NiCoSe4@CFF with excellent properties prepared by microwave method for flexible supercapacitors and oxygen evolution reaction

Lijun Du,Ning Lv,Jiashuai Li,Jiayi Zhang,Yilan Chen,Yalin Zhang,Zhen Li,Xianqiang Huang,Jujie Luo 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.120 No.-

NiCoSe4 nanoflowers were synthesized on carbon fiber felt (CFF) by microwave method, and the effects ofmicrowave time and microwave power on the morphology, physical phase and performance ofNiCoSe4@CFF were explored. The results display that the nanostructured NiCoSe4 prepared under themicrowave irradiation of 1000 W for 120 s is uniformly loaded on the CFF. The NiCoSe4@CFF electrodeexhibits a superior specific capacity of 1653.6F g1 at 1A/g and maintains a superior cycling performanceof 87.05 % of the initial capacitance over 150,000 cycles. In addition, the flexible supercapacitor fabricatedwith NiCoSe4@CFF as the cathode exhibits excellent flexibility and flexural strength. As an effective catalystfor oxygen evolution reaction (OER), NiCoSe4@CFF demonstrates a low overpotential of 0.358 V, arelatively small Tafel slope of 115.93 mV dec1 and an excellent lifetime at 10 mA cm2.

Neuroprotection of Dexmedetomidine against Cerebral Ischemia-Reperfusion Injury in Rats: Involved in Inhibition of NF-κB and Inflammation Response

( Lijun Wang ),( Haiyan Liu ),( Ligong Zhang ),( Gongming Wang ),( Mengyuan Zhang ),( Yonghui Yu ) 한국응용약물학회 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.4

Dexmedetomidine is an α2-adrenergic receptor agonist that exhibits a protective effect on ischemia-reperfusion injury of the heart, kidney, and other organs. In the present study, we examined the neuroprotective action and potential mechanisms of dexmedetomidine against ischemia-reperfusion induced cerebral injury. Transient focal cerebral ischemia-reperfusion injury was induced in Sprague-Dawley rats by middle cerebral artery occlusion. After the ischemic insult, animals then received intravenous dexmedetomidine of 1 mg/kg load dose, followed by 0.05 mg/kg/min infusion for 2 h. After 24 h of reperfusion, neurological function, brain edema, and the morphology of the hippocampal CA1 region were evaluated. The levels and mRNA expressions of interleukin-1b, interleukin-6 and tumor nevrosis factor-α as well as the protein expression of inducible nitric oxide synthase, cyclooxygenase-2, nuclear factor-κBp65, inhibitor of κBα and phosphorylated of κBα in hippocampus were assessed. We found that dexmedetomidine reduced focal cerebral ischemia-reperfusion injury in rats by inhibiting the expression and release of inflammatory cytokines and mediators. Inhibition of the nuclear factor-κB pathway may be a mechanism underlying the neuroprotective action of dexmedetomidine against focal cerebral I/R injury.

Color-Image Guided Depth Map Super-Resolution Based on Iterative Depth Feature Enhancement

( Lijun Zhao ),( Ke Wang ),( Jinjing Zhang ),( Jialong Zhang ),( Anhong Wang ) 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.8

With the rapid development of deep learning, Depth Map Super-Resolution (DMSR) method has achieved more advanced performances. However, when the upsampling rate is very large, it is difficult to capture the structural consistency between color features and depth features by these DMSR methods. Therefore, we propose a color-image guided DMSR method based on iterative depth feature enhancement. Considering the feature difference between high-quality color features and low-quality depth features, we propose to decompose the depth features into High-Frequency (HF) and Low-Frequency (LF) components. Due to structural homogeneity of depth HF components and HF color features, only HF color features are used to enhance the depth HF features without using the LF color features. Before the HF and LF depth feature decomposition, the LF component of the previous depth decomposition and the updated HF component are combined together. After decomposing and reorganizing recursively-updated features, we combine all the depth LF features with the final updated depth HF features to obtain the enhanced-depth features. Next, the enhanced-depth features are input into the multi-stage depth map fusion reconstruction block, in which the cross enhancement module is introduced into the reconstruction block to fully mine the spatial correlation of depth map by interleaving various features between different convolution groups. Experimental results can show that the two objective assessments of root mean square error and mean absolute deviation of the proposed method are superior to those of many latest DMSR methods.

