Teriparatide therapy for bisphosphonate-related osteonecrosis of the jaw associated with dental implants.

Doh, Re-Mee,Park, Hye-Jeong,Rhee, Yumie,Kim, Hyun Sil,Huh, Jisun,Park, Wonse Published for the International Congress of Oral I 2015 Implant dentistry Vol.24 No.2

<P>This report describes a case of teriparatide (TPTD) therapy for bisphosphonate (BP)-related osteonecrosis of the jaw induced after implant placement. A 75-year-old woman taking oral BP was referred with uncontrolled osteonecrosis of the mandible related to the implant placement. With conservative treatment, BP was suspended and daily subcutaneous injections of 20 μm/d TPTD were started. After 4 months of the therapy, fixture removal and sequestrectomy were performed. Histological analysis revealed necrotic lamellar bone and empty osteocytic lacunae. In contrast, multiple irregular reversal lines of the lamellar bone and active osteoblasts were noted adjacent to the lesion. There was a significant increase in serum C-terminal telopeptide cross-link of type 1 collagen and serum osteocalcin after commencement of the therapy. After 7 months off therapy, the serum levels of the 2 markers remained at a high level compared with the baseline.</P>

Full mouth rehabilitation of a patient with Sturge-Weber syndrome using a mixture of general and sedative anesthesia

Doh, Re-Mee,Yu, Tae-min,Park, Wonse,Kim, Seungoh The Korean Dental Society of Anesthsiology 2015 Journal of Dental Anesthesia and Pain Medicine Vol.15 No.3

Issues related to the control of seizures and bleeding, as well as behavioral management due to mental retardation, render dental treatment less accessible or impossible for patients with Sturge-Weber syndrome (SWS). A 41-year-old man with SWS visited a dental clinic for rehabilitation of missing dentition. A bilateral port-wine facial nevus and intraoral hemangiomatous swollen lesion of the left maxillary and mandibular gingivae, mucosa, and lips were noted. The patient exhibited extreme anxiety immediately after injection of a local anesthetic and required various dental treatments to be performed over multiple visits. Therefore, full-mouth rehabilitation over two visits with general anesthesia and two visits with target-controlled intravenous infusion of a sedative anesthesia were planned. Despite concerns regarding seizure control, bleeding control, and airway management, no specific complications occurred during the treatments, and the patient was satisfied with the results.

Dislodgement resistance of modified resin-bonded fixed partial dentures utilizing tooth undercuts : an in vitro study

Doh, Re-Mee,Lee, Keun-Woo 대한치과보철학회 2009 The Journal of Advanced Prosthodontics Vol.1 No.2

STATEMENT OF PROBLEM. Over the years, resin-bonded fixed partial dentures (RBFPDs) have gone through substantial development and refinement. Several studies examined the biomechanics of tooth preparation and framework design in relation to the success rate of RBFPDs and considered retention and resistance form essential for increase of clinical retention. However, these criteria required preparations to be more invasive, which violates not only the original intentions of the RBFPD, but may also have an adverse effect on retention due to loss of enamel, an important factor in bonding. PURPOSE. The object of this in vitro study was to compare the dislodgement resistance of the new types of RBFPDs, the conventional three-unit fixed partial denture, and conventional design of RBFPD (Maryland bridge). MATERIAL AND METHODS. Fifty resin mandibular left second premolars and second molars were prepared on dentiforms, according to the RBFPD design. After model fabrication (five group, n = 10), prostheses were fabricated and cemented with zinc phosphate cement. After cementation, the specimens were subjected to tensile loading at a cross head speed of 4 mm/min in a universal testing machine. The separation load was recorded and analyzed statistically using one-way analysis of variance followed by Duncan's multiple range test. RESULTS. Group Ⅴ, the pin-retained RBFPDs had the highest mean dislodgement resistance, whereas specimens of group Ⅱ, the conventional RBFPDs, exhibited a significantly lower mean dislodgement resistance compared to the other 4 groups (P<.05). There were no significant differences between group Ⅰ, Ⅲ, and Ⅳ in terms of dislodgement resistance (P>.05). Group V had the highest mean MPa (N/mm²) (P<.05). There was no significant difference between groups Ⅰ, Ⅱ, Ⅲ and Ⅳ (P>.05). CONCLUSION. Within the limits of the design of this in vitro study, it was concluded that: 1. The modified RBFPDs which utilizes the original tooth undercuts and requires no tooth preparation, compared with the conventional design of RBFPDs, has significantly high dislodgement resistance (P<.05). 2. The modified RBFPDs which utilizes the original tooth undercuts and requires minimal tooth preparation, compared with the conventional FPDs, has significantly no difference in retention and dislodgement resistance)(P>.05). 3. The pin-retained FPDs showed a high dislodgement resistance compared to the conventional three-unit FPDs (P<.05).

