A community-based aquatic exercise program to improve endurance and mobility in adults with mild to moderate intellectual disability

Renée M. Hakim,Michael D. Ross,Wendy Runco3,Michael T. Kane 한국운동재활학회 2017 JER Vol.13 No.1

Maximal strength in the deep back squat correlates with sprinting performance over short distances

Sebastian Möck,René Hartmann,Klaus Wirth,Gregor Rosenkranz,Christoph Mickel 국민체육진흥공단 한국스포츠정책과학원 2018 International Journal of Applied Sports Sciences Vol.30 No.2

Sprinting is characterized by a transition from propulsion via knee extending musculature during initial acceleration towards ischiocrural musculature thereafter. This may lead to a decrease of correlation of the maximal strength in the back squat and sprinting performance with increasing distance. The aim of this investigation was to show the correlation between maximal dynamic force of the extensor chain of the lower limbs and short distance sprinting performance. Therefore, sprinting performance (0-5, 0-10, 0-15, 0-20, 0-25, 0-30m) and one repetition maximum (1RM) of 51 physical education students were determined. Pearson correlation coefficients were calculated and show significant (p < 0.01) correlations for the relationships with the absolute 1RM (r = -0.661 to -0.792) and the relative 1RM (r = -0.648 to -0.739). However, a decrease in correlation over distance was not found. The results show that the maximal strength of lower extremities’ extensors is a basic requirement in short distance sprinting and should be considered in training.

A Simple, Reliable, and Inexpensive Intraoperative External Expansion System for Enhanced Autologous Structural Fat Grafting

Carlo M. Oranges,Mathias Tremp,Barbara Ling,Reto Wettstein,René D. Largo,Dirk J. Schaefer 대한성형외과학회 2016 Archives of Plastic Surgery Vol.43 No.5

External volume expansion of the recipient site by suction has been proposed as a way of improving fat graft survival. The objective of this study was to present an innovative and simple intraoperative external expansion system to enhance small-volume autologous fat grafting (40–80 mL) and to discuss its background and its mechanism of action. In this system, expansion is performed using a complete vacuum delivery system known as the Kiwi VAC- 6000M with a PalmPump (Clinical Innovations). The recipient site is rapidly expanded intraoperatively 10 times for 30 seconds each with a negative pressure of up to 550 mm Hg before autologous fat injection. During this repetitive stimulation, the tissues become grossly expanded, developing macroscopic swelling that regresses slowly over the course of hours following the cessation of the stimulus. The system sets various mechanisms in motion, including scar release, mechanical stimulation, edema, ischemia, and inflammation, which provide an environment conducive for cell proliferation and angiogenesis. In order to maintain the graft construct in its expansive state, all patients are encouraged postoperatively to use the Kiwi three times daily for one minute per session over the course of three days. The handling of this system is simple for both the patients and the surgeon. Satisfactory clinical outcomes have been achieved without significant complications.

Right-sided acute diverticulitis in the West: experience at a university hospital in Argentina

Huatuco René M. Palacios,Pachajoa Diana A. Pantoja,Liaño Julian E.,Molina Héctor A. Picón,Palencia Rafael,Doniquian Alejandro M.,Parodi Matías 대한대장항문학회 2023 Annals of Coloproctolgy Vol.39 No.2

Purpose: In the West, diverticular disease is located mainly in the left colon. However, it can also present in the right colon, with an incidence of 1%–2% in Caucasians. The purpose of this study was to describe our experience in right-sided acute diverticulitis (RD). Methods: In this retrospective study, 410 patients with acute diverticulitis treated from 2013 to 2020 were included in a university hospital in Córdoba, Argentina. Colonic diverticulitis was stratified into 2 groups; RD and left-sided acute diverticulitis. Demographic and clinical variables, laboratory and imaging findings, type of treatment, follow-up, and recurrence were analyzed. Results: Sixteen patients (3.9%) with RD were identified; 62.5% were male and the mean age was 40.7±11.7 years. A total of 81.3% were Caucasian and 18.7% Native American. Significant differences were found between both groups of diverticulitis; patients with RD were younger (P=0.001), with lower BMI (P=0.01), comorbidity rate (P=0.01), Charlson comorbidity index (P=0.02), hospital stay (P=0.01), severity according to the Hinchey classification (P=0.001) and had a lower recurrence rate (P=0.001). There were no significant differences in sex (P=0.95), duration of pain until admission (P=0.05), laboratory findings (P=0.23) and treatment (P=0.34). Conclusion: Conservative treatment predominated in RD, with a lower rate of complications and recurrences, providing data that support conservative therapy as initial treatment in RD in our environment.

