6면 프리즘 렌즈가 장착된 Lensmeter에서 시험 렌즈의 편심 위치 계산

Maria Lin,박종대,,조창호,김현규 배재대학교 자연과학연구소 2005 自然科學論文集 Vol.16 No.1

6면 프리즘 렌즈가 장착된 렌즈메터에서 상점의 위치로부터 시험렌즈의 편심의 위치를 알아 낼 수 있는 알고리즘을 개발하였다. 6개의 프리즘에 의해 형성되는 6개의 상점은 시험렌즈의 편심의 극좌표에 의해 변하게 되며, 비틀린 광선 추적으로 계산할 수 있다. 광학 설계 프로그램인 Code V를 사용하여 렌즈메터 광학계를 분석하고, 시험렌즈의 위치에 따른 상점의 위치 변화를 함수로 나타내서 역으로 상점의 위치로부터 시험렌즈의 편심의 위치를 알아낼 수 있는 방법을 개발하였다. We have developed an algorithm to determine the decenter position from the image points in a lensmeter with 6-sided prism lens. The positions of the image points which are formed by six prisms depends on the decenter position of a test lens and can be calculated by skew ray tracing. The optical characteristics of the lens meter was analyzed using the Code V program and the positions of the image points was expressed as a function of the decenter position of the test lens. By minimizing the expectation error, we can determine the decenter position of a test lens from the image positions.

Reconstructed Human Skin with Hypodermis Shows Essential Role of Adipose Tissue in Skin Metabolism

Jäger Jonas,Vahav Irit,Thon Maria,Waaijman Taco,Spanhaak Bas,de Kok Michael,Bhogal Ranjit K.,Gibbs Susan,Koning Jasper J. 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.3

Background: Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, reconstructed human skin (RhS) models lack the metabolic potential of native human skin, thereby limiting their relevance to study human healthy and diseased skin. We aimed to determine whether incorporation of an adipocyte-containing hypodermis into RhS improves its metabolic potential and to identify major metabolic pathways up-regulated in adipose-RhS. Methods: Primary human keratinocytes, fibroblasts and differentiated adipose-derived stromal cells were co-cultured in a collagen/fibrin scaffold to create an adipose-RhS. The model was extensively characterized structurally in two- and three-dimensions, by cytokine secretion and RNA-sequencing for metabolic enzyme expression. Results: Adipose-RhS showed increased secretion of adipokines. Both RhS and adipose-RhS expressed 29 of 35 metabolic genes expressed in ex vivo native human skin. Addition of the adipose layer resulted in up-regulation of 286 genes in the dermal-adipose fraction of which 7 were involved in phase I (CYP19A1, CYP4F22, CYP3A5, ALDH3B2, EPHX3) and phase II (SULT2B1, GPX3) metabolism. Vitamin A, D and carotenoid metabolic pathways were enriched. Additionally, pro-inflammatory (IL-1β, IL-18, IL-23, IL-33, IFN-α2, TNF-α) and anti-inflammatory cytokine (IL-10, IL-12p70) secretion was reduced in adipose-RhS. Conclusions: Adipose-RhS mimics healthy native human skin more closely than traditional RhS since it has a less inflamed phenotype and a higher metabolic activity, indicating the contribution of adipocytes to tissue homeostasis. Therefore it is better suited to study onset of skin diseases and the effect of xenobiotics. Background: Dysregulation of skin metabolism is associated with a plethora of diseases such as psoriasis and dermatitis. Until now, reconstructed human skin (RhS) models lack the metabolic potential of native human skin, thereby limiting their relevance to study human healthy and diseased skin. We aimed to determine whether incorporation of an adipocyte-containing hypodermis into RhS improves its metabolic potential and to identify major metabolic pathways up-regulated in adipose-RhS. Methods: Primary human keratinocytes, fibroblasts and differentiated adipose-derived stromal cells were co-cultured in a collagen/fibrin scaffold to create an adipose-RhS. The model was extensively characterized structurally in two- and three-dimensions, by cytokine secretion and RNA-sequencing for metabolic enzyme expression. Results: Adipose-RhS showed increased secretion of adipokines. Both RhS and adipose-RhS expressed 29 of 35 metabolic genes expressed in ex vivo native human skin. Addition of the adipose layer resulted in up-regulation of 286 genes in the dermal-adipose fraction of which 7 were involved in phase I (CYP19A1, CYP4F22, CYP3A5, ALDH3B2, EPHX3) and phase II (SULT2B1, GPX3) metabolism. Vitamin A, D and carotenoid metabolic pathways were enriched. Additionally, pro-inflammatory (IL-1β, IL-18, IL-23, IL-33, IFN-α2, TNF-α) and anti-inflammatory cytokine (IL-10, IL-12p70) secretion was reduced in adipose-RhS. Conclusions: Adipose-RhS mimics healthy native human skin more closely than traditional RhS since it has a less inflamed phenotype and a higher metabolic activity, indicating the contribution of adipocytes to tissue homeostasis. Therefore it is better suited to study onset of skin diseases and the effect of xenobiotics.

