HPLC/FLD를 이용한 성별·연령별 혈장 homocysteine 정상치 조사

이경옥,류광석,이규범,이경옥,류광석,이규범 대한임상검사정도관리학회 1999 臨床檢査와 精度管理 Vol.21 No.1

정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여

신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.

화학적 요부 교감신경절 차단에서 한 분절 차단과 두 분절 차단의 비교

김종일,이규종,이상곤,민병우,반종석,문철준 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4

Chemical Lumbar Sympathetic Block: Comparison of One- Versus Two-needle Techniques Chul-Jun Mun, M.D., Kyu-Jong Lee, M.D., Sang-Gon Lee, M.D., Jong-Il Kim, M.D.^* Jong-Suk Ban, M.D., and Byung-Woo Min, M.D. Department of Anesthesiology, Fatima Hospital, Daegu, Korea ^*Kim Jong Il Pain Clinic, Daegu, Korea Background: It was frequently noticed in the course of performing a two-needle sympathectomy, that satisfactory spread of contrast solution could be produced by injection through only one of the needles. This led to a closer examination of the merits of single-needle technique. Methods: Forty patients were randomized into two groups. Patients in the single-needle group (n = 20) were injected at the second or third lumbar sympathetic ganglia, while patients in the two-needle group (n = 20) were injected at the second and thired lumbar sympathetic ganglia. Lumbar sympathetic blocks were performed using 3 ml of alcohol and the spread of injectate was verified with C-arm fluoroscopy. The indicators of a successful sympathetic block are increasing skin temperature, decreasing pain, and anhidrosis in the distal extremity. Results: The duration of anhidrosis was 12.2 ?? 2.6 months (mean ?? SD) in the single-needle group versus 13.6 ?? 3.6 months (mean << SD) in the two-needle group. Conclusions: As these results were not significantly different from those obtained in patients having considered to be effective for a neurolytic ;i,bar sympathectomy. (korean J Anesthesiol 2001; 41: 439~443)

상악 정중부에 역위 매복된 과잉치의 악골 내 이동

이석우,이제호,김성오,최형준,손홍규,최병재 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

과잉치는 상악 정중부에서 주로 발견되며,과잉치의 발생 기전은 유전적 또는 환경적 원인에 의하여 치배 형성기 동안에 정상 치판의 비정상적 증식에 의한 것으로 보고되었다. 과잉치로 인한 합병증으로는 인접 영구치의 맹출 장애와 전위,회전,정중이개,비강으로의 맹출,낭종 형성 등 이 있다. 과잉치를 외과적으로 발거하기 위한 시기에 대해서는 논란이 되고 있다. 인접치의 배열과 맹출 장애,전위를 야기할 수 있기 때문에 조기에 발거하자는 견해와 어린이의 행동 조절 및 인접 영구치의 치근 형성 정도를 고려하여 8~l0세 이후에 발거 하자는 견해가 있다. 후자와 같이 외과적 발거 시기를 연기할 경우,역위 및 수평 매복된 과잉치는 악골 내에서 비강 또는 경구개,소구치 부위 등으로 이동할 수 있으며,과잉치의 이동과 전상악골의 수직고경 증가로 인하여 외과적 발거 시 난이도가 높아질 수 있다. 따라서,역위 및 수평 매복된 과잉치의 외과적 발거 시기를 결정하기 위하여 연기하는 경우에 과잉치의 악골 내 이동을고려해야한다. 이 증례는 상악 정중부에 역위 매복된 과잉치가 있어서 내원한 6~7세의 어린이에서 과잉치의 외과적 발거 시기를 결정하기 위하여 주기적인 방사선 학적 검사로 관찰하던 중에 2~3년 후 과잉치 위치가 악골 내에서 초진 시 위치로부터 이동된 경우로 이를 보고하는 바이다. Supernumerary teeth are frequently found in the anterior portion of the maxilla and develop as a result of abnormal proliferation of the dental lamina during tooth germ formation, caused by genetic or environmental factors. They may result in various complications, such as eruption interference, displacement, rotation of adjacent teeth, diastema, eruption into the nasal cavity, and development of dentigerous cyst. The optimal time for surgical extraction of supernumerary teeth has been a controversial issue. Someone prefer early surgical extraction because supernumerary teeth can cause eruption interference and displacement of adjacent teeth, eventually altering occlusion. Others prefer to delay surgical extraction until 8~10 years of age in consideration of root maturation of the adjacent teeth and also patient's behavior. When surgical extraction of supernumerary teeth is postponed, there is possibility that impacted supernumerary teeth in the inverted or horizontal position move toward the nasal cavity, hard palate, or premolar area. When such intraosseous tooth migration is combined with the vertical growth of the maxilla. surgical approach becomes even harder. Therefore, possibility of intraosseous tooth migration should be considered as an important factor when deciding appropriate time for surgical extraction. We are presenting cases of mesiodens which showed intraosseous migration during 2~3 years of follow-up period since the first diagnosis had been made at the 6~7 years of age.

