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      • 설문지를 통한 양생기공학 강의평가 분석

        나삼식(Sam Sik Na),안훈모(Hun Mo Ahn) 대한의료기공학회 2017 醫療氣功 Vol.17 No.1

        Objective : This paper was written to develop clinically useful education system of 'Yang-Seng Gi-Gong' based on the principles of Korean medicine by analyzing the lecture evaluation through the questionnaire Methods : We surveyed 55 students who took 'Yang-Seng Gi-Gong' lectures at Wonkwang University School of Korean Medicine in 2016. Results : 1. The degree of reflection of the learning goal was 7.0 ± 2.1 and the overall interest was high in the regression analysis of the learning goal reflectivity. The satisfaction of the practical lecture was higher than the theoretical lecture. 2. In the evaluation of difficulty level, it was evaluated that the practical training was effective and the practice of standing position was the most difficult. 3. Due to the nature of the lectures, the difference between men and women was found in several items but it was not effective. 4. Generally, we appropriately assessed the preparation and progress of the class and practice. 67% of the respondents evaluated the current class as appropriate. 5. In the survey on participation in class, there was a high degree of participation in the practical lecture and a high correlation between overall participation and participation in the practical lecture. Conclusions: It is necessary to look for ways to concentrate with interest in the lecture, focusing on the practice, and to encourage the participation of women in the practice.

      • SCIESCOPUSKCI등재

        Reports : Mouse neutrophils express functional umami taste receptor T1R1/T1R3

        ( Na Hye Lee ),( Young Su Jung ),( Ha Young Lee ),( Nana Kang ),( Yoo Jung Park ),( Jae Sam Hwang ),( Young Yil Bahk ),( Jae Hyung Koo ),( Yoe Sik Bae ) 생화학분자생물학회(구 한국생화학분자생물학회) 2014 BMB Reports Vol.47 No.11

        Neutrophils play an important role in the initiation of innate immunity against infection and injury. Although many different types of G-protein coupled receptors are functionally expressed in neutrophils, no reports have demonstrated functional expression of umami taste receptor in these cells. We observed that mouse neutrophils express the umami taste receptor T1R1/T1R3 through RNA sequencing and quantitative RT-PCR analysis. Stimulation of mouse neutrophils with L-alanine or L-serine, which are ligands for the umami taste receptor, elicited not only ERK or p38 MAPK phosphorylation but also chemotactic migration. Moreover, addition of L-alanine or L-serine markedly reduced the production of several cytokines including TNF-α induced by lipopolysaccharide (LPS) through inhibition of NF-κB activity or STAT3 phosphorylation in neutrophils. Our findings demonstrate that neutrophils express the umami taste receptor, through which tastants stimulate neutrophils, resulting in chemotactic migration, and attenuation of LPS-induced inflammatory response. [BMB Reports 2014; 47(11): 649-654]

      • Molecular group system as one energy unit

        Na, Han Gil,Choi, Myung Sik,Bang, Jae Hoon,Oum, Wansik,Choi, Sun-Woo,Shim, Gyu Sam,Cho, Jae Hee,Kim, Hyoun Woo,Jin, Changhyun Elsevier 2019 CERAMICS INTERNATIONAL Vol.45 No.8

        <P><B>Abstract</B></P> <P>In view of the various qualifications required of materials nowadays, efforts to change the characteristics of inherent materials have continued. However, most material conversion techniques that have been used in the past, such as alloy design and doping effect, cannot overcome the limitation that properties are only added to the original characteristics of pristine materials. Therefore, herein, we introduced a new material design technique, a so-called “Molecular Group System”, which is completely different from existing methods. Since whole-set-systems are considered one-energetic-unit-system, either only the merits of the constituent elements can be emphasized or new materials completely different from the raw ones can be synthesized. In this study, block-stacking bottom-up approach was employed to form a one group system from SnO<SUB>2</SUB>, SnO<SUB>x</SUB>, Sn, and graphene powders, and a binder, using high-energy irradiation. Then, we discussed theoretical verifications such as SnO<SUB>2</SUB>-reduction and Sn-channeling.</P>

