Preventive Effects of Colon Colitis in Balb/c Mice by Doenjang Prepared with Starters and Bamboo Salts

Fang-Fang Liu,Min-kyeng Choi,Min-Woo Jeong,Kun-Young Park 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

Anticancer Effects of Kochujang (Korean fermented red pepper paste) on Azoxymethane (AOM)/Dextran Sulfate Sodium (DSS) Induced Colitis-related Colon Cancer in C57BL/6J Mice

Fang-Fang Liu,Jae-Hoon Seo,Kun-Young Park 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

Kochujang (Korean fermented red pepper paste) Attenuates High Fat Diet-Induced Obesity by Regulating Lipid Metabolism

Fang-Fang Liu,Jae-Hoon Seo,Jeung-Ha Kil,Kun-Young Park 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

Studies on Development of Preparation Method of Black Soybean Chungkukjang

Fang-Fang Liu,Min-kyeng Choi,Min-Woo Jeong,Kun-Young Park 한국식품영양과학회 2013 한국식품영양과학회 학술대회발표집 Vol.2013 No.11

가격복잡성, 소비자혼란 및 쇼핑피로감에 기반한 온라인 호텔 예약 지연

류팡팡(Fang-Fang Liu),설훈구(Hoon-Ku Sul) 한국관광학회 2024 관광학연구 Vol.48 No.2

중국에서 지속적으로 증가하고 있는 모바일 호텔예약 앱들은 사용자들에게 폭넓은 숙박 옵션과 다양한 가격대를 제공하나, 가격의 복잡성과 정보 과다로 인해 사용자의 혼란을 야기하고 결정을 미루게 만들고 있다. 이에 대응하여, 모바일 예약 서비스 제공자들은 소비자의 혼란을 완화하고 예약 절차를 단순화하여 소비자 만족도를 높이고 장기적인 소비자 유지를 도모할 수 있는 전략을 개발하고 실행할 필요성이 대두되고 있다. 이러한 배경에서 이 연구는 중국 모바일 호텔예약 앱 서비스 환경에서 가격복잡성, 소비자혼란, 쇼핑피로감 및 구매지연 사이의 영향관계를 살펴보았으며, 특히 이러한 영향 관계에서 쇼핑피로감의 매개효과, 예약경험의 조절효과와 조절된 매개효과에 대해 실증적 검정을 수행하였다. 연구를 위해 중국 모바일 호텔예약 앱을 이용하여 호텔을 예약한 경험이 있는 사용자를 대상으로 온라인 설문 조사를 진행하였으며, 305명의 유효한 표본을 최중 분석에 활용하였다. 연구 결과, 첫째, 중국 모바일 호텔예약 앱 서비스의 가격복잡성과 소비자혼란은 모두 쇼핑피로감과 구매지연에 유의한 정적 영향을 미친 것으로 나타났다. 둘째, 소비자의 쇼핑피로감이 구매지연에 정적 영향을 미치며, 가격복잡성, 소비자혼란, 및 구매지연 사이의 관계에서 쇼핑피로감이 부분적 매개효과를 가지는 것으로 확인되었다. 마지막으로, 소비자혼란과 구매지연 간의 관계에서 예약경험이 조절역할과 조절된 매개역할을 수행한다는 점이 밝혀졌다. 이러한 연구 결과는 호텔예약 앱이 가격 정보의 명확성과 비교의 용이성을 향상시켜야 하며, 사용자 맞춤형 서비스와 신속한 반응으로 소비자의 혼란과 피로감을 경감시키는 전략이 필요함을 제시한다. 이 연구는 호텔예약 분야의 이해와 지식을 확장하고 실질적인 문제의 해결 방안을 마련하는 데 있어 중요한 기여를 할 것으로 기대된다. In China, the rapid expansion of mobile hotel reservation apps has led to an information overload, resulting in pricing complexity, user confusion, and subsequent booking delays. In the context of mobile hotel booking app services in China, this study empirically examined the relationships between price complexity, consumer confusion, shopping fatigue, and purchase delay. Additionally, it also tested the mediating effect of shopping fatigue and both the moderating and the moderated mediation effects of reservation experience on these relationships. To this end, an online survey targeting Chinese consumers with an experience of booking hotels using mobile apps in China was carried out, and a total of 305 valid responses were analyzed. The key findings are as follows. Firstly, both the price complexity and consumer confusion exerted positive impacts on shopping fatigue and purchase delay. Secondly, shopping fatigue positively impacted purchase delay. Furthermore, shopping fatigue partially mediated the relationship between price complexity, consumer confusion, and purchase delay. Finally, reservation experience significantly influenced the relationship between consumer confusion and purchase delay, serving as a moderating factor and as a moderated mediating factor. The findings of this study can help enrich the understanding and knowledge base in the hotel reservation domain and devise practical and effective solutions to tackle related challenges.

