THE IMPORTANT OF UNDERWATER HERITAGE FRAMEWORK TOWARDS NATIONAL MARITIME SOVEREIGNTY

Najmie M R,Madzli H,Yaakop Y A,Ahmad Z 국제이네비해양경제학회 2022 International Journal of e-Navigation and Maritime Vol.19 No.1

Underwater heritage is the term commonly used to mean material found underwater. Many states have heightened of underwater heritage remains unprotected. The UNESCO 2001 convention on the protection of the underwater cultural heritage is the foremost international legal reference for the protection or salvage of underwater heritage. To conduct a literature review for this thesis, five keywords were chosen such as UNESCO, under water cultural heritage, marine salvage and sovereignty, exploration, and investigation. The objective is; i) To ensure Malaysia underwater heritage is being well enforced by respective enforcement authorities.; ii) To create an awareness and protection to public and relevant parties.; iii) To identify the relevant implementation of legal enforcement from the respective Malaysia authority) To formulate Malaysia underwater cultural heritage strategic framework for enhancement sustainability development of underwater assets and wealth, and sovereignty. And for the problem statement, i) Lack of proactive measures from operational patrol of underwater cultural heritage for the enforcement from maritime authority,; ii) lack of public disclosure on the importance and existence of underwater heritage in Malaysia by stakeholders,; Iii) Lack of procedures and legal aspects for implementation of underwater cultural heritage in Malaysia water,;iv) None of national underwater cultural heritage strategic framework for sustainability of underwater assets and wealth in Malaysia. Specifically, the component of the underwater heritage is outlined for the protection and conservation of artifacts which have been partially or totally underwater. Qualitative method as main method and data collection from research book, journal article, publish and non-publish report. While expert interviewed via Webex within expert from academician and operational as supportive for this research. Text transcribed has been used for this research and coding system functioned for reference during discussion and findings. This thesis also uses theory of formulation and marine salvage as well as underwater cultural heritage law as a main reference. Finally, underwater cultural heritage strategic framework has been formulated regards to enhancement sustainability development of underwater assets and wealth, and sovereignty. thereby, it shown the Malaysian government commitment and concern to remain national maritime sovereignty.

Effects of QZ-16 on blood glucose and lipids in Streptozotocin induced diabetic rats

Najmi, Abul K.,Pillai, K.K.,Ahmad, Aftab,Aqil, M. Kyung Hee Oriental Medicine Research Center 2005 Oriental pharmacy and experimental medicine Vol.5 No.2

The present study was designed to investigate the hypoglycaemic and hypolipidaemic activities of Qurs-e-Ziabetus 16 (QZ-16) in Streptozotocin (STZ) induced diabetic rats. QZ-16, a polypharmaceutical herbomineral formulation developed on the principles of Unani medicine is used for non-insulin dependent diabetes mellitus (NIDDM). The elevated levels of fasting blood glucose, serum levels of cholesterol, triglycerides and urea observed in rats treated with STZ (55 mg/kg body wt.) were significantly reduced by the treatment of QZ-16 (240 mg/kg, p.o.) and gliclazide (30 mg/kg, p.o.). The reduced HDL cholesterol levels were also increased by the QZ-16 and gliclazide treatments in the STZ induced diabetic rats. These data show that QZ-16 has hypoglycaemic, hypolipidaemic properties in STZ induced diabetic rats.

Characterization of Biochar for Agricultural Use in North of Iran

Reza Najmi,Akbar Forghani,Atefeh Sabouri 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Attenuation of streptozotocin mediated oxidative stress, hyperglycemia and toxicity in rats by treatment with B-20 drpos - a homoeopathic preparation

Pillai, KK,Najmi, Abul K,Anwer, Tarique,Sultana, Yasmin,Sharma, Manju Kyung Hee Oriental Medicine Research Center 2007 Oriental pharmacy and experimental medicine Vol.7 No.1

The present study is aimed at finding the effect of B-20 drops, a homoeopathic formulation, in streptozotocin (STZ) induced diabetic rats. B-20 drops comprises of the constituents derived from plants and other natural sources, and are generally prescribed by the homoeopathic physician, in cases of hyperglycemia and diabetes. The elevated levels of fasting blood glucose and pancreatic lipid peroxides observed in rats treated with STZ were significantly reduced by the treatment of B-20 drops. The reduced liver glycogen contents were also brought back to near normal level by B-20 drops treatment in STZ diabetic rats. STZ induced histopathological changes in pancreas and liver was also partially reversed by B-20 drops. The findings indicate that B-20 drops help in improving the glycogen stores in the liver and prevents STZ induced damage through free radicals by decreasing the pancreatic lipid peroxides levels.

