응급실에 내원한 환자에서 어지럼증의 원인과 임상양상의 분석

문원식,정경운,위준선,문정미,전병조,김용권,소정일,류진호,허탁,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: Recently, The number of patients who have been complaining of the vertigo or dizziness has been increasing due to rapid growth of elderly population and senile disease. The differentiation of dizzy patients is not familiar to most emergency physicians. This study was designed to differentiate true vertigo and to investigate the clinical difference among central vertigo, peripheral vertigo, and other causes of dizziness. Methods: The authors analyzed the cases of 237 dizzy patients who visited the emergency department of Chonnam University Hospital during the recent 2 years. For the base of dizziness, associated past illnesses, severity, nystagmus type, and the causes of central and peripheral vertigo. Results: Female patients were 142(59.9%) and male patients were 95(40.1%). The most common age group was the 6th decade. The origin of dizziness was classified as peripheral cause(25.3%), central cause(32.9%), and others(41.8%). As to nature of the dizziness, the rotatory sense was dominant in peripheral vertigo and the floating sense and blurred vision in central vertigo. Peripheral vertigo was triggered by position change of head and body, and central vertigo by the eye movement. Audiograms I showed that most patients with central vertigo had normal hearing, but 46.7% of thoswith peripheral vertigo had an abnormal hearing disturbance. Nystagmus was more prevalent in peripheral vertigo Conclusion: History taking and physical examination played an important role in the diagnosis of dizzy patients. An important part of the diagnosis of a dizzy patient could be to evaluate the peripheral origin, the central origin and others causes. Because central vertigo may be associated with a significant neurological pathology, spectral radiological studies, including MRI and CT, are mandatory to rule out a devastating brain lesion.

Effects of Stressed and Unstressed Reinforcements on Prestressed Concrete Members with Unbonded Tendons

Moon, Jeong-Ho,Shin, Kyung-Jae,Lim, Jae-Hyung,Lee, Sun-Hwa Korea Concrete Institute 2000 KCI concrete journal Vol.12 No.1

The research purpose of this paper is to investigate the influential Parameters on the unbonded tendon stress. The parameters were the reinforcing ratio, the prestressing ratio, and the loading type. To this end. first, the influence of parameters were examined with twenty eight test results obtained from references. Then, an experimental study was carried out with nine specimens. Test variables were the reinforcing ratio and the prestressing ratio. Specimens were divided equally into three groups and each group had a different level of the reinforcing ratio. Each specimen within a group has a different level of the prestressing ratio. The investigation with previous and current tests revealed the followings; (1) the length of crack distribution zone does not have a close relation with the length of plastic hinge. (2) the prestressing ratio does not affect both the length of crack distribution and the length of plastic hinge, (3) the tendon stress variation is in reverse relation with the ratios of mild steels and tendons, (4) the loading type nay not affect significantly the length of crack distribution zone, (5) AASHTO LRFD Code equation and Moon/Lim's design equation predicted the test results well with some safety margins.

An Experimental Study on Interrelation of Influential Parameters on Unbonded Tendon Stress

Moon, Jeong-Ho,Lim, Jae-Hyung Korea Concrete Institute 2006 International Journal of Concrete Structures and M Vol.18 No.e2

The purpose of this study is to investigate the relations between unbonded tendon stress and its influential parameters, i.e. bonded reinforcement ratio, span/depth ratio, and loading type. To this end, the influence of such parameters was examined with twenty eight test results of previous studies. Afterwards, an experimental study was carried out with twenty one test specimens. The investigation of previous and current experiments revealed the followings; (1) The bonded reinforcement ratio and prestressing ratio were proved to be important variables on the unbonded tendon stress. (2) The ratio of span to depth and the type of loading affected the unbonded tendon stress partially although their effects varied with bonded reinforcement ratio. (3) AASHTO LRFD Code and Moon/Lim's design equations predicted the experimental results well with the safety margin.