Identification of QTLs associated with the anaerobic germination potential using a set of Oryza nivara introgression lines

Licheng Liu,Xiaoxiang Li,Sanxiong Liu,Jun Min,Wenqiang Liu,Xiaowu Pan,Baohua Fang,Min Hu,Zhongqi Liu,Yongchao Li,Haiqing Zhang 한국유전학회 2021 Genes & Genomics Vol.43 No.4

Background Rice (Oryza sativa L.) is an important crop and a staple food for half of the population around the world. The recent water and labor shortages are encouraging farmers to shift from traditional transplanting to direct-seeding. However, poor germination and slow elongation of the coleoptile constrains large-scale application of direct-seeding. Objective Thisstudy was aimed to investigate the genetic basis of the anaerobic germination(AG) potential using a set of Oryza nivara (O. nivara) introgressionlines (ILs). Methods Inthis study, a total of 131 ILs were developed by introducing O. nivara chromosomesegments into the elite indica rice variety 93-11 through advanced backcrossingand repeated selfng. A high-density genetic map has been previouslyconstructed with 1,070 bin-markers. The seeds of ILs were germinated and usedto measure coleoptile length under normal and anaerobic conditions. QTLsassociated with AG potential were determined in rice. Results Basedon the high-density genetic map of the IL population, two QTLs, qAGP1 and qAGP3 associated with AG tolerance were characterized and locatedon chromosomes 1 and 3, respectively. Each QTL explained 15% of the phenotypic variance.Specifcally, the O. nivara-derived chromosomesegments of the two QTLs were positively tolerance to anaerobic condition byincreasing coleoptile length. In a further analysis of public transcriptomedata, a total of 26 and 36 genes within qAGP1 and qAGP3 were transcriptionallyinduced by anaerobic stress, respectively. Conclusions Utilizationof O. nivara-derived alleles at qAGP1 and qAGP3 can potentially enhance tolerance to anaerobic stress at thegermination stage in rice, thereby accelerating breeding of rice varieties tobe more adaptative for direct-seeding.

Effect of qigong exercise and acupressure rehabilitation program on pulmonary function and respiratory symptoms in patients hospitalized with severe COVID-19: A randomized controlled trial

Shu-ting Liu,Chao Zhan,Yun-jing Ma,Chao-yang Guo,Wei Chen,Xiao-ming Fang,Lei Fang 한국한의학연구원 2021 Integrative Medicine Research Vol.10 No.-

