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Structural and optical characterization of InGaN/GaN quantum wells grown in cubic phase by MBE
Luis Faustino MEJIA-CUELLAR,Yenny Lucero CASALLAS-MORENO,Alberto PIEDRA-LORENZANA,Carlos Alberto HERNANDEZ-GUTIE,Dagoberto CARDONA,Saul ARIAS-CERON,Juan HERNANDEZ-ROSAS,Jose Luis HERRERA-PEREZ,Emmanue 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8
Personal Privacy Management for Common Users
Susana Alcalde Bagues,Luis A. Ramon Surutusa,Mikel Arias,Carlos Fernandez-Valdivielso,Ignacio R. Matias 보안공학연구지원센터 2009 International Journal of Smart Home Vol.3 No.2
In this work, we introduce the Privacy Manager, a user interface designed to allow non-expert users to manage privacy in the envisioned era of pervasive computing. The Privacy Manager is part of the implementation of the User-centric Privacy Framework, which was introduced as a novel mechanism to enable personal privacy for the inhabitants of the smart home. The Privacy Manager interface incorporates a set of application parts designed especially to meet the requirements of user friendliness, and privacy awareness, with the goal of making privacy management an affordable task for common users. Our first prototype allows to: i) customize permissions for the disclosure of their personal data, ii) control active and passive interactions with services, iii) define obligations to be negotiated on the usage of the data, upon transmission, iv) be aware of privacy related issues such as granted and denied permissions, v) apply alternative privacy mechanisms to access control, as white lying and obfuscation, vi) adhere to enterprise privacy policies based on a contractual relationship with an enterprise or organization. Providing people with tools to control their privacy is critical to guarantee the success of pervasive computing.
Gloria Alicia Pérez-Arias,Iran Alia-Tejacal,María Teresa Colinas-León,Luis Alonso Valdez-Aguilar,Clara Pelayo-Zaldívar 한국원예학회 2019 Horticulture, Environment, and Biotechnology Vol.60 No.3
The tuberose ( Polianthes tuberosa L.) is an ornamental plant native to Mexico with fl owers that are popular due to theirdelicate beauty and intense fragrance. However, as a plant resource, it has not been well studied or commercialized. If properlymanaged and/or exploited, this cut fl ower crop has the potential to further develop and expand the Mexican ornamentalhorticultural industry. At present, few studies have focused on increasing its relatively short shelf-life, which lasts about7–10 day postharvest. As a result, this review focuses on basic aspects of the cut fl ower’s physiology, biochemistry, waterrelations, and postharvest fl oral opening. Also included are its response to cooling, the implementation of diff erent packingstrategies, the application of pulsing, preservative, and hydrating solutions, and the use of 1-methylcyclopropene as aninhibitor of ethylene action. A thorough analysis of all these technologies, their mode of action, and their infl uence on thephysiological response of cut tuberose is essential for the improvement of postharvest management strategies. It is hopedthat both handlers and distributors can benefi t from this information and be successful in prolonging the shelf-life of thisvaluable ornamental resource.
Leal Pinto Sandra Milena,Muehlmann Luis Alexandre,Ojeda Lucía Liliana Mantilla,Vera Arias Angélica María,Cordero Martha Viviana Roa,Santos María de Fátima Menezes Almeida,Azevedo Ricardo Bentes,Rivero 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.2
Background: Photodynamic therapy (PDT) using chloroaluminium phthalocyanine (ClAlPc) and paromomycin sulfate (PM) can be effective against New World Leishmania species involved in cutaneous leishmaniasis (CL). The aim of this study is to assay the skin permeation and the antileishmanial effects of a nanoemulsion (NE) containing both ClAlPc and PM in experimental CL by Leishmania (Viannia) braziliensis. Material and Methods: Cremophor ELP/castor oil-based NEs were prepared by a low-energy method and characterized for their physicochemical parameters. The NEs were used to deliver both ClAlPc and PM to leishmania cells. The in vitro toxicity of NEs were tested in vitro against L. (V.) braziliensis and THP-1 cells. The in vivo toxicity was assessed in non-infected BALB/c mice. Ex-vivo permeation and retention studies using healthy mice skin were also conducted. Finally, the in vivo activity of NE-PM+ClAlPc after PDT was tested in BALB/c mice infected with parasites. Results: NEs are colloidally stable with average droplet diameter of 30 nm, polydispersity index (PDI) below 0.2, and zeta potential near zero. Both promastigotes and intracellular amastigotes treated with NE-PM, NE-ClAlPc and NE-PM+ClAlPc were inhibited at >50%, >95%, >88%, respectively, after PDT with a phototoxic index (PI) >1.2. No skin ClAlPc permeation was observed. In contrast, PM skin permeation was 80-fold higher using PMloaded NE formulation in comparison to aqueous PM solution. Topical treatment with NE formulations showed no signs of local toxicity or genotoxicity. In addition, concentrations of PM between 27.3 - 292.5 μM/25 mg of tissue were detected in different organs. In vivo, the NE-PM+ClAlPc treatment did not reduce skin lesions. Conclusion: The Cremophor ELP/castor oil NE formulation increases the permeation of PM through the skin and can be used to co-deliver PM plus ClAlPc for combined PDT protocols. However, the lack of efficacy in the in vivo model evidences that the therapeutical scheme has to be improved.
