Lactobacillus salivarius REN Counteracted Unfavorable 4-Nitroquinoline-1-Oxide-Induced Changes in Colonic Microflora of Rats

Ming Zhang,Xuewei Qiao,Liang Zhao,Lu Jiang,Fazheng Ren 한국미생물학회 2011 The journal of microbiology Vol.49 No.6

Probiotics and carcinogens both have a significant effect on the microfloral composition of the human intestine. The objective of this study was to investigate the impact of an important carcinogen, 4-Nitroquinoline-1- Oxide on colonic microflora and the efficacy of the probiotic Lactobacillus salivarius REN as an agent of counteracting these effects. Using denaturing gradient gel electrophoresis (DGGE) combined with redundancy analysis, we demonstrated that both 4-Nitroquinoline-1-Oxide and L. salivarius REN significantly altered the bacterial communities of rat colons. A total of 27 bacterial strains were identified as being affected by treatment with 4-Nitroquinoline-1-Oxide or L. salivarius REN using a t-value biplot combined with band sequencing. 4-Nitroquinoline-1-Oxide treatment increased the abundance of two potential pathogens (one Helicobacter strain and one Desulfovibrio strain), as well as reducing the abundance of two potentially beneficial strains (one Ruminococcaceae strain and one Rumen bacteria). The Helicobacter strain was initally detected in carcinogen-treated rat intestinal microflora, but L. salivarius REN treatment effectively suppressed the growth of the Helicobacter strain. These results suggested that L. salivarius REN may be a potential probiotic, efficiently acting against the initial infection with, and the growth of pathogenic bacteria.

Experimental and Numerical Investigations of the Seismic Performance of UHPC Box Piers

Liang Ren,Zhi Fang,Rui Zhong,Kai Wang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.2

Experimental studies and numerical simulations were carried out to assess the seismic performance of Ultra High Performance Concrete (UHPC) box piers. The mechanical performance of the specimens under constant axial load and reversed cyclic lateral load were tested at different loading conditions (different angles between applied load and the strong direction of the column cross section which is referred as Test Angle (TA) in this study). The failure mode, hysteretic characteristics, displacement ductility, energy dissipation and stiffness degradation were discussed. A UHPC hysterical constitutive model was proposed by incorporating the UHPC constitutive model and utilizing similar hysteretic rule and integrated into OpenSees. Quasi-static analysis which accounts for the bar slippage at the foot of pier was conducted. The acceptable agreement between the numerical analysis and experimental results proofs the validity of the modeling method. Furthermore, parametric analysis was performed to investigate the effect of axial load ratio, longitudinal reinforcement ratio and TA on the ductility of UHPC box piers. The results indicated that the ductility of UHPC box piers gradually decreases with the increase of longitudinal reinforcement ratio. TA significantly affects the ductility of UHPC box piers and the ductility is the minimum if the lateral loading direction is perpendicular to the diagonal of the cross-section.

Synthesis, Application, and Recovery of Alkali-Clearable Disperse Dyes Containing Azo Pyridone Structure

Liang Jin,Tao Qian,Ren-Liang Wang,Tao Zhu,Wei-Guo Chen,Hua Jiang,Zhi-Hua Cui 한국섬유공학회 2022 Fibers and polymers Vol.23 No.4

Carboxylic acid ester disperse dyes containing an azo pyridone structure have a high molar extinction coefficient,excellent washing color fastness, and simple synthetic methods. Dyes were readily synthesized through a conventional diazocoupling reaction between the reactant ethyl p-aminobenzoate and a coupling component containing an azo pyridonestructure. Subsequently, the molecular structures of the target products were characterized by FTIR, mass spectrometry,1H NMR, 13C NMR, UV-vis absorption spectroscopy, and elemental analysis. The synthesized dyes were used to dyepoly(ethylene terephthalate) fabric, and their washing and rubbing color fastness properties were tested and compared underdifferent post-treatment methods. Moreover, under the condition of alkali clearing, the relationships among different alkaliconcentrations and clearing effects were studied to determine the optimal alkali clearing process conditions for dyed fabrics,and the minimum alkali consumption required to obtain the best results was determined. It was found that carboxylic esterdisperse dyes containing an azo pyridone structure showed good dyeing performance and alkali-clearable properties onpolyester fibers. In addition, in hydrolyzate recovery, BaCl2 (salting out) can be used instead of acidification to recover thedye hydrolyzate, which has good environmental benefits.

Local and nonlocal contents inN-qubit generalized Greenberger-Horne-Zeilinger states

Ren, Chang-Liang,Choi, Mahn-Soo American Physical Society 2010 Physical review. A. Atomic, molecular, and optical Vol.82 No.5

Structural State Detection Using Transmissibility and Non-negative Matrix Factorization

Tongqun Ren,Meiling Hui,Junsheng Liang,Dazhi Wang,Liang He,Yonghang Chen 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.11

Transmissibility function (TF) was used in structural state detection which examined the change of the response-only vibration characteristics. The technology of signal correlation was utilized to obtain the TF between two testing points. Multiple TFs under different states were calculated as basic TFs and formed a state matrix. Subsequently, non-negative matrix factorization (NMF) was performed for the state matrix. Then both the basic and testing TFs were projected to the feature subspace derived from NMF so as to obtain the state feature index vectors, respectively. Finally, the Euclidean distance between state feature index vectors was defined as the state indicator. The experimental results indicated that this method can achieve better detection accuracy than that using magnitude indicator. Actually, a result with 100 percent correct detection was achieved when proper rule of dimensionality reduction was selected. This method is essentially a multivariate statistical process monitoring (MSPM) method. It is feasible in vibration-based structural state detection in the situation where the excitation signals are unavailable or inaccessible.