황복(Takifugu obscurus)에 대한 중금속, 유기주석화합물 및 다환방향족탄화수소(PAHs)의 급성 독성

이정석,이규태,김동훈,김진형,한경남 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.2

We exposed juvenile puffer fish, Takifugu obscurus(30 days after hatching) to various aqueous pollutants including 4 kinds of inorganic metals(Ag, Cd, Cu and Hg), 2 organotin compounds(tributyltin [TBT] and triphenyltin [TPhT]) and 5 polycyclic aromatic hydrocarbon(PAH) compounds(chrysene, fluoranthene, naphthalene, phenanthrene and pyrene) to estimate median lethal concentrations(LC50s) of each pollutant after the 96-hour acute exposure. Among the inorganic metals, Hg(52㎍/L; 96-h LC50) was most toxic to test animals and followed by Ag(164㎍/L), Cu(440㎍/L) and Cd(1180㎍/L). Aqueous TBT was more toxic between the two organotins; the 96-h LC50 for TBT(5.1㎍/L) was 3 times lower than that of TPhT(17.3㎍/L). The acute toxicity of PAH compounds was highest for chrysene(1.5㎍/L; 96-h LC50) and decreased in the order of pyrene(65㎍/L)>fluoranthene (158㎍/L)>phenanthrene(432㎍/L)>naphthalene(8690㎍/L). The toxicity of PAH compounds was closely related to their physico-chemical characteristics such as K_(ow) and water solubility, and well explained by simple QSAR relationship. The sensitivity of puffer fish to various inorganic and organic pollutants was generally comparable to various fish species widely used as standard test species in previous studies and further evaluation should be conducted to develop adequate testing procedures for T. obscurus when used in various toxicity tests.

포르피린증 환자에서 보인 가역적 자기공명영상소견 1례

강석윤,마효일,곽규환,이상암 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

중학교 과학과 학습내용 구성의 문제점과 그 개선 연구

이규석,우종옥 한국교원대학교 과학교육연구소 1991 청람과학교육연구논총 Vol.1 No.1

현행 중학교 과학과 교육과정 중 교육 내용의 선정과 조직상의 문제점을 추출하여 그 개선점을 논의하였다. 교육 내용의 선정과 조직상의 문제점은 교육과정을 구성할 때에 교육 내용의 선정과 조직에 관하여 일반적으로 요구되는 원리를 준거로 하고 우리 나라가 해방 후 오늘에 이르기까지 5차에 걸쳐 교육과정을 구성함에 있어서 중점적으로 강조하였던 점을 고려하여 추출하였다. 추출된 문제점의 개선 방향은 주로 그간 발표되었던 문헌을 중심으로 조사 분석하고 현장 교사의 의견을 조사하여 이를 바탕으로 논의를 하였다. 그리고 그 결과를 기초로 교육과정 내용 선정과 조직에서 나타난 문제점의 개선 방안의 일부를 제언하였다. The problem of contemporary curriculum is extracted by rationale of curriculum and our last nation's curricula in the middie school. As the results, it is problems in goals and learning contents, level and quantity of contents, ratio of science region, constitution's ratio of activity and information, experiments, practical science, content of science history and science and society, uniformity of contents, integrated science. The problem is analysed to study of improvement plan for the selection and organization of contents of science in the middle school. Resulting of these analyses this study states to improve plan for curriculum of middle school in Korea.

병원행정직직원의 보수만족에 영향을 미치는 요인

이영석,류구수 慶山大學校 保健福祉硏究所 1999 保健福祉硏究 Vol.2 No.-

After national insurance system is launched, the number of hospital managing staffs have been increased to cover the new demands. To justify their labor costs, hospitals need efficient control in wage level of their empolyees, especially in administrative personnel. This study aims to figure out factors associated with the degree of wage satisfaction of administrative personnel in hospitals. I survey 260 administrative personnel in 5 general hospitals for the study. The results are as follows. First, high level of wage is not always related with their satisfaction of wage level. The level of satisfaction is affected by demographics such as age, sex, education level, and etc... Second, the wage level of administrative personnel is higher than other industry. However, college graduates in hospitals receives less salary than other industry's. Therefore, hospitals should raise wage level for their college graduates employees. Finally, the service years of employees is highly related with the level of wage satisfaction. As working years goes by, the level of satisfactions reduced. Therefore, hospital managers should pay more salaries for employees who have been serving long period by developing payment system such as a longevity allowance.