Perinatal Immunization With Vaccine-Grade Listeria monocytogenes Provides Protection Against Murine Th2 Airway Inflammation

Sheka Yagub Aloyouni,Charis-Patricia Segeritz,Ashley M. Sherrid,Matthew J. Gold,Daniela I. M. Loeffler,Marie-Renée Blanchet,Bing Cai,Jeremy Hirota,Kelly M. McNagny,Tobias R. Kollmann 대한천식알레르기학회 2014 Allergy, Asthma & Immunology Research Vol.6 No.4

Purpose: Asthma is a chronic respiratory disorder that leads to inflammation and narrowing of the airways. Its global prevalence has attained epidemiclevels and treatment options that reach beyond temporary relief of symptoms are urgently needed. Since the processes leading to clinicallysymptomatic asthma start early in life, we set out to systematically evaluate a neonatal immunotherapeutic based on Listeria monocytogenes (Lm)for the control of allergic sensitization. Methods: We modified Lm to express the model allergen, ovalbumin (OVA), and tested the ability of neonatalimmunization with this strain to control allergic sensitization in a mouse model of OVA-induced asthma. Mice were immunized as newborns withlive or heat killed LmOVA or live Lm, followed 6 weeks later by allergic sensitization with OVA. In order to determine whether the TH1-polarizing effectof this vaccine vector inadvertently may exacerbate development of certain TH1-driven allergic diseases, mice immunized as newborns were assessedin a model of adult hypersensitivity pneumonitis (HP). Results: Both LmOVA and Lm-control vaccines were highly effective in providinglong-lasting protection from airway inflammation after only one immunization given perinatally. Serum antibody levels and lung cytokine productionsuggest that this prophylactic strategy is associated with an allergen specific TH1-dominated response. Specifically, LmOVA vaccinated mice displayedsignificantly elevated OVA-specific serum IgG2a, but no difference in anti-OVA IgE antibodies and only slightly decreased anti-OVA IgG1 antibodies. Importantly, Lm-based neonatal vaccination did not exacerbate Th1/Th17 driven HP, arguing against broad spectrum immune skewing. Conclusions:Our findings highlight the promise of early life Lm-based immunomodulatory interventions as a prophylactic strategy for allergic asthma.

Verification of pollutant creation model at dendromass combustion

Mária Čarnogurská,Miroslav Příhoda,Marcel Koško,René Pyszko 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.12

Results of verification of two mathematical models presenting the creation of three pollutants at wood combustion in a low power pellet boiler are published in this article. The type of boiler used in the experiment was EKO-KARBON ÚSPOR-AUTOMAT with nominal power of 18 kW. Nitrogen oxides, carbon oxide, and total organic carbon were tested. The models elaborated on the basic theory of dimensional analysis. In the first model, the emissions produced in the wood combustion process were described under the condition that the combustion product temperature in boiler outlet is one relevant parameter in the mathematical model. Combustion air volume flow,combustion air temperature, combustion product temperature, boiler power, and wood calorific power are other parameters in the model. The second model describes the mutual coherence of the same pollutants, provided that flame temperature, instead of combustion product temperature, is incorporated into the model. The outputs obtained from both models are subjected to the same combustion conditions.

Pistachio, Pomegranate and Olive Byproducts Added to Sheep Rations Change the Biofunctional Properties of Milk through the Milk Amino Acid Profile

Mücahit Kahraman,Sabri Yurtseven,Ebru Sakar,Aydın Daş,Hamza Yalçın,Gülşah Güngören,Mustafa Ünal Boyraz,İsmail Koyuncu 한국축산식품학회 2023 한국축산식품학회지 Vol.43 No.1

This study was carried out to determine the effects of adding pistachio shell (PIS), pomegranate hull (POM), and olive pulp (OP) to the diet on milk amino acid and fatty acid parameters in Awassi sheep. In the study, 40 head of Awassi sheep, which gave birth at least twice, were used as animal material. Sheep were fed a control diet without added byproducts (CON), rations containing PIS, POM, and OP. Milk amino acid profile was determined by liquid chromatography-tandem mass spectrometry, milk fatty acid gas chromatography-flame ionization detection device. There was a dramatic reduction in alanine, citrulline, glutamine, glutamic acid, glycine, leucine, ornithine and alphaaminoadipic acid in the research groups. In the PIS group, argininosuccinic acid, gammaminobutyric acid, beta-alanine and sarcosine; In the POM group, asparagine, gammaminobutyric acid, beta-alanine, and taurine; In the OP group, a significant positive increase was found in terms of alanine, histidine, gammaminobutyric acid, and taurine amino acids. The applications in the study did not have a statistically significant effect on the ratio of short, medium and long chain fatty acids in milk (p>0.05). In the presented study, it was determined that PIS, POM, and OP, which were added to the sheep rations at a rate of 5%, caused significant changes in the milk amino acid profiles. In this change in milk amino acid profiles, the benefit-harm relationship should be considered.

