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과제 수행 학습을 위한 학습 모형 분석 : 인터넷 영어 학습을 중심으로
강남희 The English Linguistic Science Association of Kore 2000 English Linguistic Science Vol.5 No.-
The purpose of the paper is to analyse internet sites of English learning, especially take-based loaming for EFLs and therefore to show a direction of developing textbooks for English teachers, concerning the seventh English education curriculum. The seventh English curriculum focuses on learners' self-dependence learning and learners-centered learning through various interactive activity in order to practice communicative competence. To establish these goals this paper shows and analyses several models in response to linguistic functions drawn from internet sites. The present author hopes that these analyses are helpful for English teachers as well as leasers and that it, furthermore, could be useful for designing textbooks regarding the seventh education curriculum.
남욱원,최철성,문신행,강희동 경북대학교 센서기술연구소 1990 센서技術學術大會論文集 Vol.1 No.1
1983 년경 국내에서도 과학탐사 로케트와 인공위성이 발사될 예정에 있으며 이에 따라 X-선 천체물리학을 위한 방사선 센서의 국내 개발이 시급히 요청되는 바이다. 따라서 현재 방사선계측에 많이 이용되고 있는 방사선 센서들 중 국내에서 개발되어온 MWPC위치검출기를 소개하고 인공위성 혹은 과학탐사로케트에 탑재되어 X-선 천체물리학연구에 이용될 경우 연구 개발되어 나가야 할 방향을 제시하고자 한다. Domestic sounding rocket and scientific satellite are scheduled to launch around 1993. The development of radiation sensor is required to observe X-rays coming from celestial bodies by the use of those space vehicleS. In this study we introduce the multi-wire position sensitive detector and the future works of onboard detector for X-ray astrophysics.
강원호,심희옥,남진경,김동출 忠南大學校 生命科學硏究院 醫藥品開發硏究所 2006 藥學論文集 Vol.21 No.-
A reversed phase HPLC method was developed and validated for the determination of nimodipine in human plasma. Nitrendipine was used as an internal standard. Calibration curves were linear in the concentration range of 5~300 ng/ml. The coefficient of variation of the intra- and inter-day precision was below 15%. The coefficient of variation of the accuracy was below 15% in the concentration range investigated. A bioavailability study was performed using the validated HPLC method. Eight healthy male volunteers were orally administered 30 mg of nimodipine. The pharmacokinetic parameters were calculated using WinNonlin. The mean values of AUC_(24hr) was 64.0±31.3 ng·hr/ml, C_(max) was 46.5±31.2 ng/ml, T_(max) was 0.54±0.17 hr and t_(1/2) was 3.03±2.26 hr. The pharmacokinetic parameters and the HPLC method can be used for the design of bioequivalence study of nimodipine.
강남미,유경희,김성재,조남옥,최희정 서울대학교 간호대학 간호과학연구소 1996 간호학 논문집 Vol.10 No.1
This study was conducted by critical review analyzing literatures of theories focused on changes of health behaviors. 5 theories-TRA, HBM, Self-Efficacy, Social Support, and Locus of Control-were selected among many theories of health behaviors. Theories were summarized, and models and concepts of theories were described. The results of this study were follows : 1. health behaviors could be classified into preventive behaviors and curative behaviors. 2. Most conceran of previous studies in this field was on health behavior execution itself or on its outcome. 3. the focus of previous studies was on initiation, maintenance, facilitation, and change of preventive and curative behaviors. 4. Factors affecting on health behaviors were demographic factors as exogenous variables and intrapsychic and extrapsychic factors as endogenous variables. 5. Previous studies tested predictability and explicability of these theories onhealth behaviors and identified factors affecting health behaviors most. 6. concepts of TRA, SELF-Efficacy, and Social support had higher explicability on health behaviors than concepts of HBM and Locus of control. From results of this study, we suggested the direction and considerations for futher nursing studies related with these theories. And we derived testable propositions from relationship between concepts and each others.