Si-Schottky障壁型의 大陽電池 製作에 관한 硏究

李相潤,羅炳旭,朴德圭,李鍾德,金奎用,玄東杰,禹洪,盧景錫 慶北大學校 物理化學硏究所 1981 硏究論文集 Vol.1-2 No.-

The characteristics of these Si-schottky barrier type and Heterojunction type solar cells are as follows; 1. SnO_2/n-Si Heterojunction Solar Cells Fabricated by Spray Pyrolysis Method SnO_2 film were deposited on the (100) or (111) surface of Si single crystal by the spray pyrolysis method. The best SnO_2/n-Si solar cell has a good performance, with an open-circult voltage: Voc.=0.45V, short circuit current: Isc.=35.5㎃, fill factor: FF.=0.64, and conversion efficiency: η=10.2% under 98㎽/㎠ irradiation of AMl. The spray pyrolysis described in this paper is simple and suitable for mass production. One possibility for cost reduction lies in this method of junction fabrication, and the idea of simply deposited SnO_2/n-Si junction is, at first sight, very attractive. Hence the SnO_2/n-Si Solar Cell and the effectiveness of this method may be of great value in some future production of low-cost solar cells. 2. In_2O_3: Sn Heterojunction Solar Cells Fabricated by Spray Pyrolitic Method Highly conductive and transparent thin films of In_2O_3: Sn (ITO) are fabricated by spray pyrolytic method. The parameters of these thin films are as follows: resistivity ρ = 1.5×10 exp (-3) Ω·㎝, carrier concentration n = 7.5×10 exp (19) cm^-3, mobility μ = 55.5 ㎠/V·sec and transmission 85-90% over visible and long wave-length region. These thin films have simple cubic system with lattice constant 10.2Å. In_2O_3: Sn/n-Si heterojunction solar cells are fabricated, depositing In_2O_3: Sn (ITO) thin films on n-Si substrates with orientation(100) and resistively 2-3Ω, ㎝ by spray pyrolitic method. Under AMl sunlight simulator, the parameters of the excellent cell obtained has open-circuit voltage Voc=0.52V, short-circuit current I_sc=39.0㎃, fill factor: F.F=0.60 and conversion efficiencyη=12.1%. 3. Al/p-Si MOS Solar Cells Fabricated by Vacuum Evaporation Method Al/p-Si MOS solar cells, consisting of Al on P-tupe silicon with a thin interfacial layer of SiO_2 have been found to have good light conversion efficiency for solar radiation. The effects of the oxide layer thickness between metal and substrate were investigated. Under AMl simulated sunlight illumination the best cell has open circuit voltage Voc=0.50V, short-circuit current I_sc=26.3㎃/㎠, fill-factor FF=0.70 and conversion efficiency η=9.2%. 4. Cr-Cu/P-Si MOS Solar Cells Fabricated by Vacuum Evaporation Method Cr-Cu/p-Si MOS Solar cells, consisting of Cr-Cu on p-type silicon with a thin interfacial layer of SiO_2 have been found to have good light conversion efficiency for solar radiation. The effects of the oxide layer thickness between metal and substrate were investigated. Under AMl simulated sunlight illumination the best cell has open circuit voltage Voc=0.49V, short-circuit current I_sc=26.4㎃, fill-factor: FF=0.72 and conversion efficiency η=9.3%.

한글ㆍ영문 겸용 Word Processor System 개발에 관한 연구

이상인,강석건,서창렬,신태민,박규태,여재준,장이한 연세대학교 산업기술연구소 1984 논문집 Vol.16 No.2

The design theory and implementation of a word processor system with more efficient processing of Korean and English text are studied. A screen editing method is implemented which is more flexible to handle the texts. Convinient control of the keyboards, cursors moving, texts editing, line marking and block operations are considered. The codes to avoid the complexity and inefficiency which are caused by difference of the code length between the Korean and English characters are reconstructed. File management systems and algorithms for executing the control commands are also studied. As a result, a successful word processor system is designed and implemental which performs a complete screen editing system. The performance of the system includes flexible cursor movement, margin setting, block operations of insertion, deletion and copying any sizes of the line and blocks; and also, the printout routines for size variation of the characters are worked out.