쥐의 實驗的 葡萄狀球菌性乳房炎에 關한 硏究

李政吉,康炳奎,李採瑢 全南大學校 農漁村開發硏究所 1980 農業科學技術硏究 Vol.15 No.-

The purpose of the present experiment is to determine the suitability of rat model for the experimental staphylococcal mastitis. A strain of Staphylococcus aureus isolated from a case of bovine mastitis was inoculated through the teat canal into the mammary gland of lactating rats. The rats were removed from their offspring or left with them to allow suckling, as required by the experimental design. 1. No generalized reactions or symptoms of mastitis were observed in all rats. 2. At necropsy, affected glands showed discoloration; abscesses up to 2.5mm in diameter were observed in one group of "lactating" rats inoculated with 10x10?? colony-forming units of staphylococcus. 3. Histologically fat droplets retained within the alveoli were prominent in many sections. Epithelial hyperplasia and slight interalveolar fibrosis were also noted. 4. The number of bacteria recovered from the inoculated mammary gland was smaller than that of bacteria inoculated. The bacteria were more readily recoverable from the mammary glands of "non-lactating" rats than from "lactating" rats. 5. To determine a suitable rat model for the experimental staphylococcal mastitis, further studies should be carried out, using different strains of Staphylococcus aureus and also different strains of rats.

Co-60 감마선에 대한 부정형조사면의 조직공중선량비(TAR) 계산

이수용,김채옥,김필수,지영훈 漢陽大學校 基礎科學硏究所 1988 基礎科學論文集 Vol.7 No.-

방사선치료에 사용되는 대표적인 부정형조사면 다섯가지에 대한 각 관심점에서의 선량계산을 위하여 새로 고안한 도표를 사용하여 Co-60감마선에 대한 부정형조사면의 조직공중선량비(TAR)를 계산하였다. 도표를 이용한 계산과 기존의 계산법인 컴퓨터계산법 및 근사법으로 구한 TAR를 측정에 의한 TAR에 비교하여 다음과 같은 결과를 얻었다. 관심점이 방사선속의 중심축상에 있을 때 부정형조사면에서 이들 방법으로 구한 TAR의 대부분은 오차가 1% 이내에서 잘 일치되어 있으며, 축으로부터 벗어난 경우에는 최대 오차가 각각 2.4%,2.3%, 및 8.8% 이었다. 이들 결과로부터 새로 고안한 도표를 이용한 계산법의 정확성을 확인하였다. In order to calculate the dose on each interest point in five types of irregularly shaped fields used commonly in radiotherapy, the tissue-air ratios (TAR) in these fields for Co-60 gamma radiation were calcnlated using the newly devised SAR-chart. The TARS calculated from newly method of using the SAR-chart. computer method and approximation method at the interest point were compared to the TARs obtained from measurement. The result are as follows: In case of the interest points on central axis the calculated TARs in irregularly shaped fields by the above metioned methods were well agreed within the error of 1%, whereas for the interest points on off-axis the calculated TARs were resulted in the maximum errors of 2.4%, 2.3% and 8.8% respectively. From these results, the accuracy of calculation method of using the SAR-chart was comfirmed.

페타이어의 재자원화 방안에 관한 연구

김용수,이주성,김영채,공성호,배성렬 한양대학교 에너지·환경기술연구소 1997 에너지·環境技術論文集 Vol.3 No.-

자동차 산업의 부산물로 발생되는 각종 폐고무류와 폐타이어 그리고 일반 제화공업이나 공산품의 제조공정에서 필연적으로 발생되는 합성 천연고무 폐기물은 국내에서만도 년간 16만톤이 발생되는 것으로 추정되고 있어 이로 인한 환경 및 사회적인 문제가 이미 심각한 상황에 도달해 있는 실정이다. 이러한 상황은 자동차 산업의 선진국인 미국의 경우에서 뿐만아니라 국토가 비좁은 구주의 경우도 폐타이어등 폐고무류에 의한 문제가 사회적으로 점차 심각하게 대두되고 있어 이의 처리에 대한 당위성은 이미 오래전부터 제기되어 왔다. 따라서 국내에서만도 년간 1200만개 이상 발생되는 폐타이어로 인한 환경문제를 해결하고 아울러 이를 에너지로 또는 유용한 자원으로 재환원하여 사용함으로써 국가에 크게 이바지할 수 있는 기술에 대한 실용화 연구는 꼭 필요하다.

