온산만의 퇴적물과 총알고둥(Littorina brevicula)내 중금속 분포

이인숙,박경숙,최병래,송미연 이화여자대학교 환경문제연구소 1997 이화환경연구 Vol.1 No.-

To investigate the distribution of heavy metal concentrations in Onsan bay, concentrations of cadmium, copper, zinc and lead in surface sediments and the periwinkles (Littorina brevicula) were determined in February and July, 1996. The ranges of cadmium, copper, zinc, and lead concentrations in the surface sediments were 0.08∼3.72, 3∼307, 49∼1273 and 15∼399㎍/g dry weight, respectively. The decrease of concentration in heavy metals with distance from Daejeong stream indicated that this stream is the pollutant source of heavy metals in Onsan Bay. The concentrations of cadmium, copper, zinc and lead in L. brevicula were 0.11∼11.81, 21∼212, 30∼96 and 0.26∼4.12㎍/g dry weight in February and 1.01∼24.9, 66∼325.4, 54∼225 and 0.68∼8.41㎍/g dry weight in July, respectively. These concentrations in L. brevicula were the significantly different(p<0.001) with the season of sampling. However, overall distribution of concentrations of heavy metals in L. brevicula had very similar tendency that concentrations of heavy metal decreased with the distance from the pollutant source irrespective of the two seasons. Therefore, L.brevicula is considered as a useful indicator for heavy metals pollution. According to analysis of the organs, tissues such as the digestive gland, gill and viceral mussel accumulate high concentrations of heavy metals.

부산시 사하구 주민들의 을숙도 주변 환경에 대한 인식도 조사

이상준,박미연 부산대학교 환경문제연구소 1994 環境硏究報 Vol.12 No.-

Over the past '70's, our country has carried out a series of economic development plans successfully. On the other hand, however, as side-effects of industrialization, it has caused so many problems, the most serious one of which is environmental pollution. Therefore, this study, considered the vital state of environmental pollution and the importance of environmental reservation today, is performed through the experimentation and questionaires to have a through grasp of the real environmental state around Eulsuk-do located in Hadan-dong, Saha-gu, Pusan and to make it more comfortable circumstance. The subjects are dwellers living around Eulsuk-do and its regional administrative officials. The result are as follows; 1. General Water Analysis This experiment was carried out to evaluate the water quality of Nagdong river around Eulsuk-do. Water samples were collected from 3 stations from December 1993 to February 1994 (see Fig. 1). Water temperature, pH, chloride ion, DO, BOD, COD, SS were observed to evaluate the water quality. The month average concentration of general items at each site was 8.3∼11.0(℃) in temperature, 6.70∼7.61 in pH, 0.05∼1.32(%) in ??, 9.1∼10.8(mg/l) in DO, 3.33∼7.00(mg/l) in BOD, 6.02∼21.04(mg/l) in COD, 18.0∼65.3(mg/l) in SS. 2. Survey Analysis They pointed out in the questionaires over the state of its natural environment that it is badly contaminated mainly by water pollution(Regional administrative officials : male 88.6%, female 90.5% ; Dwellers : male 94.6%, female 100%). In the question of living environment, they replied that air pollution, water pollution, noise, vibration and stinky small are seriously excessive, and that the remarkable fact of its living environment is that surrounding s of Eulsuk-do are changed into the resort for recreation. And they pointed out the social and cultural environment around Eulsuk-do is insecure, dirty uncomfortable and low-cultured.

Q 열에 의한 감염성 심내막염 2예

문수연,최영실,박미연,이정아,정미경,정혜숙,정두련,송재훈,백경란 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

Q fever is a zoonosis caused by Coxiella burnetii, Presenting as acute and chronic illness and it has been reported worldwide. Acute Q fever is usually asymptomatic or mild and self-limiting, but infective endocarditis is one of the most serious complications of chronic Q fever and can be fatal. Known risk factors for Q fever endocarditis are valvular heart disease, immunocompromised hosts, and pregnancy. There have been some reports on Q fever in Korea but there exists no report on Q fever endocarditis. We have experienced 2 cases of Q fever with underlying valvular heart disease; both Patients came to the hospital for evaluation of prolonged fever. Although Q fever and Q fever endocarditis are rare in Korea, Q fever endocarditis should be considered in the differential diagnosis of patient with infective endocarditis when causative microorganism cannot be identified.