The Study on Family Language Policy of the Bai People in Yinyuan Town, Yuanjiang County, Yunnan Province

任亮(Ren Liang),刘,代容(Liu Dairong),卢,鹏,(Lu Peng) 아시아사회과학학회 2021 International Science Research Vol.1 No.1

The paper focuses on studying the current situation and inheritance of language use of the endangered ethnic minority — Bai People in Yinyuan Town, Yuanjiang County, Yunnan Province, China. The research adopts semi-structured interviews and questionnaire survey methods. It focuses on collecting 16 groups of Bai families’ family language usage. The study found that the natural inter-generational transmission of Yinyuan Bai language shows a decreasing trend. It is recommended to enhance the vitality of Yinyuan Bai language from both the macro and micro levels, so as to strengthen its inheritance and protection.

Pyoderma Gangrenosum in a Patient with X-Linked Agammaglobulinemia

( Qi Tan Fa-liang Ren ),( Hua Wang ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.4

X-linked agammaglobulinemia (XLA) is a primary im-munodeficiency disorder caused by germline mutations of B-cell tyrosine kinase (BTK) gene. It is characterized by de-creased serum immunoglobulins levels and circulating ma-ture B cells. This defect in humoral immunity leads to in-creased susceptibility to infection. Pyoderma gangrenosum (PG) is an uncommon, ulcerating, neutrophilic dermatosis. Here we report PG in an 8-year-old patient with XLA. The pa-tient received intravenous immunoglobulin treatment in conjunction with prednisone and topical application of 0.03% tacrolimus ointment and the ulcer was almost com-pletely healed in the 2 weeks of follow-up. The coexistence has been rarely reported. XLA may be a possible cofactor in the pathogenesis of PG. (Ann Dermatol 29(4) 476∼478, 2017)

Which Indicator Among Lumbar Vertebral Hounsfield Unit, Vertebral Bone Quality, or Dual-Energy X-Ray Absorptiometry-Measured Bone Mineral Density Is More Efficacious in Predicting Thoracolumbar Fragility Fractures?

Bo Zhang,Lu-Ping Zhou,Xian-Liang Zhang,Dui Li,Jia-Qi Wang,Chong-Yu Jia,Hua-Qing Zhang,Liang Kang,Ren-Jie Zhang,Cai-Liang Shen 대한척추신경외과학회 2023 Neurospine Vol.20 No.4

Objective: Hounsfield units (HU), vertebral bone quality (VBQ), and bone mineral density (BMD) can all serve as predictive indicators for thoracolumbar fragility fractures. This study aims to explore which indicator provides better risk prediction for thoracolumbar fragility fractures. Methods: Patients who have received medical attention from The First Affiliated Hospital of Anhui Medical University for thoracolumbar fragility fractures were selected. A total of 78 patients with thoracolumbar fragility fractures were included in the study. To establish a control group, 78 patients with degenerative spinal diseases were matched to the fracture group on the basis of gender, age, and body mass index. The lumbar vertebral HU, the VBQ, and the BMD were obtained for all the 156 patients through computed tomography, magnetic resonance imaging, and dual-energy x-ray absorptiometry (DEXA). The correlations among these parameters were analyzed. The area under curve (AUC) analysis was employed to assess the predictive efficacy and thresholds of lumbar vertebral HU, VBQ, and BMD in relation to the risk of thoracolumbar fragility fractures. Results: Among the cohort of 156 patients, lumbar vertebral HU exhibited a positive correlation with BMD (p < 0.01). Conversely, VBQ showed a negative correlation with HU, BMD (p < 0.05). HU and BMD displayed a favorable predictive efficacy for thoracolumbar fragility fractures (p < 0.01), with HU (AUC = 0.863) showcasing the highest predictive efficacy, followed by the DEXA-measured BMD (AUC = 0.813). VBQ (AUC = 0.602) ranked lowest among the 3 indicators. The thresholds for predicting thoracolumbar fragility fractures were as follows: HU (88),VBQ (3.37), and BMD (0.81). Conclusion: All 3 of these indicators, HU, VBQ, and BMD, can predict thoracolumbar fragility fractures. Notably, lumbar vertebral HU exhibits the highest predictive efficacy, followed by the BMD obtained through DEXA scanning, with VBQ demonstrating the lowest predictive efficacy.

Robust L<SUB>1</SUB> Filtering with Pole Constraint in a Disk via Parameter-dependent Lyapunov Functions

Liang He,Guang-Ren Duan,Ai-Guo Wu 제어로봇시스템학회 2006 제어로봇시스템학회 국제학술대회 논문집 Vol.2006 No.10

Statistics-based Optimization of Extracellular Polysaccharide Production from Hirsutella sinensis using a Fermentation Process and In vitro Immunomodulatory Activity

Liang He,Jun-Wen Cheng,Yan-Bin Wang,Hai-Bo Li,Hua Qian,Wei-Qi Li,Xue-Yong Ren 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.2

A 3 factor, 3 level Box-Behnken factorialdesign combined with response surface methodology wasused to optimize the fermentation process for production ofextracellular polysaccharide (EPS) from Hirsutella sinensis. The 3 independent variables were temperature (X1), initialpH (X2), and the glucose concentration (X3). Experimentaldata were fitted to a 2nd order polynomial equation usingmultiple regression. The optimal fermentation conditionsof the production of EPS were a temperature of 18.21oC,an initial pH of 5.81, and a glucose concentration of 7.39g/L. The maximum predicted EPS production of 2.41 g/Lwas close to the actual experimental EPS yield (2.42±0.038%), demonstrating the model validity. EPS from H. sinensis had a direct in vitro immuno-stimulating activityusing murine macrophage RAW264.7 cells, and stimulatedrelease of several major cytokines (IL-1β, NF-κB, TNF-α,and iNOS) in a dose-dependent manner.