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Hu Hongyan,Wang Xiaowei,Wu Zhijun,Chen Mo,Chai Tuanyao,Wang Hong 한국식물학회 2022 Journal of Plant Biology Vol.65 No.6
Plants have evolved complex signaling networks that enable them to adapt to adverse environmental conditions. The dehydration-responsive element-binding (DREB) transcription factors are important for plant responses to abiotic stresses. In this study, a new member of the AP2/ERF transcription factor gene family, PcDREB2A, was cloned and characterized from Polygonum cuspidatum, a traditional Chinese medicinal herb. PcDREB2A, which includes a typical AP2 domain, was clustered in the A-2 subgroup of the DREB subfamily. At the seedling stage, PcDREB2A expression was induced by cold, salt, and drought stresses. A yeast one-hybrid assay and an analysis of transiently transformed tobacco revealed that PcDREB2A can specifically bind to the DRE motif and transactivate reporter gene expression. Following 200 and 250 mM mannitol treatments, the PcDREB2A-overexpressing Arabidopsis thaliana lines had longer roots and a significantly higher fresh weight than the wild-type plants. Furthermore, under drought stress conditions, the PcDREB2A-overexpressing A. thaliana plants accumulated less malondialdehyde than the control plants. These results indicate that PcDREB2A encodes a novel DREB transcription factor in P. cuspidatum. Furthermore, the data generated in this study may be useful for researchers and breeders interested in genetically engineering plants to increase drought tolerance without inhibiting growth.
허영문,양훈모,심동원 순천향대학교 1992 논문집 Vol.14 No.4
To investigate the effect of extreme high temperature on the cardiopulmonary function, we measured the heart rate, blood pressure, lung volumes, and breath-holding time before and during exposure to 70℃ environment in male adults. 1) The heart rate demonstrated exquisite sensitivity to extreme high temperature; exposure to heat increased the heart rate from 75 bpm to 124 bpm(65% increase). 2) There was a tendency for both systolic and diastolic pressure to decrease, which was not statistically significant. 3) While the exposure increased the respiratory rate from 19/min to 28/min (47% increase), it decreased the tidal volume from 566ml to 314ml. 4) The vital capacity decreased from control of 4.31 L to 3.26 L during exposure. The exposure also decreased the maximum breathing capacity (before exposure, 99 L; during exposure, 56 L0. 5) The breath-holding time decreased from 48 sec to 38 sec during exposure.
Shellix : An Efficient Approach for Shellcode Detection
Mo Chen,Changzhen Hu,Donghai Tian,Xin Wang,Yuan Liu,Ning Li 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.6
Code injection attacks are widely used by attackers to compromise computer systems. Attackers could obtain the control of a victim's computer system by injecting shellcode to the vulnerable program. The existing solutions to detect shellcode can be grouped into two categories: static analysis and dynamic analysis. Static analysis can detect shellcode efficiently, but cannot handle the shellcode that employs obfuscation techniques. Dynamic analysis is able to detect the obfuscated shellcode, however it is still limited to detect the recent virtualization-aware shellcode. In this paper, we present a novel shellcode detection approach without using any virtualization technology. We implement our approach based on the commodity OS kernel which is compatible to the existing system. Our approach is able to detect the shellcode that could be aware of the virtualization environment and reduces the probability of exposing detection environment. Our experimental evaluations show that our system can effectively detect a large set of shellcode instances with good performance.
Haokun Hu,Lipo Mo,Fei Long 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.4
The mean-square consensus of the discrete-time heterogeneous multi-agent systems (HMASs) with convex position constraints, nonconvex velocity constraints and communication noises is reported in this paper, where the dynamics of HMASs are composed of first-order or second-order difference equations, and the noises are assumed to be martingale difference sequences. Firstly, a new algorithm is designed based on the information from neighbor agents with noises, and the original system is changed into an equivalent one by introducing a coordinate transformation. Secondly, when the communication graph is joint strongly connected, it is proved that mean-square consensus can be achieved by the properties of stochastic matrix, projection operator and martingale, and the position and velocity states of agents stay at the corresponding constraint sets. Specially, the situations of a network containing only first-order agents or second-order agents are considered, respectively. Finally, the correctness of the theoretical results is verified by numerical simulations.
Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition
Huang, Hu,Lee, Seung-Hwan,Sousa-Lima, Inê,s,Kim, Sang Soo,Hwang, Won Min,Dagon, Yossi,Yang, Won-Mo,Cho, Sungman,Kang, Min-Cheol,Seo, Ji A.,Shibata, Munehiko,Cho, Hyunsoo,Belew, Getachew Debas,Bhi American Society for Clinical Investigation 2018 The Journal of clinical investigation Vol.128 No.12
A SDR Prototype for Backscatter Sensor Networks
Jinrong Mo,Shengbo Hu,Feng Lv,Yanfeng Shi,Tingting Yan 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.10
Low cost and low power is one of the important reasons in the wide application of backscatter sensor networks. Based on LabVIEW and USRP platforms, this paper presents and implements a simple and configurable SDR prototype for backscatter sensor networks. The SDR prototype can apply to the multi-sensor environment with low power. The prototype consists of configurable backscatter transceiver with homodyne receiver and sensor nodes. It can reduce the power consumption of system efficiently through harvesting wireless RF energy and waking sensor nodes. The frequency division multiple access method with configurable sub-carrier is proposed, and the constraint conditions of sensing data pulse period for avoiding collision among sensors are presented and proved in this paper. The performance of the prototype is analyzed, and the closed-form solution of the probability of outage under the log-normal channel is also given and proved. Finally, the experiment and simulation show the SDR prototype is effective and feasible. The EVM value is less than 2.8%, and the probability of outage error between numerical analysis and Monte Carlo simulation is less than 1.86%.
KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1
( Jun Jian Hu ),( Wu Zhou Yuan ),( Ming Tang ),( Yue Qun Wang ),( Xiong Wei Fan ),( Xiao Yang Mo ),( Yong Qing Li ),( Zao Chu Ying ),( Yong Qi Wan ),( Karen Ocorr ),( Rolf Bodmer ),( Yun Deng ),( Xiu 생화학분자생물학회 2010 BMB Reports Vol.43 No.1
Kun Yang,Mo-Xi Chen,최윤영,Zong-Guang Zhou,형우진,노성훈,Jian-Kun Hu 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.2
Purpose: This study aimed to investigate the effectiveness of postoperative chemotherapy in pT1bN0 and pT2N0 gastric cancerpatients with high risk factors. Materials and Methods: Clinicopathological data of gastric cancer patients, who had undergone gastrectomy in high volumecenters in Korea and China and were finally diagnosed with pT1bN0 and pT2N0 between 2006 and 2010, were analyzed retrospectively. Survival analyses stratified by risk factors and multivariable analyses were performed. Results: A total of 1509 patients were enrolled, with 41 (2.7%) patients receiving adjuvant chemotherapy after gastrectomy and1468 (97.3%) patients undergoing surgery alone. The adjuvant chemotherapy group showed higher percentages of tumor withmaximal diameter >3 cm (51.2% vs. 25.8%), poor differentiation (68.3% vs. 49.8%), and less harvested lymph nodes (17.1% vs. 5.2%) compared to the surgery alone group. The overall survival rates were 95.1% in the adjuvant chemotherapy group and 93.3%in the surgery alone group, without significant difference. In multivariable analysis, age was found to be an independent prognosticfactor. However, there were no difference in the overall survival between patients with risk factors and those without risk factors,even in terms of age. Meanwhile, patients with more than two risk factors who received chemotherapy showed better survivaltrend, especially for pT2N0 patients, compared to the surgery alone group, although no significant differences were observed. Conclusion: In pT1bN0 and pT2N0 patients, age was found to be an independent prognostic factor. However, adjuvant chemotherapyseemed to be unnecessary, while postoperative chemotherapy might offer survival benefits to pT2N0 patients with morethan two risk factors.