http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Lian Jiangen,Lian Junfeng,Zhong Mingjin 대한정형외과학회 2020 Clinics in Orthopedic Surgery Vol.12 No.2
To the Editor: With the rapid growth of the use of hip arthroscopy and strong evidence on its clinical efficacy and safety in the treatment of femoroacetabular impingement (FAI), we read with great interest the recent article entitled “Arthroscopic treatment for femoroacetabular impingement with extraspinal diffuse idiopathic skeletal hyperostosis” by Hwang et al.1) To the best of our knowledge, it is the first paper that studied the clinical outcomes of hip arthroscopy in patients with extraspinal diffuse idiopathic skeletal hyperostosis (DISH) that involves the hip joint. This retrospective study suggests that extraspinal DISH involving the hip joint could lead to FAI and arthroscopic treatment could provide good outcomes. The study also emphasizes that FAI patients who have painful hip and limitation of range of motion should also be evaluated to determine whether they have extraspinal DISH involving the hip.1) We really appreciate the excellent work of the authors. However, there are some issues worth to be explored. Ossification with bony overgrowth in extraspinal DISH mostly involves the acetabular rim of the hip joint, which leads to pincer-type FAI. Pincer FAI occurs in two forms: focal and global.2) Focal acetabular overcoverage can exist in the anterosuperior acetabulum (as shown in Fig. 2)1) with a center-edge angle (CEA; Wiberg angle) of 25°–39°. Global FAI has more generalized and typically more extreme acetabular overcoverage, resulting in a CEA of 40° or greater with protrusio acetabuli or coxa profunda2) (as shown in Fig. 1).1) The reduction in CEA is a more important determinant of hip function than is the magnitude of the preoperative or postoperative CEA.3) Therefore, we think the preoperative and postoperative CEAs should have been carefully evaluated in the study. The authors described that the central compartment (CC) of the hip joint was addressed first during the hip arthroscopic surgery. However, because of severe acetabular overcoverage, joint space narrowing, and early stage osteoarthritis (Fig. 1),1) traction is usually very difficult to achieve, and the entry needle access into the CC is often blocked from the anterolateral or anterior portal.4) In this condition, the peripheral compartment (PC) of the hip joint would be explored first as Dienst et al.5) described: the patient is placed on a standard traction table without joint traction and with the hip and knee semiflexed. The entry needle is used for confirmation of entry to the joint by lateral and caudal displacement of the femoral head under fluoroscopy. The PC is easily explored by portal exchange and internal and external rotation of the hip. Then, acetabuloplasty and femoroplasty from PC are performed until sufficient to permit CC access. After PC manipulation, the hip and knee are extended, the CC is addressed with traction. We are convinced that hip arthroscopy for the treatment of patients with extraspinal DISH involving the hip joint will show good clinical results without any intra- or postoperative complications related to the surgical procedure. However, extraspinal DISH is a progressive disease characterized by abnormal calcification and ossification around joints, which may be one of the causes of secondary osteoarthritis. In patients with FAI, older age (>45 years), elevated BMI (>24.5 kg/m2), osteoarthritic changes, and increased CEA are predictors of negative outcomes after hip arthroscopy.6) Obviously, the 17 hips (12 patients) met one or more of those conditions. Therefore, the degree of hip arthritis and rates of revision surgery and conversion to total hip arthroplasty should be assessed in the long term. We look forward to seeing the long-term follow-up outcomes of the study in terms of patients' function, painful symptoms, and complications. We respect the great contribution of the authors and are much interested in the authors' thoughts on these issues.