      • 의료기공(구 대한의료기공학회지)에 실린 임상논문의 경향 분석

        나삼식,정재훈,안훈모 대한의료기공학회 2020 醫療氣功 Vol.20 No.1

        Objective : The purpose of this study is to suggest the evidence of traditional Korean medicine by analyzing the clinical research trends of the Korean Academy of Medical Gi-Gong and to use it as reference data for future clinical studies. Methods : The clinical studies published in the Journal of the Korean Academy of Medical Gi-Gong from 2011 to 2019 were reviewed and the study design, yearly trends, patient's disease, therapeutic intervention, and outcome measure were analyzed. Results : Of the 24 clinical studies, there are 13 Case Reports, 9 Case Series Researches, and 2 Case-Control Studies. In terms of disease group, Musculoskeletal Diseases and female Diseases were the most common, followed by neurological Diseases, dermatological Diseases, and rare Diseases. In terms of treatment methods, acupuncture, herbal medicine, and Sugi therapy were mainly used. And cupping, thermotherapy, and Korean medical exercise therapy were used as a supplement. As an evaluation tool, clinical symptom change was the most common, followed by DITI, VAS, survey, and X-ray. In most reports, Korean medical treatment has been effective in treating diseases. Conclusions : More clinical studies including controlled clinical trials should be conducted to provide a basis for verifying the effectiveness of Korean medicine.

      • SCIESCOPUSKCI등재

        Nationwide Multicenter Study for Overlaps of Common Functional Gastrointestinal Disorders in Korean Patients With Constipation

        ( Kyung Sik Park ),( Sam Ryong Jee ),( Bong Eun Lee ),( Kyoung Sup Hong ),( Jeong Eun Shin ),( Soo-Young Na ),( Joong Goo Kwon ),( Suck Chei Choi ),( Yong Sung Kim ),( Hyun Seok Lee ),( Tae Hee Lee ) 대한소화기기능성질환·운동학회 2017 Journal of Neurogastroenterology and Motility (JNM Vol.23 No.4

        Background/Aims In spite of increased concerns about the overlaps among the various functional gastrointestinal disorders (FGIDs), studies for the overlap between constipation and other common FGIDs are rare. Therefore, we investigated the patterns of overlaps between constipation and other common FGIDs. Methods This study was designed as a prospective nationwide multi-center questionnaire study using Rome III questionnaires for functional dyspepsia (FD), irritable bowel syndrome (IBS), and functional constipation (FC), as well as various questionnaires about patients’ information, degree of symptoms, and quality of life. For the evaluation of gastroesophageal reflux disease (GERD), GERD-Q was used. Results From 19 centers, 759 patients with constipation were enrolled. The proportions of FC and IBS subtypes of constipation (IBS-C) were 59.4% and 40.6%, respectively. Among them, 492 (64.8%) showed no overlap. One hundred and thirty-six patients (17.9%) presented overlapping GERD, and 80 patients (10.5%) presented overlapping FD. Fifty one (6.7%) of patients were overlapped by both GERD and FD. Coincidental herniated nucleus pulposus (HNP) (P = 0.026) or pulmonary diseases (P = 0.034), reduced fiber intake (P = 0.013), and laxative use (P < 0.001) independently affected the rate of overlaps. These overlapping conditions negatively affected the constipation-associated quality of life, general quality of life, and degree of constipation. Conclusions The overlap of GERD or FD was common in patients with constipation. Coincidental HNP or pulmonary diseases, reduced fiber intake, and laxatives use were found to be independent associated factors for overlapping common FGIDs in Korean patients with constipation. (J Neurogastroenterol Motil 2017;23:569-577)

      • KCI등재

        Preoperative Extracorporeal Membrane Oxygenation for Severe Ischemic Mitral Regurgitation − 2 case reports −

        Tae Sik Kim,Chan-Young Na,Jong Hyun Baek,Jae-Hyun Kim,Sam-Sae Oh 대한흉부외과학회 2011 Journal of Chest Surgery (J Chest Surg) Vol.44 No.3

        Indication for extracorporeal membrane oxygenation (ECMO) has been extended as the experience of ECMO in various clinical settings accumulates and the outcome after ECMO installation improves. We report two cases of successful mitral valve surgery for severe ischemic mitral regurgitation in patients on ECMO support for cardiogenic shock which developed upon coronary angiography.