Foreign body aspiration during dental treatment under general anesthesia: A case report

Doh, Re-Mee The Korean Dental Society of Anesthsiology 2019 Journal of Dental Anesthesia and Pain Medicine Vol.19 No.2

Foreign body aspiration in dental clinics is the most common cause of respiratory emergencies. There are no reports on foreign body aspiration during dental treatment under stable general anesthesia because the patient neither has voluntary movements nor reflex actions. This is a case report on the fall of a prosthesis in the larynx, which occurs rarely under general anesthesia. During the try-in procedure, the prosthesis slid from the surgeon's hand and entered the retromylohyoid space, and while searching for it, it passed down the larynx to the endotracheal tube balloon, leading to a dangerous situation. The prosthesis was promptly removed using video-assisted laryngoscope and forceps, and the patient was discharged without any complications.

Postoperative irradiation after implant placement: A pilot study for prosthetic reconstruction

Doh, Re-Mee,Kim, Sungtae,Keum, Ki Chang,Kim, Jun Won,Shim, June-Sung,Jung, Han-Sung,Park, Kyeong-Mee,Chung, Moon-Kyu The Korean Academy of Prosthodonitics 2016 The Journal of Advanced Prosthodontics Vol.8 No.5

PURPOSE. On maxillofacial tumor patients, oral implant placement prior to postoperative radiotherapy can shorten the period of prosthetic reconstruction. There is still lack of research on effects of post-implant radiotherapy such as healing process or loading time, which is important for prosthodontic treatment planning. Therefore, this study evaluated the effects of post-implant local irradiation on the osseointegration of implants during different healing stages. MATERIALS AND METHODS. Custom-made implants were placed bilaterally on maxillary posterior edentulous area 4 weeks after extraction of the maxillary first molars in Forty-eight Sprague-Dawley rats. Experimental group (exp.) received radiation after implant surgery and the other group (control) didn't. Each group was divided into three sub-groups according to the healing time (2, 4, and 8 week) from implant placement. The exp. group 1, 2 received 15-Gy radiation 1 day after implant placement (immediate irradiation). The exp. group 3 received 15-Gy radiation 4 weeks after implant placement (delayed irradiation). RESULTS. The bone mineral density (BMD) was significantly lower in the immediate irradiation groups. BMD was similar in the delayed irradiation group and the control group. The irradiated groups exhibited a lower bone-to-implant contact ratio, although the difference was not statistically significant. The irradiated groups also exhibited a significantly lower bone volume and higher empty lacuna count than the control groups. No implant failure due to local irradiation was found in this study. CONCLUSION. Within the limits of this study, the timing of local irradiation critically influences the bone healing mechanism, which is related to loading time of prostheses.

Delayed paresthesia of inferior alveolar nerve after dental surgery: case report and related pathophysiology

Doh, Re-Mee,Shin, Sooil,You, Tae Min The Korean Dental Society of Anesthsiology 2018 Journal of Dental Anesthesia and Pain Medicine Vol.18 No.3

Paresthesia is an altered sensation of the skin, manifesting as numbness, partial loss of local sensitivity, burning, or tingling. The inferior alveolar nerve (IAN) is the third branch of the trigeminal nerve and is very important in dental treatment. IAN paresthesia may occur after various dental procedures such as simple anesthetic injections, surgical procedures, and endodontic treatment, and is reported to range from 0.35% to 8.4%. The altered sensation usually follows immediately after the procedure, and reports of late onset of nerve involvement are rare. This report presents a rare case of delayed paresthesia after dental surgery and discusses the pathophysiology of IAN delayed paresthesia.

