Novel approaches to nano-material analysis using TOF-MEIS

Kyungsu PARK,Won Ja MIN,Jwa-Soon KIM,Kwang Hwan JUNG,Sung Yup AN,Seung Gyun KIM,Chang Sik SIM,Soobang KIM,Wan Sup KIM,Kyu-Sang YU 한국진공학회 2016 한국진공학회 학술발표회초록집 Vol.2016 No.8

경운기의 사용 실태와 안전 및 대체 농기계 관련 인식 : 연령별 비교를 중심으로

김경수(Kyungsu Kim),최동필(Dongphil Choi),최원종(Wonjong Choi),김효철(Hyocher Kim),김인수(Insoo Kim),이현경(Hyeongyeong Lee) 한국지역사회생활과학회 2020 한국지역사회생활과학회지 Vol.31 No.4

이산 코사인 변환을 이용한 형태 특징 추출 기법

김경수(Kim Kyungsu),이영신(Lee Yungsin),김용국(Kim Yongkuk),이윤배(Lee Yunbae),김판구(Kim Panku) 한국정보처리학회 1998 정보처리학회논문지 Vol.5 No.5

In this paper, we propose the method that extract shape features using the DCT(Discrete Cosine Transform) via simple invariant normalization. To retrieve effectively, we used measures, circularity and eccentricity, as filters to reduce the number of retrieved images. The experimental results show that our method is better than the methods of Fourier Descriptors and Moment Invariant for various leaf images.

국내외 농업인 천식 및 만성 폐쇄성 폐질환에 관한 고찰

김시영(Siyoung Kim),윤성용(Seongyong Yoon),김진석(Jinseok Kim),조성용(Seong-yong Cho),박현우(Hyun Woo Park),김대환(Daehwan Kim),김가영(Gayoung Kim),강지수(Jisoo Kang),김경수(Kyungsu Kim),최동필(Dongphil Choi),유석주(Seok-Ju Yoo) 한국농촌의학 지역보건학회 2023 농촌의학·지역보건 Vol.48 No.4

본 연구는 국내 농업인의 천식 및 만성 폐쇄성 폐질환을 파악하기 위해「농업인의 업무상 질병 및 손상조사」를 조사하였다. 관련된 국내연구 자료가 미비하여 국외 농업인의 천식 및 만성폐쇄성 폐질환 연구결과를 찾아보았고, 그 결과. 국내 농업인들의 천식 및 만성 폐쇄성 폐질환 유병률은 국외 연구 결과들보다 낮게 나타났다. 실제 국내 농업인의 호흡기 질환 유병률은 더 높을 수 있으므로, 추가적인 연구가 필요하고, 호흡기 질환 예방대책이 마련되어야 한다. Objective: Farmers are known to have high prevalence of asthma and chronic obstructive pulmonary disease(COPD). This study aims to investigate the current status of asthma and COPD in domestic and foreign farmers with the ultimate goal of raising awareness of asthma and COPD among farmers and contribute to supporting evidence for the prevention of respiratory diseases in farmers. Methods: The study utilized data from the Farmer’s Occupational Disease Survey, conducted by the Rural Development Administration, to determine the prevalence of respiratory diseases in domestic farmers. The prevalence of asthma and COPD in overseas farmers was evaluated by researching other foreign studies and articles. Results: The prevalence of asthma and COPD in domestic farmers was less than of foreign farmers’. The prevalence of asthma in domestic farmers was high as upto 8.4% and COPD upto 5.5%. Studies from Europe and America showed prevalence of asthma in farmers high as upto 14.8% and COPD upto 17.1%. Conclusions: This study conducted an investigation using the Survey on Occupational Diseases and Injuries in Farmers to understand the current status of asthma and COPD in domestic farmers. Due to a lack of relevant domestic research, we examined and compared with the research results on asthma and COPD among overseas farmers. Further research is necessary and preventive measures for respiratory diseases need to be developed.

농업인의 안전활동을 위한 ICT 기반의 농업시설 안전관리 시스템에 관한 연구

김인수(Insoo Kim),김경란(Kyungran Kim),김효철(Hyo-Cher Kim),서민태(Min-Tae Seo),김경수(Kyungsu Kim),고명선(Myungsun Ko) 대한인간공학회 2018 大韓人間工學會誌 Vol.37 No.4

Objective: This study proposed a system for safe management of agricultural facilities whereby safety accidents of farmers are prevented from harmful factors of agricultural facilities and relevant hazardous situations, and efficient reaction is made possible when an accident occurs. Background: Recent development of information and communication technology (ICT) brought groundbreaking development of cutting-edge technologies such as the internet of things (IoT) and ubiquitous sensor network, and application of such technologies is expanding to the area of industrial safety. In particular, accidents from the hazardous environment surrounding agricultural facilities, say, from harmful gases, are frequently taking place and therefore development of services for safe farming work is required. Method: This study examined the types of safety accidents related to agricultural facilities occurring during farming work and designed a ICT-based system for safe management of accidents. Results: This study presents a model of such system and the model has the following functions: detection of harmful environment and conditions dangerous to farmers with sensor technologies; communication network technology for prevention of and fast coping with accidents; and user interface aimed at monitoring harmful environment and dangerous situations. Conclusion: The ICT-based system for safe management of agricultural facilities proposed in this study is expected to be applied as an application technology for safe agricultural activities. Application: The outcome of this study will be useful to develop a convergent ICTbased system for the prevention of safety accidents related to agricultural facilities.

