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      • Cholestyramine과 Polyvinylpyrrolidone에 대한 Bilirubin 흡착의 Photoenhancement에 관한 연구

        신대현,St-pierre, L.E.,조인호 全北大學校 基礎科學硏究所 1983 基礎科學 Vol.6 No.1

        Totally internal hydrogen bonded ZZ form of bilirubin can be converted under photoirradiation with blue filtered light to three forms : EZ,ZE and EE, all of which give greater accessibility to the polar functional groups. Accordingly, I have attrmped to discern whether the photolized-bilirubin could be adsorbed more rapidly on the two adsorbents than do the ZZ form, particularly on CA which has slower equilibrium, but greater adsorption capacity. The rate of adsorption of photolized-bilirubin on CA is seen to be considerably faster than that of the ZZ form. Thus the adsorption equilibrum could be improved by pre-irradiation of aqueous billrubin solution. It will be determined if this phenomenon may aid the phototherapy tretment of hyperbilirubinaemia cases.

      • KCI등재

        Tribology in Linear Electric Motor with Plate Mover

        Kenfack Pierre,Dandoussou Abraham,Perabi Stève Ngoffe,Kana’a Thomas 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.5

        This paper deals with tribological systems of a linear electric motor for high-frequency motion and high acceleration, intended for the creation of an acoustic wave of the thermoacoustic conversion system. The main originality of this structure resides in the linear guidance (based on pressure screws acting on springs) used for the plate mover. Given the high acceleration and speed, it was impossible to use traditional mechanical guidance processes (V-guide rail and Cam-roller guide). The plate mover is made up of a translator of sandwiched magnets between two stationary stators. This plate mover is in magnetic balance between the two stationary stators through a controlled friction device.

      • KCI등재

        Enhancement of Mass Transfer Characteristics and Phenanthrene Degradation in a Two-phase Partitioning Bioreactor Equipped with Internal Static Mixers

        Abdelhay Arwa,Stéphane Baup,Nicolas Gondrexon,Jean-Pierre Magnin,John Willison 한국생물공학회 2011 Biotechnology and Bioprocess Engineering Vol.16 No.2

        Oxygen and substrate supply have always been considered physical constraints for the performance and operation of two-phase partitioning bioreactors (TPPB),widely used for the degradation of hydrophobic substrates. In this regard, the potential advantages of static mixers in upgrading the oxygen transfer and liquid-liquid dispersions in TPPB have been highlighted. In the present paper, the concomitant influence of static mixers on the gas-liquid mass transfer coefficient kLa and on substrate bioavailability was examined in TPPB. The static method based on conventional forms was developed to estimate the oxygen volumetric mass transfer coefficient. Over a broad range of liquid and air flow rates, the presence of static mixers was found to significantly enhance kLa relative to a mixer-free mode of operation. For identical conditions, static mixers improved the kLa threefold. In the presence of external aeration supply, the boost in the kLa was associated with an increase of 16% in the phenanthrene biodegradation rate due to bubble break up accomplished by the static mixers. On the other hand, static mixers were efficient in enhancing substrate bioavailability by improving the liquid-liquid interfacial area. This effect was reflected by a threefold increase in the degradation rate in the bioreactors with no external supply of air when equipped with static mixers.

      • KCI등재

        The Kernohan-Woltman Notch Phenomenon : A Systematic Review of Clinical and Radiologic Presentation, Surgical Management, and Functional Prognosis

        Nathan Beucler,Pierre-Julien Cungi,Guillaume Baucher,Stéphanie Coze,Arnaud Dagain,Pierre-Hugues Roche 대한신경외과학회 2022 Journal of Korean neurosurgical society Vol.65 No.5

