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Nguyen Thu Hien,Nguyen Duc Quan,Kim Lien Nguyen Thi,Thi Thanh Ngan Nguyen,Nguyen Thi Phuong Mai,Tran Ngoc Dung,Nguyen Huy Hoang 한국유전학회 2023 Genes & Genomics Vol.45 No.4
Background Androgens and androgen receptor (AR) are critical regulators of the masculinization process in male sexual development. The absence of a functioning AR results in the development of the androgen insensitivity syndrome (AIS), a rare disorder of sexual development (DSD) characterized by the external genitalia feminization, gynecomastia, and impaired spermatogenesis. Objective To determine the AR gene mutations associated with male DSD in four unrelated Vietnamese patients. Methods To detect the disease-causing mutations, whole exome sequencing (WES) was performed on four patients diagnosed with AIS. Sanger sequencing was then used for validation of the identified mutations. Finally, 12 web-based tools, three-dimensional protein modeling software, and the guidelines issued by the American College of Medical Genetics and Genomics were used to assess the potential pathogenicity of these mutations. Results Four distinct novel mutations, namely c.1834T > A (p.Cys612Ser), c.2122 C > G (p.Leu708Val), c.2630T > G (p.Phe877Cys), and c.2641 C > A (p.Leu881Met) in the AR gene, were identified in four AIS patients using WES. The in silico analysis results revealed that the Cys612, Leu708, Phe877, and Leu881 sites are important for an appropriate response to androgens of the AR, and mutation at these sites can have adverse effects on the AR functions, androgen–AR interaction, and AR signaling pathway. Conclusions WES and in silico analyses strongly suggested that four novel AR mutations are pathogenic and have led to the development of AIS in the four Vietnamese patients under consideration.
The Impact of Cash Flow Statement on Lending Decision of Commercial Banks: Evidence from Vietnam
Dung Duc NGUYEN,Anh Huu NGUYEN 한국유통과학회 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.6
The paper investigates the impact of the statement of cash flows of listed companies on lending decisions of commercial banks in the context of Vietnam. Survey data for the research were collected from 160 credit officers of Vietnamese commercial banks for short-term and long-term lending decisions, whether the cash flow statement includes complete information or has a lack of information. The cash flow statement, in which the information on the cash flow is completely contrary to the profit information on the income statement is examined. This paper employed T-tests to address the research issues in a market considered to be ineffective, like Vietnam. The research results show: (1) the information on the cash flow statement affects both the short-term and long-term lending decisions of credit officers, and (2) the lack of information on the cash flow statement in both cases of positive and negative profits affects the comfort and confidence of credit officers in making decisions. The research findings also indicate that cash flow statements are important for lending decisions of credit institutions in Vietnam. Therefore, this paper provides a new insight to managers on how to improve the quality of cash flow statement to meet the needs of lenders.
Carbon-Nanotube Growth over Iron Nanoparticles Formed on CaCO3 Support by Using Hydrogen Reduction
Nguyen Duc Dung,Nguyen Van Chuc,Ngo Thi Thanh Tam,Nguyen Hong Quang,Phan Hong Khoi,Phan Ngoc Minh 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.5
Carbon nanotubes (CNTs) were grown by chemical vapor deposition on a mixture of iron salt and CaCO3. Salt mixtures of Fe(NO₃)₃9H₂O/CaCO₃ and FeCl₃6H₂O/CaCO₃ with various Fe weight contents were used as catalysts for growing the CNTs. A scanning electron microscope study revealed that the CNTs were densely grown on the Fe(NO₃)₃9H₂O/CaCO₃ catalyst containing 5 wt.% Fe. The effect of growth temperature on the segregation of Fe nanoparticles formed by hydrogen reduction is discussed. The result shows that 800 ℃ is the optimal temperature for the formation of Fe nanoparticles over which CNTs grow with the highest yield of 78.61 %. A raman spectroscope and a scanning transmission electron microscope were utilized to characterize the multiwall structure of the CNTs. The 92.16 % purity of the CNTs was determined by using thermal gravimetric analysis. Carbon nanotubes (CNTs) were grown by chemical vapor deposition on a mixture of iron salt and CaCO3. Salt mixtures of Fe(NO₃)₃9H₂O/CaCO₃ and FeCl₃6H₂O/CaCO₃ with various Fe weight contents were used as catalysts for growing the CNTs. A scanning electron microscope study revealed that the CNTs were densely grown on the Fe(NO₃)₃9H₂O/CaCO₃ catalyst containing 5 wt.% Fe. The effect of growth temperature on the segregation of Fe nanoparticles formed by hydrogen reduction is discussed. The result shows that 800 ℃ is the optimal temperature for the formation of Fe nanoparticles over which CNTs grow with the highest yield of 78.61 %. A raman spectroscope and a scanning transmission electron microscope were utilized to characterize the multiwall structure of the CNTs. The 92.16 % purity of the CNTs was determined by using thermal gravimetric analysis.