      • KCI등재

        Effects of LMX and Perceived Ethics with Leader on Job Burnout

        Young-Sam Oh,Beet-Na Choi,An-Sik Kim 한국유통과학회 2016 유통과학연구 Vol.14 No.8

        Purpose - This study has its purpose to identify the correlation between factors and moderating variables that can reduce job burnout by setting a positive relationship with a leader and ethicality of the leader as factors reducing job burnout and helping behavior as a moderating variable. Research design, data, and methodology - The research design would make theoretical perceived ethical leadership and LMX toward helping assistance, and job burnout using by structural equation method. Results - As a result, both positive behaviors and recognition on ethical leadership of a leader have been confirmed to influence on mitigation of job burnout. Especially, among the two factors, ethicality has shown to be more efficient to alleviate exhaust compared with positive behavior of a leader. Conclusions - Theoretical perceived ethical leadership and LMX toward a leader, helping assistance, and job burnout are statistically significant, however, the helping behavior of members is the factor increasing a job burnout. These results can be interpreted as the difficulties of relation setting with the members for the leader, and although loyalty and responsibility toward right leader may induce helping behavior, and positive behavior for organization can impact on the job burnout. It can be concluded that the ethicality of a leader is an essential factor for the development of organization.

      • 乳頭像 甲狀腺癌에서 VEGF, HIF-1α, E-cadherin, p53의 發現과 病期의 關聯性 硏究

        김종삼(Kim, Jong-Sam),나백주(Na, Bak-Ju),이무식(Lee, Moo-Sik),김철웅(Kim, Chul-Woung),정계림(Jeong, Gye-Rim) 한국산학기술학회 2009 한국산학기술학회 학술대회 Vol.- No.-

        본 연구에서는 HIF-1α의 과발현은 VEGF의 발현과 유의한 상관 관계가 있음을 보여 주었다. 그리고, HIF-1α의 과발현과 E-cadherin의 발현 사이에도 연관성은 있었지만 통계적인 유의성은 없었다. 종양의 병기와 VEGF, HIF-1α, E-cadherin, p53의 상관성을 살펴본 결과 E-cadherin에서만 유의성이 관찰되었다. 갑상샘 유두암종에서 HIF-1α의 발현이 종양의 증식과 관련된 단백, 특히 맥관형성과 관련된 단백인 VEGF의 발현, p53의 축적 및 E-cadherin의 발현소실과의 관계, 그리고 병리학적 표지자와의 관련성을 조사하고, 갑상샘 유두암종 환자의 수술후 예후와의 관계를 알고자 하였다.

      • 무심기공 도인법과 보법의 임상 적용 보고서

        나삼식,정재훈,필감매,Sam Sik Na,Jeong Jae hun,Gam Mai Pil 대한의료기공학회 2023 醫療氣功 Vol.22 No.1

        Objective : From March 2018 to July 2022, H Korean Medicine Hospital conducted a guidance on Gigong training using the Moosim Gigong Doinbeop and Moosim Gigong Walking. This report intends to report the results and share the specific methods of a guidance on Gigong training used in the process of implementation, thereby helping the research of a guidance on Gigong training later. Methods : The methods and results of the implementation of Moosim Gigong Doinbeop and Moosim Gigong Walking implemented by H Korean Medicine Hospital were reported. For the movements of Doinbeop, the posture and movements, the precautions to be taken when guiding, the alternative movements, and the meaning of the movements were summarized. For Moosim Gigong Walking, the method of progress, the method of motion, precautions to be taken, and replaceable movements were summarized. The method of implementing the guidance on Gigong training for severely ill and elderly patients was introduced. The application cases that were applied to some diseases and effective were recorded. Results : At H Korean Medicine Hospital, Moosim Gigong Doinbeop and Moosim Gigong Walking were conducted in the form of an open lecture, and 4,682 patients attended the Doinbeop class and 3,373 patients attended the Walking class. There is no restriction on the type of disease of the participating patients. The attending physician recommends and the patient wishes, the patient participates in the course. Conclusions : Curing technology is a long-standing treatment method of Korean Medicine, but it has not yet been activated in the modern Korean Medicine system. Research on the guidance on Gigong training can be conducted to establish itself as a new treatment method for Korean Medicine.

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