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Evaluation of machinability in milling by controlling chip thickness using NC simulation
Makoto Nikawa,Masato Okada,Hiroki Mori,Yasuhiro Fujii,Minoru Yamashita 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.10
In this study, the machinability of the machining method for controlling chip thickness during the cutting operation was evaluated using simulation based on NC data. A comparative three-dimensional cutting test with a ball end mill was performed using both original and modified NC data. The modified NC data was created for the purpose of controlling the chip thickness generated when cutting with a constant rotation value and changing the feed rate of the original NC data. The results indicated that the actual chip thickness exceeded that of the calculated value although the thickness fluctuation was suppressed. The results revealed that the maximum cutting force and the fluctuation range of cutting force were low, and tool wear after cutting was suppressed using the modified NC data. The application of the method to the cutting of complicated shapes with high removing volume led to reductions in the cutting time by 31 %.
Cutting characteristics of twist drill having cutting edges for drilling and reaming
Masato Okada,Naoki Asakawa,Yusuke Fujita,Makoto Nikawa 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.5
In this study, the cutting characteristics of a drill reamer, which has conventional twist drill cutting edges appended for reaming, wereinvestigated. A drill reamer has three types of cutting edges, whose roles are drilling, semi-finishing, and finishing. The cutting characteristicsof a conventional twist drill were compared to those of the drill reamer. The cutting characteristics were evaluated using the thrustforce, cutting torque, surface roughness, wear behavior of the cutting edges, and cutting edge temperature. The study used a workpiecemade of carbon steel. The temperature of the cutting edge for reaming reached a maximum value of approximately 420°C, even thoughthe depth of the cut was very small. The inner surface roughness with the drill reamer was superior to that with the conventional drill,even under dry and low-speed cutting conditions. The abrasive wear observed on the margin face of the cutting edge used for reaming.
Identification of Trichophyton tonsurans by Random Ampli6ed Polymorphic DNA
Kim, Jeong Aee,Gusmao, Norma Buarque de,Okada, Kaoru,Takaki, Galba Maria de Campos,Fukushima, Kazutaka,Nishimura, Kazuko,Miyaji, Makoto 대한피부과학회 1999 Annals of Dermatology Vol.11 No.3
Background : T. tonsurans is an anthropophilic dermatophyte mostly causing tinea capitis and tinea corporis. In East Asian countries, it has rarely been isolated until now. However, it is necessary for researchers in Asian countries to be more accustomed to T. tonsurans than before because of frequent international sports exchanges nowadays. Objectives : This study was performed to identify T. tonsurans by random amplified polymorphic DNA (RAPD) analysis. Methods : Fifteen strains which were tentatively identified as T. tonsurans in Brazil were identified again by several conventional mycological tests and RAPD analysis. Results : Among 15 Brazilian strains, 3 were identified as T. tonsurans, 8 T. mentagrophytes, 3 T. rubrum and 1 T. raubitschekii by conventional mycological tests. This result was examined again by RAPD analysis. Conclusion : RAPD analysis is considered a rapid and reliable method for identification of T. tonsurans if the procedure is carefully standardized with adequate primers.
Tomoaki Higuchi,Takashi Nakanishi,Kunio Takada,Mitsuyo Matsumoto,Makoto Okada,Hideyuki Horikoshi,Kimihiro Suzuki 대한의학회 2010 Journal of Korean medical science Vol.25 No.9
This report presents the case of a patient demonstrating multicentric Castleman’s disease (MCD) with a lung lesion that was successfully treated with an anti-interleukin-6 receptor antibody, tocilizumab in combination with corticosteroid and tacrolimus. A 43-yr-old female with abnormal shadows on a chest X-ray was referred to the hospital for further examination. She was diagnosed as having MCD based on the characteristic pathology of inguinal lymph node, lung lesions, laboratory data, and undifferentiated arthritis. Corticosteroid and rituximab therapy did not fully ameliorate the symptoms; thus, the therapeutic regimen was changed to include tocilizumab, oral corticosteroid and tacrolimus. This regimen resulted in clinical remission and the dose of tocilizumab and corticosteroid could be tapered. Tocilizumab in combination with corticosteroid and tacrolimus may therefore be a beneficial treatment regimen for lung lesions associated with MCD.