A Sporadic Outbreak of Human Brucellosis in Korea

Mi-Yeoun Park,Chang-Seop Lee,Young-Sil Choi,Seoung-Ju Park,Joo-Sun Lee,Heung-Bum Lee 대한의학회 2005 Journal of Korean medical science Vol.20 No.6

Current Status of Human Brucellosis in Korea (2002-2004)

Mi-Yeoun Park 대한수의학회 2004 대한수의학회 학술대회발표집 Vol.2004 No.-

Comparison between Pediatric Crohn’s Disease and Ulcerative Colitis at Diagnosis in Korea: Results from a Multicenter, Registry-Based, Inception Cohort Study

( Sowon Park ),( Ben Kang ),( Seung Kim ),( Sujin Choi ),( Hyo Rim Suh ),( Eun Sil Kim ),( Ji Hyung Park ),( Mi Jin Kim ),( Yon Ho Choe ),( Yeoun Joo Lee ),( Jae Hong Park ),( Eell Ryoo ),( Hong Koh ) 대한소화기기능성질환·운동학회 2022 Gut and Liver Vol.16 No.6

Background/Aims: We aimed to compare the differences in pediatric Crohn’s disease (CD) and ulcerative colitis (UC) at diagnosis in Korea. Methods: This was a multicenter, registry-based, inception cohort study conducted at five centers in Korea between 2013 and 2017. Baseline demographics, clinical characteristics, and results from laboratory, endoscopic, radiologic examinations were compared between pediatric CD and UC patients who were <19 years old at diagnosis. Results: A total 307 patients were included (227 CD [73.9%] and 80 UC [26.1%]). The male to female ratio was 2.49:1 for CD, and 1.49:1 for UC (p=0.019). Median age at diagnosis was 14.4 years (interquartile range, 12.4 to 16.2) for CD, and 14.4 years (interquartile range, 11.7 to 16.5) for UC (p=0.962). Hematochezia was the only dominant symptom in UC patients compared to CD patients (86.2% vs 30.8%, p<0.001). White blood cell counts, platelet counts, erythrocyte sedimentation rate, and C-reactive protein levels were significantly higher, and serum albumin level was significantly lower in CD patients than in UC patient. Anti-Saccharomyces cerevisiae antibody was positive in 44.5% and 16.2% of CD and UC patients, respectively (p<0.001), and antineutrophil cytoplasmic antibody was positive in 15.0% and 58.8% of CD and UC patients, respectively (p<0.001). Terminal ileal involvement was prominent in CD, while rectal involvement was more prominent in UC. Small bowel involvement and perianal perforating diseases were also more prominent in CD. Conclusions: This is the first a multicenter study in Korea to compare the differences between pediatric CD and UC at diagnosis in Korea. A large-scale, national study is expected to better clarify these findings in the future. (Gut Liver 2022;16:921-929)

Wolbachia infection according to geographical location in Aedes albopictus (Diptera: Culicidae) in Korea

Chan Hee Park,HyungWoo Lim,HyunWoo Kim,Mi Yeoun Park,Wook-Kyo Lee,Jong Yul Roh,Kyu Sik Chang,E-Hyun Shin 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.10

The intracellular endosymbiont bacterium Wolbachia is currently considered the most abundant in arthropods. Many Wolbachia manipulate host reproductive systems, it lead to male-killing, cytoplasmic incompatibility, parthenogenesis and feminization of genetic males with large impact on host ecology and evolution in arthropods. In this study, we investigated the distribution of Wolbachia infection in Ae. albopictus according to geographical distribution. We selected 9 areas and collected Ae. albopictus, these areas were distinguished with mountain chain and waterway. Whole genomic DNA were extracted from collected specimens and PCR analysis were accomplished in each specimen using Wolbachia specific primers such as 16S and WSP genes. As a results, we collected 730 Ae. albopictus at least 30 specimens in each area. Wolbachia infection rate showed different patterns between geographical region. Cheonbook, Cheonnam and Yeongdong showed 100% infection rate followed by Jeju (97%), Chungchung (88%), and Gyungnam (85%) with two Wolbachia marker genes. Our results indicated that Ae. albopictus are commonly infected with Wolbachia, it is possible that Wolbachia may act as endosymbiont in Ae. albopictus regardless of geographical region. Although, low infection rate of Wolbachia, we need continuous survey for the evaluation of Wolbachia strain within Ae. albopictus as a vector of dengue fever.