Verification of Configuration Files using Specially Designed Domain-Specific Language

Matěj Mareček 보안공학연구지원센터 2016 International Journal of Software Engineering and Vol.10 No.10

This paper presents a new domain-specific language (DSL) and its interpreter. The purpose of the language is to be a tool for software developers and administrators that allows them to easily specify how configuration files in INI format should look like and what rules should their contents comply with. The interpreter of the language then takes a specification of a configuration file written in the DSL and verifies whether configuration files given as an input match the specification. The requirement for the language emerged at CERN (European Organization for Nuclear Research). The reason is that CERN, one of the biggest research organizations in the world, heavily uses SCADA (Supervisory Control and Data Acquisition) software for their industrial and scientific machines and SCADA developers needed to be able to verify that configuration files used by CERN's SCADA (WinCC Open Architecture) software are correct and comply with CERN standards. The newly designed DSL is primarily based on declarative paradigm and its core capabilities can be extended by JavaScript code injection. The language syntax is also a superset of INI files syntax so it feels familiar to people who want to use it for simple verification use cases. As for the interpreter, it uses Xtext-based parser to create abstract syntax trees and to integrate with the Eclipse Platform. The execution of the DSL code then uses a hybrid architecture which combines AST interpretation, translation of certain parts of AST into a JavaScript code and running JavaScript code on top of the Java Virtual Machine.

Negative neuromuscular and functional repercussion of forced swimming after axonotmesis

Júlia Araújo de Moura,Jaqueline de Morais,Samara Maria Neves Barbosa,Marcílio Coelho Ferreira,Ivo Vieira de Sousa Neto,Hércules Ribeiro Leite,Murilo Xavier Oliveira,Thaís Peixoto Gaiad,Ana Paula Santo 한국운동재활학회 2022 JER Vol.18 No.3

Automatic categorization of chloride migration into concrete modified with CFBC ash

Maria Marks,Daria Józwiak-Niedzwiedzka,Micha A. Glinicki 사단법인 한국계산역학회 2012 Computers and Concrete, An International Journal Vol.9 No.5

The objective of this investigation was to develop rules for automatic categorization of concrete quality using selected artificial intelligence methods based on machine learning. The range of tested materials included concrete containing a new waste material - solid residue from coal combustion in fluidized bed boilers (CFBC fly ash) used as additive. The rapid chloride permeability test - Nordtest Method BUILD 492 method was used for determining chloride ions penetration in concrete. Performed experimental tests on obtained chloride migration provided data for learning and testing of rules discovered by machine learning techniques. It has been found that machine learning is a tool which can be applied to determine concrete durability. The rules generated by computer programs AQ21 and WEKA using J48 algorithm provided means for adequate categorization of plain concrete and concrete modified with CFBC fly ash as materials of good and acceptable resistance to chloride penetration.

Tip and taper compatibility of accessory gutta-percha points with rotary and reciprocating instruments

Streck Júlia Niero Zanatta,Arcaro Sabrina,Ceretta Renan Antônio,Bortoluzzi Eduardo Antunes,Garcia Lucas da Fonseca Roberti,de Almeida Josiane,Kopper Patrícia Maria Poli,Bernardi Anarela Vassen 대한치과보존학회 2023 Restorative Dentistry & Endodontics Vol.48 No.3