SOCIAL MEDIA ACTIVATION CAMPAIGNS: WHAT MAKES THEM ENGAGING AND HOW THEY INFLUENCE THE BRAND IMAGE

SeyedAlireza Mirbagheri,Manoochehr Najmi 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

Pharmacodynamic evaluation of hypoglycemic effect of Damtab in healthy adultmale volunteers

Pratap Kumar Sahu,AK Najmi,KK Pillai,Nilanjan Saha,Manju Sharma 경희대학교 융합한의과학연구소 2007 Oriental Pharmacy and Experimental Medicine Vol.7 No.2

The objectives of the study were (1) To evaluate the safety and tolerability of Damtab. (2) To characterize hypoglycemic effect of Damtab, if any. (3) To evaluate insulin sensitivity effect of Damtab, if any. Hypoglycemic effect of Damtab (700 mg and 1,400 mg) were examined. Gliclazide (80 mg) was used as an active control. Placebo was used as control. Breakfast was given, half an hour before dosing whereas lunch, snacks and dinner were given at 6, 10 and 14 h post dose. An oral glucose tolerance test was conducted to calculate the insulin sensitivity index from the values of glucose and insulin during oral glucose tolerance test. Both giclazide 80 mg and Damtab 1,400 mg significantly lowered plasma glucose level up to 6 h. Insulin sensitivity index of Damtab (1,400 mg) was found to be similar to that of placebo. A significant increase in insulin level at 1 h post dose of Damtab (1,400 mg) was observed. Damtab 700 mg shows placebo like effect whereas Damtab 1,400 mg possesses hypoglycemic effect.

Enhanced anti-inflammatory activity of curcumin, a naturally occurring pigment in turmeric via cyclodextrin complexation

Kohli, K,Ali, J,Najmi, AK,Anwer, MT,Ansari, MJ Kyung Hee Oriental Medicine Research Center 2007 Oriental pharmacy and experimental medicine Vol.7 No.2

Curcumin, a dietary pigment responsible for the yellow color of curry, has been used for the treatment of inflammatory diseases and exhibits a variety of pharmacological effects such as anti- inflammatory, anti-tumor, anti-oxidant, and anti-viral activity. In order to examine the potency of the curcumin in inflammation we used carrageenan induced rat hind paw odema model. As curcumin is practically water insoluble, it is hypothesized that pharmacological activity of curcumin could be improved by enhancing its water solubility. Water soluble complexes of curcumin with cyclodextrins were prepared and screened for greater solubility. Pure curcumin 100 mg/kg body weight along with curcumin complexes equivalent to 100 mg/kg body weight of pure curcumin were tested for the anti-inflammatory activity in Wister rats male rats using carrageenan induced hind paw edema model and compared with that of the reference compound diclofenac sodium at a dose level of 10 mg/kg body weight. Results were statistically analyzed using ANOVA. All the treatment groups showed statistically significant anti-inflammatory activity compared with that of vehicle control and positive control.

Intravaginal isonicotinic acid hydrazide (INH) versus misoprostol for cervical ripening prior to hysteroscopy

( Ladan Haghighi ),( Zahra Najmi ),( Samaneh Rokhgireh ),( Yousef Moradi ),( Candidate ) 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.4