NGUYEN, Dung Duc,NGUYEN, Cong Van Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.5
The paper examines the impact of information about cash flow from operating activities of firms listed on Vietnam's stock market to the decision making of individual investors. Data were collected from interviews with 160 individual investors about their investment decisions based on information on profit growth and cash flow growth from operating activities. T-test was conducted to research on Vietnam's stock market - a market considered as information that is not really public, transparent and ineffective. The research results show that: (1) investors do not care about cash flow from operating activities when making investment decisions if the company's profits grow positively, (2) information about cash flow from operating activities only affects the decisions of individual investors once profit growth is negative, and (3) conflicting information between profit growth and cash flow growth from business activities significantly affects the confidence and comfort of investors in Vietnam's stock market when they make investment decisions. Then, the study points out the mistake of investors when making investment decisions, and offers recommendations to investors when making investment decisions, not only concerned with profit growth, but also paying special attention to cash flow growth, especially cash flow from the company's business operations.
The Impact of Methods of Presenting Cash Flow Statement on Loan Decision: Evidence from Vietnam
NGUYEN, Dung Duc Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.8
The paper aims to investigate the impact of presenting statements of cash flow using the direct method and the indirect method on loan decision by credit officers at Vietnamese banks. The data was collected from 150 credit officers of commercial banks in Vietnam based on the questionnaire about making loan decision when the cash flow statement is presented in different methods, namely, direct and indirect methods. This research uses T-tests to check whether using the direct or indirect method affects the accurate calculation of loan criteria, affects the loan decision by credit officers, and compare these two methods in the aspects of information provision. The research has pointed out that: 1) the direct method helps the calculation of indicators related to loans more accurately; 2) credit officers say that, while the direct method of presenting cash flow statement provides clearer information, the use of either the direct method or the indirect method does not affect the banks' loan decision. Since then, the author recommends that cash flow statements should be provided with information in a direct method to present the information needed for loan decision more accurately so as to improve the quality of cash flow statement.
Multiple-constraint variational framework and image restoration problems
Duc Dung Nguyen,Jae Wook Jeon IET 2015 IET image processing Vol.9 No.6
<P>In this study, an advanced variational model is presented for problem modelling in computer vision and image processing. The proposed model allows for the definition of multiple constraints in data fidelity, which has not been considered in previous state-of-the-art methods. With this definition, the model is more robust and flexible with regard to problem modelling. Two algorithms are introduced to solve the optimisation problems: one for the vector domain and the other for the frequency domain. The issue of multiple <I>L</I><SUP>1</SUP>-norms in the data fidelity term is resolved with these algorithms; this remained unsolved in previous research because of the difficulty with optimisation. The proposed model is demonstrated through two problems in image processing: image denoising and image deblurring. The results indicate that, compared to previous methods, images of high visual quality were both produced and recovered when using the proposed model. In addition, good and stable results in real-world images were yielded by the proposed model, which indicates vast potential for practical uses.</P>
QUÁ TRÌNH VÀ KINH NGHIỆM CỦA VIỆT NAM TRONG VIỆC TẠO LẬP THỊ TRƯỜNG VỐN SAU KHI THỐNG NHẤT
Nguyen Duc Minh,Nguyen Thu Dung 아주대학교 법학연구소 2016 아주법학 Vol.10 No.1
Có nhiều tiêu chí để phân loại thị trường vốn. Ở Việt Nam đa số ý kiến quan niệm thị trường vốn gồm 3 yếu tố cấu thành là thị trường chứng khoán, thị trường trái phiếu và thị trường tín dụng trung hạn, dài hạn. Bài viết dưới đây tập trung phân tích quá trình hình thành và phát triển của thị trường vốn ở Việt Nam sau khi thống nhất đất nước và đưa ra một số nhận xét và đánh giá.