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Hee Seok “Andy” Lee,Carolyn U. Lambert,Rob Law 한국관광학회 2011 International Journal of Tourism Sciences Vol.11 No.1
Customer information is critical for hospitality and tourism companies to provide tailored service, but customers may be reluctant to disclose their personal information to the companies. Existing research finds that perceived control is positively related to willingness to disclose, but scant research studies scrutinize its sub-concepts and their relationship with information disclosure. This study decomposed perceived control with perceived cognitive and decisional control and examined their effect on willingness to disclose personal information. The results indicated that when a privacy mechanism was available, perceived cognitive control was more influential to customers’ willingness to disclose than perceived decisional control was. Findings suggest that hospitality and tourism companies that want to collect more customer data need to manipulate customers’ perceived control accordingly regardless of availability of privacy protection mechanisms. Since there have been very limited, if any, prior studies examining perceived control with decomposed cognitive and decisional controls, the model verified in this study serves as a guide for future research.
Effective transduction of osteogenic sarcoma cells by a baculovirus vector
Song, Sun U.,Shin, Seok-Hwan,Kim, Soon-Ki,Choi, Gwang-Seong,Kim, Woo-Chul,Lee, Moon-Hee,Kim, Sei-Joong,Kim, In-Ho,Choi, Mi-Sook,Hong, Young-Jin,Lee, Kwan-Hee Microbiology Society 2003 The Journal of general virology Vol.84 No.3
<P>Efficient gene delivery of a baculovirus-derived vector (BV-p53-lacZ) to a human osteogenic sarcoma cell line, Saos-2, was serendipitously found while evaluating the vector for gene delivery to human p53-null tumour cells in a previous study. Therefore, we investigated other human, rat and mouse osteogenic sarcoma and other types of tumour cell lines for transduction efficiency via baculovirus vectors containing a lacZ reporter gene under the control of either a cytomegalovirus or Rous sarcoma virus promoter. The expression of beta-galactosidase protein, assessed by X-Gal staining and beta-galactosidase ELISA, demonstrated an extremely high level of transduction efficiency in some osteogenic sarcoma cell lines, such as U-2OS, Saos-2 and Saos-LM2. These human osteogenic sarcoma cell lines showed levels of beta-galactosidase expression 5-40 times greater than HepG2 cells, which were previously thought to be the mammalian cells most susceptible to baculovirus-mediated gene delivery. The level of acetylated histone proteins in these tumour lines did not correlate well with the high level of reporter gene expression. These results strongly suggest that some osteogenic sarcoma cells are highly susceptible to baculovirus-mediated gene delivery and that a baculovirus-derived vector is an efficient gene delivery vehicle into human osteogenic sarcoma cells.</P>
( Seung Hui Seok ),( Tae Bin Im ),( Jung U Shin ),( Hee Jung Lee ),( Moon Soo Yoon ),( Dong Hyun Kim ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: Psoriasis is a chronic T17 cells-driven immune-mediated inflammatory disease. However, psoriasis patients may have elevated serum total immunoglobulin E (IgE), which is a hallmark of Th2 inflammation. In previous case reports, patients with psoriasis with high serum IgE levels did not respond well to treatment or exacerbated eczema lesions. Objectives: We sought to investigate the clinical characteristics of psoriasis patients with high serum total IgE levels. Methods: This is a retrospective chart review of 130 patients with plaque psoriasis who had done serum total IgE level test from November 1, 2009, to October 31, 2019. We compared the demographics, clinical characteristics, severity of the disease, and treatment regimen for each high IgE group (>214 U/mL), and normal IgE group (≤214 U/mL). Results: Among 130 patients with psoriasis, 41 patients (31.5%) had high serum IgE level. High IgE levels were positively associated with the severity of disease and psoriasis lesions including scalp, hands, feet, and flexures which are difficult-to-treat were observed significantly higher in patients with high serum IgE level. There was no correlation between age, gender, disease duration, or presence of pruritus, and serum total IgE level. Conclusion: High serum IgE levels in psoriasis may be a prognostic factor which is related with more severe and difficult-to-treat traits requiring systemic treatment.
혈중 총 면역글로불린 E가 증가된 건선 환자의 임상적 특징: 후향적 단일기관 연구
석승휘 ( Seung Hui Seok ),임태빈 ( Tae Bin Im ),신정우 ( Jung U Shin ),이희정 ( Hee Jung Lee ),윤문수 ( Moon Soo Yoon ),김동현 ( Dong Hyun Kim ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.2
Background: Psoriasis is a chronic T17 cell-driven immune-mediated inflammatory disease. However, patients with psoriasis may have elevated total serum immunoglobulin E (IgE) levels, which is a hallmark of Th2 inflammation. In previous case reports, psoriasis patients with elevated total serum IgE levels did not respond well to treatment or had exacerbated eczema lesions. Objective: We sought to investigate the clinical characteristics of psoriasis patients with elevated total serum IgE levels. Methods: This is a retrospective chart review of 130 patients with psoriasis who were tested for total serum IgE levels from November 1, 2009, to October 31, 2019. We compared the demographics, clinical characteristics, disease severity, and treatment regimen for each elevated IgE group (>214 U/mL) and normal IgE group (≤214 U/mL). Results: Among 130 patients with psoriasis, 41 (31.5%) had elevated total serum IgE levels. Elevated total serum IgE levels were positively associated with the severity of disease; psoriasis lesions including those on the scalp, hands, feet, and flexures, which are difficult to treat, were observed to be significantly higher in patients with elevated total serum IgE levels. There was no correlation between age, sex, disease duration, or presence of pruritus and total serum IgE levels. Conclusion: This study identified the clinical characteristics of psoriasis patients with elevated total serum IgE levels in Korea. (Korean J Dermatol 2021;59(2):94∼99)
서우석,이호영 한국정보사회진흥원 2006 정보화정책 Vol.13 No.3
인터넷을 이용한 문화콘텐츠 소비가 증가함에 따라 정보화 과정에서 문화취향이 중요한 요인으로 작용하게 되었다. 이 연구는 정보 불평등에 대한 문화취향의 영향을 이론적으로 규명하고 경험적 자료의 분석을 통해 실증하고자 하였다. 이론적인 논의에서는 정보부자와 정보빈자 사이의 간극에 대한 관심으로부터 출발하였던 정보격차의 문제가 정보화의 진전에 따라 다차원적인 양상을 갖게 되면서 사용격차가 갖는 의미가 커졌음을 제시하였다. 또한 인터넷 사용에 대한 기대편익과 충족감의 순환구조를 통해 인터넷의 사용격차가 구조화될 때 문화취향에 따른 네트워크 효과가 중요한 변수로 작용할 수 있음을 논의하였다. 서울시민을 대상으로 수집한 경험적 자료를 이용하여 분석한 결과 문화취향은 인터넷 이용정도, 인터넷 글쓰기, 인터넷 기대편익에 모두 유의미한 영향을 미치는 것으로 나타났다. 이러한 결과는 정보 불평등을 해소하기 위해서 소외 계층이 정보화로 얻을 수 있는 만족과 기대 수준을 높이는 방향으로 정책이 추진되어야 하며 이를 위해서 소외 계층의 문화취향을 고려한 부처간 협력사업이 필요함을 시사한다.