        The Kernohan-Woltman notch phenomenon (KWNP) refers to an intracranial lesion causing massive side-to-side mass effect which leads to compression of the contralateral cerebral peduncle against the free edge of the cerebellar tentorium. Diagnosis is based on “paradoxical” motor deficit ipsilateral to the lesion associated with radiologic evidence of damage to the contralateral cerebral peduncle. To date, there is scarce evidence regarding KWNP associated neuroimaging patterns and motor function prognostic factors. A systematic review was conducted on Medline database from inception to July 2021 looking for English-language articles concerning KWNP, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The research yielded 45 articles for a total of 51 patients. The mean age was 40.7 years-old and the male/female sex ratio was 2/1. 63% of the patients (32/51) suffered from head trauma with a majority of acute subdural hematomas (57%, 29/51). 57% (29/51) of the patients were in the coma upon admission and 47% (24/51) presented pupil anomalies. KWNP presented the neuroimaging features of compression ischemic stroke located in the contralateral cerebral peduncle, with edema in the surrounding structures and sometimes compression stroke of the cerebral arteries passing nearby. 45% of the patients (23/51) presented a good motor functional outcome; nevertheless, no predisposing factor was identified. A Glasgow coma scale (GCS) of more than 3 showed a trend (p=0.1065) toward a better motor functional outcome. The KWNP is a regional compression syndrome oftentimes caused by sudden and massive uncal herniation and leading to contralateral cerebral peduncle ischemia. Even though patients suffering from KWNP usually present a good overall recovery, patients with a GCS of 3 may present a worse motor functional outcome. In order to better understand this syndrome, future studies will have to focus on more personalized criteria such as individual variation of tentorial notch width.

      • KCI등재

        NURBS-based surface generation from 3D images: spectral construction and data-driven model selection

        Perney Antoine,Bordas Stéphane,Kerfriden Pierre 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.4

        In this paper, we present a set of improved algorithms for recovering computer aided design (CAD-type) surface models from three-dimensional (3D) images. The goal of the proposed framework is to generate B-spline or non-uniform rational B-spline (NURBS) surfaces, which are standard mathematical representations of solid objects in digital engineering. To create a NURBS surface, we first compute a control network (a quadrilateral mesh) from a triangular mesh using the Marching Cubes algorithm and Discrete Morse theory. To create a NURBS surface, we first compute a triangular mesh using the Marching Cubes algorithm, then the control network (a quadrilateral mesh) is determined from the triangular mesh by using Discrete Morse theory. Discrete Morse theory uses the critical points of a specific scalar field defined over the triangulation to generate a quad mesh. Such a scalar field is obtained by solving a graph Laplacian eigenproblem over the triangulation. However, the resulting surface is not optimal. We therefore introduce an optimization algorithm to better approximate the geometry of the object. In addition, we propose a statistical method for selecting the most appropriate eigenfunction of the graph Laplacian to generate a control network that is neither too coarse nor too fine, given the precision of the 3D image. To do this, we set up a regression model and use an information criterion to choose the best surface. Finally, we extend our approach by taking into account both model and data uncertainty using probabilistic regression and sampling the posterior distribution with Hamiltonian Markov Chain Monte Carlo.

      • KCI등재

        Experimental and numerical study of a modified ASTM C633 adhesion test for strongly-bonded coatings

        Raphaëlle Bernardie,Reda Berkouch,Stéphane Valette,Joseph Absi,Pierre Lefort 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.7

        When coatings are strongly bonded to their substrates it is often difficult to measure the adhesion values. The proposed method, which is suggested naming “silver print test”, consists in covering the central part of the samples with a thin layer of silver paint, before coating. The process used for testing this new method was the Air plasma spraying (APS), and the materials used were alumina coatings on C35 steel substrates, previously pre-oxidized in CO 2 . The silver painted area was composed of small grains that did not oxidize but that significantly sintered during the APS process. The silver layer reduced the surface where the coating was linked to the substrate, which allowed its debonding, using the classical adhesion test ASTM C633-13, while the direct use of this test (without silver painting) led to ruptures inside the glue used in this test. The numerical modelling, based on the finite element method with the ABAQUS software, provided results in good agreement with the experimental measurements. This concordance validated the used method and allowed accessing to the values of adherence when the experimental test ASTM C633-13 failed, because of ruptures in the glue. After standardization, the “silver print test” might be used for other kinds of deposition methods, such as PVD, CVD, PECVD.

      • KCI등재

        Glenohumeral joint capsular tissue tension loading correlates moderately with shear wave elastography: a cadaveric investigation

        Charles W. Nichols,Jean-Michel Brismée,Troy L. Hooper,Antony Bertrand-Grenie,Kerry K. Gilbert,Marc-Olivier St-Pierre,Jeegisha Kapila,Stéphane Sobczak 대한초음파의학회 2020 ULTRASONOGRAPHY Vol.39 No.2

