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( Min Kyun Na ),( Choong Hyun Kim ),( Jae Min Kim ),( Jin Whan Cheong ),( Je Il Ryu ),( Hyun Woo Kim ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2016 Brain Tumor Research and Treatment Vol.4 No.2
Esophageal carcinoma rarely metastasizes to the brain. Although some studies have mentioned esoph-ageal cancer with solitary brain metastasis or with meningocerebral metastasis or with skull metastasis, multiple meningocerebral metastasis and extensive skull metastasis from squamous cell carcinoma of esophagus has not been reported in the literature. We encountered a case of an extensive osteolytic change of the skull and multiple meningocerebral metastases from esophageal carcinoma.
Medicinal Chemistry : Quantitative Determination of Diterpenoids from the Roots of Aralia cordata
( Min Kyun Na ),( Ki Hwan Bae ),( Young Ho Kim ),( Jae Sue Choi ),( Byung Sun Min ),( Ik Soo Lee ),( Jong Keun Son ),( Tran Manh Hung ),( Mi Hee Woo ),( Mi Kyoung Lee ) 영남대학교 약품개발연구소 2009 영남대학교 약품개발연구소 연구업적집 Vol.19 No.-
( Min Kyun Na ),( Yong Tae Jeong ),( Xian Li ),( Fansi Jin ),( Seung Lark Hwang ),( Geum Jin Kim ),( Ju Hye Yang ),( Young Chae Chang ),( Dong Soo Kim ),( Cheorl Ho Kim ),( Hyeun Wook Chang ) 영남대학교 약품개발연구소 2015 영남대학교 약품개발연구소 연구업적집 Vol.25 No.-
The effect of butanol extracts of the skin of Anguilla japonica (BESA) on endoplasmic reticulum (ER) stress-induced insulin resistance in L6 myotubes was investigated. Western blotting revealed that BESA increased phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase, and stimulated glucose uptake in L6 myotubes. Stimulation of AMPK and glucose uptake by BESA were significantly (p<0.05) reduced by siRNA LKB1 or siRNA AMPK, compared with controls, suggesting that enhanced glucose uptake by BESA was predominantly accomplished via an LKB1-mediated AMPK activation pathway. In addition, BESA effectively reduced phosphorylation of ER stress markers, RNA-activated protein kinaselike ER resident kinase, JNK, and significantly (p<0.01) increased glucose uptake via AMPK activation in tunicamycin-treated L6 myotubes, compared with controls. Improvement of insulin sensitivity under ER stress conditions by BESA is predominantly accomplished via an LKB1- AMPK-dependent pathway.