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Mohseny, Maryam,Amanpour, Farzaneh,Mosavi-Jarrahi, Alireza,Jafari, Hossein,Moradi-Joo, Mohammad,Monfared, Esmat Davoudi Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup3
Breast cancer is one of the most common causes of cancer mortality in Iran. Social determinants of health are among the key factors affecting the pathogenesis of diseases. This cross-sectional study aimed to determine the social determinants of breast cancer survival time with parametric and semi-parametric regression models. It was conducted on male and female patients diagnosed with breast cancer presenting to the Cancer Research Center of Shohada-E-Tajrish Hospital from 2006 to 2010. The Cox proportional hazard model and parametric models including the Weibull, log normal and log-logistic models were applied to determine the social determinants of survival time of breast cancer patients. The Akaike information criterion (AIC) was used to assess the best fit. Statistical analysis was performed with STATA (version 11) software. This study was performed on 797 breast cancer patients, aged 25-93 years with a mean age of 54.7 (${\pm}11.9$) years. In both semi-parametric and parametric models, the three-year survival was related to level of education and municipal district of residence (P<0.05). The AIC suggested that log normal distribution was the best fit for the three-year survival time of breast cancer patients. Social determinants of health such as level of education and municipal district of residence affect the survival of breast cancer cases. Future studies must focus on the effect of childhood social class on the survival times of cancers, which have hitherto only been paid limited attention.
Genomic Profiling of Chronic Myelogenous Leukemia: Basic and Clinical Approach
Aliasghar Keramatinia,Alireza Ahadi,Mohammad Esmaeil Akbari,Maryam Mohseny,Alireza Mosavi Jarahi,Narjes Mehrvar,Neda Mansouri,S.A. Mortazavi Tabatabaei,Abolfazl Movafagh 대한암예방학회 2017 Journal of cancer prevention Vol.22 No.2
Chronic myeloid leukemia (CML) is a hematological stem cell cancer driven by BCR-ABL1 fusion protein. We review the previous and recent evidence on the significance of CML in diagnostic and clinic management. The technical monitoring of BCR-ABL1 with quantitative real time-PCR has been used in assessing patient outcome. The cytogenetic mark of CML is Philadelphia chromosome, that is formed by reciprocal chromosomal translocations between human chromosome 9 and 22, t(9:22) (q34:q11). It makes a BCR-ABL1 fusion protein with an anomaly tyrosine kinase activity that promotes the characteristic proliferation of progenitor cells in CML and acute lymphoblastic lymphoma. The targeting of BCR-ABL1 fusion kinase is the first novel paradigm of molecularly targeted curing.
Contralateral Superior Cerebellar Artery Syndrome : A Consequence of Brain Herniation
Mohseni, Meysam,Habibi, Zohreh,Nejat, Farideh The Korean Neurosurgical Society 2017 Journal of Korean neurosurgical society Vol.60 No.3
Vascular compromise is a well-known consequence of brain herniation syndromes. Transtentorial brain herniation most often involves posterior cerebral arteries. However, isolated involvement of contralateral superior cerebellar artery (SCA) during unilateral impending brain herniation is reported only once and we present another case of this exceedingly rare entity. A 24-year-old man was referred to us with impending herniation due to a multiloculated hydrocephalus, and during the course of illness, he developed an isolated SCA ischemia in the opposite side of the most dilated entrapped horn. In the current article we discuss the probable pathophysiologic mechanisms of this phenomenon, as well as recommending more inclusive brain studies in cases suspected of Kernohan-Woltman notch phenomenon in unilateral brain herniation. The rationale for this commentary is that contralateral SCA transient ischemia or infarct might be the underdiagnosed underlying pathomechanism of ipsilateral hemiparesis occurring in many cases of this somehow vague phenomenon.
Anoushiravan Mohseni Bandpei,Seyed Mohsen Mohseni,Amir Sheikhmohammadi,Mahdieh Sardar,Maryam Sarkhosh,Mohammad Almasian,Moayad Avazpour,Zahra Mosallanejad,Zahra Atafar,Shahram Nazari,SoheilaRezaei 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.2
Arsenic is a critical contaminant for aqueous environments as it poses harmful health risks. To meet the stringent regulations regarding the presence of arsenic in aqueous solutions, the feasibility of montmorillonite clay modified with hexadecyltrimethyl ammonium chloride as the adsorbent was tested for the removal of arsenic ions from aqueous solutions. A scanning electron microscopy (SEM) study confirmed that the organically modified nanoclay (ONC) adsorbent had a porous structure with a vast adsorbent surface. The x-ray fluorescence (XRF) analysis proved the presence of carbon in the structure of the modified nanoclay that can be evidence for the creation of ONC. The x-ray diffraction (XRD) analysis results confirm the existence of four main groups of minerals, carbonate (Calcite), clay (Askmtyt and Kandyt), silicate (Quartz), and phyllosilicate (Kaolinite), in the ONC structure.The influence of various parameters such as solution pH, adsorbent dosage, initial arsenite concentration, and contact time on arsenic adsorption onto ONC was investigated. A 25 full factorial central composite experimental design was applied. A central composite design under response surface methodology (RSM) was employed to investigate the effects of independent variables on arsenite removal and to determine the optimum condition. The experimental values were in a good fit with the ones predicted by the model. The optimal operating points (adsorbent dosage: 3.7 g L−1, surfactant dosage: 3 g L−1 and the contact time: 37.2min) giving maximum arsenite removal (95.95%) were found using Solver “Add-ins” in Microsoft Excel 2010.
Effect of Intermediate Diaphragm on Lateral Load Distribution Factor of Multicell Box-girder Bridges
Iman Mohseni,Abdul Khalim Abdul Rashid,Junsuk Kang 대한토목학회 2014 KSCE JOURNAL OF CIVIL ENGINEERING Vol.18 No.7
The current American bridge design codes state that intermediate diaphragms should be used to preserve section geometry against accidental overturning of girders and during construction of a bridge. There is inconsistency in practice for the design of intermediate diaphragms, such that most specifications either ignore or underestimate the contribution of these members to the lateral distribution of live load. Current studies indicate that neglecting the effect of intermediate diaphragms might lead to highly conservative values for bending moment distribution factors and result in non-economic designs for skew bridges. This paper reports on a parametric study performed on 160 prototypes of straight and skew concrete multicell box-girder bridges. The obtained results were used to develop practical expressions to account for the diaphragm effects on American Association of State Highway and Transportation Officialsformulas for live load distribution factors. It was observed that decks with internal transverse diaphragms perpendicular to the longitudinal webs are the best arrangement for load distribution in skew bridges. Thus, a sufficient number of diaphragms should be provided between span lengths and over the supports of bridge decks.