Antioxidant and cytoprotective effects of morin against hydrogen peroxide-induced oxidative stress are associated with the induction of Nrf-2-mediated HO-1 expression in V79-4 Chinese hamster lung fibroblasts

Lee, Moon Hee,Cha, Hee-Jae,Choi, Eun Ok,Han, Min Ho,Kim, Sung Ok,Kim, Gi-Young,Hong, Su Hyun,Park, Cheol,Moon, Sung-Kwon,Jeong, Soon-Jeong,Jeong, Moon-Jin,Kim, Wun-Jae,Choi, Yung Hyun Spandidos Publications 2017 International journal of molecular medicine Vol.39 No.3

<P>Natural phytochemicals of plant origin, including flavonoids, have been found to be potent antioxidants providing beneficial effects against oxidative stress-related diseases. The present study was carried out to investigate the antioxidant properties of morin, a flavonoid originally isolated from the flowering plants of the Moraceae family. Superoxide dismutase (SOD)-like activity and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(center dot+)) radical scavenging activity were determined. We also investigated the cytoprotective effects of morin against hydrogen peroxide (H2O2)-induced DNA damage and apoptosis in V79-4 Chinese hamster lung fibroblasts. Our results demonstrated that morin had strong scavenging effects against ABTS' radicals with enhanced SOD activity, which varied in a dose-dependent manner. Morin was found to reduce H2O2-induced intracellular reactive oxygen species generation and nuclear DNA damage, and it recovered cell viability damaged by H2O2 via inhibition of mitochondrial dysfunction-mediated apoptosis. Notably, the treatment of V79-4 cells with morin markedly enhanced the expression of heme oxygenase-1 (HO-1) but not quinone oxidoreductase-1, which was associated with the increased expression and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the downregulation of Kelch-like ECH-associated protein 1 expression. Based on our findings, we conclude that morin effectively ameliorated oxidative stress-induced DNA damage through intrinsic free radical scavenging activity and activation of the Nrf2/HO-1 pathway.</P>

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

연안산 패류를 이용한 조미소재의 가공 및 정미성분

문정호,강수태,김종태,오광수 경상대학교 해양산업연구소 2002 해양산업연구소보 Vol.15 No.-

고부가가치를 창출할 수 있는 새로운 식품가공용 풍미조미소계의 개발과 품질의 개선, 그리고 연안에서 생산되는 수산자원의 유효이용이라는 관점에서, 고부가 활용도가 거의 없는 바지락을 원료로 하여 고부가가치의 풍미계 조미소재 및 수프 소재로서 활용될 수 있는 유용 조미소재의 최적 가공조건을 구명하였고, 이의 정미성분을 분석하였다. 바지락 2단 효소분해 조미소재는 최적 가공공정은 다음과 같다. 시료 바지락을 chopper로써 세절한 다음 약 3배량의 물을 가하고, 98℃에서 5분간 자숙하여 자가소화효소를 불활성화시킨 후, 시료액의 pH를 8.0으로 조정하고 여기에 활성이 비교적 약한 내알칼리성 단백분해효소 가하여 교반하면서 55℃에서 4시간 동안 가수분해시킨다. 이어 자숙 처리하여 효소를 불활성화시킨 후 다시 pH를 6.0으로 조정하고, 여기에 exopeptidase 형의 중성 단백분해효소를 가한 다음 45℃에서 교반하면서 4시간 동안 가수분해시키고, 효소를 불활성화시킨 후 원심분리하여 상등액을 취함으로서 효소분해 조미소재를 얻을 수 있었다. 열수추출법, 자가소화법 및 2단효소분해법으로 바지락 조미소재를 조제하고, 각 조미소재의 특성을 서로 비교 검토한 결과, 바지락 열수 및 가압추출 조미소재에서는 대체로 감칠맛이 났으나 맛의 강도가 약하였고 패류취가 감지되었다. 바지락 2단 효소분해 조미소재는 감칠맛과 맛의 조화력이 월등히 강하였고, 특히 투명도 상승 등 조미소재의 물리적, 관능적 품질이 현저히 개선되었다. 바지락 열수 및 가압추출 조미소재, 2단효소분해 조미소재의 유리아미노산 총량은 각각 1,352.1 mg/100g, 1,174.1 mg/100g 및 2,122.4 mg/100g이었고, glutamic acid, glycine, alanine, tyrosine, phonylalanine, arginine 등이 주요 유리아미노산으로 추출방법에 따라 아미노산의 농도변화가 켰다. Betaine 함량은 116.O~845.0 mg/100g으로 열수추출이나 가압추출에 비해 효소분해 조미소재의 함량이 월등히 많았으며, 타 정미성분과도 함량을 비교해 볼 때 바지락 조미소재의 주된 정미성분일 것으로 추정되었다. 무기이온으로서 P, Na, K 및 Cl의 함량이 많았으며, 열수나 가압추출 조미소재에 비해 효소분해 조미소재 쪽이 함량이 훨씬 많았다. To develop natural flavoring substances, optimal two stage enzyme hydrolysis conditions and flavour compounds for short-neck clam enzyme hydrolysates were examined. The optimal enzyme hydrolysis conditions for two stage enzyme hydrolysate(TSEH) of short-neck clam were revealed in temperature at 55℃ for 4 hours digestion with alcalase at the 1st stage and 4 hours digestion at 45℃ with exopeptidase type neutrase at the 2nd stage. From the results in quality tests of hot-water extracts, steam extracts and 4 kinds of enzyme hydrolysates, TSEH processing method was superior to other methods on the aspects of yield, nitrogen contents, taste such as umami intensity and inhibition of off-flavor formation, and transparency of extract. And the flavor constituents and functionality of short-neck clam were also examined as affected by two stage enzyme hydrolysis. Total free amino acid contents in hot-water extract steam extract and TSEH of short-neck clam were 1,352.1 mg%, 1,174.1 mg% and 2,122.4 mg%, respectively. Major free amino acids in TSEH were glutamic acid, glycine, alanine, tyrosine, phenylalanine, arginine. As for nucleotides and other bases, betaine, TMAO and creatinine were principal components in TSEH. And the major inorganic ions in TSEH were Na, K, p and Cl

