Identification and Antibiotic Susceptibility of the Bacteria from Non-odontogenic Infectious Lesions

Yong Min Kim,Jae-Jin Kim,Mija Kim,Soon-Nang Park,Hwa-Sook Kim,Joong-Ki Kook,Hak Kyun Kim KOREAN ACADAMY OF ORAL BIOLOGY 2014 International Journal of Oral Biology Vol.39 No.2

The purpose of this study was to isolate and identifybacteria from the 4 patients with non-odontogenic infectiouslesions (mucormycosis, chronic inflammation from woundinfection, and two actinomycosis) and determine theirantimicrobial susceptibility against eight antibiotics. Bacterial culture was performed under three cultureconditions (anaerobic, CO2, and aerobic incubator). Thebacterial strains were identified by 16S rRNA gene (16SrDNA) sequence comparison analysis method. Forinvestigating the antimicrobial susceptibility of the bacteriaagainst eight antibiotics, penicillin G, amoxicillin,tetracycline, cefuroxime, erythromycin, clindamycin, vancomycin, and Augmentin® (amoxicillin + clavulanicacid), minimum inhibitory concentration (MIC)measurement was performed using broth microdilutionassay. Nosocomial pathogens such as Enterococcus faecalis,Klebsiella pneumoniae, Bacillus subtilis, and Neisseriaflavescens were isolated from mucormycosis. Veillonellaparvula, Enterobacter hormaechei, and Acinetobactercalcoaceticus were isolated from chronic inflammatorylesion. Actinomyces massiliensis was isolated fromactinomycosis in parotid gland. Capnocytophaga ochraceawas isolated from actinomycosis in buccal region inanaerobic condition. There was no susceptible antibiotic toall bacteria in mucormycosis. Tetracycline was susceptibleto all bacteria in chronic inflammation. C. ochracea wasresistant to vancomycin and penicillin G; and otherantibiotics showed susceptibility to all bacteria inactinomycosis. The results indicated that the combinedtreatment of two or more antibiotics is better than singleantibiotic treatment in mucormycosis, and penicillin is thefirst recommended antibiotic to treat actinomycosis

The Types of Korean As-Parenthetical Constructions

Kim, Mija Korean Society for Language and Information 2015 언어와 정보 Vol.19 No.1

This paper is primarily intended to provide a new insight on which the structural properties of As-Parenthetical constructions shown by Potts (2002) might be regarded as cross-linguistically common one. As a first attempt, it introduces the characteristics of Korean As-Parenthetical by carefully investigating them through the data, focusing on the similarities or differences between two languages with a constructional theoretical perspective. The paper here provides three properties of Korean as-clauses in the morphological and syntactic aspects. First, the morpheme 'as' in English as-clause would be realized as three different morphemes as a bound one. Korean as-clauses can be introduced by three different morphemes, '-tusi, -chelem, -taylo' and unlike that in English as-clauses, they behave as bound morphemes which do not stand alone. Even though they are attached into different morpho-syntactic stems, they do not make any meaning change only under this clause. Secondly, two syntactic types of as-clauses can also be found in Korean, similarly to those of English: CP-As type and Predicate-As type, depending on which types of gap they involve in. English has one more subtype of Predicate-As type (called inverted Predicate-As clause), while Korean does not show this subtype. Thirdly, the various mismatches attributed by the gap and the antecedent come from the constructional restrictions of as-clauses in Korean. In addition, the paper attempts to display various ambiguities from the as-clauses through disjoint references or negative sentences in As-Parenthetical constructions.

Genitive Alternations of the One’s Own Possessive Construction

( Mija Kim ) 한국언어정보학회 2021 언어와 정보 Vol.25 No.1

Possessive constructions have received considerable attention from researchers who have concentrated exclusively on genitive alternations. This paper aims to introduce a new type of possessive construction, the one’s own construction, focusing, inter alia, on quantitative and statistical analyses of its genitive alternation, as there is still no research in this area. This new type of possessive construction also shows a genitive alternation of the s-genitive own and the of-genitive own, similar to that of regular possessive constructions. The study intends to identify the crucial factors that determine the use of these two alternative genitive forms. Following the conventional wisdom, the study adopts as variables four semantic factors-animacy, abstractness, alienability, and part-whole, and distinguishes the differences among the types. The results show that (1) the more animate the referent of a possessum is, the more likely it is to occur in the of-genitive own construction; (2) the abstract possessum appears more frequently as an s-genitive own construction; (3) the more inalienable the relationship is, the more likely it is to be realized as an of-genitive own construction; and (4) the s-genitive own shows a much stronger part-whole relationship than the of-genitive own construction. These findings prove statistically significant. Focusing on these results, this study concludes that the syntactic distribution of the of-genitive own type is determined by the semantic or pragmatic features, ultimately identifying a distinctive grammatical feature: specifically, the of-genitive own type is a grammatical construction of its own to denote the stronger degree of close possession established between animate entities.