Wang, Lian-Dong,Gao, Xia,Li, Jun-Ying,Yu, Hong-Yan,Su, Hai-Wen,Liu, Lian-Zhong,Qi, Jun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9
Background: To investigate the effects of preemptive analgesia with parecoxib sodium on haemodynamics and plasma stress hormones in surgical patients with thyroid carcinoma. Materials and Methods: Fifty-seven patients with thyroid carcinoma who underwent thyroidectomy selectively in Laiwu Hospital Affiliated to Taishan Medical University and Binzhou People's Hospital were selected and randomly divided into three groups, 19 cases in each group. The control group was intravenously injected 0.9% sodium chloride injection before anesthesia induction; trial group I was intravenously injected with parecoxib sodium 20 min before anesthesia induction; based on trial group I, trial group II was injected with parecoxib sodium again 12 h after surgery. The levels of plasma norepinephrine (NE), cortisol (Cor) and blood glucose before, 12 and 24 h after surgery and changes of haemodynamics before surgery, at the end of surgery and 12, 24 and 48 h after surgery were compared in the three groups. Besides, visual analogue scale (VAS) scores were recorded 4, 8, 12 and 24 h after surgery. Results: 12 and 24 h after surgery, the levels of plasma NE and Cor in three groups rose dramatically (P<0.05 or (P<0.01); The levels of plasma NE and Cor in trial groups I and II were evidently lower than in control group (P<0.05 or P<0.01), and those in trial group II slightly lower than in trial group I. 12 h after surgery, the heart rates (HR) and systolic pressures (SBP) in trial groups I and II increased obviously by comparison to surgery before (P<0.05 or P<0.01), but gradually returned to the preoperative level. HR, SBP and diastolic pressures (DBP) in trial groups I and II at the end of surgery and 12 h after surgery were all lower than in the control group, and significant differences were present (P<0.05 or (P<0.01). At 4, 8, 12 and 24 h after surgery, VAS scores in trial groups I and II were markedly lower than in the control group (P<0.05 or (P<0.01), the scores in trial group II being the lowest. Conclusions: Combined application of parecoxib sodium for preemptive analgesia before anesthesia and after surgery can effectively reduce the levels of plasma stress hormones and improve analgesic effects in surgical patients with thyroid carcinoma, and without conspicuous impact on haemodynamics.
Lian-feng Wei,Chen Bao,Shi-zhong Wang,Yong Zheng,Meng-bin Zhou 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.8
Low cycle fatigue tests on the hydrogenated welding seam of ZreSneNb alloy at room temperature and 360 C had been carried out by using the funnel-shaped flat specimens. The relationships between nominal stress & strain directly measured across the funnel and local stress & strain at the root of the funnel are given by considering cyclic plasticity correction. The results show that the fatigue resistance of welding seam at room temperature is only slightly better than that at 360 C. Probabilistic fatigue life curves are obtained by using a two-parameter power function.
Lian, Hai-Wei,Zhou, Yun,Jian, Zhi-Hong,Liu, Ren-Zhong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: MicroRNAs, small noncoding RNA molecules, can regulate mammalian cell growth, apoptosis and differentiation by controlling the expression of target genes. The aim of this study was to investigate the function of miR-323-5p in the glioma cell line, U251. Materials and Methods: After over-expression of miR-323-5p using miR-323-5p mimics, cell growth, apoptosis and migration were tested by MTT, flow cytometry and cell wound healing assay, respectively. We also assessed the influence of miR-323-5p on the mRNA expression of IGF-1R by quantitative real-time reverse transcriptase PCR (qRT-PCR), and on the protein levels by Western blot analysi. In addition, dual-luciferase reporter assays were performed to determine the target site of miR-323-5p to IGF-1R 3'UTR. Results: Our findings showed that over-expression of miR-323-5p could promote apoptosis of U251 and inhibit the proliferation and migration of the glioma cells. Conclusions: This study demonstrated that increased expression of miR-323-5p might be related to glioma progression, which indicates a potential role of miR-323-5p for clinical therapy.
Zhong-Liu Zhou,Wen-Qing Yin,Xiao-Peng Zou,Dan-Ying Huang,Cui-Liu Zhou,Lian-Mei Li,Ke-Cheng Chen,Zi-Ying Guo,San-Qing Lin 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.6
The extraction and solvent partition of the leaves ofEucalyptus citriodora, and repeated column chromatography for n-BuOH fraction yielded a new flavonoid glycoside, citrioside C (1),along with three known flavonoid glycosides (2-4). The latter wereidentified with kaempferol-3-O-β-D-glucopyranosyl (12)-α-L-rhamnoside(2), kaempferol-3-O-α-L-rhamnoside (3), and quercetin-3-O-α-Lrhamnoside(4). Their chemical structures were identified on thebasis of spectroscopic data analyses including NMR, MS, UV, andIR. All constitutents were isolated for the first time from the leavesof Eucalyptus citriodora. The potential antivirus activity of all theisolated compounds was evaluated. Compound 4 showed potentantiviral activity against respiratory syncytial virus with 50%inhibition concentration (IC50) value of 1.9 μg/mL and selectiveindex value of 9.8.