Objective The aim of the present study was to compare the efficacy of vaginal isoniazid (isonicotinic acid hydrazide [INH]) and vaginal misoprostol in cervical ripening before hysteroscopic surgery. Methods This randomized controlled trial included patients scheduled for hysteroscopic surgery during April 2016 and June 2017. The inclusion criteria were as follows: postmenopausal women or those at premenopausal age who had not had a vaginal delivery and candidate for diagnostic or operative hysteroscopy with closed cervix before intervention. The INH group (intervention group) received 900 mg of vaginal isoniazid (three 300-mg pills) 6-8 hours before hysteroscopic surgery. The misoprostol group (control group) received 400 micrograms of vaginal misoprostol 6-8 hours before hysteroscopic surgery. Finally, the efficacy of the 2 agents was comparatively analyzed. Results Baseline characteristics were comparable between the groups. In 67 cases in the INH group (95%) and 45 in the misoprostol group (50%), hysteroscopic entry was successful without additional mechanical dilation, and this difference was statistically significant (P=0.001). The odds ratio (OR) obtained in this study was 0.57 for both INH and misoprostol groups (OR, 0.57; 95% confidence interval, 0.43-0.75). Further, 19 cases in the INH group vs. 45 cases in the misoprostol group did not respond to the intervention, indicating statistically significance (P=0.001). Conclusion Vaginal INH is more effective than misoprostol in cervical ripening before hysteroscopic surgery and can be a good alternative to misoprostol.

A novel approach towards controlled growth of metal-organic framework ZIF-8 thin film on steel with excellent corrosion protection

Navid Keshmiri,Parisa Najmi,Mohammad Ramezanzadeh,Bahram Ramezanzadeh 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.117 No.-

The control over the in-situ growth of metal-organic framework (MOF) thin films on a metal surface isstill challenging. As an interesting subdivision of MOFs, the zeolite imidazole framework (ZIF) has beenthe research hotspot in various research areas, from separation to sensing in the form of nanocrystals,thin films, and membranes. Continuous thin films of ZIF crystals need binding sites for desirable heterogeneousnucleation. This study proposed a novel and facile surface treatment at room temperature basedon zinc-phosphate conversion coating to provide nucleation sites for the intergrown ZIF-8 crystals onmild steel as a corrosion protective layer. The successful growth of ZIF-8 crystals on the modified carbonsteel was characterized using FT-IR, Raman, GIXRD, XPS, and FE-SEM tests. This thin layer led to a superprotective barrier film for up to 10 days in a harsh corrosive environment of salt spray. On the other hand,EIS reported almost 100 kO.cm2 total resistance after 72 h immersion in 3.5% wt. NaCl solution which is agreat achievement compared to conventional primer coatings. The total resistance of an epoxy coatingwith the proposed primer was improved by 135% when there was a deep mechanical scratch in the coating. The ZIF-8 thin film could significantly improve the epoxy coating’s anti-corrosion ability. The goodnews is that this concept is transferable to other ZIF-based MOFs.

Protective effect of silymarin in streptozotocin-induced diabetic dyslipidaemia in rats

Sharma, Manju,Pillai, K.K.,Anwer, Tarique,Najmi, Abul Kalam,Haque, Syed Ehtaishamul,Sultana, Yasmin Kyung Hee Oriental Medicine Research Center 2010 Oriental pharmacy and experimental medicine Vol.10 No.3

The present study investigated the effect of silymarin, a flavonoid, on streptozotocin (STZ) - induced diabetic dyslipidaemia in rats. Experimental diabetes was induced by a single intraperitoneal injection of STZ (60 mg/kg). Silymarin (25 mg/kg and 50 mg/kg) was orally administered to diabetic rats for a period of 15 days. Blood glucose levels, serum lipid profile and liver glycogen levels were estimated following the established procedures. Biochemical observations were supplemented with histological examination of liver sections. Oral administration of silymarin to diabetic rats significantly (P < 0.001) decreased the blood glucose levels ($259.99{\pm}23.64$ vs. $99.90{\pm}2.62$ [25 mg] & $89.17{\pm}3.32$ [50 mg]). The most interesting finding was the significant (p < 0.001) increase in HDL-cholesterol levels ($26.99{\pm}0.61$ vs. $40.55{\pm}0.52$ [25 mg] & $41.12{\pm}0.37$ [50 mg]) whereas, there was a significant decrease in serum total cholesterol (TCh), triglycerides (TG), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) cholesterol levels observed in silymarin treated diabetic rats. STZ treatment caused significant degeneration of liver parenchyma, which was normalized to near normal morphology by administration of silymarin. The findings indicate that silymarin effectively improved the overall lipid profile and restored the glycogen stores in the liver of STZ-induced diabetic rats, in a dose dependent manner. The results indicate existence of abnormalities in lipid metabolism in STZ-induced diabetic rats and suggest a protective effect of silymarin in this animal model.