홍채분석에 나타난 스트레스링과 스트레스와의 상관관계

도영미(Doh Young-mee) 한국자연치유교육학회 2021 자연치유교육학회지 Vol.5 No.1

본 연구는 스트레스와 스트레스의 대표적인 호르몬계, 신경계, 자율신경계, 면역계, 순환계 부조화 질환의 신호인 스트레스링과 자율신경환의 상관관계 연구이다. 연구는 경기도 Y시에 소재한 남, 여 전체 35명을 대상으로 조사하였으며, 치유진단 도구의 일부분인 홍채카메라로 분석하여 스트레스의 단계를 알고, 맥파측정기를 활용하여 맥파 측정과 구조화된 설문지를 통해 스트레스 상태를 확인하여 홍채분석이 형태학적 변화에 적용되는 부분을 비교 연구하였다. Y시에 소재한 남,여 전체 35명을 연구한 결과 스트레스 변수간의 상관관계에서 모두 유의한 정적상관을 나타내었고, 스트레스 설문지의 신체적, 행동적, 정서적, 인지적 결과와 맥파 측정 수치는 유의한 부적상관관계를 나타내었으며, 스트레스 설문지의 신체적, 행동적, 정서적, 인지적 결과와 홍채분석의 스트레스링 개수와의 상관관계에서도 유의한 부적상관관계를 나타내었다. 또한, 스트레스의 각 요인 및 맥파측정, 홍채진단의 상호 연관성은 연관성이 있는 것으로 나타났다. 결론적으로 스트레스를 받으면 스트레스상태가 홍채에 전달되어 홍채 조직의 변화를 일으켜 섬유조직의 분리가 나타나 병소 싸인이나 다른 특징들을 만들어 표시됨을 알 수 있었다. 이를 통해 홍채진단이 정신적, 육체적 건강을 증진 시킬 수 있을 것과 예방의학으로써의 가치를 기대 해 본다. This study is focused on the correlation between stress and the autonomic nervous system, which is a signal of stress and hormonal system, nervous system, autonomic nervous system, immune system, and circulatory disorder, which are representative diseases of stress. This study was conducted on a total of 35 men and women located in Y-city, Gyeonggi-do, and analyzed with the iris camera, which is a part of the healing diagnosis tool, to know the stage of stress. By understanding the condition, the part where the iris analysis is applied to the morphological change was comparatively studied. As a result of studying a total of 35 men and women located in Y city, all of the correlations between stress variables showed significant positive correlations. also it showed the difference between the physical, behavioral, emotional and cognitive results of the stress questionnaire with the pulse wave measurement values. There was a significant negative correlation with the difference in the iris stress analysis. Each factor of stress and the correlation between pulse wave measurement and iris diagnosis were found to be related. In conclusion, when stressed, the stress state is transmitted to the iris, causing changes in the iris tissue, resulting in the separation of fibrous tissue, which is indicated by creating lesion signs and other features. Through this, it is expected that iris diagnosis can improve mental and physical health and its value as a preventive medicine.

Postoperative irradiation after implant placement: A pilot study for prosthetic reconstruction.

Re-Mee Doh,Sungtae Kim,Ki Chang Keum,Jun Won Kim,June-Sung Shim,Han-Sung Jung,Kyeong-Mee Park,Moon-Kyu Chung 대한치과보철학회 2016 The Journal of Advanced Prosthodontics Vol.8 No.5

PURPOSE. On maxillofacial tumor patients, oral implant placement prior to postoperative radiotherapy can shorten the period of prosthetic reconstruction. There is still lack of research on effects of post-implant radiotherapy such as healing process or loading time, which is important for prosthodontic treatment planning. Therefore, this study evaluated the effects of post-implant local irradiation on the osseointegration of implants during different healing stages. MATERIALS AND METHODS. Custom-made implants were placed bilaterally on maxillary posterior edentulous area 4 weeks after extraction of the maxillary first molars in Forty-eight Sprague-Dawley rats. Experimental group (exp.) received radiation after implant surgery and the other group (control) didn’t. Each group was divided into three sub-groups according to the healing time (2, 4, and 8 week) from implant placement. The exp. group 1, 2 received 15-Gy radiation 1 day after implant placement (immediate irradiation). The exp. group 3 received 15-Gy radiation 4 weeks after implant placement (delayed irradiation). RESULTS. The bone mineral density (BMD) was significantly lower in the immediate irradiation groups. BMD was similar in the delayed irradiation group and the control group. The irradiated groups exhibited a lower bone-toimplant contact ratio, although the difference was not statistically significant. The irradiated groups also exhibited a significantly lower bone volume and higher empty lacuna count than the control groups. No implant failure due to local irradiation was found in this study. CONCLUSION. Within the limits of this study, the timing of local irradiation critically influences the bone healing mechanism, which is related to loading time of prostheses.

분산 및 다중 연결형태를 지원하는 광대역 가입자 액세스망의 요구사항

도윤미(Yoon Mee DOH),손승원(Sung Won SOHN),최준균(Jun Kyun CHOI) 대한전자공학회 1992 대한전자공학회 학술대회 Vol.1992 No.4

흉선종 절제술 후 발생한 미세변화병 1예

도화미 ( Fa Mee Doh ),장선정 ( Seon Jung Jang ),구향모 ( Hyang Mo Koo ),김은진 ( Eun Jin Kim ),신혜선 ( Hye Sun Shin ),한승혁 ( Seung Hyeok Han ),강신욱 ( Shin Wook Kang ),최규헌 ( Kyu Hun Choi ),유태현 ( Tae Hyun Yoo ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.4

We report a case of patient with malignant thymoma, who developed nephrotic syndrome several years after thymectomy. This 38-year-old man was diagnosed as myasthenia gravis and malignant thymoma and underwent thymectomy in 2004. Tumor resection and systemic chemotherapy were performed after recurrence in pleura in 2006. He also took pyridostigmine to control his symptoms of myasthenia gravis after thymectomy. Four years later, even though there was no evidence of recurrence of thymoma, he developed a nephrotic syndrome and was diagnosed as a minimal change disease on renal biopsy. After pulse therapy with methylprednisolone followed by oral administration of prednisolone therapy, nephrotic syndrome was improved.