비닐하우스 작업자의 서열 스트레스 경감을 위한 보텍스 튜브 적용 냉각조끼 개발 및 평가

김인수(Insoo Kim),김경란(Kyungran Kim),서민태(Min-Tae Seo),박수인(Soo-In Park),차종진(Joung-Jin Cha),김효철(Hyo-Cher Kim),김경수(Kyungsu Kim) 대한인간공학회 2020 大韓人間工學會誌 Vol.39 No.1

Objective: This study developed working clothes using a vortex tube device to reduce the thermal stress of greenhouse workers, and evaluated the physiological effects and user satisfaction of the developed cooling vest. Background: During the summer, the inside of greenhouses causes increased physiological burden of workers due to a high temperature and humidity, causing accidents and lowering the work efficiency. As a measure to solve this problem, various working clothes to lower thermal stress have been researched and developed, but there were limitations in the development of working clothes appropriate for high temperature and humidity in greenhouses. Therefore, the development of a new agricultural working clothes is required to prevent thermal stress of workers in a warm environment. Method: To verify the thermal stress reduction effect of the farming vest applying a vortex tube device, a physiological evaluation test was performed for subjects in a climate chamber and greenhouse environment. In addition, the wearing satisfaction and field applicability of the developed working clothes was evaluated by farmers. Results: The results of analyzing the mean physiological reactions by body part in the climate chamber test, the skin temperature, mean temperature in the working clothes, mean humidity, and heartrate of the developed working clothes decreased by 2.9%, 8.1%, 35.5%, and 4.9%, respectively, compared to the existing working clothes. Furthermore, in the greenhouse environment test, the temperature in the working clothes and humidity of the developed working clothes decreased by 8.8% and 12.3%, respectively, compared to the existing working clothes. Furthermore, in wearing sense and user satisfaction survey for farmers in the field evaluation, the respondents showed positive responses. Conclusion: This study verified the effects of the agricultural working clothes applying the vortex tube technology had an effect of thermal stress reduction compared to the existing working clothes and its applicability to the agricultural work environment. Further practical research should be conducted considering the cultivation environment and the size of greenhouse facilities to develop working clothes for various work environments. Application: The results of this study are expected to be utilizable in the field of design of thermal stress reducing working clothes for greenhouse facility farm workers.

농업분야에 적용이 가능한 산업용 ICT 융합 개인보호 및 편이장비 특허동향 분석

김인수(Insoo Kim),김경수(Kyungsu Kim),채혜선(Hye-Seon Chae),김효철(Hyo-Cher Kim),김경란(Kyung-Ran Kim) 한국지역사회생활과학회 2017 한국지역사회생활과학회지 Vol.28 No.3

An Antibody Designed to Improve Adoptive NK-Cell Therapy Inhibits Pancreatic Cancer Progression in a Murine Model

Lee, Jaemin,Kang, Tae Heung,Yoo, Wonbeak,Choi, Hyunji,Jo, Seongyea,Kong, Kyungsu,Lee, Sang-Rae,Kim, Sun-Uk,Kim, Ji-Su,Cho, Duck,Kim, Janghwan,Kim, Jeong-Yoon,Kwon, Eun-Soo,Kim, Seokho AMERICAN ASSOCIATION FOR CANCER RESEARCH 2019 CANCER IMMUNOLOGY RESEARCH Vol.7 No.2

<P>The homing of natural killer (NK) cells is often inhibited by pancreatic cancer tumors. A mesothelin-directed antibody conjugated to a cleavable NK cell—recruiting chemokine increased NK-cell infiltration of PDAC tumors, reduced tumor burden, and improved survival.</P><P>Natural killer (NK) cells are primary immune cells that target cancer cells and can be used as a therapeutic agent against pancreatic cancer. Despite the usefulness of NK cells, NK-cell therapy is limited by tumor cell inhibition of NK-cell homing to tumor sites, thereby preventing a sustained antitumor immune response. One approach to successful cancer immunotherapy is to increase trafficking of NK cells to tumor tissues. Here, we developed an antibody-based NK-cell–homing protein, named NK-cell–recruiting protein-conjugated antibody (NRP-body). The effect of NRP-body on infiltration of NK cells into primary and metastatic pancreatic cancer was evaluated <I>in vitro</I> and in murine pancreatic ductal adenocarcinoma models. The NRP-body increased NK-cell infiltration of tumors along a CXCL16 gradient (CXCL16 is cleaved from the NRP-body by furin expressed on the surface of pancreatic cancer cells). CXCL16 induced NK-cell infiltration by activating RhoA via the ERK signaling cascade. Administration of the NRP-body to pancreatic cancer model mice increased tumor tissue infiltration of transferred NK cells and reduced the tumor burden compared with that in controls. Overall survival of NRP-body–treated mice (even the metastasis models) was higher than that of mice receiving NK cells alone. In conclusion, increasing NK-cell infiltration into tumor tissues improved response to this cancer immunotherapy. The combination of an NRP-body with NK-cell therapy might be useful for treating pancreatic cancer.</P>

