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Choi, Dukhyun,Choi, Min-Yeol,Choi, Won Mook,Shin, Hyeon-Jin,Park, Hyun-Kyu,Seo, Ju-Seok,Park, Jongbong,Yoon, Seon-Mi,Chae, Seung Jin,Lee, Young Hee,Kim, Sang-Woo,Choi, Jae-Young,Lee, Sang Yoon,Kim, Jo WILEY-VCH Verlag 2010 ADVANCED MATERIALS Vol.22 No.19
<B>Graphic Abstract</B> <P>The cover shows an image of fully rollable transparent nanogenerators synthesized using chemical vapor deposition grown large-scale graphene sheets as transparent electrodes and piezoelectric ZnO nanorod arrays. Sang-Woo Kim, Jae-Young Choi, and co-workers report on p. 2187 the electrical and structural stability of the nanogenerators, with excellent charge scavenging performance under external mechanical loads such as bending and rolling. This study shows that graphene-based nanogenerators are very promising for self-powered rollable transparent device applications. <img src='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content.gif' alt='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content'> </P>
남세현,Chong-hai Lee1,Yu-wei Tang,Yuan-sheng Liu,Ki-chul Kim,Sang-yeol Chun,염유림,Hyung chang Kim,Myoung-deok Lee 대한한의학회 2015 대한한의학회지 Vol.36 No.4
The purpose of this report is to evaluate effect of Korean medical treatment on idiopathic gonadotropin-dependent precocious puberty (G-DPP) patient received herbal medicine. We administered Aesopjiyoun-tang remedy to idiopathic G-DPP and analyzed the delay effect by hormonal value and radiographs; the height growth effect by measurement of height. After Korean medical treatment, suppression effect to peak- Luteinizing Hormone level (LHL) is 14.39IU/L to 10.9IU/L for 13month, growth effect to height value is 11cm/13month; and change of mean growth velocity (MGV) is 6.08cm/year to 10.06cm/year. The gain in height by treatment is 3.98cm/year. The result suggests Aesopjiyoun-tang can be an effective treatment for G-DPP. Herbal medicine can be used as an alternative treatment in place of the GnRH treatment.
Lee, Seung Sik,Jung, Hyun Suk,Park, Soo-Kwon,Lee, Eun Mi,Singh, Sudhir,Lee, Yuno,Lee, Kyun Oh,Lee, Sang Yeol,Chung, Byung Yeoup MDPI 2015 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.16 No.11
<P>AtTDX, a thioredoxin-like plant-specific protein present in <I>Arabidospis</I> is a thermo-stable and multi-functional enzyme. This enzyme is known to act as a thioredoxin and as a molecular chaperone depending upon its oligomeric status. The present study examines the effects of γ-irradiation on the structural and functional changes of AtTDX. Holdase chaperone activity of AtTDX was increased and reached a maximum at 10 kGy of γ-irradiation and declined subsequently in a dose-dependent manner, together with no effect on foldase chaperone activity. However, thioredoxin activity decreased gradually with increasing irradiation. Electrophoresis and size exclusion chromatography analysis showed that AtTDX had a tendency to form high molecular weight (HMW) complexes after γ-irradiation and γ-ray-induced HMW complexes were tightly associated with a holdase chaperone activity. The hydrophobicity of AtTDX increased with an increase in irradiation dose till 20 kGy and thereafter decreased further. Analysis of the secondary structures of AtTDX using far UV-circular dichroism spectra revealed that the irradiation remarkably increased the exposure of β-sheets and random coils with a dramatic decrease in α-helices and turn elements in a dose-dependent manner. The data of the present study suggest that γ-irradiation may be a useful tool for increasing holdase chaperone activity without adversely affecting foldase chaperone activity of thioredoxin-like proteins.</P>
( Sung Soo Kim ),( Min Soo Kang ),( Kyu Yeol Lee ),( Myung Jin Lee ),( Lih Wang ),( Hyo Jong Kim ) 대한슬관절학회 2012 대한슬관절학회지 Vol.24 No.3
Purpose: To evaluate the treatment results of intraarticular injection according to the frequency of hyaluronic acid with mesenchymal stem cells on the osteochondral defect of rabbits` medial femoral condyles. Materials and Methods: A 5 mm diameter and 4 mm depth osteochondral defect was made on the medial femoral condyles of 18 rabbits, divided into six groups. One week after osteochondral defect, group B was injected intraarticularly with hyaluronic acid (HA), group C with mesenchymal stem cells (MSCs), and group D, E and F with both HA and MSCs. Group E and F received second HA injection a week after. Further, group F received third HA injection in the third week. Results: In a macroscopic evaluation, groups B (6; range, 5-8), C (6; range, 6-7), D (7; range, 6-7), E (6.5; range, 6-8) and F (7.5; range, 6-8) showed statistically significant improvements in osteochondral defect healing, compared with that of group A (4; range, 3-5) (p=0.002). In histological evaluation, groups B (11.5; range, 11-13), C (13; range, 12-18), D (16; range, 13-18), E (17.5; range, 13-20), and F (19.5; range, 12-22) showed statistically significant differences in osteochondral defect healing, compared with group A (8; range, 6-9) (p=0.006). Conclusions: The intraarticular injections of MSCs or HA can play an effective role during the healing osteochondral defects in rabbits.