A Study of the Effect of Work-Family Culture on Employee Work-Family Enrichment

Zhang, Lijun(장려군),Chung, Soo-Jin(정수진) 한국경영교육학회 2018 경영교육연구 Vol.33 No.2

[연구목적] 본 연구는 중국의 일반적인 직원들을 대상으로 하여 진행하였다. 연구의 목적은 일-가정 문화가 일-가정 이익에 미치는 영향에 대하여 검증하고, 일-가정 문화가 일-가정 이익에 영향을 미치는 과정에 일몰입의 매개역할과 자기효능감의 조절역할에 대해 검증하는 것이다. [연구방법] 본 연구는 선행연구를 토대로 하여 여섯 개 가설을 제기하였다. 이를 위해 일반적인 직원을 대상으로 설문조사를 실시하였다. 통계분석 프로그램 SPSS 23.0과 AMOS 23.0을 통해 수집된 자료로 가설을 검증하였다. [연구결과] 첫째, 일-가정 문화가 일-가정 이익에 유의적인 영향을 미치는 것으로 확인 되었다. 둘째, 일-가정 문화가 일-가정 이익에 영향을 미치는 과정에서 일몰입의 유의적인 매개효과가 확인되었다. 셋째, 일-가정 문화가 일-가정 이익에 영향을 미치는 과정에서 자기효능감의 조절효과가 확인되었다. [연구의 시사점] 선행연구에서 일-가정 문화와 종업원의 일-가정 관계에 대해 주요하게 일-가정 갈등이라는 부정적인 개념에 치중한 점을 보완하였고 긍정적인 결과에 대한 연구를 충족시켰다. 중국 국내의 기업들에 있어서 긍정적인 시점으로부터 출발하여 종업원의 일-가정 문화가 일-가정 증익에 대한 효과기제와 종업원 개인의 차이를 토대로 하여 일-가정 증익의 실현에 효과적인 방법을 제공한다. [Purpose] This research takes ordinary Chinese employee as the research object. The purpose of the study is to explore the impact of work-family culture on work-family enrichment, and thereby verify the mediating effect of work-engagement and the moderating effect of self-efficacy. [Methodology] Based on the related research, this study proposes six hypotheses. A total of 380 valid questionnaires were collected from the general employee in China by means of a questionnaire. Data were analyzed by using SPSS 23.0 and AMOS 23.0 software. [Findings] Firstly, work-family culture has a significant and direct impact on the employee’s work-family enrichment. Secondly, work-engagement plays a mediating effect in process of influencing by the work-family culture on the work-family enrichment. Thirdly, self-efficacy plays a moderating role in process of influencing by the work-family culture on the work-family enrichment. [Implications] In contrast to past research on work-family culture and employee work-family relations, which mainly focused on the negative aspects of work-family conflicts, the study attempts to enrich the research on positive results.

Chirality detection of amino acid enantiomers by organic electrochemical transistor

Zhang, Lijun,Wang, Guiheng,Xiong, Can,Zheng, Lei,He, Jianbo,Ding, Yunsheng,Lu, Hongbo,Zhang, Guobing,Cho, Kilwon,Qiu, Longzhen Elsevier 2018 Biosensors & bioelectronics Vol.105 No.-

<P><B>Abstract</B></P> <P>Chiral recognition of α-amino acids is attracting increasing interest due to the importance of α-amino acids in protein metabolism as well as in food products and pharmaceuticals. Organic electrochemical transistors (OECTs) with gate electrodes modified with molecularly imprinted polymer (MIP) films were fabricated and successfully used as highly selective and sensitive chiral recognition biosensors for <SMALL>D/L</SMALL>-tryptophan (<SMALL>D</SMALL> <SMALL>/</SMALL> <SMALL>L</SMALL>-Trp) and <SMALL>D/L</SMALL>-tyrosine (<SMALL>D</SMALL> <SMALL>/</SMALL> <SMALL>L</SMALL>-Tyr). The MIP films, which can specifically recognize and has an electrocatalytic effect on the oxidation of Trp and Tyr, together with the amplification function of an OECT, provide a highly sensitive and selective OECT biosensor. The sensor showed a linear response range for <SMALL>L</SMALL>-Trp and <SMALL>L</SMALL>-Tyr from 300 nM to 10 μM with a sensitivity of 3.19 and 3.64 μA/μM, respectivity. And the detection limit for <SMALL>L</SMALL>-Trp and <SMALL>L</SMALL>-Tyr is of 2 nM and 30 nM (S/N > 3). The selectivity factors of <SMALL>L</SMALL>-Trp, <SMALL>D</SMALL>-Trp, <SMALL>L</SMALL>-Tyr and <SMALL>D</SMALL>-Tyr to their enantiomers are 11.6, 3.5, 14.5 and 2.6, respectively. This method can pave the way for widespread applications of OECT-based sensors in chiral material identification.</P> <P><B>Highlights</B></P> <P> <UL> <LI> An novel chiral recognition MIP-OECT sensor was developed. </LI> <LI> The MIP films showed good performance of selective and electro-catalytic oxidation for Trp and Tyr. </LI> <LI> The MIP films together with the amplification function of an OECT afforded a highly sensitive, selective sensor for chirality detection of amino acid enantiomers. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