Arterial Steal to the Penumbra Area in Patients with Acute MCA Occlusion: A Quantitative Angiographic Analysis

René van den Berg,Jenna J. Wildeman,Olvert A. Berkhemer,Rogier V. Immink,Henk A. Marquering,Charles B.L.M. Majoie,Dagmar Verbaan,Ed T. van Bavel 대한신경중재치료의학회 2020 Neurointervention Vol.15 No.3

Purpose: In acute middle cerebral artery (MCA) occlusion, collateral vessels provide retrograde supply to the occluded territory. We hypothesized that such collateral flow reduces perfusion of the non-occluded donor region (steal effect).Materials and Methods: Patients with an MCA occlusion with opacification of both ipsi- and contralateral anterior cerebral arteries (ACA) on angiography prior to endovascular treatment were selected. Arteriovenous transit time (AVTT) for both ACA territories was compared for different grades of collateral supply to the MCA territory. In addition, the influence of diabetes and hypertension was analyzed. After successful revascularization, AVTT was re-assessed to determine reversibility.Results: Forty-one patients were analyzed. An AVTT of 8.6 seconds (standard deviation [SD] 2.4 seconds) was seen in the ACA territory of the affected hemisphere in comparison to 6.6 seconds (SD 2.1 seconds) for the contralateral side (P<0.001). A more prolonged (but not significant) AVTT was seen in cases with a higher collateral grade. No difference in AVTT was seen in patients with diabetes or hypertension. After successful MCA revascularization, AVTT delay was 7.4 seconds (SD 2.1 seconds).Conclusion: A cerebral steal effect occurs in patients with an acute MCA occlusion, probably related to augmented flow to the penumbra area.

Determination of permeability and inertial resistance coefficient of filter inserts used in the cleaning of natural gas

Mária Čarnogurská,Miroslav Příhoda,Tomáš Brestovič,Jiří Molínek,René Pyszko 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.1

The article describes a methodology for determination of permeability and inertial resistance coefficient of filter inserts used for the separation of solid and liquid impurities in natural gas. The parameters of the filter inserts are described by analytical relations and their real values are obtained experimentally. The realized experiment was focused on the measurement of the pressure drop in the insert, with which both permeability and inertial resistance coefficient were possible to be expressed. The experiment was performed on the reduced physical model of the filter separator, which was constructed at a scale of 1:127. During the experimental measuring the working medium was pressure air. In a real filter separator there is compressed natural gas used as the working medium. The reduced model, therefore, had to meet the basic requirement of similarity of flowing in the model and the real object, which was based on equality of the Reynolds criteria for the work and the model.

Potential Effect of Vortioxetine on Restless Leg Syndrome

Yasemin Hoşgören Alıcı,Müge Kuzu Kumcu 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.3

Restless legs syndrome (RLS) is a chronic progressive movement disorder characterized by abnormal sensations, especially at rest and at night, as the need and urge to move the lower extremity. It has been reported that RLS severity and frequency increase in patients with anxiety and depression. It has been reported that serotonin-noradrenaline reuptake inhibitors such as venlafaxine and selective serotonin reuptake inhibitors such as citalopram, fluoxetine, paroxetine, and sertraline can cause RLS symptoms. No adverse effects of vortioxetine on RLS have been reported in the literature. In this case series, we report the effect of vortioxetine in patients with RLS with symptoms of depression and anxiety. In this case series, the effect of adding vortioxetine to treatment on RLS symptoms is reported in 7 patients (5 female). After the use of vortioxetine, 5 of 7 patients’ symptoms regressed without the need to start a separate drug for primary movement disorder. In conclusion, we believe that studies should be conducted to investigate the efficacy of vortioxetine in the treatment of RLS. Therefore, randomized controlled studies are needed to determine the effect and safety of vortioxetine on RLS symptoms.