Re-emergence of the Glossy Ibis (Plegadis falcinellus) in inland South Korea
Lee, Sang-Yeon,Sung, Ha-Cheol,Han, Donguk,Cha, Jin-Yeol The Ecological Society of Korea 2020 Journal of Ecology and Environment Vol.44 No.3
Glossy Ibis (Plegadis falcinellus), which has never been recorded in South Korea, appeared on Jeju Island in 2018 and re-emerged in the inland area of Seocheon-gun (South Chungcheong Province) and in Goyang-si (Gyeonggi Province) in the following year. This study aims to report the progress in observing P. falcinellus in the inland areas of South Korea in 2019 and to predict its origin region and future propensity for habitats in the country through literature review. On 5 May 2019, an individual of P. falcinellus with breeding feathers was observed in a farmland in Wolsan-ri, Seocheon-gun. Twelve days later, another one was identified in a farmland in Janghang-dong, Goyang-si, about 173 km north of Wolsan-ri. The observed birds fed and rested in the area and stayed for only a day. The individual birds spotted in South Korea in 2019 are conjectured to have come from either Southeast Asia or Australia, among areas located in East Asian-Australasian Flyway (EAAF). This is because P. falcinellus, a species with excellent dispersal capacity, forms a population in new areas during extreme environmental changes in their current habitats, especially droughts. For 2 years, P. falcinellus was observed to be migrating in spring; however, in the future, they may exhibit the same propensity for breeding and habitats as that of birds migrating in autumn. As it is a conspicuous species, effective detection of their arrival requires a survey system that classifies the country by habitat type and involves periodic and multiple observations by experts and citizens.
RESIDUAL EMPIRICAL PROCESS FOR DIFFUSION PROCESSES
Lee, Sang-Yeol,Wee, In-Suk Korean Mathematical Society 2008 대한수학회지 Vol.45 No.3
In this paper, we study the asymptotic behavior of the residual empirical process from diffusion processes. For this task, adopting the discrete sampling scheme as in Florens-Zmirou [9], we calculate the residuals and construct the residual empirical process. It is shown that the residual empirical process converges weakly to a Brownian bridge.
Lee, Sang A,Oh, Seokjae,Hwang, Jae-Yeol,Choi, Minseok,Youn, Chulmin,Kim, Ji Woong,Chang, Seo Hyoung,Woo, Sungmin,Bae, Jong-Seong,Park, Sungkyun,Kim, Young-Min,Lee, Suyoun,Choi, Taekjib,Kim, Sung Wng,C The Royal Society of Chemistry 2017 ENERGY AND ENVIRONMENTAL SCIENCE Vol.10 No.4
<P>Transition metal oxides have been extensively studied and utilized as efficient catalysts. However, the strongly correlated behavior which often results in intriguing emergent phenomena in these materials has been mostly overlooked in understanding the electrochemical activities. Here, we demonstrate a close correlation between the phase transitions and oxygen evolution reaction (OER) in strongly correlated SrRuO3. By systematically introducing Ru-O vacancies into the single-crystalline SrRuO3epitaxial thin films, we induced a phase transition in crystalline symmetry which resulted in the corresponding modification of the electronic structure. The modified electronic structure significantly affects the electrochemical activities, so a 30% decrease in the overpotential for the OER activity was achieved. Our study suggests that a substantial enhancement in the OER activity can be realized even within single material systems, by rational design and engineering of their crystal and electronic structures.</P>
Ultra-Specific Enrichment of GST-Tagged Protein by GSH-Modified Nanoparticles
Lee, Yeon-Ji,Park, Jong-Moon,Huh, Ji-Young,Kim, Min-Sik,Lee, Je-Sun,Palani, Arudra,Lee, Kwang-Yeol,Lee, Sang-Won Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.6
The selective isolation of specific proteins from complex protein mixtures by nanoparticles is reported. Glutathionemodified superparamagnetic nanoparticles were used to purify specific proteins fused with glutathione S-transferase via enzyme-substrate interactions. They demonstrated greatly improved selectivity and efficiency over micron sized capturing beads. The ultra-specific enrichment of target proteins was confirmed by both SDS-PAGE and LC/MS/MS experiments.