Objectives This study was conducted to evaluate and compare the tip and taper compatibility of accessory gutta-percha points (AGPs) with various rotary and reciprocating instruments. Materials and Methods Using a profile analyzer, tip and taper measurements were taken of 10 AGPs of each of the 14 models available from Odous de Deus and the 4 models available from Dentsply-Maillefer. Diameter measurements were taken at 1-mm intervals, from 3 mm from the tip (D3) to 16 mm. Results Based on the mean values obtained, 3-dimensional (3D) models of the AGPs were drawn in Autodesk Fusion 360 and superimposed on 3D models of each instrument selected (Mtwo, Reciproc, RaCe, K3, and ProDesign Logic) to determine the compatibility between the instrument and the AGP. Data corresponding to the tips and tapers of the various AGPs, as well as the tip and taper differences between the AGPs and the instruments, were analyzed using descriptive statistics. The tapers of the AGPs were subject to the American National Standards Institute/American Dental Association No. 57 standard. The Odous de Deus extra-long medium and extra-long extra-medium AGPs were shown to be compatible with Mtwo, K3, and ProDesign Logic instruments with taper 0.06 and tip sizes 25 and 30, while the Dentsply fine and fine medium cones were compatible with Mtwo, RaCe, and K3 instruments with conicity of 0.04 and tip sizes 35 and 40. Conclusions Both the Odous de Deus and Dentsply commercial brands included 2 AGP models with tip (D3) and taper compatibility with Mtwo, RaCe, K3, and/or Prodesign Logic instruments.

Relationship Between Chloroquine or Hydroxychloroquine Use and Hearing Disorders: A Systematic Review and Meta-Analysis

José Maria Renata,Ortega Jéssica da Silva,Baran Jordana Batista Correia,Lüders Débora,Gonçalves Claudia Giglio de Oliveira,Zeigelboim Bianca Simone,Taveira Karinna Veríssimo Meira,Polanski José Fernan 대한청각학회 2024 Journal of Audiology & Otology Vol.28 No.2

Background and Objectives: Chloroquine and its analog hydroxychloroquine are derivatives of 4-aminoquinoline and are regularly used in the treatment of malaria and autoimmune diseases. Among the side effects of these drugs, alterations associated with the auditory system are frequently mentioned. Thus, the aim of this systematic review is to systematically review publications on hearing disorders and chloroquine or hydroxychloroquine use.Materials and Methods: Inclusion criteria were observational or interventional studies on audiological assessment in participants who were using chloroquine or hydroxychloroquine. The methodological quality was independently assessed by two reviewers using the Meta-Analysis of Statistics: assessment and review Instrument. The certainty of the evidence was assessed using the GRADE tool.Results: A total of 1,372 non-duplicate papers were screened, out of which 17 were included in the final qualitative synthesis, and 5 studies in the meta-analysis. The odds ratio for the two subgroups evaluated did not show significance with no heterogeneity between the effects observed between the different diseases (I²=0%) and obtaining the global estimate of 0.76 (95% confidence interval [CI]=0.41–1.39; <i>p</i>>0.05). Despite the inclusion of papers with different disease samples, the heterogeneity observed in the analysis was low (I²= 0%) and prediction interval (95% PI=0.32–1.80; p>0.05) remained close to that estimated by the CI (95% CI=0.41–1.39; <i>p</i>>0.05). The certainty of the evidence assessed by the GRADE tool was considered very low due to the risk of bias, indirect evidence, and imprecision.Conclusions: The findings of this study suggest that the use of chloroquine/hydroxychloroquine is not associated with hearing disorders.

Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine

Andréia Mitidieri,Maria Beatriz Gurian,Ana Paula Silva,Kalil Tawasha,Omero Poli-Neto,Antônio Nogueira,Francisco Reis,Júlio Rosa-e-Silva 대한약침학회 2015 Journal of pharmacopuncture Vol.18 No.4

