the duopoly market, we first characterize a unique SUs' equilibrium arrival rate to two operators employing different DSA approaches. When two operators are noncooperative, we show that there exists a unique Nash equilibrium for each operator's revenue. When they are cooperative, we show that the social revenue optimization can achieve a unique optimal solution. Using the Nash bargaining framework, we also present a sharing contract that determines the optimal fraction of the social revenue for each operator. In both markets, we propose two algorithms that can find the largest SU class supportable by the operators.</P>