회전익 항공기용 외활형식 착륙장치의 정ㆍ동적 분석에 관한 연구

유용석,이동명,채경덕,오택열 경희대학교 산학협력기술연구원 1996 산학협력기술연구논문집 Vol.2 No.-

It is important to make sure of design's reasonability concerning of structural vibration problems and safety with fulfilling the research and with analyzing the body structures that include the landing gear which has dynamic significant characteristics in helicopter, and to make systematical procedure which obtains engineering data to guarantee the quality of the helicopter that was developed by testing of parts, subsystems and body. In this study, Analysis of landing gear under FAR regulations was attempted, and systematical procedure for static and dynamic characteristics of the landing gear in many subsystems of the helicopter was classified.

약지반의 침하 예측에 관한 연구

장용채,이승은 木浦海洋大學校 2004 論文集 Vol.12 No.-

The controls for safe construction of road embankment on soft clays should be performed not to develope any distresses in the pavement structures. For this construction controls engineers measure consolidation settlements of the soft clays during and after placing embankment, analyze them, and then predict residual settlements. In this study, numerical analysis are performed for investigating each influence factor on central settlement. for example geological characteristics and material properties.

반월상 연골판 손상을 동반한 내측 측부인대 부분파열 환자의 한방 치료 효과: 증례보고

전용현(Yong-Hyun Jeon),김두리(Doo-Ri Kim),문희영(Hee-Young Moon),박지원(Ji-Won Park),이윤하(Yun-Ha Lee),채지원(Ji-Won Chai1),최동주(Dong-Joo Choi),최효정(Hyo-Jung Choi) 척추신경추나의학회 2019 척추신경추나의학회지 Vol.14 No.2

Objectives : The purpose of this report was to introduce 3 cases of patients diagnosed with both medial collateral ligament tear and meniscal tear that showed clinical improvement after Korean medicine treatment. Methods : These patients received Korean herbal medicine, pharmacopuncture treatment, and acupuncture treatment. We assessed these cases by using the Numeric Rating Scale (NRS), Western Ontario and McMaster Universities’Arthritis Index (WOMAC), and the European Quality of Life-5 Dimension Index (EQ-5D). Results : After Korean medicine treatment, most of the NRS, WOMAC, and EQ-5D scores showed improvement on every discharge date of these 3 cases. The NRS and WOMAC scores of all cases showed a decrease. The EQ-5D of all cases showed an increase. Conclusions : Through this research, we concluded that Korean medicine treatment can be helpful in relieving pain and improving the quality of life and function of knee joint movement in patients with medial collateral ligament tear and meniscal tears.

토목섬유를 이용한 대형직접전단시험에 관한 기초적인 연구

장용채,이승은 木浦海洋大學校 2005 論文集 Vol.13 No.-

Recently reinforced earth method using geosynthetics as a reinforcement has been getting popular and usefulness also has been increased due to reductions in costs and ease of construction and great exterior view. Geosynthetics are now being used as ground reinforcement materials all over the world, because we can make ground structures using geosynthetics economically and safely. The most important part in the earth reinforcement is the interface between soil and the reinforcement. Shear strength and shear behavior in this interface make a great role relating to the reinforcement effect. this paper presents 2 kinds of direct shear test results