Objectives: This study used semiology based on traditionalChinese medicine (TCM) to investigate vital energy(Qi) behavior in women with abdominal myofascialpain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvicpain (CPP) secondary to AMPS were evaluated by usinga questionnaire based on the theories of “yin-yang,”“zang-fu”, and “five elements”. We assessed the followingaspects of the illness: symptomatology; specific locationof myofascial trigger points (MTrPs); onset, cause, durationand frequency of symptoms; and patient and familyhistory. The patients tongues, lips, skin colors, and tonesof speech were examined. Patients were questioned onvarious aspects related to breathing, sweating, sleepquality, emotions, and preferences related to color, food,flavors, and weather or seasons. Thirst, gastrointestinaldysfunction, excreta (feces and urine), menstrual cycle,the five senses, and characteristic pain symptoms relatedto headache, musculoskeletal pain, abdomen, andchest were also investigated. Results: Patients were between 22 and 56 years old,and most were married (78%), possessed a elementaryschool (66%), and had one or two children (76%). Themean body mass index and body fat were 26.86 kg/cm2(range: 17.7 — 39.0) and 32.4% (range: 10.7 — 45.7), respectively. A large majority of women (96%) exhibitedalterations in the kidney meridian, and 98% hadan altered gallbladder meridian. We observed majorchanges in the kidney and the gallbladder Qi meridiansin 76% and 62% of patients, respectively. Five of thetwelve meridians analyzed exhibited Qi patterns similarto pelvic innervation Qi and meridians, indicatingthat the paths of some of these meridians were directlyrelated to innervation of the pelvic floor and abdominalregion. Conclusion: The women in this study showed changesin the behavior of the energy meridians, and the pathsof some of the meridians were directly related to innervationof the pelvic floor and abdominal region.

Push-out bond strength and marginal adaptation of apical plugs with bioactive endodontic cements in simulated immature teeth

de Sá Maria Aparecida Barbosa,Nunes Eduardo,Antunes Alberto Nogueira da Gama,Brito Júnior Manoel,Horta Martinho Campolina Rebello,Amaral Rodrigo Rodrigues,Cohen Stephen,Silveira Frank Ferreira 대한치과보존학회 2021 Restorative Dentistry & Endodontics Vol.46 No.4

Objectives This study evaluates the bond strength and marginal adaptation of mineral trioxide aggregate (MTA) Repair HP and Biodentine used as apical plugs; MTA was used as reference material for comparison. Materials and Methods A total of 30 single-rooted teeth with standardized, artificially created open apices were randomly divided into 3 groups (n = 10 per group), according to the material used to form 6-mm-thick apical plugs: group 1 (MTA Repair HP); group 2 (Biodentine); and group 3 (white MTA). Subsequently, the specimens were transversely sectioned to obtain 2 (cervical and apical) 2.5-mm-thick slices per root. Epoxy resin replicas were observed under a scanning electron microscope to measure the gap size at the material/dentin interface (the largest and smaller gaps were recorded for each replica). The bond strength of the investigated materials to dentin was determined using the push-out test. The variable bond strengths and gap sizes were evaluated independently at the apical and cervical root dentin slices. Data were analyzed using descriptive and analytic statistics. Results The comparison between the groups regarding the variables' bond strengths and gap sizes showed no statistical difference (p > 0.05) except for a single difference in the smallest gap at the cervical root dentin slice, which was higher in group 3 than in group 1 (p < 0.05). Conclusions The bond strength and marginal adaptation to root canal walls of MTA HP and Biodentine cement were comparable to white MTA. Objectives This study evaluates the bond strength and marginal adaptation of mineral trioxide aggregate (MTA) Repair HP and Biodentine used as apical plugs; MTA was used as reference material for comparison. Materials and Methods A total of 30 single-rooted teeth with standardized, artificially created open apices were randomly divided into 3 groups (n = 10 per group), according to the material used to form 6-mm-thick apical plugs: group 1 (MTA Repair HP); group 2 (Biodentine); and group 3 (white MTA). Subsequently, the specimens were transversely sectioned to obtain 2 (cervical and apical) 2.5-mm-thick slices per root. Epoxy resin replicas were observed under a scanning electron microscope to measure the gap size at the material/dentin interface (the largest and smaller gaps were recorded for each replica). The bond strength of the investigated materials to dentin was determined using the push-out test. The variable bond strengths and gap sizes were evaluated independently at the apical and cervical root dentin slices. Data were analyzed using descriptive and analytic statistics. Results The comparison between the groups regarding the variables' bond strengths and gap sizes showed no statistical difference (p > 0.05) except for a single difference in the smallest gap at the cervical root dentin slice, which was higher in group 3 than in group 1 (p < 0.05). Conclusions The bond strength and marginal adaptation to root canal walls of MTA HP and Biodentine cement were comparable to white MTA.

Low blood pressure is sustained during subsequent activities of daily living performed after power training in older women

Hélio José Coelho-Júnior,Bruno Rodrigues,Samuel da Silva Aguiar,Ivan de Oliveira Gonçalves,Ricardo Yukio Asano,Maria-Cláudia Irigoyen,Daniele Jardim Feriani,Marco Carlos Uchida 한국운동재활학회 2017 JER Vol.13 No.4