Ticks and Severe Fever with Thrombocytopenia Syndrome (SFTS)

Jungsang Ryou,Sun-Whan Park,Bong Gu Song,E-Hyun Shin,Seok-Min Yun,Myung-Guk Han,Ye-ji Lee,Mi Yeoun Park,Chan Park 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.04

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging disease, causing high fever, thromobocytopenia, leukopenia, gastrointestinal simptoms (vomiting, diarrhea), hemorrhage and multiorgan dysfunction. It was known that Haemaphysalis longicornis (H. longicornis), a major tick in Korea, is the principal vector for severe fever with thrombocytopenia syndrome virus (SFTSV). Firstly, to investigate the existence and prevalence of SFTSV in the country, we collected the ticks in 9 provinces in South Korea and detected SFTSV from H. longicornis ticks from 2011 to 2012. And we also investigated SFTSV infection in ticks collected from healthy humans without SFTS symptom and their residential areas. From the former study, we collected 13,053 ticks, and H. longicornis (90.8%, 11,856/13,053) was the most abundant among them. The minimum infection rate (MIR) of SFTSV in H. longicornis was 0.5% (59 pools). From the later study, totally 422 ticks of 8 species were collected from humans and at their neighborhood throughout the nation from May to October, 2013 and SFTSVs were detected from 12 pools (5.7% MIR) by RT-PCR. Finally, we diagnosed 35 patients by detecting SFTSV gene with their sera, and isolated 26 SFTSVs among them in 2013. These findings indicate that SFTSVs are prevalent and SFTS is probably endemic in Korea.

Repellency of Three Essential Oil Major Constituents to Wild Adult Anopheles kleini

Dae-Hyun Yoo,Seong Yoon Kim,Mi Yeoun Park,E-Hyun Shin,Wook-Gyo Lee,Jong Yul Roh,Kyu-Sik Chang 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.04

Repellency of 20 plant essential oils to malaria main vector in the Republic of Korea (ROK), Anopheles kleini, was evaluated using skin direct contact bioassay. Anopheles kleini showed the highest repellency to Pelargonium graveolens with EC50 value of 0.244 mg/cm2, followed by Pinus sylvestris and Cinnamomum camphora with EC50 values of 0.484 mg/cm2 and 0.862 mg/cm2. The lowest repellency of An. kleini was revealed from Clary sage oil with EC50 value of 4.665 mg/cm2. Anopheles kleini did not demonstrated any repellency to Lemon, Orange, Neem, Coconut and Olive oil over 20 mg/cm2. Major repellent constituents of Geranium, Pine and Camphora oil were analyzed and identified using Mass-data, GC and GC-Mass. Major constituent of Geranium were β-citronellol (37.0%) and Camphora, 1,8-cineole (35.8%) and Pine, α-terpineol (39.5%). Anopheles kleini showed higher repellency to β-citronellol and 1,8-cineole than to DEET and IR3535 and did not showed any repellency to sabinene and γ-eudesmol over 20 mg/cm2. Residual repellent time of 1,8-cineole and β-citronellol were 26 and 41 min, respectively and DEET, 84 min and IR3535, 102 min. In the light of global efforts to reduce the level of highly toxic synthetic repellents, the three essential oils and their major constituents described merit further study as potential biorepellents for the control of An. kleini populations

Wing Variation and Molecular Identification of Culex orientalis (Diptera: Culicidae)

Hyunwoo Kim,Jong Yul Roh,Mi-Yeoun Park,E-Hyun Shin 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.05

Culex orientalis is belonging to the mimeticus group of the genus Culex and shows various patterns of white pale spots on the wing and wing venation which cause an ambiguity to identify as this species. To confirm whether or not these variations are limited within the species, we observed 230 Cx. orientalis specimens collected in Korea and divided them into 51 variations according to their wing spots patterns. To compare a molecular similarity between the variations, the ITS2 regions of five major variations were analyzed. The results showed that there are more than 97% nucleotide sequence similarity between the variations as well as within a variation. This results suggest that the wing variations of Cx. orientalis are limited a within-species divergence. To further confirm, ITS2 regions of other species (Cx. mimeticus and Cx. jacksoni) in the mimetiucs group will be analyzed and compared with those of Cx. orientalis variations.