산업피로의 자각증상에 관한 조사연구

김돈균,이채언,이상준,김용준 카톨릭대학산업의학센타 산업의학연구소 1976 韓國의 産業醫學 Vol.15 No.4

1975년 9월 1일부터 동년 12월 31일에 걸쳐 부산시내 8개 제조부문 20개 산업장 근로자 총 4,068명에 대한 산업피로 자각증상을 조사하여 얻은 바 성적을 요약하면 다음과 같다. 1. 전체 근로자들의 피로자각증상 호소율(이하 피로호소율로 약함)의 순서는 Ⅰ Dominant형을 보이고 있었다. 2, 업종별 피로자각증상 빈도(이하 피로빈도로 약함)는 섬유제품제조업이 가장 높았고 제1차 금속제품제조업에서 가장 낮았다. 업종별 피로호소율의 순서는 제1차 금속제품제조업과 기타제품제조업에서는 Ⅱ Dominant 형을 보이고 있었으나 그 외의 모든 업종은 I Dominant 형을 나타내고 있었다. 3. 연령별 피로빈도는 연령이 높아질수록 낮아지는 경향이 있었고 연령별 피로 호소율의 순서는 30-39세군만이 Ⅱ Dominant 형을 보였고 그 외의 모든 연령군에서는 Ⅰ Dominant 형을 나타내고 있었다. 4. 교육정도별 피로자각증상의 빈도는 무학군에서 가장 높았으며 그 피로호소율의 순서는 무학군에서는 Ⅲ Dominant 형을 보이고 있었으나 그 외의 모든 교육정도에 있어서는 공통적으로 Ⅰ Dominant 형을 보이고 있었다. 5. 근속연수별 피로빈도는 2년 이하의 근로자군에서 가장 높았고 10년이상에서 가장 낮았다. 근속연수별 피로호소율의 순서는 모두 Ⅰ Dominant 형을 보이고 있었다. 6. 수면시간별 피로빈도는 5시간군에서 가장 높았으며 8시간군에서 가장 낮았다. 수면시간별 피로호소율의 순서는 9시간군에서만 Ⅱ Dominant 형을 보였고 그 외의 군에서는 모두 I Dominant 형을 보이고 있었다. For the purpose of research on subjective symptoms of industrial fatigue, this study was conducted on 4,068 workers of 20 industries in 8 manufacturing fields in Busan City from september 1st to December 31st, 1975. The obtained result were as follows: 1. General type of subjective symptoms of industrial fatigue of total workers in various industries revealed Ⅰ Dominant type. 2. According to the frequency of subjective symptoms of industrial fatigue by industries, the highest was Textile and the lowest was Basic metal. And by the type of industrial fatigue, Basic metal and other manufacturing industries showed Ⅱ Dominant type but the others showed I Dominant type. 3. The frequency of industrial fatigue by the age group showed dereasing tendency with the higher age, and all groups showed I Dominant type except 30-39 years old group as Ⅱ Dominant type. 4. According to the frequency of industrial fatigue by educational level, the highest was in illiteracy group as Ⅲ Dominant type, but the others showed I Dominant type. 5. According to the frequency of industrial by the employed years, under 2 years group was the highest, the lowest was over 10 years group, and all groups showed Ⅰ Dominant type. 6. According to the frequency of industrial fatigue by the sleeping hours, the highest was 5 hours group and 8 hours group was the lowest. All group showed I Dominant type except 9 hours group as Ⅱ Dominant type.

산란계에 투여된 플루오로퀴놀론계 합성항균제의 계란내 이행 잔류 연구

서계원,이재일,이채용,김은선,이정치 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.4

In the past few years the use of four fluoroquinolones such as of ofloxacin(OF), norfloxacin(NORE), ciprofloxacin(CIP), enrofloxacin(ENR) in veterinary practice has increased. The aim of this study was to determine the elimination of fluoroquinolones into eggs, by intramuscular injection of laying hens(2.5mg of ENR/kg, 5mg of CIP/kg, 5mg of NOR/kg, 5mg of OF/kg). The treatment of fluoroquinolones was carried out in 3 stages with 9 laying hens (Isabrown), with mean weight 1.8kg, which were housed in individual cages. Four fluoroquinolones were administered to 9 laying hens through intramuscular injection at 1 day, 2 days, 5 days trial respectively. Sample (Albumen, Yolk, Whole egg) were analysed by high performance liquid chromatography (HPLC) with a fluorescence programmable detector and matrix solid phase despersion (MSPD) extraction. Residues of fluoroquinolones were much higher in the yolk than in the albumen. Detectable residues persisted for 12 days, 14 days, 16 days, respectively, in albumen and yolk after the injection was discontinued. The increase of the fluoroquinolones concentration in yolk was very rapid and reached a plateau after 3 days of dosing. In albumen, the fluoroquinolones concentration increased during intramuscular injection. As soon as the injection was discontinued, residues decreased in the albumen and the yolk.

MSPD법과 HPLC를 이용한 계란내 플루오로퀴놀론계 항균물질의 동시 다성분 정량분석

서계원,이재일,이채용,김은선,이정치 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.4

A multi-residue matrix solid-phase dispersion extraction and the liquid chromatographic determination of enrofloxacin, ciprofloxacin, norfloxacin and ofloxacin in eggs is described. Blank and fluoroquinolones fortified egg samples (0.5 g) containing oxalic acid 0.05 g and sodium sulfate (anhydrose) 0.5 g were blended with octadecylsilyl (C_(18), 40 m, 18% load, endcapped, 2 g) derived from silica. After homogenization, C_(18)/egg matrix was transferred to column made of 10 ml plastic syringe and filter paper, and compressed 4.0 4.5 ml volume. A column was washed with 8 ml of hexane followed by 8 ml of ethylacetate and dried under N2 gas. Fluoroquinolones were eluated with 8 ml of methanol under gravity. The eluate contained fluoroquinolones, was free from interferences when analyzed by high performance liquid chromatography with fluorescence detection. Correlation coefficients for the fluoroquinolones standard curves (linear regression analysis, n = 5) ranged from 0.99918 (± 0.0035) to 0.99985 (± 0.0002). Aveage recoveries of fortified samples were between 89.4 and 103.5%. The method comparared favorably with the classical method in terms of the sample size, analysis time and overalls costs.