        Purpose: The purpose of this study was to investigate changes in the mechanical properties of capsular tissue using shear wave elastography (SWE) and a durometer under various tensile loads, and to explore the reliability and correlation of SWE and durometer measurements to evaluate whether SWE technology could be used to assess tissue changes during capsule tensile loading. Methods: The inferior glenohumeral joint capsule was harvested from 10 fresh human cadaveric specimens. Tensile loading was applied to the capsular tissue using 1-, 3-, 5-, and 8-kg weights. Blinded investigators measured tissue stiffness and hardness during loading using SWE and a durometer, respectively. Intraobserver reliability was established for SWE and durometer measurements using intraclass correlation coefficients (ICCs). The Pearson product-moment correlation was used to assess the associations between SWE and durometer measurements. Results: The ICC3,5 for durometer measurements was 0.90 (95% confidence interval [CI], 0.79 to 0.96; P<0.001) and 0.95 (95% CI, 0.88 to 0.98; P<0.001) for SWE measurements. The Pearson correlation coefficient values for 1-, 3-, and 5-kg weights were 0.56 (P=0.095), 0.36 (P=0.313), and -0.56 (P=0.089), respectively. When the 1- and 3-kg weights were combined, the ICC3,5 was 0.72 (P<0.001), and it was 0.62 (P<0.001) when the 1-, 3-, and 5-kg weights were combined. The 8-kg measurements were severely limited due to SWE measurement saturation of the tissue samples. Conclusion: This study suggests that SWE is reliable for measuring capsular tissue stiffness changes in vitro at lower loads (1 and 3 kg) and provides a baseline for the non-invasive evaluation of effects of joint loading and mobilization on capsular tissues in vivo.

      • Biominerization of Iron : Mo¨ssbauer spectroscopy and Electron Microscopy of Ferrtin Cores from theChiton Acanthopleura hirtosa and the Limpet patella laticostata. Mo¨ssbauer spectroscopy와 전자 현미경을 이용한 Ferritin Core의 연구

        Pierre, T.G.,Kim, K.S.st.,Webb, J.,Mann, S.,Dickson, D.P.E. 全北大學校 基礎科學硏究所 1991 基礎科學 Vol.14 No.2

        Ferritins isolated from the hemolymph of the chiton Acanthopleura hirtosa and the limpet Patella laticostata have been studied by ^57Fe Mossbauer spectroscopy, electron diffraction, transmission electron microscopy (TEM), and inductively coupled plasma(ICP) spectrometry. Mossbauer spectra of the samples at 78 K were quadrupole-split doublets with similar quadrupole splittings and chemical isomer shifts, characteristic of octahedral high-spin iron(III), while at 4.2K the spectra were magnetically split sextests. The spectra yield mean superparamagnetic blocking temperatures of about 32 and 30 K for the A. hirtosa and P. laticostata ferritins, respectively, and indicate magnetic ordering temperatures of about 37 and 34 K. Core size distributions were measured for both the A. hirtosa and P. laticostata ferritins by using TEM and gave mean core size ranges of 8.0-8.5 and 7.5-8.0 nm, respectively. Diffuse lines in the electron diffraction patterns of the ferritin cores indicated the presence of ferrihydrite(5Fe_2-O_3·9H_2O) of limited crystallinity. Phosphorus to iron atomic ratios were measured by ICP spectrometry. The phosphorus levels were close to the limit of detection, giving approximate mean values of D:Fe of 1:44 for the P. laticostata ferritin and 1:36 for the A. hirtosa ferritin. These levels of phosphate are significantly less than those for the crystalline cores of mammalian ferritins and considerably less than those for the noncrystalline core of bacterioferritins.

      • The Role of Metaphor in Sport Instruction

        Peter E. St. Pierre,Mark A. Smith 한국코칭능력개발원 2012 International Journal of Coaching Science Vol.- No.-

        Teachers and sport instructors have embraced the use of metaphors as a tool that enhances student performance, but there is little research explaining the reasons why they are used. The purpose of this study was to examine metaphor use by expert golf instructors. Fourteen individuals selected as Top 100 instructors by Golf Magazine in 2000 or 2001 participated in the study. Each instructor recruited a student and was videotaped teaching a lesson. Following the lesson, the student and instructor participated separately in stimulated recall interviews. Results from this study suggest that metaphor use is pervasive in expert golf instruction, and is an important teaching tool for most instructors. The use of metaphors resulted in immediate changes in behavior, and memorable learning. When metaphors were used by these instructors, the students understood them as intended more than ninety percent of the time, and showed observable changes in performance during practice. The findings also provide some empirical evidence supporting Andrew Ortony’s (1975) three theses regarding the role of metaphor in language. Instructors used metaphors to encourage vivid mental images, to make language more efficient, and to express concepts that would be difficult to explain through literal language.

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