A Discussion on the Deep Horizontal Drillhole Disposal Concept of Spent Nuclear Fuel in Korea

Kyungsu Kim,Sung-Hoon Ji 한국방사성폐기물학회 2019 방사성폐기물학회지 Vol.17 No.3

본 논문에서는 최근 새롭게 제안된 심부수평시추공처분 개념을 소개하고, 우리나라 여건에서는 어떻게 적용될 수 있을지에 대하여 고려해 보았다. 이 개념은 방향제어시추기술로 심부수평시추공을 설치하고 고준위방사성폐기물을 처분하는 개념으로, 경제성과 안전성에서 기존의 동굴식 처분개념에 비해 큰 장점을 가지고 있는 것으로 평가된다. 그러나, 아직까지 아이디어 수준이므로 국제사회에서 처분 안전성과 성능을 실증하기까지 시간이 꽤 걸릴 것이고, 규제기관의 지침 개발도 뒷받침되어야 하는 문제가 있다. 우리나라는 국토가 좁고 인구밀도가 높아 NIMBY (Not In My Back Yard) 현상이 강할 수 밖에 없고, 더불어 사용후핵연료 발생량도 적지 않아 매우 어려운 입지여건을 가지고 있다. 이러한 여건에서 연안 육지부보다는 대륙붕의 안정된 환경의 장점을 살려 연안 해저암반을 심부수평시추공처분 개념의 처분영역으로 활용한다면 해당 지역사회의 심리적인 불안감을 획기적으로 완화시킬 수 있고 처분 안전성도 향상시킬 수 있을 것으로 기대한다. 더불어, 중앙집중식심부 동굴처분시설을 건설하는 경우에도 대륙붕을 활용하여 동일한 장점을 살리는 것을 고려해볼 필요가 있다. This technical note introduces a newly-proposed concept of deep horizontal drillhole disposal of spent nuclear fuel, and considers how it can be applied in the Korean environment. This disposal concept, in which high-level radioactive waste is disposed in deep horizontal drillholes installed with directional drilling technique, is expected to have great advantages over the existing deep mined repository concept in economics and safety. Since this concept is still at the idea level, however, it is necessary for worldwide expert groups to demonstrate its safety and performance. In addition, the development of guidelines by the regulatory body should be supported. The Korean circumstances, which include a narrow territory and a high population density, as well as the amount of spent nuclear fuel, make the NIMBY (Not In My Back Yard) phenomenon very strong and the siting conditions difficult. Under these conditions, if the disposal section of deep horizontal drillhole concept can be located at the continental shelf, with a stable environment, rather than in a coastal land area, it is expected to alleviate the psychological anxiety of the local community and stakeholders. Moreover, even when constructing a centralized deep mined repository in the future, it is necessary to consider locating the repository in the continental shelf.

Isolation of phlorotannins from Eisenia bicyclis and their hepatoprotective effect against oxidative stress induced by tert-butyl hyperoxide.

Kim, Sang Min,Kang, Kyungsu,Jeon, Je-Seung,Jho, Eun Hye,Kim, Chul Young,Nho, Chu Won,Um, Byung-Hun Humana Press 2011 Applied biochemistry and biotechnology Vol.165 No.5

<P>Eisenia bicyclis (Kjellman) Setchell is a common brown alga that inhabits the middle Pacific coast around Korea and Japan. In this study, the ethanol extract and its serial solvent fractions were prepared from fresh E. bicyclis, and their hepatoprotective effects were investigated against hepatotoxicity in tert-butyl hyperoxide(t-BHP)-injured HepG2 cells. When these samples were used at a dose of 10-40 μg/mL?1, they significantly protected the t-BHP-induced cell death in HepG2 cells. Among fractions, ethyl acetate fraction (EF) and n-butanol extract (BF) exhibited potent hepatoprotective activities (62.60% for EF and 64.86% for BF) in t-BHP-injured HepG2 cells at a concentration of 10 μg/mL?1. To find the potential factors for this activity, the samples were characterized on total phenolics, chlorophylls, carotenoids, and radical scavenging activity. Among them, EF showed the highest content of total phenolics and the strongest antioxidant activity both in on- and offline assays. Five phlorotannin compounds, oligomers of phloroglucinol, were isolated chromatographically from this fraction and structurally identified by (1)H-NMR and liquid chromatography-electrospray ionization-mass spectrometry analyses as eckol(1), 6,6'-bieckol(2), 8,8'-bieckol(3), dieckol(4), and phlorofucofuroeckol A(5). Compound 5 among five purified compounds showed the strongest protective activity (45.54%) at a concentration of 10 μM. At the high dose (40 μM), the protective activities of three compounds (compound 2, 4, and 5) were higher than that of quercetin treated with 10 μM concentration. Therefore, we can speculate that they can be developed as potential candidates for natural hepatoprotective agents.</P>