Background There are several effective complementary and integrative therapies for patients with severe COVID-19. The trial aims to evaluate the efficacy and advantages of the qigong exercise and acupressure rehabilitation program (QARP) for treating patients with severe COVID-19. Methods A total of 128 patients with COVID-19 aged 20 to 80 years were recruited and randomly allocated in a 1:1 ratio to receive QARP plus standard therapies or standard therapies alone. QARP consisted of acupressure therapy and qigong exercise (Liu Zi Jue). The primary outcome was measured with the modified Medical Research Council (mMRC) dyspnea scale, and the secondary outcomes included the modified Borg dyspnea scale (MBS), fatigue Scale-14 (FS-14), patient health questionnaire-9 scale (PHQ-9), duration of respiratory symptoms, and vital signs. Results In total, 128 patients completed the clinical trial. The QARP group and standard therapies group showed significant improvements in vital signs (except blood pressure) and clinical scales compared with baseline (p<0.05). The QARP group also showed more significant improvement in the mMRC dyspnea scale (-1.8 [-2.1, -1.6], p=0.018) and modified Borg dyspnea scale (-3.7 [95% confidence intervals (CI) -4.3, -3.1], p=0.045). The duration of cough was 14.3 days (95% CI 12.6, 16.1, p=0.046), and the length of hospital stay was 18.5 days (95% CI 17.0, 20.0, p=0.042) in the QARP group, both of which were significantly reduced compared with the standard therapies group (p<0.05). Conclusion QARP plus standard therapies improved lung function and symptoms such as dyspnea and cough in patients with severe COVID-19 and shortened the length of hospital stay. Therefore, QARP may be considered an effective treatment option for patients with severe COVID-19. Trial registration Clinical Research Information Service Identifier: ChiCTR2000029994 Background There are several effective complementary and integrative therapies for patients with severe COVID-19. The trial aims to evaluate the efficacy and advantages of the qigong exercise and acupressure rehabilitation program (QARP) for treating patients with severe COVID-19. Methods A total of 128 patients with COVID-19 aged 20 to 80 years were recruited and randomly allocated in a 1:1 ratio to receive QARP plus standard therapies or standard therapies alone. QARP consisted of acupressure therapy and qigong exercise (Liu Zi Jue). The primary outcome was measured with the modified Medical Research Council (mMRC) dyspnea scale, and the secondary outcomes included the modified Borg dyspnea scale (MBS), fatigue Scale-14 (FS-14), patient health questionnaire-9 scale (PHQ-9), duration of respiratory symptoms, and vital signs. Results In total, 128 patients completed the clinical trial. The QARP group and standard therapies group showed significant improvements in vital signs (except blood pressure) and clinical scales compared with baseline (p<0.05). The QARP group also showed more significant improvement in the mMRC dyspnea scale (-1.8 [-2.1, -1.6], p=0.018) and modified Borg dyspnea scale (-3.7 [95% confidence intervals (CI) -4.3, -3.1], p=0.045). The duration of cough was 14.3 days (95% CI 12.6, 16.1, p=0.046), and the length of hospital stay was 18.5 days (95% CI 17.0, 20.0, p=0.042) in the QARP group, both of which were significantly reduced compared with the standard therapies group (p<0.05). Conclusion QARP plus standard therapies improved lung function and symptoms such as dyspnea and cough in patients with severe COVID-19 and shortened the length of hospital stay. Therefore, QARP may be considered an effective treatment option for patients with severe COVID-19. Trial registration Clinical Research Information Service Identifier: ChiCTR2000029994

Study on the size dependent constitutive model and the micro-channel forming process for PEMFC

Liu Fang 한국소성가공학회 2006 박판성형 심포지엄 Vol.2006 No.6

Quantification of Nerve Viscosity Using Shear Wave Dispersion Imaging in Diabetic Rats: A Novel Technique for Evaluating Diabetic Neuropathy

Liu Feifei,Li Diancheng,Xin Yuwei,Liu Fang,Li Wenxue,Zhu Jiaan 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.2

Objective: Viscoelasticity is an essential feature of nerves, although little is known about their viscous properties. The discovery of shear wave dispersion (SWD) imaging has presented a new approach for the non-invasive evaluation of tissue viscosity. The present study investigated the feasibility of using SWD imaging to evaluate diabetic neuropathy using the sciatic nerve in a diabetic rat model. Materials and Methods: This study included 11 diabetic rats in the diabetic group and 12 healthy rats in the control group. Bilateral sciatic nerves were evaluated 3 months after treatment with streptozotocin. We measured the nerve cross-sectional area (CSA), nerve stiffness using shear wave elastography (SWE), and nerve viscosity using SWD imaging. The motor nerve conduction velocity (MNCV) was also measured. These four indicators and the histology of the sciatic nerves were then compared between the two groups. The performance of CSA, SWE, and SWD imaging in distinguishing the two groups was assessed using receiver operating characteristic (ROC) analysis. Results: Nerve CSA, stiffness, and viscosity in the diabetic group was significantly higher than those in the control group (all p < 0.05). The results also revealed a significantly lower MNCV in the diabetic group (p = 0.005). Additionally, the density of myelinated fibers was significantly lower in the diabetic group (p = 0.004). The average thickness of the myelin sheath was also lower in the diabetic group (p = 0.012). The area under the ROC curve for distinguishing the diabetic neuropathy group from the control group was 0.876 for SWD imaging, which was significantly greater than 0.677 for CSA (p = 0.030) and 0.705 for SWE (p = 0.035). Conclusion: Sciatic nerve viscosity measured using SWD imaging was significantly higher in diabetic rats. The viscosity measured using SWD imaging performed well in distinguishing the diabetic neuropathy group from the control group. Therefore, SWD imaging may be a promising method for the evaluation of diabetic neuropathy.

Preventing Wrong-site Surgeiy by Universal Protocol to Promote Patient Safety

Fang-Chih Yeh,Hsien-Ju Chuang,Han-Ming Chen,Li,Fang Liu,Hsien-Hung Hung 한국간호과학회 2009 한국간호과학회 학술대회 Vol.2009 No.10