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152

Kim, Tae-Sung,Park, Jung-Eun,Shukla, Anil,Choi, Sunho,Murugan, Ravichandran N.,Lee, Jin H.,Ahn, Mija,Rhee, Kunsoo,Bang, Jeong K.,Kim, Bo Y.,Loncarek, Jadranka,Erikson, Raymond L.,Lee, Kyung S. National Academy of Sciences 2013 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.110 No.50

<P>Centrosomes play an important role in various cellular processes, including spindle formation and chromosome segregation. They are composed of two orthogonally arranged centrioles, whose duplication occurs only once per cell cycle. Accurate control of centriole numbers is essential for the maintenance of genomic integrity. Although it is well appreciated that polo-like kinase 4 (Plk4) plays a central role in centriole biogenesis, how it is recruited to centrosomes and whether this step is necessary for centriole biogenesis remain largely elusive. Here we showed that Plk4 localizes to distinct subcentrosomal regions in a temporally and spatially regulated manner, and that Cep192 and Cep152 serve as two distinct scaffolds that recruit Plk4 to centrosomes in a hierarchical order. Interestingly, Cep192 and Cep152 competitively interacted with the cryptic polo box of Plk4 through their homologous N-terminal sequences containing acidic-alpha-helix and N/Q-rich motifs. Consistent with these observations, the expression of either one of these N-terminal fragments was sufficient to delocalize Plk4 from centrosomes. Furthermore, loss of the Cep192- or Cep152-dependent interaction with Plk4 resulted in impaired centriole duplication that led to delayed cell proliferation. Thus, the spatiotemporal regulation of Plk4 localization by two hierarchical scaffolds, Cep192 and Cep152, is critical for centriole biogenesis.</P>

Evaluation of accuracy of 3D reconstruction images using multi-detector CT and cone-beam CT

Mija Kim,Kyung-Hoe Huh,Won-Jin Yi,Min-Suk Heo,Sam-Sun Lee,Soon-Chul Choi 대한구강악안면방사선학회 2012 Imaging Science in Dentistry Vol.42 No.1

Purpose : This study was performed to determine the accuracy of linear measurements on three-dimensional (3D) images using multi-detector computed tomography (MDCT) and cone-beam computed tomography (CBCT). Materials and Methods : MDCT and CBCT were performed using 24 dry skulls. Twenty-one measurements were taken on the dry skulls using digital caliper. Both types of CT data were imported into OnDemand software and identification of landmarks on the 3D surface rendering images and calculation of linear measurements were performed. Reproducibility of the measurements was assessed using repeated measures ANOVA and ICC, and the measurements were statistically compared using a Student t-test. Results : All assessments under the direct measurement and image-based measurements on the 3D CT surface rendering images using MDCT and CBCT showed no statistically difference under the ICC examination. The measurements showed no differences between the direct measurements of dry skull and the image-based measurements on the 3D CT surface rendering images (P>.05). Conclusion : Three-dimensional reconstructed surface rendering images using MDCT and CBCT would be appropriate for 3D measurements.

Degree Complement Clause Constructions in English

( Mija Kim ) 한국언어정보학회 2016 언어와 정보 Vol.20 No.3

The degree complement clause constructions, which the degree words so, too, enough form by obligatorily combining with that-clause denoting much more specific degree scale, exhibit complex syntactic structures, in that they are not adjacent each other although the degree words and that-clause are strongly associated with the close relationship of a head and complement. This paper is primarily intended to develop the syntactic structures for the diverse types of result clauses. We got the results that the result clauses can be classified into the five different types by each degree word in terms of their distribution and function. We divided them into canonical and noncanonical result clauses. The canonical type shows the characteristics that the diverse categories such as AP, AdvP, NP, VP and PP can be occupied between a degree word and that-clause and they function as a head in their phrases. This canonical type includes two subtypes like pre-degree type and post-degree type. The noncanonical clauses were subdivided into prenominal type, postnominal type, and degree-of type. The result of this paper showed that the noncanonical result clauses can occur just around an NP position. Focusing on these distributional types, this paper has set up their syntactic structures by types. (Kyung Hee University)