지자기 센서를 이용한 차량 속도 검지에 관한 연구

정대연,강문호 선문대학교 2001 공학계열 논총 Vol.4 No.-

This paper addresses a MR(Magneto-Resistive) sensor based vehicle speed detector which has been developed as an alternative to the conventional loop detector most available on the road. Consisting of two MR sensors and voltage amplifiers, microprocessor, RF module for wireless data transferring, the proposed detector can offer essential traffic data such as vehicle volume and speed. At first, basic speed detecting performance of the detector was verified with a simple car moving simulator in laboratory, and then real world field test was performed to show the practical usefulness as an alternative to the loop detector

남성유방에서 발생한 침윤성 선암종 1 예 : Report of a case

정유경,문현준,전호종 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Male breast cancer is rare compared to female breast cancer, about 1% or all breast cane or. The cause of male breast cancer is as poorly understood, but several etiologic factors have been suggested in the literature. Proposed risk factors include exogenous estrogen exposure, Klinefelter’s syndrome, gynecomastia and familial clustering. All of the microscopic types identified in the female breast have been encountered in males : the most common type is infiltrating duct carcinoma. Most often, it presents as a painless lump and subareolar in origin. Comparison with female breast cancer reveals no difference with regard to incidence of positive axillary lymph nodes. However there is a sightly lower survival rate for men. The stage of disease is the only parameter that significantly affects outcome. We report a case of breast cancer arising right subareolar area in a 57 year-old male. There were no familial history, Klinefelter's syndrome and microscopic evidence of gynecomastia. Histologically, this tumor was infiltrating duct carcinoma disposed in nests sometimes glands .

외상 후 뇌 지방색전증 1예

문정미,소정일,김용권,류진호,허탁,서정진,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Post-traumatic fat embolism was first reported by Zenker in 1862, Von Bergmann reported the first clinical diagnosis of the fat embolism syndrome in 1873. Fat embolism has been associated with traumatic or non-traumatic disorders. Fat embolization after long bone trauma is probably common as a subclinical event. The diagnosis of fat embolism syndrome is based on the patient's history, is supported by clinical signs of pulmonary, cerebral, and cutaneous dysfunction, and is confirmed by the demonstration of arterial hypoxemia in the abscence of other disorders. Two different mechanisms cause fat to embolize: direct entry of deposit fat into the blood stream and agglutination of endogenous or exogenous plasma fat. MRI can detect a cerebral fat embolism with a higher sensitivity than cerebral CT. We report a case of post-traumatic cerebral fat embolism without pulmonary involvement, and we present a review of the literature. A 16-year girl had a traffic accident and pelvic bone fracture. Forty eight hours later severe trauma become stuporous without a focal neurological deficit. The patient received supportive therapy, and her condition improved throughout her hospital course. She was discharged with good condition after a 30-day hospital stay.

38세 남자환자에서 발생한 만발성 림프부종 1예

정호중,김기찬,엄문섭 고신대학교의과대학 2006 고신대학교 의과대학 학술지 Vol.21 No.2

Primary lymphedema tarda is considered to be a congenital disease with delayed manifestations. The cause is unknown; an autoimmune destruction of lymphatic channels can be hypothesized. We report a case of isolated lymphedema of the left lower extremity in a 38-year-old male. The diagnosis of lymphedema was confirmed by lymphoscintigraphy and appropriate diagnostic studies were done to rule out other known causes of limb edema. We report a rare case of primary lymphedema tarda of the left lower extremity.