Phosphorylation modulators에 의한 항암제 다제내성 유전자의 발현 조절
김선희,곽남희,강치덕,정병선 부산대학교 유전공학연구소 1995 분자생물학 연구보 Vol.11 No.-
암을 치료함에 있어서 항암제에 대한 다제내성(MDR)의 획득이 중대한 장애로서 지적되고 있으며, MDR 현상은 MDRI 유전자의 과잉 발현에 의한 것으로 알려져 있다. MDRI promoter 활성이 mutated ras 또는 raf-1 발현에 의하여 증강되는 현상을 좀 더 명확히 하기 위하여 암 환자의 조직검체를 사용하여 RNA slot-blot 분석법으로 MDRI 유전자의 발현과 이들 암 유전자의 발현과의 관련성을 조사하였다. 3개의 대장암 검체에서 이들 암유전자의 높은 발현과 함께 MDRI gene도 높은 발현을 나타내었다. Raf-1에 의한 MDRI promoter의 최대 활성 증강을 나타내는 DNA 배열은 이 promoter 영역내의 HSE 영역과 일치하며, 또한 이 promoter에 작용하는 regulatory clement가 has70 promoter와 매우 유사하여 heat-induced(42℃) p432-CAT 발현에 있어 protein phosphatase inhibitor의 효과를 조사하였다. Okadaic acid나 calyculin은 농도 의존적으로 heat-induced p432-CAT의 발현을 증강시켰다. 또한 p56-CAT 발현이 forskolin에 의한 증강 또는 H-87에 의한 감소를 나타내어 이러한 현상은 MDRI promoter내의 CRE 유사 배열이 기능을 나타내는 것으로 사료되어 MDRI promoter가 has70 promoter와 유사하게 조절되며, Raf-1 발현에 의한 MDRI promoter의 활성화는 MDRI promoter내에 존재하는 HSE와 관련됨을 시사하였다. Multidrug resistance(MDR) poses a serious clinical problem in chemotherapy of cancer. MDR results from overexpression of the MDRI gene which encodes a drug-efflux pump called P-glycoprotein. To confirm our observation that the expression of mutated ras or raf-1 gene increased MDRI promoter activity, it was examined whether MDRI gene expression were correlated with the expression of these oncogenes in clinical tumor samples using RNA slot-blot analysis. These oncogenes were correlated with the expression of MDRI gene in 3 colon tumor samples. Since DNA sequence exhibiting maximum activation of MDRI promoter by Raf-1 is associated with heat shock element of MDRI promoter region, and regulatory element contained in MDRI promoter is very similar to that of hsp70 promoter. The effects of okadaic acid or calyculin on the heat-induced(42℃) expression of p432-CAT were determined. Okadaic acid or calyculin A potentiated the heat-induced expression of p432-CAT in dose-dependent manner. In addition, stimulation or inhibition of p56-CAT expression by forskolin or H-87, respectively suggests functional operation of CRE element in MDRI promoter. It is suggested that the regulation of MDRI promoter activity is very similar to that of hap70 promoter.
초등학교 1ㆍ2학년 영어재량활동을 위한 놀이와 게임 과제학습 개발
강남희 The English Linguistic Science Association of Kore 2001 English Linguistic Science Vol.7 No.-
The purpose of this study was to develop the play and game task models for the first and second elementary school students in special English activities. According to seventh curriculum, English as regular course is not provided for first and second elementary school students. It could be applied on the Special English Activities which aimed for self-directed study and whole-subjects learning. So play and game tasks oriented from activities are efficient for this goals. In order to the objective of the study, this study was composed as follows; First, identifing when an how English class for first and second grade can be organized. Second, identifying current curriculum the of which is seeking for eclectic and multi-dimensional syllabus and task-based learning(TBL), which may lead to be self-directed study for students. Third, Identifying whole subjects teaming, which may be adopted to design of syllabi. Forth, suggesting play and game task models for each grades. These models could be helpful for teachers, parents as well as students and be a solution for problems faced with current education.