Excessive Weight and Obesity Are Associated to Intra-Ventricular Asynchrony: Pilot Study
Nydia Ávila-Vanzzini,Cyntia Zulema Machain Leyva,Luis Eduardo Rodríguez Castellanos,José Antonio Arias Godínez,María Eugenia Ruiz Esparza,Hector Herrera Bello 한국심초음파학회 2015 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.23 No.2
Background: Excessive weight and obesity (EwO) are independent factors in the development of heart failure; they lead toa state of myocardiopathy via inflammatory and hormonal mechanisms. If excessively accumulated, epicardial fat favors a proinflammatorystate. Ventricular asynchrony is a marker of heart failure progression and has been poorly studied in EwO. Theobjective was evaluate the relation between epicardial fat, body mass index (BMI) and mechanical synchrony measured byechocardiography, in healthy individuals with EwO. Methods: We included 55 healthy individuals between the ages of 18 and 35, 17 had a BMI < 25 kg/m2 (30.9%) and 38 had aBMI > 25 kg/m2 (EwO group) (69.09%), anthropometric measurements, transthoracic echocardiogram and synchrony evaluationwere obtained. Results: Left atrial volume, telediastolic and telesystolic left ventricular volumes and the baseline volume of the right ventriclewere greater in the EwO group (20 mL/m2 vs. 15 mL/m2, p = 0.001; 106 mL vs. 82 mL, p = 0.0149 vs. 32 mL, p = 0.001 and34 mm vs. 31 mm, p = 0.02, respectively). The Yu index also correlated with epicardial fat, r = 0.53, p < 0.01, whereby thegreater the amount of epicardial fat, the greater the dispersion timing of ventricular activation. The systolic synchrony index alsocorrelated with the BMI, p = 0.01. Conclusion: Mechanical intraventricular asynchrony is associated to EwO and the amount of epicardial fat; hence, asynchronymay be one more factor leading to heart failure in EwO individuals.
Prognostic Factors and Decision Tree for Long-Term Survival in Metastatic Uveal Melanoma
Daniel Lorenzo,María Ochoa,Josep Maria Piulats,Cristina Gutiérrez,Luis Arias,Jaume Català,María Grau,Judith Peñafiel,Estefanía Cobos,Pere Garcia-Bru,Marcos Javier Rubio,Noel Padrón-Pérez,Bruno Dias,Jo 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4
Purpose The purpose of this study was to demonstrate the existence of a bimodal survival pattern in metastatic uveal melanoma. Secondary aims were to identify the characteristics and prognostic factors associated with long-term survival and to develop a clinical decision tree. Materials and Methods The medical records of 99 metastatic uveal melanoma patients were retrospectively reviewed. Patients were classified as either short ( 12 months) or long-term survivors (> 12 months) based on a graphical interpretation of the survival curve after diagnosis of the first metastatic lesion. Ophthalmic and oncological characteristics were assessed in both groups. Results Of the 99 patients, 62 (62.6%) were classified as short-term survivors, and 37 (37.4%) as long-term survivors. The multivariate analysis identified the following predictors of long-term survival: age 65 years (p=0.012) and unaltered serum lactate dehydrogenase levels (p=0.018); additionally, the size (smaller vs. larger) of the largest liver metastasis showed a trend towards significance (p=0.063). Based on the variables significantly associated with long-term survival, we developed a decision tree to facilitate clinical decision-making. Conclusion The findings of this study demonstrate the existence of a bimodal survival pattern in patients with metastatic uveal melanoma. The presence of certain clinical characteristics at diagnosis of distant disease is associated with long-term survival. A decision tree was developed to facilitate clinical decision-making and to counsel patients about the expected course of disease.
Julio Cesar Magalhães,Mariana Gongora,Renan Vicente,Juliana Bittencourt,Guaraci Tanaka,Bruna Velasques,Silmar Teixeira,Gledys Morato,Luis F. Basile,Oscar Arias-Carrión,Fernando A.M.S Pompeu,Mauricio C 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.1
Objective: The present study sought to analyze the influence of Levetiracetam (LEV) in cognitive performance by identifying the changes produced by LEV in reaction time, in neuropsychological assessment of attention and memory and in absolute theta power in frontal activity. Methods: Twelve healthy subjects (5 men and 7 women; mean age, 30.08 years, standard deviation, 4.71) were recruited for this study. The neuropsychological tests: Trail Making Test (A and B), Digit Span (direct and indirect numerical orders/working memory); Stroop test (inhibitory control of attention); Tower of London (planning and decision-making) and a quantitative electroencephalography were applied in 2 different days after and before the participants ingested the capsule of placebo or 500 mg LEV. Results: A two-way-ANOVA was implemented to observe the interaction between conditions (placebo or LEV 500 mg) and moments (pre- and post-ingestion of LEV or placebo). The data were analyzed by the SPSS statistical package (p<0.05). For the neuropsychological parameter, the Trail Making Test (A) was the only test that showed significant difference for condition in the task execution time (p=0.026). Regarding the reaction time in the behavioral parameter, an interaction between both factors (p=0.034) was identified through a two-way-ANOVA (condition versus moment). Electrophysiological measures showed a significant interaction for electrodes: F7, F3, and FZ. Conclusion: The findings showed that LEV promotes an important cognitive enhancement in the executive functions.
Pleural effusion secondary to minoxidil in a peritoneal dialysis patient
Palomar, Rosa,Morales, Pedro,Sanz de Castro, Saturnino,Tasis, Ana,Rodrigo, Emilio,Piñ,era, Celestino,Ruiz, Juan Carlos,Ferná,ndez-Fresnedo, Gema,Martin de Francisco, Angel Luis,Arias, Manu Oxford University Press 2004 Nephrology, dialysis, transplantation Vol.19 No.10