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송낭희,김대현,Nang Hee Song,Dae Hyun Kim 대한안과학회 2013 대한안과학회지 Vol.54 No.2
Purpose: To compare the clinical features according to the presence of anisometropia in refractive accommodative esotropia patients. Methods: Forty-five refractive accommodative esotropia patients were divided into 2 groups : patients who had anisometropia of more than 1.00D (anisometropia group), and patients who had anisometropia of less than 1.00D (isometropia group). Age at onset, age when glasses were first worn, the initial and final angle of esotropia with or without hyperopic correction, the recovery time to orthophoria after hyperopic correction, the degree of stereoacuity and the frequency of amblyopia, the prevalence of deterioration, and the ratio of accommodative-convergence to accommodation were retrospectively reviewed. Results: There were no statistical differences between the 2 groups in the frequency of amblyopia, the prevalence of deterioration, and the ratio of accommodative-convergence to accommodation at the initial and final visit. The angles of deviation with hyperopic correction at the 1-month follow-up visit in the anisometropia group and the isometropia group were 8.80 ± 5.63 PD for near, 8.67 ± 5.42 PD for distance, and 4.54 ± 6.59 PD for near 5.19 ± 6.7 PD for distance, respectively; the difference was statistically significant (p = 0.042). The recovery time to orthophoria after hyperopic correction in patients associated with anisometropia was 2.20 ± 1.01 months, significantly longer than 1.47 ± 0.86 months in patients associated with isometropia (p = 0.017). Conclusions: In refractive accommodative esotropia patients associated with anisometropia, the recovery time to orthophoria after hyperopic correction was significantly prolonged but there were no statistical differences in other clinical manifestations.
송낭희,고재웅,Nang Hee Song,Jae Woong Koh 대한안과학회 2012 대한안과학회지 Vol.53 No.11
Purpose: To investigate the regional characteristics and the factors that influence final visual acuity in corneal laceration and use the results for prevention and treatment of corneal laceration. Methods: Sixty-eight patients who visited the Chosun University Medical Center from January 1, 2006 to December 31, 2010 were retrospectively surveyed. The incidence of corneal laceration, sex, age, monthly and seasonal distribution, cause, site and length of corneal laceration, secondary operation, complications, and ocular trauma score were reviewed statistically. In additional, the factors influencing visual prognosis were investigated. Results: The incidence was more common in males (94.1%) and in the 6th-decade of life (29.4%). The corneal laceration was more common in the summer (38.2%) and in September (26.5%) and the most common cause was stone (39.7%) and metal (35.3%), respectively. The corneal laceration tended to occur at the corneal center. The most common first operation was primary closure (81.9%), and the secondary operation was most often performed due to a traumatic cataract (32.1%). The factors that significantly influenced the final visual acuity were initial visual acuity, length and site of laceration, and secondary operation. Conclusions: The present survey investigated the regional characteristics and important factors influencing final visual acuity. Results show initial visual acuity, the length and site of laceration, and the secondary operation significantly influenced final visual acuity.