The Types of Korean As-Parenthetical Constructions

( Mija Kim ) 한국언어정보학회 2015 언어와 정보 Vol.19 No.1

This paper is primarily intended to provide a new insight on which the structural properties of As-Parenthetical constructions shown by Potts (2002) might be regarded as crosslinguistically common one. As a first attempt, it introduces the characteristics of Korean As-Parenthetical by carefully investigating them through the data, focusing on the similarities or differences between two languages with a constructional theoretical perspective. The paper here provides three properties of Korean as-clauses in the morphological and syntactic aspects. First, the morpheme ‘as’ in English as-clause would be realized as three different morphemes as a bound one. Korean as-clauses can be introduced by three different morphemes, ‘-tusi, -chelem, -taylo’ and unlike that in English as-clauses, they behave as bound morphemes which do not stand alone. Even though they are attached into different morpho-syntactic stems, they do not make any meaning change only under this clause. Secondly, two syntactic types of as-clauses can also be found in Korean, similarly to those of English: CP-As type and Predicate-As type, depending on which types of gap they involve in. English has one more subtype of Predicate-As type (called inverted Predicate-As clause), while Korean does not show this subtype. Thirdly, the various mismatches attributed by the gap and the antecedent come from the constructional restrictions of as-clauses in Korean. In addition, the paper attempts to display various ambiguities from the as-clauses through disjoint references or negative sentences in As-Parenthetical constructions.

Response Particles to Would You Mind Questions

Mija Kim(김미자) 담화·인지언어학회 2020 담화와 인지 Vol.27 No.1

This study is primarily intended to explore the various functions of response particles in would you mind polar questions, arguing against the syntactic analysis to polar questions under the assumption that they always have propositional meaning and a full sentential structure. In addition, I show that this would you mind polar question has two characteristics, a biased implication and a negative neutralization. Adopting discourse semantic analysis as a method to analyze this question type, this study attempts to provide a more persuasive explanation on the unique characteristics of response particles to would you mind questions. Focusing on the discourse functions of the response particles that respond to this question type, I demonstrate that two alternatives exist for construing the answer particles: one is to satisfy or fail to satisfy the preparatory condition of the requests, and the other is to accept or reject the indirect request. These discourse functions cause the same effect of negative neutralization in the would you mind questions. This study adds that response markers, such as sure and of course, which are used in the would you mind polar question, show their properties originating from lexical meanings as acceptance markers of requests and conforming markers.

Can’t Seem to Verb Construction in English

Mija Kim 서울대학교 인지과학연구소 2023 Journal of Cognitive Science Vol.24 No.4

This study addresses the can’t seem to verb construction from a perspective of Construction Grammar. The most salient issue in this construction is the mismatch between the syntactic structure and its meaning. This construction has the superficial syntactic form corresponding to the linear order of can, not, seem, even though its interpretation is derived from a combination of seem, can, not. A variety of analyses in previous literature focus on whether these three elements are compositional, resulting in an idiomatic expression or not. This study aims to identify the syntactic and semantic properties of this construction with the help of raw frequency and collostructional analyses. Focusing on the results presented, the study argues that this construction forms its own unique construction with the prototypical meaning of representing a speaker’s mild feeling of frustration regarding either the lack of ability or improbability of finding something successfully, which is derived from this syntactic form. This interpretation is supported by collostructional analysis. In addition, this study provides a variety of characteristics of this construction.

Responses to English Split Interrogatives

Mija Kim(김미자) 현대문법학회 2019 현대문법연구 Vol.103 No.-

This study deals with the discourse functions of the response particles in a split interrogative (hereinafter, SI), thereby contributing to effectively identifying the characteristics of the tag part in SI. I provide a piece of evidence, through the corpus data, that the tag part must be a non- wh -question and essentially functions as a biased polar question. The data tell us that the interlocutors can choose whether to use the SI or a regular question. Through the data that the speakers select a regular question, this paper tries to provide the evidence. In the process of analyzing their functions in SI, this study demonstrates that these particles must have a referential scope in picking up their antecedents in the previous question: a wide or narrow scope in referring to their antecedents. This characteristic leads us to identify the biased property of the tag question, therefore arguing that this tag must be a biased polar question. In the course of these works, we figured out that the addressees apparently take three strategies to respond to the split interrogative: to respond only the wh -question, the tag part, or both.