The Effect of Work-Family Culture on Bidirectional Work-Family Enrichment

Lijun Zhang(장려군),Wenning Li(이문닝) 한국산업경제학회 2018 한국산업경제학회 정기학술발표대회 논문집 Vol.2018 No.12

The phosphodiesterase 5 inhibitor, KJH-1002, reverses a mouse model of amnesia by activating a cGMP/cAMP response element binding protein pathway and decreasing oxidative damage : Recovery of cognitive function by KJH-1002

Zhang, Lijun,Seo, Jae Hong,Li, Huan,Nam, Ghilsoo,Yang, Hyun Ok Wiley (Blackwell Publishing) 2018 British journal of pharmacology Vol.175 No.16

Bulk Nanocrystalline SmCo₅ Permanent Magnet Prepared by Spark Plasma Sintering

Zhang Dongtao,Yue Ming,Zhang Jiuxing,Pan Lijun 한국자기학회 2007 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Neuroprotective Effect of Astersaponin I against Parkinson’s Disease through Autophagy Induction

( Lijun Zhang ),( Jeoung Yun Park ),( Dong Zhao ),( Hak Cheol Kwon ),( Hyun Ok Yang ) 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.6

An active compound, triterpene saponin, astersaponin I (AKNS-2) was isolated from Aster koraiensis Nakai (AKNS) and the autophagy activation and neuroprotective effect was investigated on in vitro and in vivo Parkinson’s disease (PD) models. The autophagy-regulating effect of AKNS-2 was monitored by analyzing the expression of autophagy-related protein markers in SHSY5Y cells using Western blot and fluorescent protein quenching assays. The neuroprotection of AKNS-2 was tested by using a 1-methyl-4-phenyl-2,3-dihydropyridium ion (MPP⁺)-induced in vitro PD model in SH-SY5Y cells and an MPTP-induced in vivo PD model in mice. The compound-treated SH-SY5Y cells not only showed enhanced microtubule-associated protein 1A/1B-light chain 3-II (LC3-II) and decreased sequestosome 1 (p62) expression but also showed increased phosphorylated extracellular signal-regulated kinases (p-Erk), phosphorylated AMP-activated protein kinase (p-AMPK) and phosphorylated unc-51-like kinase (p-ULK) and decreased phosphorylated mammalian target of rapamycin (p-mTOR) expression. AKNS-2-activated autophagy could be inhibited by the Erk inhibitor U0126 and by AMPK siRNA. In the MPP⁺-induced in vitro PD model, AKNS-2 reversed the reduced cell viability and tyrosine hydroxylase (TH) levels and reduced the induced α-synuclein level. In an MPTP-induced in vivo PD model, AKNS-2 improved mice behavioral performance, and it restored dopamine synthesis and TH and α-synuclein expression in mouse brain tissues. Consistently, AKNS-2 also modulated the expressions of autophagy related markers in mouse brain tissue. Thus, AKNS-2 upregulates autophagy by activating the Erk/mTOR and AMPK/mTOR pathways. AKNS-2 exerts its neuroprotective effect through autophagy activation and may serve as a potential candidate for PD therapy.

TNF-α-Induced SOX5 Upregulation Is Involved in the Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Through KLF4 Signal Pathway

Lijun Xu,Lili Zheng,Zhifang Wang,Chong Li,Shan Li,Xuedi Xia,Pengyan Zhang,Li Li,Lixia Zhang 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.6

Postmenopausal osteoporosis (PMOP) is a common sys-temic skeletal disease characterized by reduced bone mass and microarchitecture deterioration. Although differentially expressed SOX5 has been found in bone marrow from ovariectomized mice, its role in osteogenic differentiation in human mesenchymal stem cells (hMSCs) from bone marrow in PMOP remains unknown. In this study, we investigated the biological function of SOX5 and explore its molecular mechanism in hMSCs from patients with PMOP. Our findings showed that the mRNA and protein expression levels of SOX5 were upregulated in hMSCs isolated from bone marrow samples of PMOP patients. We also found that SOX5 overexpression decreased the alkaline phosphatase (ALP) activity and the gene expression of osteoblast markers including Collagen I, Runx2 and Osterix, which were increased by SOX5 knockdown using RNA interference. Furthermore, TNF- notably upregulated the SOX5 mRNA expression level, and SOX5 knockdown reversed the effect of TNF- on osteogenic differentiation of hMSCs. In addition, SOX5 overexpression increased Kruppel-like factor 4 (KLF4) gene expression, which was decreased by SOX5 silencing. KLF4 knockdown abrogated the suppressive effect of SOX5 overexpression on osteogenic differentiation of hMSCs. Taken together, our results indicated that TNF--induced SOX5 upregulation inhibited osteogenic differentiation of hMSCs through KLF4 signal pathway, suggesting that SOX5 might be a novel therapeutic target for PMOP treatment.