프로프라놀롤(Propranolol) 단독 사용에 의한 안와 모세혈관종 치료 1예
송낭희,김대현,Nang Hee Song,MD,Dae Hyun Kim,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.4
Purpose: To report a case of periorbital infantile capillary hemangioma treated with propranolol as a single therapy. Case summary: A 3-month-old girl with a growing red-purple mass on the right lower eyelid visited our clinic. The patient was diagnosed with capillary hemagioma by imaging studies. The mass had grown rapidly, and the visual axis was obscured in the follow-up. Oral propranolol therapy was initiated at a starting dose of 0.17 mg/kg at 8-hour intervals. After 2 doses, the propranolol was doubled, and after another 2 doses, the daily dose of 0.67 mg/kg divided into 3 was maintained. Three days after the initiation of the treatment, the color of the hemangioma had changed from red-purple to light purple, and the hemangioma had softened. The hemangioma continued to respond well with no side effects in the following 10 months. Conclusions: The authors suggest that oral propranolol treatment as a possibility of an effective and safe option for the vision- threatening periorbital capillary hemangioma as a single therapy. J Korean Ophthalmol Soc 2012;53(4):607-611
Case Reports : Achromobacter xylosoxidans Keratitis after Contact Lens Usage
( Jung Hyun Park ),( Nang Hee Song ),( Jae Woong Koh ) 대한안과학회 2012 Korean Journal of Ophthalmology Vol.26 No.1
To report on Achromobacter xylosoxidans keratitis in two healthy patients who had worn contact lenses foran extended period of time. A 36-year-old female and a 21-year-old female visited our hospital with ocular pain and blurred vision. Both patients had a history of wearing soft contact lenses for over fve years with occasional overnight wear. At the initial presentation, a slit lamp examination revealed corneal stromal infiltrations and epithelial defects with peripheral neovascularization in both patients. Microbiological examinations were performed from samples of corneal scrapings, contact lenses, contact lens cases, and solution. The culture resulting from the samples taken from the contact lenses, contact lens cases, and solution were all positive for Achromobacter xylosoxidans. Confrming that the direct cause of the keratitis was the contact lenses, the frst patient was prescribed ceftazidime and amikacin drops sensitive to Achromobacter xylosoxidans. The second patient was treated with 0.3% gatifoxacin and fortifed tobramycin drops. After treatment, the corneal epithelial defects were completely healed, and subepithelial corneal opacity was observed. Two cases of Achromobacter xylosoxidans keratitis were reported in healthy young females who wore soft contact lenses. Achromobacter xylosoxidans should be considered a rare but potentially harmful pathogen for lens-induced keratitis in healthy hosts.
흰점박이꽃무지에 발생하는 병원성 곰팡이 Metarhizium anisopliae에 대한 옻나무 추출액의 항진균 효과
김낭희,송명하,김은선,김용순,박관호,김선영,Kim, Nang-Hee,Song, Myung-Ha,Kim, Eunsun,Kim, Yongsoon,Park, Kwan-Ho,Kim, Sunyoung 한국하천호수학회 2020 생태와 환경 Vol.53 No.4
흰점박이꽃무지(Protaetia brevitarsis) 유충은 동아시아에서 식용 및 약용으로 널리 사용되고 있다. 흰점박이꽃무지 수요 증가로 인해 유충의 대량 사육 방법이 필요하지만 좁은 공간에서 대량으로 유충을 사육할 경우 곤충 병원성 질병 감염에 취약해진다. Metarhizium anisopliae는 흰점박이꽃무지 유충에 치명적인 곤충 병원성 곰팡이 중 하나이다. 이를 저해하기 위해 항진균 성분이 함유된 옻나무(Rhus verniciflua Stokes) 추출액을 첨가하였고, 연구 결과 1% 옻나무 추출액을 첨가한 경우 녹강균에 의한 유충의 치사율이 유의미하게 낮았다. 또한 일반톱밥을 급여한 대조구에 비해 옻나무 추출액 처리구에서 유충의 무게가 더 무거웠고 유충 기간이 짧아지는 것을 확인하였다. 따라서 이 연구를 통해 곤충 병원성 곰팡이에 대한 옻나무 추출액의 항진균 효과를 확인할 수 있었으며 흰점박이꽃무지 유충 사육 시 옻나무 추출액을 첨가하여 급여한다면 병원성 곰팡이에 의한 유충의 치사율을 낮추고 증체량을 높이는 데 효과가 있을 것이다. The white-spotted flower chafer (Protaetia brevitarsis) larva is one of the insects widely-used for edible and medicinal purposes in Eastern Asia. As a result of increasing demand for P. brevitarsis, massrearing systems in domestic farms have become necessary. However, the mass-rearing of larvae under confined rearing conditions could provide conditions unsuitable for preventing entomopathogenic diseases. Metarhizium anisopliae is the strongest fatal entomopathogenic fungus against P. brevitarsis. For inhibition of M. anisopliae, we used a Rhus verniciflua Stokes extract that has antifungal components. We investigated the inhibitory effect of the R. verniciflua extract at 1%, 5%, and 10% concentrations. The results showed that a 1% R. verniciflua extract added to sawdust produced a significantly low P. brevitarsis mortality rate. Moreover, extract-treated groups were heavier and had a shorter larval period than those of the untreated group. Consequently, we suggest that using an R. verniciflua extract can reduce the P. brevitarsis fatality rate from entomopathogenic fungi (e.g. M. anisopliae), resulting in more effective mass-rearing systems for P. brevitarsis.